1YI2H

Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 39
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2005-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1yi2H00
3CPWH 3CCLH 1VQNH 4IO9J 1N8RJ 1YHQH 5GAHN 1K73J 4UY8M 5JVGJ 1M1KJ 1KC8J 4IOCJ 1QVGH 1K9MJ 5DM6J 5DM7J 5JVHJ 1YJWH 1Q86J 3PIPJ 3CCQH 3OW2H 3CC2H 3CCMH 3PIOJ 1KD1J 1VQPH 3G71H 5MLCO 1Q7YJ 5AN9F 5GADN 3I55H 3CCJH 3CC7H 3CMEH 3I56H 1Y69K 1W2BH 1QVFH 4IOAJ 1WKIA 1VQKH 3CXCH 4U67J 1VQOH 3CCSH 1NJIJ 3J7ZM 2OTLH 2ZJPJ 1YITH 1M90J 1Q82J 4WFNJ 2ZJRJ 3DLLJ 1JJ2H 5HL7J 1YIJH 1YJNH 4WF9J 3CF5J 1VQLH 3G6EH 3CD6H 3CCUH 1K8AJ 1VQ9H 3CCVH 3CMAH 4WFAJ 2OTJH 3CC4H 1VQ7H 1KQSH 1VQ8H 4WCEJ 3G4SH 2QA4H 1YJ9H 1VQ4H 5GAEN 3CCEH 1VQMH 2PA2A 1VQ5H 1Q81J 5GAGN 2QEXH 4WFBJ 2ZJQJ 3CCRH 1YI2H 1S72H 1VQ6H 5H1SO
chains in the Genus database with same CATH superfamily
1YTEA 4XR5A 3CCLH 3CPWH 1VQNH 4IO9J 1N8RJ 4YYYA 3WO0A 5MPOC 1NVIE 1YHQH 3NS1C 1QPRA 5GAHN 1K73J 2W3SB 4UY8M 5JVGJ 1KC8J 1M1KJ 1YTDA 3BIIE 3AMZA 4IOCJ 1QVGH 3H5QA 1K9MJ 5DM7J 5DM6J 2I14A 5JVHJ 3WNZA 4EADA 1YJWH 2W54B 1SB3A 3NVWC 1Q86J 3PIPJ 3CCQH 2QIEA 1QPQA 4C7YA 1FIQC 3C2OA 3OW2H 1N5XA 3CC2H 3CCMH 3PIOJ 2OMDA 1KD1J 1VDVA 4X46A 3G71H 5MLCO 3NVYC 1VQPH 1JROB 3NVVC 4USAA 1Q7YJ 5AN9F 5GADN 1FM0E 3FC4A 3I55H 3CCJH 1N62B 3CC7H 4GA6A 3CMEH 3L4PA 1YTKA 4I9AA 3I56H 1Y69K 1W2BH 1QVFH 2E3TA 4IOAJ 1FFUB 1WKIA 4C7ZA 1RM6A 1X1OA 4US8A 3PAJA 1VQKH 4EAFA 3CXCH 4U67J 4KWVA 1N61B 2JBMA 3FAHA 1VQOH 4AP8A 1DGJA 2Q5WE 3CCSH 1NJIJ 1QPOA 3J7ZM 5HUPA 2OTLH 1VLBA 1N5WB 2ZJPJ 1FMAE 3B9JC 1O4UA 4LHMA 1YITH 3EUB4 1Q82J 4GA4A 2J0FA 1M90J 2WK5A 5EY3A 4WFNJ 5EP8A 2ZJRJ 3SR6C 3DLLJ 1QAPA 1QPNA 2W55B 1JJ2H 5HL7J 1YIJH 1YJNH 4WF9J 3CF5J 1VQLH 3G6EH 5AYXA 3CD6H 3C2FA 3CCUH 4C80A 1K8AJ 3NVZC 1ZXIB 5AYZA 1VQ9H 3AM9A 3AN1A 3CCVH 3CMAH 2WP4A 4WFAJ 2B7QA 2I1OA 3C2EA 5HUOA 1SIJA 4YEKA 3L0GA 3ETRC 5HULA 1N60B 1UOUA 3NRZC 3CC4H 1KQSH 1VQ8H 2B7NA 1VQ7H 2OTJH 4ZOHA 3GNNA 4WCEJ 3G4SH 2QA4H 1YJ9H 1N63B 1VQ4H 5GAEN 1OTPA 1V97A 3CCEH 1WYGA 5AYYA 2PA2A 4US9A 1VQMH 1AZYA 1VQ5H 1NVJA 2WK6A 4KWWA 1Q81J 3TQVA 3WO1A 3RPFA 5GAGN 2QEXH 3C2RA 1BRWA 1JRPB 4WFBJ 2ZJQJ 3CCRH 1YI2H 1S72H 2B7PA 1FO4A 2TPTA 2DSJA 1VQ6H 2W3RB 3C2VA 3VMMA 1FFVB 5H1SO 4GA5A
chains in the Genus database with same CATH topology
3CPWH 3CCLH 1VQNH 4IO9J 1N8RJ 1YHQH 5GAHN 1K73J 4UY8M 5JVGJ 1M1KJ 1KC8J 4IOCJ 1QVGH 1K9MJ 5DM6J 5DM7J 5JVHJ 1YJWH 1Q86J 3PIPJ 3CCQH 3OW2H 3CC2H 3CCMH 3PIOJ 1KD1J 1VQPH 3G71H 5MLCO 1Q7YJ 5AN9F 5GADN 3I55H 3CCJH 3CC7H 3CMEH 3I56H 1Y69K 1W2BH 1QVFH 4IOAJ 1WKIA 1VQKH 3CXCH 4U67J 1VQOH 3CCSH 1NJIJ 3J7ZM 2OTLH 2ZJPJ 1YITH 1M90J 1Q82J 4WFNJ 2ZJRJ 3DLLJ 1JJ2H 5HL7J 1YIJH 1YJNH 4WF9J 3CF5J 1VQLH 3G6EH 3CD6H 3CCUH 1K8AJ 1VQ9H 3CCVH 3CMAH 4WFAJ 2OTJH 3CC4H 1VQ7H 1KQSH 1VQ8H 4WCEJ 3G4SH 2QA4H 1YJ9H 1VQ4H 5GAEN 3CCEH 1VQMH 2PA2A 1VQ5H 1Q81J 5GAGN 2QEXH 4WFBJ 2ZJQJ 3CCRH 1YI2H 1S72H 1VQ6H 5H1SO
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CPW H;  3CCL H;  1VQN H;  4IO9 J;  1N8R J;  1YHQ H;  5GAH N;  1K73 J;  4UY8 M;  5JVG J;  1M1K J;  1KC8 J;  4IOC J;  1QVG H;  1K9M J;  5DM6 J;  5DM7 J;  5JVH J;  1YJW H;  1Q86 J;  3PIP J;  3CCQ H;  3OW2 H;  3CC2 H;  3CCM H;  3PIO J;  1KD1 J;  1VQP H;  3G71 H;  5MLC O;  1Q7Y J;  5AN9 F;  5GAD N;  3I55 H;  3CCJ H;  3CC7 H;  3CME H;  3I56 H;  1Y69 K;  1W2B H;  1QVF H;  4IOA J;  1WKI A;  1VQK H;  3CXC H;  4U67 J;  1VQO H;  3CCS H;  1NJI J;  3J7Z M;  2OTL H;  2ZJP J;  1YIT H;  1M90 J;  1Q82 J;  4WFN J;  2ZJR J;  3DLL J;  1JJ2 H;  5HL7 J;  1YIJ H;  1YJN H;  4WF9 J;  3CF5 J;  1VQL H;  3G6E H;  3CD6 H;  3CCU H;  1K8A J;  1VQ9 H;  3CCV H;  3CMA H;  4WFA J;  2OTJ H;  3CC4 H;  1VQ7 H;  1KQS H;  1VQ8 H;  4WCE J;  3G4S H;  2QA4 H;  1YJ9 H;  1VQ4 H;  5GAE N;  3CCE H;  1VQM H;  2PA2 A;  1VQ5 H;  1Q81 J;  5GAG N;  2QEX H;  4WFB J;  2ZJQ J;  3CCR H;  1YI2 H;  1S72 H;  1VQ6 H;  5H1S O; 
#chains in the Genus database with same CATH topology
 1YTE A;  4XR5 A;  3CCL H;  3CPW H;  1VQN H;  4IO9 J;  1N8R J;  4YYY A;  3WO0 A;  5MPO C;  1NVI E;  1YHQ H;  3NS1 C;  1QPR A;  5GAH N;  1K73 J;  2W3S B;  4UY8 M;  5JVG J;  1KC8 J;  1M1K J;  1YTD A;  3BII E;  3AMZ A;  4IOC J;  1QVG H;  3H5Q A;  1K9M J;  5DM7 J;  5DM6 J;  2I14 A;  5JVH J;  3WNZ A;  4EAD A;  1YJW H;  2W54 B;  1SB3 A;  3NVW C;  1Q86 J;  3PIP J;  3CCQ H;  2QIE A;  1QPQ A;  4C7Y A;  1FIQ C;  3C2O A;  3OW2 H;  1N5X A;  3CC2 H;  3CCM H;  3PIO J;  2OMD A;  1KD1 J;  1VDV A;  4X46 A;  3G71 H;  5MLC O;  3NVY C;  1VQP H;  1JRO B;  3NVV C;  4USA A;  1Q7Y J;  5AN9 F;  5GAD N;  1FM0 E;  3FC4 A;  3I55 H;  3CCJ H;  1N62 B;  3CC7 H;  4GA6 A;  3CME H;  3L4P A;  1YTK A;  4I9A A;  3I56 H;  1Y69 K;  1W2B H;  1QVF H;  2E3T A;  4IOA J;  1FFU B;  1WKI A;  4C7Z A;  1RM6 A;  1X1O A;  4US8 A;  3PAJ A;  1VQK H;  4EAF A;  3CXC H;  4U67 J;  4KWV A;  1N61 B;  2JBM A;  3FAH A;  1VQO H;  4AP8 A;  1DGJ A;  2Q5W E;  3CCS H;  1NJI J;  1QPO A;  3J7Z M;  5HUP A;  2OTL H;  1VLB A;  1N5W B;  2ZJP J;  1FMA E;  3B9J C;  1O4U A;  4LHM A;  1YIT H;  3EUB 4;  1Q82 J;  4GA4 A;  2J0F A;  1M90 J;  2WK5 A;  5EY3 A;  4WFN J;  5EP8 A;  2ZJR J;  3SR6 C;  3DLL J;  1QAP A;  1QPN A;  2W55 B;  1JJ2 H;  5HL7 J;  1YIJ H;  1YJN H;  4WF9 J;  3CF5 J;  1VQL H;  3G6E H;  5AYX A;  3CD6 H;  3C2F A;  3CCU H;  4C80 A;  1K8A J;  3NVZ C;  1ZXI B;  5AYZ A;  1VQ9 H;  3AM9 A;  3AN1 A;  3CCV H;  3CMA H;  2WP4 A;  4WFA J;  2B7Q A;  2I1O A;  3C2E A;  5HUO A;  1SIJ A;  4YEK A;  3L0G A;  3ETR C;  5HUL A;  1N60 B;  1UOU A;  3NRZ C;  3CC4 H;  1KQS H;  1VQ8 H;  2B7N A;  1VQ7 H;  2OTJ H;  4ZOH A;  3GNN A;  4WCE J;  3G4S H;  2QA4 H;  1YJ9 H;  1N63 B;  1VQ4 H;  5GAE N;  1OTP A;  1V97 A;  3CCE H;  1WYG A;  5AYY A;  2PA2 A;  4US9 A;  1VQM H;  1AZY A;  1VQ5 H;  1NVJ A;  2WK6 A;  4KWW A;  1Q81 J;  3TQV A;  3WO1 A;  3RPF A;  5GAG N;  2QEX H;  3C2R A;  1BRW A;  1JRP B;  4WFB J;  2ZJQ J;  3CCR H;  1YI2 H;  1S72 H;  2B7P A;  1FO4 A;  2TPT A;  2DSJ A;  1VQ6 H;  2W3R B;  3C2V A;  3VMM A;  1FFV B;  5H1S O;  4GA5 A; 
#chains in the Genus database with same CATH homology
 3CPW H;  3CCL H;  1VQN H;  4IO9 J;  1N8R J;  1YHQ H;  5GAH N;  1K73 J;  4UY8 M;  5JVG J;  1M1K J;  1KC8 J;  4IOC J;  1QVG H;  1K9M J;  5DM6 J;  5DM7 J;  5JVH J;  1YJW H;  1Q86 J;  3PIP J;  3CCQ H;  3OW2 H;  3CC2 H;  3CCM H;  3PIO J;  1KD1 J;  1VQP H;  3G71 H;  5MLC O;  1Q7Y J;  5AN9 F;  5GAD N;  3I55 H;  3CCJ H;  3CC7 H;  3CME H;  3I56 H;  1Y69 K;  1W2B H;  1QVF H;  4IOA J;  1WKI A;  1VQK H;  3CXC H;  4U67 J;  1VQO H;  3CCS H;  1NJI J;  3J7Z M;  2OTL H;  2ZJP J;  1YIT H;  1M90 J;  1Q82 J;  4WFN J;  2ZJR J;  3DLL J;  1JJ2 H;  5HL7 J;  1YIJ H;  1YJN H;  4WF9 J;  3CF5 J;  1VQL H;  3G6E H;  3CD6 H;  3CCU H;  1K8A J;  1VQ9 H;  3CCV H;  3CMA H;  4WFA J;  2OTJ H;  3CC4 H;  1VQ7 H;  1KQS H;  1VQ8 H;  4WCE J;  3G4S H;  2QA4 H;  1YJ9 H;  1VQ4 H;  5GAE N;  3CCE H;  1VQM H;  2PA2 A;  1VQ5 H;  1Q81 J;  5GAG N;  2QEX H;  4WFB J;  2ZJQ J;  3CCR H;  1YI2 H;  1S72 H;  1VQ6 H;  5H1S O; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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