3G4SH

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
molecule tags Ribosome
total genus 24
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2009-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3g4sH00
1YITH 1JJ2H 1VQOH 3CD6H 3CMEH 2ZJPJ 1KQSH 3G4SH 2QEXH 1QVGH 3CCRH 1Q82J 3CC2H 1Q7YJ 5JVGJ 1KC8J 3J7ZM 1M1KJ 1K8AJ 3CCJH 3CCVH 3DLLJ 5GAHN 4U67J 3CCLH 3CCSH 3CXCH 1YJ9H 2OTLH 5AN9F 1VQMH 3CCUH 1YIJH 1Q86J 1Y69K 1NJIJ 1Q81J 1VQPH 4WFAJ 5GAEN 1YHQH 5DM6J 4IOCJ 1QVFH 3CMAH 1K73J 1VQ9H 1WKIA 4WF9J 3CCMH 1VQ4H 4IOAJ 1M90J 4WFBJ 3I55H 3PIOJ 4WCEJ 3CC4H 3PIPJ 3OW2H 2ZJQJ 3G6EH 5HL7J 5MLCO 2PA2A 3CPWH 1VQLH 3CC7H 3G71H 2OTJH 1YJNH 1VQ6H 5JVHJ 1YJWH 4WFNJ 4IO9J 1VQ7H 2ZJRJ 1VQ8H 1VQKH 1KD1J 1N8RJ 2QA4H 1W2BH 1VQ5H 1VQNH 5GADN 4UY8M 5DM7J 1YI2H 3CCQH 5GAGN 3I56H 1K9MJ 5H1SO 3CCEH 1S72H 3CF5J
chains in the Genus database with same CATH superfamily
2QIEA 3FC4A 1QPNA 1YITH 1JJ2H 3WO1A 1VQOH 1QPOA 3CD6H 3CMEH 2ZJPJ 1KQSH 3NRZC 1N5XA 3SR6C 1QPQA 2TPTA 3NVZC 3G4SH 2I1OA 2QEXH 3BIIE 1QVGH 3CCRH 1RM6A 1Q82J 4GA4A 3CC2H 1Q7YJ 5JVGJ 3C2EA 4YYYA 3J7ZM 1KC8J 1M1KJ 1K8AJ 1FFUB 1AZYA 3CCVH 4EADA 3CCJH 3DLLJ 2B7NA 5GAHN 4U67J 2WK5A 3CCLH 3CCSH 1FFVB 4KWWA 3CXCH 1SB3A 2WK6A 4EAFA 1YJ9H 3FAHA 3TQVA 5AN9F 1VQMH 2OTLH 1YTKA 4ZOHA 3CCUH 4US8A 1YIJH 2JBMA 2WP4A 1Q86J 3VMMA 1N61B 4C80A 1DGJA 2W3RB 4LHMA 3ETRC 1Y69K 1NJIJ 3NVWC 1Q81J 1VQPH 1FMAE 4WFAJ 5GAEN 1YHQH 1YTEA 3NVYC 1BRWA 3PAJA 5DM6J 4IOCJ 1QVFH 5HUOA 3CMAH 1K73J 2J0FA 1WKIA 1VQ9H 4WF9J 1YTDA 3CCMH 1VQ4H 4IOAJ 3AMZA 1M90J 3GNNA 4WFBJ 1V97A 1N62B 1JROB 3AM9A 4GA6A 5HUPA 1UOUA 5EP8A 1OTPA 4US9A 3I55H 3PIOJ 4WCEJ 3CC4H 3PIPJ 3OW2H 3EUB4 1X1OA 1FIQC 5AYZA 5EY3A 1FM0E 5AYXA 2ZJQJ 1QPRA 2B7PA 3G6EH 2W3SB 5HL7J 5MLCO 1VDVA 4X46A 3WO0A 4AP8A 4I9AA 3B9JC 2DSJA 3AN1A 2PA2A 4XR5A 2OMDA 1N63B 3C2OA 3CPWH 3NS1C 1N5WB 1VQLH 3CC7H 1FO4A 1N60B 3G71H 2OTJH 1WYGA 5MPOC 1ZXIB 1YJNH 5AYYA 1JRPB 1VQ6H 2W54B 3C2RA 2E3TA 5JVHJ 1YJWH 4KWVA 3C2VA 4WFNJ 4IO9J 1NVIE 4GA5A 1VQ7H 2ZJRJ 1VQ8H 1VQKH 1QAPA 3L4PA 1KD1J 1N8RJ 1NVJA 1SIJA 5HULA 3C2FA 1VLBA 2QA4H 4YEKA 1W2BH 1VQ5H 3NVVC 1VQNH 5GADN 2Q5WE 1O4UA 3WNZA 3H5QA 4UY8M 5DM7J 2I14A 4C7ZA 2B7QA 1YI2H 3L0GA 3CCQH 5GAGN 4USAA 3RPFA 3I56H 1K9MJ 5H1SO 3CCEH 1S72H 4C7YA 2W55B 3CF5J
chains in the Genus database with same CATH topology
1YITH 1JJ2H 1VQOH 3CD6H 3CMEH 2ZJPJ 1KQSH 3G4SH 2QEXH 1QVGH 3CCRH 1Q82J 3CC2H 1Q7YJ 5JVGJ 1KC8J 3J7ZM 1M1KJ 1K8AJ 3CCJH 3CCVH 3DLLJ 5GAHN 4U67J 3CCLH 3CCSH 3CXCH 1YJ9H 2OTLH 5AN9F 1VQMH 3CCUH 1YIJH 1Q86J 1Y69K 1NJIJ 1Q81J 1VQPH 4WFAJ 5GAEN 1YHQH 5DM6J 4IOCJ 1QVFH 3CMAH 1K73J 1VQ9H 1WKIA 4WF9J 3CCMH 1VQ4H 4IOAJ 1M90J 4WFBJ 3I55H 3PIOJ 4WCEJ 3CC4H 3PIPJ 3OW2H 2ZJQJ 3G6EH 5HL7J 5MLCO 2PA2A 3CPWH 1VQLH 3CC7H 3G71H 2OTJH 1YJNH 1VQ6H 5JVHJ 1YJWH 4WFNJ 4IO9J 1VQ7H 2ZJRJ 1VQ8H 1VQKH 1KD1J 1N8RJ 2QA4H 1W2BH 1VQ5H 1VQNH 5GADN 4UY8M 5DM7J 1YI2H 3CCQH 5GAGN 3I56H 1K9MJ 5H1SO 3CCEH 1S72H 3CF5J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YIT H;  1JJ2 H;  1VQO H;  3CD6 H;  3CME H;  2ZJP J;  1KQS H;  3G4S H;  2QEX H;  1QVG H;  3CCR H;  1Q82 J;  3CC2 H;  1Q7Y J;  5JVG J;  1KC8 J;  3J7Z M;  1M1K J;  1K8A J;  3CCJ H;  3CCV H;  3DLL J;  5GAH N;  4U67 J;  3CCL H;  3CCS H;  3CXC H;  1YJ9 H;  2OTL H;  5AN9 F;  1VQM H;  3CCU H;  1YIJ H;  1Q86 J;  1Y69 K;  1NJI J;  1Q81 J;  1VQP H;  4WFA J;  5GAE N;  1YHQ H;  5DM6 J;  4IOC J;  1QVF H;  3CMA H;  1K73 J;  1VQ9 H;  1WKI A;  4WF9 J;  3CCM H;  1VQ4 H;  4IOA J;  1M90 J;  4WFB J;  3I55 H;  3PIO J;  4WCE J;  3CC4 H;  3PIP J;  3OW2 H;  2ZJQ J;  3G6E H;  5HL7 J;  5MLC O;  2PA2 A;  3CPW H;  1VQL H;  3CC7 H;  3G71 H;  2OTJ H;  1YJN H;  1VQ6 H;  5JVH J;  1YJW H;  4WFN J;  4IO9 J;  1VQ7 H;  2ZJR J;  1VQ8 H;  1VQK H;  1KD1 J;  1N8R J;  2QA4 H;  1W2B H;  1VQ5 H;  1VQN H;  5GAD N;  4UY8 M;  5DM7 J;  1YI2 H;  3CCQ H;  5GAG N;  3I56 H;  1K9M J;  5H1S O;  3CCE H;  1S72 H;  3CF5 J; 
#chains in the Genus database with same CATH topology
 2QIE A;  3FC4 A;  1QPN A;  1YIT H;  1JJ2 H;  3WO1 A;  1VQO H;  1QPO A;  3CD6 H;  3CME H;  2ZJP J;  1KQS H;  3NRZ C;  1N5X A;  3SR6 C;  1QPQ A;  2TPT A;  3NVZ C;  3G4S H;  2I1O A;  2QEX H;  3BII E;  1QVG H;  3CCR H;  1RM6 A;  1Q82 J;  4GA4 A;  3CC2 H;  1Q7Y J;  5JVG J;  3C2E A;  4YYY A;  3J7Z M;  1KC8 J;  1M1K J;  1K8A J;  1FFU B;  1AZY A;  3CCV H;  4EAD A;  3CCJ H;  3DLL J;  2B7N A;  5GAH N;  4U67 J;  2WK5 A;  3CCL H;  3CCS H;  1FFV B;  4KWW A;  3CXC H;  1SB3 A;  2WK6 A;  4EAF A;  1YJ9 H;  3FAH A;  3TQV A;  5AN9 F;  1VQM H;  2OTL H;  1YTK A;  4ZOH A;  3CCU H;  4US8 A;  1YIJ H;  2JBM A;  2WP4 A;  1Q86 J;  3VMM A;  1N61 B;  4C80 A;  1DGJ A;  2W3R B;  4LHM A;  3ETR C;  1Y69 K;  1NJI J;  3NVW C;  1Q81 J;  1VQP H;  1FMA E;  4WFA J;  5GAE N;  1YHQ H;  1YTE A;  3NVY C;  1BRW A;  3PAJ A;  5DM6 J;  4IOC J;  1QVF H;  5HUO A;  3CMA H;  1K73 J;  2J0F A;  1WKI A;  1VQ9 H;  4WF9 J;  1YTD A;  3CCM H;  1VQ4 H;  4IOA J;  3AMZ A;  1M90 J;  3GNN A;  4WFB J;  1V97 A;  1N62 B;  1JRO B;  3AM9 A;  4GA6 A;  5HUP A;  1UOU A;  5EP8 A;  1OTP A;  4US9 A;  3I55 H;  3PIO J;  4WCE J;  3CC4 H;  3PIP J;  3OW2 H;  3EUB 4;  1X1O A;  1FIQ C;  5AYZ A;  5EY3 A;  1FM0 E;  5AYX A;  2ZJQ J;  1QPR A;  2B7P A;  3G6E H;  2W3S B;  5HL7 J;  5MLC O;  1VDV A;  4X46 A;  3WO0 A;  4AP8 A;  4I9A A;  3B9J C;  2DSJ A;  3AN1 A;  2PA2 A;  4XR5 A;  2OMD A;  1N63 B;  3C2O A;  3CPW H;  3NS1 C;  1N5W B;  1VQL H;  3CC7 H;  1FO4 A;  1N60 B;  3G71 H;  2OTJ H;  1WYG A;  5MPO C;  1ZXI B;  1YJN H;  5AYY A;  1JRP B;  1VQ6 H;  2W54 B;  3C2R A;  2E3T A;  5JVH J;  1YJW H;  4KWV A;  3C2V A;  4WFN J;  4IO9 J;  1NVI E;  4GA5 A;  1VQ7 H;  2ZJR J;  1VQ8 H;  1VQK H;  1QAP A;  3L4P A;  1KD1 J;  1N8R J;  1NVJ A;  1SIJ A;  5HUL A;  3C2F A;  1VLB A;  2QA4 H;  4YEK A;  1W2B H;  1VQ5 H;  3NVV C;  1VQN H;  5GAD N;  2Q5W E;  1O4U A;  3WNZ A;  3H5Q A;  4UY8 M;  5DM7 J;  2I14 A;  4C7Z A;  2B7Q A;  1YI2 H;  3L0G A;  3CCQ H;  5GAG N;  4USA A;  3RPF A;  3I56 H;  1K9M J;  5H1S O;  3CCE H;  1S72 H;  4C7Y A;  2W55 B;  3CF5 J; 
#chains in the Genus database with same CATH homology
 1YIT H;  1JJ2 H;  1VQO H;  3CD6 H;  3CME H;  2ZJP J;  1KQS H;  3G4S H;  2QEX H;  1QVG H;  3CCR H;  1Q82 J;  3CC2 H;  1Q7Y J;  5JVG J;  1KC8 J;  3J7Z M;  1M1K J;  1K8A J;  3CCJ H;  3CCV H;  3DLL J;  5GAH N;  4U67 J;  3CCL H;  3CCS H;  3CXC H;  1YJ9 H;  2OTL H;  5AN9 F;  1VQM H;  3CCU H;  1YIJ H;  1Q86 J;  1Y69 K;  1NJI J;  1Q81 J;  1VQP H;  4WFA J;  5GAE N;  1YHQ H;  5DM6 J;  4IOC J;  1QVF H;  3CMA H;  1K73 J;  1VQ9 H;  1WKI A;  4WF9 J;  3CCM H;  1VQ4 H;  4IOA J;  1M90 J;  4WFB J;  3I55 H;  3PIO J;  4WCE J;  3CC4 H;  3PIP J;  3OW2 H;  2ZJQ J;  3G6E H;  5HL7 J;  5MLC O;  2PA2 A;  3CPW H;  1VQL H;  3CC7 H;  3G71 H;  2OTJ H;  1YJN H;  1VQ6 H;  5JVH J;  1YJW H;  4WFN J;  4IO9 J;  1VQ7 H;  2ZJR J;  1VQ8 H;  1VQK H;  1KD1 J;  1N8R J;  2QA4 H;  1W2B H;  1VQ5 H;  1VQN H;  5GAD N;  4UY8 M;  5DM7 J;  1YI2 H;  3CCQ H;  5GAG N;  3I56 H;  1K9M J;  5H1S O;  3CCE H;  1S72 H;  3CF5 J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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