1YI2H

Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule keywords 23S Ribosomal RNA
total genus 39
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2005-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1yi2H00
3CC7H 1KC8J 1YITH 1Q82J 3CPWH 3CCRH 1Q81J 1YJNH 5JVGJ 1YI2H 3CD6H 2PA2A 1QVGH 3DLLJ 2OTJH 1VQPH 2ZJQJ 3CCJH 4WFAJ 1NJIJ 1W2BH 3PIOJ 4UY8M 5GADN 5AN9F 1Q7YJ 1YJWH 1VQ6H 3G4SH 4IO9J 1YHQH 2QA4H 3CMAH 4WFNJ 4U67J 5DM7J 1VQLH 3OW2H 3CCVH 1M90J 4WF9J 3G6EH 2OTLH 1Y69K 4WFBJ 1VQMH 1VQKH 4IOAJ 1VQNH 1KD1J 3CCMH 1VQ9H 3CMEH 2ZJPJ 3CCSH 1QVFH 3CCLH 3CXCH 1S72H 3CCQH 5GAEN 1YIJH 1M1KJ 5JVHJ 3PIPJ 5GAGN 2QEXH 3CC4H 1K73J 3J7ZM 3CC2H 3I56H 4WCEJ 4IOCJ 3I55H 5MLCO 1N8RJ 3CCUH 1VQ4H 1VQOH 1WKIA 1K8AJ 3CCEH 1Q86J 5H1SO 1K9MJ 5DM6J 1VQ8H 1YJ9H 1KQSH 3CF5J 3G71H 1JJ2H 5HL7J 5GAHN 1VQ7H 2ZJRJ 1VQ5H
chains in the Genus database with same CATH superfamily
3CC7H 4GA4A 1VLBA 1KC8J 1FO4A 1QPNA 3WO1A 2W55B 3NVYC 1YITH 4YEKA 1Q82J 3SR6C 1AZYA 5HUPA 3CPWH 1O4UA 1N62B 3CCRH 3B9JC 1FFUB 1Q81J 3NS1C 2TPTA 3FAHA 1QPOA 4GA6A 1YJNH 1FM0E 5JVGJ 3L4PA 2JBMA 4USAA 1YI2H 2PA2A 3C2VA 1QVGH 3DLLJ 3CD6H 4C7YA 1NVJA 5EP8A 2OTJH 1OTPA 1NVIE 1N60B 1UOUA 2B7NA 2ZJQJ 1VQPH 3CCJH 4WFAJ 1NJIJ 4C7ZA 1W2BH 3PIOJ 4UY8M 3FC4A 5GADN 4I9AA 5HUOA 3C2RA 5AN9F 5AYYA 4US8A 2WP4A 1JRPB 4ZOHA 1DGJA 1Q7YJ 1YJWH 5EY3A 2ZJRJ 1VQ6H 1X1OA 2QIEA 3RPFA 3WO0A 1SIJA 3G4SH 4IO9J 1YHQH 2QA4H 3CMAH 1N61B 1ZXIB 5AYZA 4WFNJ 4U67J 3TQVA 1N5XA 2B7PA 3NRZC 3AMZA 2WK6A 2W3RB 5DM7J 1VQLH 1FMAE 2E3TA 1N63B 3OW2H 2J0FA 1QPQA 3PAJA 3CCVH 1M90J 4EAFA 4WF9J 3G6EH 1YTEA 2OTLH 2DSJA 3AN1A 4KWWA 4LHMA 4WFBJ 1Y69K 1VQMH 1VQKH 2B7QA 2Q5WE 4IOAJ 1VQNH 2OMDA 1KD1J 3GNNA 3C2OA 1N5WB 3CCMH 1VQ9H 1QPRA 3NVVC 3CMEH 2ZJPJ 4C80A 3CCSH 5HULA 4XR5A 1QVFH 3CCLH 3CXCH 1QAPA 1S72H 3CCQH 1YTDA 1WYGA 5MPOC 4KWVA 4X46A 5GAEN 3WNZA 1YIJH 2WK5A 3NVZC 1M1KJ 5JVHJ 4AP8A 2W3SB 3PIPJ 5GAGN 2QEXH 3CC4H 1K73J 3J7ZM 1YTKA 1BRWA 3CC2H 3I56H 4WCEJ 3L0GA 4IOCJ 3I55H 3C2EA 5MLCO 1N8RJ 3CCUH 1VQ4H 1JROB 2I14A 3ETRC 1VQOH 3C2FA 1WKIA 1K8AJ 3CCEH 1Q86J 5H1SO 1K9MJ 5DM6J 1VDVA 5AYXA 1SB3A 1VQ8H 1YJ9H 4YYYA 4US9A 1KQSH 3CF5J 4GA5A 1RM6A 2I1OA 4EADA 1FIQC 1FFVB 3H5QA 3G71H 1JJ2H 3BIIE 5HL7J 3EUB4 3VMMA 5GAHN 1VQ7H 3AM9A 2W54B 1V97A 1VQ5H 3NVWC
chains in the Genus database with same CATH topology
3CC7H 1KC8J 1YITH 1Q82J 3CPWH 3CCRH 1Q81J 1YJNH 5JVGJ 1YI2H 3CD6H 2PA2A 1QVGH 3DLLJ 2OTJH 1VQPH 2ZJQJ 3CCJH 4WFAJ 1NJIJ 1W2BH 3PIOJ 4UY8M 5GADN 5AN9F 1Q7YJ 1YJWH 1VQ6H 3G4SH 4IO9J 1YHQH 2QA4H 3CMAH 4WFNJ 4U67J 5DM7J 1VQLH 3OW2H 3CCVH 1M90J 4WF9J 3G6EH 2OTLH 1Y69K 4WFBJ 1VQMH 1VQKH 4IOAJ 1VQNH 1KD1J 3CCMH 1VQ9H 3CMEH 2ZJPJ 3CCSH 1QVFH 3CCLH 3CXCH 1S72H 3CCQH 5GAEN 1YIJH 1M1KJ 5JVHJ 3PIPJ 5GAGN 2QEXH 3CC4H 1K73J 3J7ZM 3CC2H 3I56H 4WCEJ 4IOCJ 3I55H 5MLCO 1N8RJ 3CCUH 1VQ4H 1VQOH 1WKIA 1K8AJ 3CCEH 1Q86J 5H1SO 1K9MJ 5DM6J 1VQ8H 1YJ9H 1KQSH 3CF5J 3G71H 1JJ2H 5HL7J 5GAHN 1VQ7H 2ZJRJ 1VQ5H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CC7 H;  1KC8 J;  1YIT H;  1Q82 J;  3CPW H;  3CCR H;  1Q81 J;  1YJN H;  5JVG J;  1YI2 H;  3CD6 H;  2PA2 A;  1QVG H;  3DLL J;  2OTJ H;  1VQP H;  2ZJQ J;  3CCJ H;  4WFA J;  1NJI J;  1W2B H;  3PIO J;  4UY8 M;  5GAD N;  5AN9 F;  1Q7Y J;  1YJW H;  1VQ6 H;  3G4S H;  4IO9 J;  1YHQ H;  2QA4 H;  3CMA H;  4WFN J;  4U67 J;  5DM7 J;  1VQL H;  3OW2 H;  3CCV H;  1M90 J;  4WF9 J;  3G6E H;  2OTL H;  1Y69 K;  4WFB J;  1VQM H;  1VQK H;  4IOA J;  1VQN H;  1KD1 J;  3CCM H;  1VQ9 H;  3CME H;  2ZJP J;  3CCS H;  1QVF H;  3CCL H;  3CXC H;  1S72 H;  3CCQ H;  5GAE N;  1YIJ H;  1M1K J;  5JVH J;  3PIP J;  5GAG N;  2QEX H;  3CC4 H;  1K73 J;  3J7Z M;  3CC2 H;  3I56 H;  4WCE J;  4IOC J;  3I55 H;  5MLC O;  1N8R J;  3CCU H;  1VQ4 H;  1VQO H;  1WKI A;  1K8A J;  3CCE H;  1Q86 J;  5H1S O;  1K9M J;  5DM6 J;  1VQ8 H;  1YJ9 H;  1KQS H;  3CF5 J;  3G71 H;  1JJ2 H;  5HL7 J;  5GAH N;  1VQ7 H;  2ZJR J;  1VQ5 H; 
#chains in the Genus database with same CATH topology
 3CC7 H;  4GA4 A;  1VLB A;  1KC8 J;  1FO4 A;  1QPN A;  3WO1 A;  2W55 B;  3NVY C;  1YIT H;  4YEK A;  1Q82 J;  3SR6 C;  1AZY A;  5HUP A;  3CPW H;  1O4U A;  1N62 B;  3CCR H;  3B9J C;  1FFU B;  1Q81 J;  3NS1 C;  2TPT A;  3FAH A;  1QPO A;  4GA6 A;  1YJN H;  1FM0 E;  5JVG J;  3L4P A;  2JBM A;  4USA A;  1YI2 H;  2PA2 A;  3C2V A;  1QVG H;  3DLL J;  3CD6 H;  4C7Y A;  1NVJ A;  5EP8 A;  2OTJ H;  1OTP A;  1NVI E;  1N60 B;  1UOU A;  2B7N A;  2ZJQ J;  1VQP H;  3CCJ H;  4WFA J;  1NJI J;  4C7Z A;  1W2B H;  3PIO J;  4UY8 M;  3FC4 A;  5GAD N;  4I9A A;  5HUO A;  3C2R A;  5AN9 F;  5AYY A;  4US8 A;  2WP4 A;  1JRP B;  4ZOH A;  1DGJ A;  1Q7Y J;  1YJW H;  5EY3 A;  2ZJR J;  1VQ6 H;  1X1O A;  2QIE A;  3RPF A;  3WO0 A;  1SIJ A;  3G4S H;  4IO9 J;  1YHQ H;  2QA4 H;  3CMA H;  1N61 B;  1ZXI B;  5AYZ A;  4WFN J;  4U67 J;  3TQV A;  1N5X A;  2B7P A;  3NRZ C;  3AMZ A;  2WK6 A;  2W3R B;  5DM7 J;  1VQL H;  1FMA E;  2E3T A;  1N63 B;  3OW2 H;  2J0F A;  1QPQ A;  3PAJ A;  3CCV H;  1M90 J;  4EAF A;  4WF9 J;  3G6E H;  1YTE A;  2OTL H;  2DSJ A;  3AN1 A;  4KWW A;  4LHM A;  4WFB J;  1Y69 K;  1VQM H;  1VQK H;  2B7Q A;  2Q5W E;  4IOA J;  1VQN H;  2OMD A;  1KD1 J;  3GNN A;  3C2O A;  1N5W B;  3CCM H;  1VQ9 H;  1QPR A;  3NVV C;  3CME H;  2ZJP J;  4C80 A;  3CCS H;  5HUL A;  4XR5 A;  1QVF H;  3CCL H;  3CXC H;  1QAP A;  1S72 H;  3CCQ H;  1YTD A;  1WYG A;  5MPO C;  4KWV A;  4X46 A;  5GAE N;  3WNZ A;  1YIJ H;  2WK5 A;  3NVZ C;  1M1K J;  5JVH J;  4AP8 A;  2W3S B;  3PIP J;  5GAG N;  2QEX H;  3CC4 H;  1K73 J;  3J7Z M;  1YTK A;  1BRW A;  3CC2 H;  3I56 H;  4WCE J;  3L0G A;  4IOC J;  3I55 H;  3C2E A;  5MLC O;  1N8R J;  3CCU H;  1VQ4 H;  1JRO B;  2I14 A;  3ETR C;  1VQO H;  3C2F A;  1WKI A;  1K8A J;  3CCE H;  1Q86 J;  5H1S O;  1K9M J;  5DM6 J;  1VDV A;  5AYX A;  1SB3 A;  1VQ8 H;  1YJ9 H;  4YYY A;  4US9 A;  1KQS H;  3CF5 J;  4GA5 A;  1RM6 A;  2I1O A;  4EAD A;  1FIQ C;  1FFV B;  3H5Q A;  3G71 H;  1JJ2 H;  3BII E;  5HL7 J;  3EUB 4;  3VMM A;  5GAH N;  1VQ7 H;  3AM9 A;  2W54 B;  1V97 A;  1VQ5 H;  3NVW C; 
#chains in the Genus database with same CATH homology
 3CC7 H;  1KC8 J;  1YIT H;  1Q82 J;  3CPW H;  3CCR H;  1Q81 J;  1YJN H;  5JVG J;  1YI2 H;  3CD6 H;  2PA2 A;  1QVG H;  3DLL J;  2OTJ H;  1VQP H;  2ZJQ J;  3CCJ H;  4WFA J;  1NJI J;  1W2B H;  3PIO J;  4UY8 M;  5GAD N;  5AN9 F;  1Q7Y J;  1YJW H;  1VQ6 H;  3G4S H;  4IO9 J;  1YHQ H;  2QA4 H;  3CMA H;  4WFN J;  4U67 J;  5DM7 J;  1VQL H;  3OW2 H;  3CCV H;  1M90 J;  4WF9 J;  3G6E H;  2OTL H;  1Y69 K;  4WFB J;  1VQM H;  1VQK H;  4IOA J;  1VQN H;  1KD1 J;  3CCM H;  1VQ9 H;  3CME H;  2ZJP J;  3CCS H;  1QVF H;  3CCL H;  3CXC H;  1S72 H;  3CCQ H;  5GAE N;  1YIJ H;  1M1K J;  5JVH J;  3PIP J;  5GAG N;  2QEX H;  3CC4 H;  1K73 J;  3J7Z M;  3CC2 H;  3I56 H;  4WCE J;  4IOC J;  3I55 H;  5MLC O;  1N8R J;  3CCU H;  1VQ4 H;  1VQO H;  1WKI A;  1K8A J;  3CCE H;  1Q86 J;  5H1S O;  1K9M J;  5DM6 J;  1VQ8 H;  1YJ9 H;  1KQS H;  3CF5 J;  3G71 H;  1JJ2 H;  5HL7 J;  5GAH N;  1VQ7 H;  2ZJR J;  1VQ5 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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