4DGEC

Trimcyp cyclophilin domain from macaca mulatta: h70c mutant, hiv-1 ca(o-loop) complex
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
143
structure length
136
Chain Sequence
PIVVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRTHPPAMGPLPPGQIREPTGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Macaca mulatta
molecule keywords TRIMCyp
total genus 47
structure length 136
sequence length 143
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2012-01-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4dgeC00
4XFYA 5HGNA 4XFZA 1U7KA 2WLVB 1L6NA 5HGKA 2X82A 2XDEA 2WLVA 3MGEA 4QNBA 5JPAA 4PH0A 4E92A 1M9FC 1QRJA 1M9EC 4U0EA 4U0AA 2X83A 1EM9A 2Y4ZA 2PWMA 4HTWA 2PWOA 1GWPA 4E91A 3H4EA 2KGFA 2XGUA 3NTEA 2M8PA 3H47A 1D1DA 2X2DD 3P05A 4PH2A 4U0FA 2M8NA 2JPRA 1M9YC 4LQWC 2LF4A 2EIAA 2PXRC 2GOLB 1M9XC 4J93A 1AFVA 4B4NA 1EIAA 3BP9A 4U0BA 4DGEC 5HGLA 4XFXA 4WYMA 5HGOA 1M9DC 4INBA 4NX4C 2M8LA 4DGAC 2V4XA 4PH3A 1G03A 5HGMA 4XROA 4XRQA 1E6JP 2GONA 4U0DA 1P7NA 2XGVA 4U0CA 1M9CC 2XGYA 1AK4C
chains in the Genus database with same CATH superfamily
4XFYA 5HGNA 4XFZA 1U7KA 2WLVB 1L6NA 5HGKA 2X82A 2XDEA 2WLVA 3MGEA 4QNBA 5JPAA 4PH0A 4E92A 1M9FC 1QRJA 1M9EC 4U0EA 4U0AA 2X83A 1EM9A 2Y4ZA 2PWMA 4HTWA 2PWOA 1GWPA 4E91A 3H4EA 2KGFA 2XGUA 3NTEA 2M8PA 3H47A 1D1DA 2X2DD 3P05A 4PH2A 4U0FA 2M8NA 2JPRA 1M9YC 4LQWC 2LF4A 2EIAA 2PXRC 2GOLB 1M9XC 4J93A 1AFVA 4B4NA 1EIAA 3BP9A 4U0BA 4DGEC 5HGLA 4XFXA 4WYMA 5HGOA 1M9DC 4INBA 4NX4C 2M8LA 4DGAC 2V4XA 4PH3A 1G03A 5HGMA 4XROA 4XRQA 1E6JP 2GONA 4U0DA 1P7NA 2XGVA 4U0CA 1M9CC 2XGYA 1AK4C
chains in the Genus database with same CATH topology
4XFYA 5HGNA 4XFZA 1U7KA 2WLVB 1L6NA 5HGKA 2X82A 2XDEA 2WLVA 3MGEA 4QNBA 5JPAA 4PH0A 4E92A 1M9FC 1QRJA 1M9EC 4U0EA 4U0AA 2X83A 1EM9A 2Y4ZA 2PWMA 4HTWA 2PWOA 1GWPA 4E91A 3H4EA 2KGFA 2XGUA 3NTEA 2M8PA 3H47A 1D1DA 2X2DD 3P05A 4PH2A 4U0FA 2M8NA 2JPRA 1M9YC 4LQWC 2LF4A 2EIAA 2PXRC 2GOLB 1M9XC 4J93A 1AFVA 4B4NA 1EIAA 3BP9A 4U0BA 4DGEC 5HGLA 4XFXA 4WYMA 5HGOA 1M9DC 4INBA 4NX4C 2M8LA 4DGAC 2V4XA 4PH3A 1G03A 5HGMA 4XROA 4XRQA 1E6JP 2GONA 4U0DA 1P7NA 2XGVA 4U0CA 1M9CC 2XGYA 1AK4C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XFY A;  5HGN A;  4XFZ A;  1U7K A;  2WLV B;  1L6N A;  5HGK A;  2X82 A;  2XDE A;  2WLV A;  3MGE A;  4QNB A;  5JPA A;  4PH0 A;  4E92 A;  1M9F C;  1QRJ A;  1M9E C;  4U0E A;  4U0A A;  2X83 A;  1EM9 A;  2Y4Z A;  2PWM A;  4HTW A;  2PWO A;  1GWP A;  4E91 A;  3H4E A;  2KGF A;  2XGU A;  3NTE A;  2M8P A;  3H47 A;  1D1D A;  2X2D D;  3P05 A;  4PH2 A;  4U0F A;  2M8N A;  2JPR A;  1M9Y C;  4LQW C;  2LF4 A;  2EIA A;  2PXR C;  2GOL B;  1M9X C;  4J93 A;  1AFV A;  4B4N A;  1EIA A;  3BP9 A;  4U0B A;  4DGE C;  5HGL A;  4XFX A;  4WYM A;  5HGO A;  1M9D C;  4INB A;  4NX4 C;  2M8L A;  4DGA C;  2V4X A;  4PH3 A;  1G03 A;  5HGM A;  4XRO A;  4XRQ A;  1E6J P;  2GON A;  4U0D A;  1P7N A;  2XGV A;  4U0C A;  1M9C C;  2XGY A;  1AK4 C; 
#chains in the Genus database with same CATH topology
 4XFY A;  5HGN A;  4XFZ A;  1U7K A;  2WLV B;  1L6N A;  5HGK A;  2X82 A;  2XDE A;  2WLV A;  3MGE A;  4QNB A;  5JPA A;  4PH0 A;  4E92 A;  1M9F C;  1QRJ A;  1M9E C;  4U0E A;  4U0A A;  2X83 A;  1EM9 A;  2Y4Z A;  2PWM A;  4HTW A;  2PWO A;  1GWP A;  4E91 A;  3H4E A;  2KGF A;  2XGU A;  3NTE A;  2M8P A;  3H47 A;  1D1D A;  2X2D D;  3P05 A;  4PH2 A;  4U0F A;  2M8N A;  2JPR A;  1M9Y C;  4LQW C;  2LF4 A;  2EIA A;  2PXR C;  2GOL B;  1M9X C;  4J93 A;  1AFV A;  4B4N A;  1EIA A;  3BP9 A;  4U0B A;  4DGE C;  5HGL A;  4XFX A;  4WYM A;  5HGO A;  1M9D C;  4INB A;  4NX4 C;  2M8L A;  4DGA C;  2V4X A;  4PH3 A;  1G03 A;  5HGM A;  4XRO A;  4XRQ A;  1E6J P;  2GON A;  4U0D A;  1P7N A;  2XGV A;  4U0C A;  1M9C C;  2XGY A;  1AK4 C; 
#chains in the Genus database with same CATH homology
 4XFY A;  5HGN A;  4XFZ A;  1U7K A;  2WLV B;  1L6N A;  5HGK A;  2X82 A;  2XDE A;  2WLV A;  3MGE A;  4QNB A;  5JPA A;  4PH0 A;  4E92 A;  1M9F C;  1QRJ A;  1M9E C;  4U0E A;  4U0A A;  2X83 A;  1EM9 A;  2Y4Z A;  2PWM A;  4HTW A;  2PWO A;  1GWP A;  4E91 A;  3H4E A;  2KGF A;  2XGU A;  3NTE A;  2M8P A;  3H47 A;  1D1D A;  2X2D D;  3P05 A;  4PH2 A;  4U0F A;  2M8N A;  2JPR A;  1M9Y C;  4LQW C;  2LF4 A;  2EIA A;  2PXR C;  2GOL B;  1M9X C;  4J93 A;  1AFV A;  4B4N A;  1EIA A;  3BP9 A;  4U0B A;  4DGE C;  5HGL A;  4XFX A;  4WYM A;  5HGO A;  1M9D C;  4INB A;  4NX4 C;  2M8L A;  4DGA C;  2V4X A;  4PH3 A;  1G03 A;  5HGM A;  4XRO A;  4XRQ A;  1E6J P;  2GON A;  4U0D A;  1P7N A;  2XGV A;  4U0C A;  1M9C C;  2XGY A;  1AK4 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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