1M1KJ

Co-crystal structure of azithromycin bound to the 50s ribosomal subunit of haloarcula marismortui
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
167
structure length
156
Chain Sequence
KPGAMYRNSSKPAYTRREYISGIPGKKIAQFDMGNNGAGPTYPAQVELVVEKPVQIRHNALEAARVAANRYVQNSGAAANYKFRIRKFPFHVIRENKDGMRAPFGKPVGTAARVHGANHIFIAWVNPDPNVEEAWRRAKMKVTPTINIDSSPAGNA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structures of four macrolide antibiotics bound to the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RRNA
total genus 27
structure length 156
sequence length 167
ec nomenclature
pdb deposition date 2002-06-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1m1kJ00
2ZJQJ 5JVHJ 1Y69K 4WF9J 5GADN 1K9MJ 3CCEH 3CC4H 3PIOJ 1Q81J 1YI2H 3CMAH 3CXCH 3CCUH 1YJWH 4WCEJ 4UY8M 1WKIA 1NJIJ 1K73J 2QA4H 3PIPJ 3CCSH 1W2BH 1KC8J 1VQLH 4IOAJ 1M1KJ 3CC7H 1Q86J 2ZJRJ 4WFBJ 1YJNH 1Q7YJ 2ZJPJ 1VQ7H 2OTJH 3I56H 3CCLH 5GAHN 1VQOH 1M90J 5GAGN 1VQ9H 5H1SO 1YITH 2OTLH 1YJ9H 5HL7J 1VQ6H 3CCRH 4U67J 3CCVH 1YIJH 3G6EH 3CCQH 1VQ4H 3OW2H 4IO9J 1QVGH 3J7ZM 1VQNH 1K8AJ 1VQ5H 3DLLJ 5DM6J 5GAEN 3G71H 1KD1J 5DM7J 3CF5J 3G4SH 1YHQH 1S72H 1JJ2H 1VQ8H 3CPWH 3I55H 1Q82J 5AN9F 4WFAJ 2PA2A 3CCJH 5MLCO 3CCMH 1VQKH 3CMEH 4IOCJ 3CD6H 1N8RJ 2QEXH 1QVFH 1VQPH 4WFNJ 1VQMH 1KQSH 5JVGJ 3CC2H
chains in the Genus database with same CATH superfamily
2ZJQJ 5JVHJ 5HUOA 1VLBA 2W54B 1Y69K 3AMZA 3ETRC 5GADN 4WF9J 1K9MJ 1YTKA 3CCEH 3SR6C 3CC4H 4XR5A 2TPTA 3PIOJ 4AP8A 1Q81J 4GA5A 3C2EA 4X46A 3NRZC 1OTPA 2WP4A 4EADA 1JRPB 1N62B 1RM6A 1YI2H 2I14A 3CMAH 2JBMA 1N5XA 2E3TA 3PAJA 4C7YA 3CXCH 3L0GA 3CCUH 1SIJA 1YJWH 4WCEJ 4UY8M 2B7NA 3L4PA 3NVYC 5EP8A 2J0FA 1WKIA 5HUPA 3TQVA 1FM0E 4USAA 2WK6A 3C2RA 1NJIJ 2Q5WE 1K73J 2DSJA 1FO4A 2QA4H 1QAPA 5EY3A 3NS1C 3RPFA 3PIPJ 3CCSH 1W2BH 4EAFA 1KC8J 3WO1A 1NVIE 1DGJA 1QPRA 1VQLH 4IOAJ 1M1KJ 3CC7H 4I9AA 1Q86J 2ZJRJ 1FFVB 4WFBJ 3C2VA 5AYYA 1FMAE 1YJNH 1Q7YJ 2ZJPJ 1VQ7H 1QPQA 2OTJH 1N63B 2W55B 3I56H 3CCLH 3NVWC 3C2FA 5GAHN 1VDVA 2WK5A 4YEKA 4ZOHA 1VQOH 1M90J 5GAGN 1VQ9H 5H1SO 4C7ZA 1ZXIB 1YITH 2OTLH 5HULA 1YJ9H 5HL7J 1FIQC 1VQ6H 1YTDA 3CCRH 4YYYA 1N60B 3FAHA 4U67J 2W3SB 2W3RB 4US9A 1V97A 3CCVH 1YIJH 1FFUB 3FC4A 3AM9A 1SB3A 3G6EH 1O4UA 3CCQH 1VQ4H 4KWWA 3OW2H 1BRWA 1QPNA 4IO9J 1QVGH 3J7ZM 1VQNH 1K8AJ 1VQ5H 4C80A 3DLLJ 4US8A 1NVJA 5DM6J 5GAEN 1X1OA 1QPOA 2OMDA 1UOUA 3G71H 1KD1J 5DM7J 2B7QA 4LHMA 5AYXA 5MPOC 4GA6A 3CF5J 1N5WB 3G4SH 1YHQH 1WYGA 1S72H 1JJ2H 3VMMA 2QIEA 1N61B 1VQ8H 3EUB4 3CPWH 3NVVC 3I55H 3BIIE 1Q82J 5AN9F 3WNZA 4WFAJ 2PA2A 1JROB 3CCJH 1YTEA 5MLCO 3CCMH 2B7PA 1VQKH 3CMEH 3AN1A 3C2OA 3H5QA 3B9JC 4IOCJ 1AZYA 4GA4A 3GNNA 3CD6H 1N8RJ 2QEXH 1QVFH 2I1OA 1VQPH 4WFNJ 1VQMH 1KQSH 3NVZC 5JVGJ 3CC2H 3WO0A 5AYZA 4KWVA
chains in the Genus database with same CATH topology
2ZJQJ 5JVHJ 1Y69K 4WF9J 5GADN 1K9MJ 3CCEH 3CC4H 3PIOJ 1Q81J 1YI2H 3CMAH 3CXCH 3CCUH 1YJWH 4WCEJ 4UY8M 1WKIA 1NJIJ 1K73J 2QA4H 3PIPJ 3CCSH 1W2BH 1KC8J 1VQLH 4IOAJ 1M1KJ 3CC7H 1Q86J 2ZJRJ 4WFBJ 1YJNH 1Q7YJ 2ZJPJ 1VQ7H 2OTJH 3I56H 3CCLH 5GAHN 1VQOH 1M90J 5GAGN 1VQ9H 5H1SO 1YITH 2OTLH 1YJ9H 5HL7J 1VQ6H 3CCRH 4U67J 3CCVH 1YIJH 3G6EH 3CCQH 1VQ4H 3OW2H 4IO9J 1QVGH 3J7ZM 1VQNH 1K8AJ 1VQ5H 3DLLJ 5DM6J 5GAEN 3G71H 1KD1J 5DM7J 3CF5J 3G4SH 1YHQH 1S72H 1JJ2H 1VQ8H 3CPWH 3I55H 1Q82J 5AN9F 4WFAJ 2PA2A 3CCJH 5MLCO 3CCMH 1VQKH 3CMEH 4IOCJ 3CD6H 1N8RJ 2QEXH 1QVFH 1VQPH 4WFNJ 1VQMH 1KQSH 5JVGJ 3CC2H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZJQ J;  5JVH J;  1Y69 K;  4WF9 J;  5GAD N;  1K9M J;  3CCE H;  3CC4 H;  3PIO J;  1Q81 J;  1YI2 H;  3CMA H;  3CXC H;  3CCU H;  1YJW H;  4WCE J;  4UY8 M;  1WKI A;  1NJI J;  1K73 J;  2QA4 H;  3PIP J;  3CCS H;  1W2B H;  1KC8 J;  1VQL H;  4IOA J;  1M1K J;  3CC7 H;  1Q86 J;  2ZJR J;  4WFB J;  1YJN H;  1Q7Y J;  2ZJP J;  1VQ7 H;  2OTJ H;  3I56 H;  3CCL H;  5GAH N;  1VQO H;  1M90 J;  5GAG N;  1VQ9 H;  5H1S O;  1YIT H;  2OTL H;  1YJ9 H;  5HL7 J;  1VQ6 H;  3CCR H;  4U67 J;  3CCV H;  1YIJ H;  3G6E H;  3CCQ H;  1VQ4 H;  3OW2 H;  4IO9 J;  1QVG H;  3J7Z M;  1VQN H;  1K8A J;  1VQ5 H;  3DLL J;  5DM6 J;  5GAE N;  3G71 H;  1KD1 J;  5DM7 J;  3CF5 J;  3G4S H;  1YHQ H;  1S72 H;  1JJ2 H;  1VQ8 H;  3CPW H;  3I55 H;  1Q82 J;  5AN9 F;  4WFA J;  2PA2 A;  3CCJ H;  5MLC O;  3CCM H;  1VQK H;  3CME H;  4IOC J;  3CD6 H;  1N8R J;  2QEX H;  1QVF H;  1VQP H;  4WFN J;  1VQM H;  1KQS H;  5JVG J;  3CC2 H; 
#chains in the Genus database with same CATH topology
 2ZJQ J;  5JVH J;  5HUO A;  1VLB A;  2W54 B;  1Y69 K;  3AMZ A;  3ETR C;  5GAD N;  4WF9 J;  1K9M J;  1YTK A;  3CCE H;  3SR6 C;  3CC4 H;  4XR5 A;  2TPT A;  3PIO J;  4AP8 A;  1Q81 J;  4GA5 A;  3C2E A;  4X46 A;  3NRZ C;  1OTP A;  2WP4 A;  4EAD A;  1JRP B;  1N62 B;  1RM6 A;  1YI2 H;  2I14 A;  3CMA H;  2JBM A;  1N5X A;  2E3T A;  3PAJ A;  4C7Y A;  3CXC H;  3L0G A;  3CCU H;  1SIJ A;  1YJW H;  4WCE J;  4UY8 M;  2B7N A;  3L4P A;  3NVY C;  5EP8 A;  2J0F A;  1WKI A;  5HUP A;  3TQV A;  1FM0 E;  4USA A;  2WK6 A;  3C2R A;  1NJI J;  2Q5W E;  1K73 J;  2DSJ A;  1FO4 A;  2QA4 H;  1QAP A;  5EY3 A;  3NS1 C;  3RPF A;  3PIP J;  3CCS H;  1W2B H;  4EAF A;  1KC8 J;  3WO1 A;  1NVI E;  1DGJ A;  1QPR A;  1VQL H;  4IOA J;  1M1K J;  3CC7 H;  4I9A A;  1Q86 J;  2ZJR J;  1FFV B;  4WFB J;  3C2V A;  5AYY A;  1FMA E;  1YJN H;  1Q7Y J;  2ZJP J;  1VQ7 H;  1QPQ A;  2OTJ H;  1N63 B;  2W55 B;  3I56 H;  3CCL H;  3NVW C;  3C2F A;  5GAH N;  1VDV A;  2WK5 A;  4YEK A;  4ZOH A;  1VQO H;  1M90 J;  5GAG N;  1VQ9 H;  5H1S O;  4C7Z A;  1ZXI B;  1YIT H;  2OTL H;  5HUL A;  1YJ9 H;  5HL7 J;  1FIQ C;  1VQ6 H;  1YTD A;  3CCR H;  4YYY A;  1N60 B;  3FAH A;  4U67 J;  2W3S B;  2W3R B;  4US9 A;  1V97 A;  3CCV H;  1YIJ H;  1FFU B;  3FC4 A;  3AM9 A;  1SB3 A;  3G6E H;  1O4U A;  3CCQ H;  1VQ4 H;  4KWW A;  3OW2 H;  1BRW A;  1QPN A;  4IO9 J;  1QVG H;  3J7Z M;  1VQN H;  1K8A J;  1VQ5 H;  4C80 A;  3DLL J;  4US8 A;  1NVJ A;  5DM6 J;  5GAE N;  1X1O A;  1QPO A;  2OMD A;  1UOU A;  3G71 H;  1KD1 J;  5DM7 J;  2B7Q A;  4LHM A;  5AYX A;  5MPO C;  4GA6 A;  3CF5 J;  1N5W B;  3G4S H;  1YHQ H;  1WYG A;  1S72 H;  1JJ2 H;  3VMM A;  2QIE A;  1N61 B;  1VQ8 H;  3EUB 4;  3CPW H;  3NVV C;  3I55 H;  3BII E;  1Q82 J;  5AN9 F;  3WNZ A;  4WFA J;  2PA2 A;  1JRO B;  3CCJ H;  1YTE A;  5MLC O;  3CCM H;  2B7P A;  1VQK H;  3CME H;  3AN1 A;  3C2O A;  3H5Q A;  3B9J C;  4IOC J;  1AZY A;  4GA4 A;  3GNN A;  3CD6 H;  1N8R J;  2QEX H;  1QVF H;  2I1O A;  1VQP H;  4WFN J;  1VQM H;  1KQS H;  3NVZ C;  5JVG J;  3CC2 H;  3WO0 A;  5AYZ A;  4KWV A; 
#chains in the Genus database with same CATH homology
 2ZJQ J;  5JVH J;  1Y69 K;  4WF9 J;  5GAD N;  1K9M J;  3CCE H;  3CC4 H;  3PIO J;  1Q81 J;  1YI2 H;  3CMA H;  3CXC H;  3CCU H;  1YJW H;  4WCE J;  4UY8 M;  1WKI A;  1NJI J;  1K73 J;  2QA4 H;  3PIP J;  3CCS H;  1W2B H;  1KC8 J;  1VQL H;  4IOA J;  1M1K J;  3CC7 H;  1Q86 J;  2ZJR J;  4WFB J;  1YJN H;  1Q7Y J;  2ZJP J;  1VQ7 H;  2OTJ H;  3I56 H;  3CCL H;  5GAH N;  1VQO H;  1M90 J;  5GAG N;  1VQ9 H;  5H1S O;  1YIT H;  2OTL H;  1YJ9 H;  5HL7 J;  1VQ6 H;  3CCR H;  4U67 J;  3CCV H;  1YIJ H;  3G6E H;  3CCQ H;  1VQ4 H;  3OW2 H;  4IO9 J;  1QVG H;  3J7Z M;  1VQN H;  1K8A J;  1VQ5 H;  3DLL J;  5DM6 J;  5GAE N;  3G71 H;  1KD1 J;  5DM7 J;  3CF5 J;  3G4S H;  1YHQ H;  1S72 H;  1JJ2 H;  1VQ8 H;  3CPW H;  3I55 H;  1Q82 J;  5AN9 F;  4WFA J;  2PA2 A;  3CCJ H;  5MLC O;  3CCM H;  1VQK H;  3CME H;  4IOC J;  3CD6 H;  1N8R J;  2QEX H;  1QVF H;  1VQP H;  4WFN J;  1VQM H;  1KQS H;  5JVG J;  3CC2 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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