4DGAC

Trimcyp cyclophilin domain from macaca mulatta: hiv-1 ca(o-loop) complex
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
145
structure length
138
Chain Sequence
PIVVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRTHPPAMGPLPPGQIREPTGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Macaca mulatta
molecule keywords TRIMCyp
total genus 48
structure length 138
sequence length 145
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2012-01-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4dgaC00
1M9FC 1D1DA 2KGFA 1M9EC 5HGNA 4DGEC 1AFVA 2M8LA 1M9CC 2PWOA 4PH0A 4XFXA 4PH2A 4U0FA 4NX4C 4E91A 4PH3A 3H47A 3P05A 5HGOA 4E92A 4B4NA 4LQWC 4QNBA 2XGVA 4U0DA 3MGEA 2Y4ZA 5JPAA 3BP9A 4U0EA 4U0CA 4HTWA 2V4XA 2GONA 1M9DC 2PXRC 4XFYA 2EIAA 1L6NA 4WYMA 1EM9A 2WLVA 2M8NA 1GWPA 4DGAC 2M8PA 5HGKA 2XGUA 1E6JP 1P7NA 5HGMA 2X2DD 1G03A 5HGLA 2XGYA 4U0BA 2GOLB 2X83A 1M9XC 1QRJA 4INBA 2LF4A 3NTEA 4XFZA 1EIAA 2JPRA 4XROA 2PWMA 2X82A 2WLVB 2XDEA 1M9YC 1U7KA 4XRQA 4U0AA 4J93A 3H4EA 1AK4C
chains in the Genus database with same CATH superfamily
1M9FC 1D1DA 2KGFA 1M9EC 5HGNA 4DGEC 1AFVA 2M8LA 1M9CC 2PWOA 4PH0A 4XFXA 4PH2A 4U0FA 4NX4C 4E91A 4PH3A 3H47A 3P05A 5HGOA 4E92A 4B4NA 4LQWC 4QNBA 2XGVA 4U0DA 3MGEA 2Y4ZA 5JPAA 3BP9A 4U0EA 4U0CA 4HTWA 2V4XA 2GONA 1M9DC 2PXRC 4XFYA 2EIAA 1L6NA 4WYMA 1EM9A 2WLVA 2M8NA 1GWPA 4DGAC 2M8PA 5HGKA 2XGUA 1E6JP 1P7NA 5HGMA 2X2DD 1G03A 5HGLA 2XGYA 4U0BA 2GOLB 2X83A 1M9XC 1QRJA 4INBA 2LF4A 3NTEA 4XFZA 1EIAA 2JPRA 4XROA 2PWMA 2X82A 2WLVB 2XDEA 1M9YC 1U7KA 4XRQA 4U0AA 4J93A 3H4EA 1AK4C
chains in the Genus database with same CATH topology
1M9FC 1D1DA 2KGFA 1M9EC 5HGNA 4DGEC 1AFVA 2M8LA 1M9CC 2PWOA 4PH0A 4XFXA 4PH2A 4U0FA 4NX4C 4E91A 4PH3A 3H47A 3P05A 5HGOA 4E92A 4B4NA 4LQWC 4QNBA 2XGVA 4U0DA 3MGEA 2Y4ZA 5JPAA 3BP9A 4U0EA 4U0CA 4HTWA 2V4XA 2GONA 1M9DC 2PXRC 4XFYA 2EIAA 1L6NA 4WYMA 1EM9A 2WLVA 2M8NA 1GWPA 4DGAC 2M8PA 5HGKA 2XGUA 1E6JP 1P7NA 5HGMA 2X2DD 1G03A 5HGLA 2XGYA 4U0BA 2GOLB 2X83A 1M9XC 1QRJA 4INBA 2LF4A 3NTEA 4XFZA 1EIAA 2JPRA 4XROA 2PWMA 2X82A 2WLVB 2XDEA 1M9YC 1U7KA 4XRQA 4U0AA 4J93A 3H4EA 1AK4C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M9F C;  1D1D A;  2KGF A;  1M9E C;  5HGN A;  4DGE C;  1AFV A;  2M8L A;  1M9C C;  2PWO A;  4PH0 A;  4XFX A;  4PH2 A;  4U0F A;  4NX4 C;  4E91 A;  4PH3 A;  3H47 A;  3P05 A;  5HGO A;  4E92 A;  4B4N A;  4LQW C;  4QNB A;  2XGV A;  4U0D A;  3MGE A;  2Y4Z A;  5JPA A;  3BP9 A;  4U0E A;  4U0C A;  4HTW A;  2V4X A;  2GON A;  1M9D C;  2PXR C;  4XFY A;  2EIA A;  1L6N A;  4WYM A;  1EM9 A;  2WLV A;  2M8N A;  1GWP A;  4DGA C;  2M8P A;  5HGK A;  2XGU A;  1E6J P;  1P7N A;  5HGM A;  2X2D D;  1G03 A;  5HGL A;  2XGY A;  4U0B A;  2GOL B;  2X83 A;  1M9X C;  1QRJ A;  4INB A;  2LF4 A;  3NTE A;  4XFZ A;  1EIA A;  2JPR A;  4XRO A;  2PWM A;  2X82 A;  2WLV B;  2XDE A;  1M9Y C;  1U7K A;  4XRQ A;  4U0A A;  4J93 A;  3H4E A;  1AK4 C; 
#chains in the Genus database with same CATH topology
 1M9F C;  1D1D A;  2KGF A;  1M9E C;  5HGN A;  4DGE C;  1AFV A;  2M8L A;  1M9C C;  2PWO A;  4PH0 A;  4XFX A;  4PH2 A;  4U0F A;  4NX4 C;  4E91 A;  4PH3 A;  3H47 A;  3P05 A;  5HGO A;  4E92 A;  4B4N A;  4LQW C;  4QNB A;  2XGV A;  4U0D A;  3MGE A;  2Y4Z A;  5JPA A;  3BP9 A;  4U0E A;  4U0C A;  4HTW A;  2V4X A;  2GON A;  1M9D C;  2PXR C;  4XFY A;  2EIA A;  1L6N A;  4WYM A;  1EM9 A;  2WLV A;  2M8N A;  1GWP A;  4DGA C;  2M8P A;  5HGK A;  2XGU A;  1E6J P;  1P7N A;  5HGM A;  2X2D D;  1G03 A;  5HGL A;  2XGY A;  4U0B A;  2GOL B;  2X83 A;  1M9X C;  1QRJ A;  4INB A;  2LF4 A;  3NTE A;  4XFZ A;  1EIA A;  2JPR A;  4XRO A;  2PWM A;  2X82 A;  2WLV B;  2XDE A;  1M9Y C;  1U7K A;  4XRQ A;  4U0A A;  4J93 A;  3H4E A;  1AK4 C; 
#chains in the Genus database with same CATH homology
 1M9F C;  1D1D A;  2KGF A;  1M9E C;  5HGN A;  4DGE C;  1AFV A;  2M8L A;  1M9C C;  2PWO A;  4PH0 A;  4XFX A;  4PH2 A;  4U0F A;  4NX4 C;  4E91 A;  4PH3 A;  3H47 A;  3P05 A;  5HGO A;  4E92 A;  4B4N A;  4LQW C;  4QNB A;  2XGV A;  4U0D A;  3MGE A;  2Y4Z A;  5JPA A;  3BP9 A;  4U0E A;  4U0C A;  4HTW A;  2V4X A;  2GON A;  1M9D C;  2PXR C;  4XFY A;  2EIA A;  1L6N A;  4WYM A;  1EM9 A;  2WLV A;  2M8N A;  1GWP A;  4DGA C;  2M8P A;  5HGK A;  2XGU A;  1E6J P;  1P7N A;  5HGM A;  2X2D D;  1G03 A;  5HGL A;  2XGY A;  4U0B A;  2GOL B;  2X83 A;  1M9X C;  1QRJ A;  4INB A;  2LF4 A;  3NTE A;  4XFZ A;  1EIA A;  2JPR A;  4XRO A;  2PWM A;  2X82 A;  2WLV B;  2XDE A;  1M9Y C;  1U7K A;  4XRQ A;  4U0A A;  4J93 A;  3H4E A;  1AK4 C; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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