1YIJH

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 39
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1yijH00
4IOCJ 1YITH 3CCRH 1KQSH 3CCEH 1W2BH 1YJNH 3PIOJ 1YJWH 5GAEN 5AN9F 2OTLH 1VQKH 1QVGH 3G6EH 1Q81J 1K9MJ 3DLLJ 4IO9J 4WFNJ 1M1KJ 1VQ7H 1VQ9H 1VQ5H 5MLCO 4WFBJ 3CCSH 1VQLH 3I56H 1Q82J 3CC7H 3CCMH 1YIJH 1K8AJ 3CC4H 3CCUH 5HL7J 5GAGN 5DM6J 3J7ZM 3CMEH 1Y69K 3CXCH 1YHQH 1KC8J 3OW2H 4UY8M 1YJ9H 1VQOH 3I55H 3CCVH 1QVFH 3CPWH 2PA2A 3G4SH 2QA4H 3CCLH 1VQ8H 5DM7J 1K73J 3CF5J 3CCQH 4WF9J 1Q86J 1N8RJ 2ZJPJ 2ZJRJ 3PIPJ 5H1SO 1VQPH 2OTJH 2ZJQJ 1M90J 3G71H 4WFAJ 1VQ4H 5JVHJ 4U67J 5GADN 1JJ2H 4WCEJ 1KD1J 3CMAH 5GAHN 1VQMH 3CC2H 1NJIJ 1WKIA 1VQ6H 4IOAJ 1VQNH 5JVGJ 3CCJH 1S72H 3CD6H 2QEXH 1YI2H 1Q7YJ
chains in the Genus database with same CATH superfamily
4YEKA 4IOCJ 1DGJA 1YITH 3NVZC 5AYYA 1N62B 3CCRH 5HUPA 2I14A 1KQSH 2B7NA 3CCEH 1QPRA 1QPOA 3NVVC 1QPQA 1W2BH 1YJNH 3PIOJ 4ZOHA 2QIEA 1YJWH 3C2EA 3NVYC 1N5WB 2WK5A 1FFVB 5GAEN 5AN9F 3L0GA 3NS1C 3C2OA 2OTLH 1YTDA 1VQKH 4C7ZA 3G6EH 1QVGH 1Q81J 4GA4A 1FM0E 1K9MJ 3DLLJ 1VDVA 3C2RA 1AZYA 5EP8A 1JRPB 4IO9J 4GA6A 3WNZA 1N61B 4WFNJ 1M1KJ 1VQ9H 1VQ7H 1VQ5H 5MLCO 4WFBJ 3CCSH 1FMAE 1O4UA 1OTPA 1QPNA 2B7PA 2B7QA 4USAA 5HUOA 4C80A 3I56H 1Q82J 2JBMA 1VQLH 3CCMH 3CC7H 3VMMA 3FC4A 1YIJH 1K8AJ 2W3SB 2TPTA 5EY3A 3GNNA 4X46A 3CC4H 3CCUH 3B9JC 5HL7J 1YTKA 5GAGN 1QAPA 5DM6J 3J7ZM 3TQVA 1SB3A 1FFUB 3CMEH 4LHMA 1Y69K 4C7YA 3CXCH 1YHQH 1KC8J 1VLBA 3OW2H 2W3RB 5AYZA 1YJ9H 2J0FA 3I55H 1VQOH 3CCVH 1FO4A 4UY8M 1QVFH 3CPWH 2DSJA 2W55B 3H5QA 3SR6C 2PA2A 3G4SH 3EUB4 3AM9A 4US8A 1NVIE 5MPOC 3NRZC 4I9AA 3AMZA 5HULA 1WYGA 2QA4H 3CCLH 1BRWA 1SIJA 2E3TA 2OMDA 1VQ8H 5DM7J 1FIQC 2I1OA 4AP8A 3CCQH 3CF5J 1K73J 4WF9J 2Q5WE 1Q86J 3NVWC 4EAFA 2ZJPJ 1N8RJ 2ZJRJ 3PIPJ 5H1SO 1VQPH 2OTJH 1RM6A 2ZJQJ 3PAJA 4KWVA 3G71H 3WO1A 4WFAJ 1M90J 3C2FA 4XR5A 1UOUA 1VQ4H 3C2VA 3WO0A 3AN1A 5JVHJ 4U67J 1ZXIB 3BIIE 5GADN 1JJ2H 4US9A 4WCEJ 2WK6A 1KD1J 3CMAH 1N60B 2W54B 5GAHN 1VQMH 3CC2H 1NVJA 5AYXA 4YYYA 3RPFA 1X1OA 1NJIJ 1WKIA 1V97A 1YTEA 1VQ6H 4IOAJ 3ETRC 4GA5A 1VQNH 1N63B 5JVGJ 3CCJH 4KWWA 4EADA 2WP4A 3FAHA 3L4PA 1S72H 3CD6H 2QEXH 1N5XA 1YI2H 1Q7YJ 1JROB
chains in the Genus database with same CATH topology
4IOCJ 1YITH 3CCRH 1KQSH 3CCEH 1W2BH 1YJNH 3PIOJ 1YJWH 5GAEN 5AN9F 2OTLH 1VQKH 1QVGH 3G6EH 1Q81J 1K9MJ 3DLLJ 4IO9J 4WFNJ 1M1KJ 1VQ7H 1VQ9H 1VQ5H 5MLCO 4WFBJ 3CCSH 1VQLH 3I56H 1Q82J 3CC7H 3CCMH 1YIJH 1K8AJ 3CC4H 3CCUH 5HL7J 5GAGN 5DM6J 3J7ZM 3CMEH 1Y69K 3CXCH 1YHQH 1KC8J 3OW2H 4UY8M 1YJ9H 1VQOH 3I55H 3CCVH 1QVFH 3CPWH 2PA2A 3G4SH 2QA4H 3CCLH 1VQ8H 5DM7J 1K73J 3CF5J 3CCQH 4WF9J 1Q86J 1N8RJ 2ZJPJ 2ZJRJ 3PIPJ 5H1SO 1VQPH 2OTJH 2ZJQJ 1M90J 3G71H 4WFAJ 1VQ4H 5JVHJ 4U67J 5GADN 1JJ2H 4WCEJ 1KD1J 3CMAH 5GAHN 1VQMH 3CC2H 1NJIJ 1WKIA 1VQ6H 4IOAJ 1VQNH 5JVGJ 3CCJH 1S72H 3CD6H 2QEXH 1YI2H 1Q7YJ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IOC J;  1YIT H;  3CCR H;  1KQS H;  3CCE H;  1W2B H;  1YJN H;  3PIO J;  1YJW H;  5GAE N;  5AN9 F;  2OTL H;  1VQK H;  1QVG H;  3G6E H;  1Q81 J;  1K9M J;  3DLL J;  4IO9 J;  4WFN J;  1M1K J;  1VQ7 H;  1VQ9 H;  1VQ5 H;  5MLC O;  4WFB J;  3CCS H;  1VQL H;  3I56 H;  1Q82 J;  3CC7 H;  3CCM H;  1YIJ H;  1K8A J;  3CC4 H;  3CCU H;  5HL7 J;  5GAG N;  5DM6 J;  3J7Z M;  3CME H;  1Y69 K;  3CXC H;  1YHQ H;  1KC8 J;  3OW2 H;  4UY8 M;  1YJ9 H;  1VQO H;  3I55 H;  3CCV H;  1QVF H;  3CPW H;  2PA2 A;  3G4S H;  2QA4 H;  3CCL H;  1VQ8 H;  5DM7 J;  1K73 J;  3CF5 J;  3CCQ H;  4WF9 J;  1Q86 J;  1N8R J;  2ZJP J;  2ZJR J;  3PIP J;  5H1S O;  1VQP H;  2OTJ H;  2ZJQ J;  1M90 J;  3G71 H;  4WFA J;  1VQ4 H;  5JVH J;  4U67 J;  5GAD N;  1JJ2 H;  4WCE J;  1KD1 J;  3CMA H;  5GAH N;  1VQM H;  3CC2 H;  1NJI J;  1WKI A;  1VQ6 H;  4IOA J;  1VQN H;  5JVG J;  3CCJ H;  1S72 H;  3CD6 H;  2QEX H;  1YI2 H;  1Q7Y J; 
#chains in the Genus database with same CATH topology
 4YEK A;  4IOC J;  1DGJ A;  1YIT H;  3NVZ C;  5AYY A;  1N62 B;  3CCR H;  5HUP A;  2I14 A;  1KQS H;  2B7N A;  3CCE H;  1QPR A;  1QPO A;  3NVV C;  1QPQ A;  1W2B H;  1YJN H;  3PIO J;  4ZOH A;  2QIE A;  1YJW H;  3C2E A;  3NVY C;  1N5W B;  2WK5 A;  1FFV B;  5GAE N;  5AN9 F;  3L0G A;  3NS1 C;  3C2O A;  2OTL H;  1YTD A;  1VQK H;  4C7Z A;  3G6E H;  1QVG H;  1Q81 J;  4GA4 A;  1FM0 E;  1K9M J;  3DLL J;  1VDV A;  3C2R A;  1AZY A;  5EP8 A;  1JRP B;  4IO9 J;  4GA6 A;  3WNZ A;  1N61 B;  4WFN J;  1M1K J;  1VQ9 H;  1VQ7 H;  1VQ5 H;  5MLC O;  4WFB J;  3CCS H;  1FMA E;  1O4U A;  1OTP A;  1QPN A;  2B7P A;  2B7Q A;  4USA A;  5HUO A;  4C80 A;  3I56 H;  1Q82 J;  2JBM A;  1VQL H;  3CCM H;  3CC7 H;  3VMM A;  3FC4 A;  1YIJ H;  1K8A J;  2W3S B;  2TPT A;  5EY3 A;  3GNN A;  4X46 A;  3CC4 H;  3CCU H;  3B9J C;  5HL7 J;  1YTK A;  5GAG N;  1QAP A;  5DM6 J;  3J7Z M;  3TQV A;  1SB3 A;  1FFU B;  3CME H;  4LHM A;  1Y69 K;  4C7Y A;  3CXC H;  1YHQ H;  1KC8 J;  1VLB A;  3OW2 H;  2W3R B;  5AYZ A;  1YJ9 H;  2J0F A;  3I55 H;  1VQO H;  3CCV H;  1FO4 A;  4UY8 M;  1QVF H;  3CPW H;  2DSJ A;  2W55 B;  3H5Q A;  3SR6 C;  2PA2 A;  3G4S H;  3EUB 4;  3AM9 A;  4US8 A;  1NVI E;  5MPO C;  3NRZ C;  4I9A A;  3AMZ A;  5HUL A;  1WYG A;  2QA4 H;  3CCL H;  1BRW A;  1SIJ A;  2E3T A;  2OMD A;  1VQ8 H;  5DM7 J;  1FIQ C;  2I1O A;  4AP8 A;  3CCQ H;  3CF5 J;  1K73 J;  4WF9 J;  2Q5W E;  1Q86 J;  3NVW C;  4EAF A;  2ZJP J;  1N8R J;  2ZJR J;  3PIP J;  5H1S O;  1VQP H;  2OTJ H;  1RM6 A;  2ZJQ J;  3PAJ A;  4KWV A;  3G71 H;  3WO1 A;  4WFA J;  1M90 J;  3C2F A;  4XR5 A;  1UOU A;  1VQ4 H;  3C2V A;  3WO0 A;  3AN1 A;  5JVH J;  4U67 J;  1ZXI B;  3BII E;  5GAD N;  1JJ2 H;  4US9 A;  4WCE J;  2WK6 A;  1KD1 J;  3CMA H;  1N60 B;  2W54 B;  5GAH N;  1VQM H;  3CC2 H;  1NVJ A;  5AYX A;  4YYY A;  3RPF A;  1X1O A;  1NJI J;  1WKI A;  1V97 A;  1YTE A;  1VQ6 H;  4IOA J;  3ETR C;  4GA5 A;  1VQN H;  1N63 B;  5JVG J;  3CCJ H;  4KWW A;  4EAD A;  2WP4 A;  3FAH A;  3L4P A;  1S72 H;  3CD6 H;  2QEX H;  1N5X A;  1YI2 H;  1Q7Y J;  1JRO B; 
#chains in the Genus database with same CATH homology
 4IOC J;  1YIT H;  3CCR H;  1KQS H;  3CCE H;  1W2B H;  1YJN H;  3PIO J;  1YJW H;  5GAE N;  5AN9 F;  2OTL H;  1VQK H;  1QVG H;  3G6E H;  1Q81 J;  1K9M J;  3DLL J;  4IO9 J;  4WFN J;  1M1K J;  1VQ7 H;  1VQ9 H;  1VQ5 H;  5MLC O;  4WFB J;  3CCS H;  1VQL H;  3I56 H;  1Q82 J;  3CC7 H;  3CCM H;  1YIJ H;  1K8A J;  3CC4 H;  3CCU H;  5HL7 J;  5GAG N;  5DM6 J;  3J7Z M;  3CME H;  1Y69 K;  3CXC H;  1YHQ H;  1KC8 J;  3OW2 H;  4UY8 M;  1YJ9 H;  1VQO H;  3I55 H;  3CCV H;  1QVF H;  3CPW H;  2PA2 A;  3G4S H;  2QA4 H;  3CCL H;  1VQ8 H;  5DM7 J;  1K73 J;  3CF5 J;  3CCQ H;  4WF9 J;  1Q86 J;  1N8R J;  2ZJP J;  2ZJR J;  3PIP J;  5H1S O;  1VQP H;  2OTJ H;  2ZJQ J;  1M90 J;  3G71 H;  4WFA J;  1VQ4 H;  5JVH J;  4U67 J;  5GAD N;  1JJ2 H;  4WCE J;  1KD1 J;  3CMA H;  5GAH N;  1VQM H;  3CC2 H;  1NJI J;  1WKI A;  1VQ6 H;  4IOA J;  1VQN H;  5JVG J;  3CCJ H;  1S72 H;  3CD6 H;  2QEX H;  1YI2 H;  1Q7Y J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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