4E92A

Crystal structure of the n-terminal domain of hiv-1 capsid in complex with inhibitor bm4
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
146
structure length
140
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein.
pubmed doi rcsb
molecule tags Structural protein/inhibitor
source organism Human immunodeficiency virus 1
molecule keywords Gag protein
total genus 48
structure length 140
sequence length 146
chains with identical sequence B
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2012-03-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4e92A00
4U0DA 4E91A 3NTEA 4PH0A 1U7KA 1M9YC 2EIAA 2XDEA 4PH2A 2XGVA 4XRQA 1GWPA 4NX4C 5JPAA 2WLVA 4WYMA 1EM9A 4XROA 2V4XA 1E6JP 2M8PA 2WLVB 2X82A 2XGYA 4XFXA 1M9DC 2XGUA 4U0CA 2M8NA 4U0AA 5HGKA 3MGEA 4J93A 4LQWC 2GOLB 2GONA 1M9CC 1EIAA 4U0FA 1D1DA 1M9FC 2LF4A 4XFYA 4QNBA 5HGNA 4U0BA 1P7NA 4INBA 1G03A 4XFZA 1QRJA 3BP9A 2M8LA 4DGEC 5HGOA 2JPRA 2PWOA 3H47A 3P05A 1M9XC 4DGAC 4U0EA 1M9EC 2KGFA 2PXRC 2X2DD 5HGMA 1L6NA 5HGLA 4PH3A 3H4EA 4B4NA 2PWMA 2X83A 1AK4C 4E92A 1AFVA 2Y4ZA 4HTWA
chains in the Genus database with same CATH superfamily
4U0DA 4E91A 3NTEA 4PH0A 1U7KA 1M9YC 2EIAA 2XDEA 4PH2A 2XGVA 4XRQA 1GWPA 4NX4C 5JPAA 2WLVA 4WYMA 1EM9A 4XROA 2V4XA 1E6JP 2M8PA 2WLVB 2X82A 2XGYA 4XFXA 1M9DC 2XGUA 4U0CA 2M8NA 4U0AA 5HGKA 3MGEA 4J93A 4LQWC 2GOLB 2GONA 1M9CC 1EIAA 4U0FA 1D1DA 1M9FC 2LF4A 4XFYA 4QNBA 5HGNA 4U0BA 1P7NA 4INBA 1G03A 4XFZA 1QRJA 3BP9A 2M8LA 4DGEC 5HGOA 2JPRA 2PWOA 3H47A 3P05A 1M9XC 4DGAC 4U0EA 1M9EC 2KGFA 2PXRC 2X2DD 5HGMA 1L6NA 5HGLA 4PH3A 3H4EA 4B4NA 2PWMA 2X83A 1AK4C 4E92A 1AFVA 2Y4ZA 4HTWA
chains in the Genus database with same CATH topology
4U0DA 4E91A 3NTEA 4PH0A 1U7KA 1M9YC 2EIAA 2XDEA 4PH2A 2XGVA 4XRQA 1GWPA 4NX4C 5JPAA 2WLVA 4WYMA 1EM9A 4XROA 2V4XA 1E6JP 2M8PA 2WLVB 2X82A 2XGYA 4XFXA 1M9DC 2XGUA 4U0CA 2M8NA 4U0AA 5HGKA 3MGEA 4J93A 4LQWC 2GOLB 2GONA 1M9CC 1EIAA 4U0FA 1D1DA 1M9FC 2LF4A 4XFYA 4QNBA 5HGNA 4U0BA 1P7NA 4INBA 1G03A 4XFZA 1QRJA 3BP9A 2M8LA 4DGEC 5HGOA 2JPRA 2PWOA 3H47A 3P05A 1M9XC 4DGAC 4U0EA 1M9EC 2KGFA 2PXRC 2X2DD 5HGMA 1L6NA 5HGLA 4PH3A 3H4EA 4B4NA 2PWMA 2X83A 1AK4C 4E92A 1AFVA 2Y4ZA 4HTWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U0D A;  4E91 A;  3NTE A;  4PH0 A;  1U7K A;  1M9Y C;  2EIA A;  2XDE A;  4PH2 A;  2XGV A;  4XRQ A;  1GWP A;  4NX4 C;  5JPA A;  2WLV A;  4WYM A;  1EM9 A;  4XRO A;  2V4X A;  1E6J P;  2M8P A;  2WLV B;  2X82 A;  2XGY A;  4XFX A;  1M9D C;  2XGU A;  4U0C A;  2M8N A;  4U0A A;  5HGK A;  3MGE A;  4J93 A;  4LQW C;  2GOL B;  2GON A;  1M9C C;  1EIA A;  4U0F A;  1D1D A;  1M9F C;  2LF4 A;  4XFY A;  4QNB A;  5HGN A;  4U0B A;  1P7N A;  4INB A;  1G03 A;  4XFZ A;  1QRJ A;  3BP9 A;  2M8L A;  4DGE C;  5HGO A;  2JPR A;  2PWO A;  3H47 A;  3P05 A;  1M9X C;  4DGA C;  4U0E A;  1M9E C;  2KGF A;  2PXR C;  2X2D D;  5HGM A;  1L6N A;  5HGL A;  4PH3 A;  3H4E A;  4B4N A;  2PWM A;  2X83 A;  1AK4 C;  4E92 A;  1AFV A;  2Y4Z A;  4HTW A; 
#chains in the Genus database with same CATH topology
 4U0D A;  4E91 A;  3NTE A;  4PH0 A;  1U7K A;  1M9Y C;  2EIA A;  2XDE A;  4PH2 A;  2XGV A;  4XRQ A;  1GWP A;  4NX4 C;  5JPA A;  2WLV A;  4WYM A;  1EM9 A;  4XRO A;  2V4X A;  1E6J P;  2M8P A;  2WLV B;  2X82 A;  2XGY A;  4XFX A;  1M9D C;  2XGU A;  4U0C A;  2M8N A;  4U0A A;  5HGK A;  3MGE A;  4J93 A;  4LQW C;  2GOL B;  2GON A;  1M9C C;  1EIA A;  4U0F A;  1D1D A;  1M9F C;  2LF4 A;  4XFY A;  4QNB A;  5HGN A;  4U0B A;  1P7N A;  4INB A;  1G03 A;  4XFZ A;  1QRJ A;  3BP9 A;  2M8L A;  4DGE C;  5HGO A;  2JPR A;  2PWO A;  3H47 A;  3P05 A;  1M9X C;  4DGA C;  4U0E A;  1M9E C;  2KGF A;  2PXR C;  2X2D D;  5HGM A;  1L6N A;  5HGL A;  4PH3 A;  3H4E A;  4B4N A;  2PWM A;  2X83 A;  1AK4 C;  4E92 A;  1AFV A;  2Y4Z A;  4HTW A; 
#chains in the Genus database with same CATH homology
 4U0D A;  4E91 A;  3NTE A;  4PH0 A;  1U7K A;  1M9Y C;  2EIA A;  2XDE A;  4PH2 A;  2XGV A;  4XRQ A;  1GWP A;  4NX4 C;  5JPA A;  2WLV A;  4WYM A;  1EM9 A;  4XRO A;  2V4X A;  1E6J P;  2M8P A;  2WLV B;  2X82 A;  2XGY A;  4XFX A;  1M9D C;  2XGU A;  4U0C A;  2M8N A;  4U0A A;  5HGK A;  3MGE A;  4J93 A;  4LQW C;  2GOL B;  2GON A;  1M9C C;  1EIA A;  4U0F A;  1D1D A;  1M9F C;  2LF4 A;  4XFY A;  4QNB A;  5HGN A;  4U0B A;  1P7N A;  4INB A;  1G03 A;  4XFZ A;  1QRJ A;  3BP9 A;  2M8L A;  4DGE C;  5HGO A;  2JPR A;  2PWO A;  3H47 A;  3P05 A;  1M9X C;  4DGA C;  4U0E A;  1M9E C;  2KGF A;  2PXR C;  2X2D D;  5HGM A;  1L6N A;  5HGL A;  4PH3 A;  3H4E A;  4B4N A;  2PWM A;  2X83 A;  1AK4 C;  4E92 A;  1AFV A;  2Y4Z A;  4HTW A; 
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