1YIJH

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 39
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1yijH00
4IO9J 1K8AJ 3G71H 3I56H 1VQ9H 4UY8M 3CCUH 1QVGH 3CCSH 1YJWH 2QEXH 1W2BH 1Q81J 3CCEH 5AN9F 1WKIA 1VQMH 1Q7YJ 1VQ5H 5GAEN 3CMEH 4WF9J 1KD1J 1YI2H 3CCLH 3CCJH 1NJIJ 5GAHN 3CXCH 1K73J 3PIPJ 1Q86J 1YJ9H 1VQ7H 1VQOH 5DM7J 3OW2H 5HL7J 1VQPH 3J7ZM 2ZJRJ 3PIOJ 3CC4H 2QA4H 5JVHJ 2OTJH 1QVFH 1KC8J 3CCRH 1K9MJ 1VQ6H 1VQ4H 1VQKH 3DLLJ 4IOAJ 4WFBJ 5JVGJ 5MLCO 2ZJPJ 1N8RJ 1YJNH 2ZJQJ 1YIJH 3CPWH 3I55H 3CC7H 1YITH 1JJ2H 1Y69K 3G4SH 1Q82J 1VQLH 4WFNJ 4WCEJ 5DM6J 3CMAH 5GAGN 1S72H 4WFAJ 3CCMH 3CCQH 3CC2H 1VQNH 1M1KJ 3CCVH 3CD6H 1VQ8H 2PA2A 4U67J 3G6EH 3CF5J 1M90J 4IOCJ 5H1SO 5GADN 1KQSH 2OTLH 1YHQH
chains in the Genus database with same CATH superfamily
4IO9J 1QPOA 4GA6A 1K8AJ 1YTEA 3G71H 2I1OA 3C2VA 3I56H 1VQ9H 4UY8M 1DGJA 3CCUH 1QVGH 3CCSH 1YJWH 1N5XA 2QEXH 1W2BH 1Q81J 5HUOA 2WP4A 3CCEH 1ZXIB 1OTPA 1NVJA 2W54B 4GA4A 5AN9F 1BRWA 1WKIA 4X46A 3RPFA 3SR6C 3ETRC 2E3TA 4EAFA 3NVYC 1VQMH 3WNZA 1Q7YJ 1VQ5H 3FAHA 1UOUA 4EADA 5GAEN 1FFUB 2W3RB 1VDVA 3CMEH 4WF9J 3NVZC 3CCLH 1YI2H 1KD1J 3CCJH 2B7QA 1NJIJ 1SIJA 4USAA 3FC4A 5EP8A 5AYZA 5GAHN 2B7PA 5AYYA 3CXCH 3L0GA 1K73J 3PIPJ 2WK6A 1Q86J 4C7ZA 3NVWC 1YJ9H 5AYXA 1VQOH 1VQ7H 2OTLH 5DM7J 3OW2H 5HL7J 1VQPH 5MPOC 1QPQA 3J7ZM 2ZJRJ 2WK5A 3PIOJ 3CC4H 2QA4H 5JVHJ 1V97A 2OTJH 3B9JC 3WO0A 1JRPB 4AP8A 1QVFH 1KC8J 3CCRH 1FMAE 1K9MJ 4GA5A 1VQ6H 1YTDA 1N60B 1VQ4H 4US8A 1NVIE 3AN1A 1VQKH 2OMDA 3DLLJ 1FM0E 3NS1C 1N63B 3NVVC 4XR5A 4IOAJ 2W3SB 4KWWA 2B7NA 4WFBJ 5JVGJ 3AMZA 2I14A 2W55B 5MLCO 5EY3A 1N5WB 5HULA 2ZJPJ 1N8RJ 3C2RA 4US9A 3VMMA 1QAPA 1JROB 1YJNH 3TQVA 2ZJQJ 4I9AA 1YIJH 3C2OA 2DSJA 2J0FA 3GNNA 3CPWH 3I55H 3C2FA 3CC7H 3BIIE 1RM6A 1YITH 1JJ2H 1FO4A 1Y69K 1AZYA 2Q5WE 3G4SH 1Q82J 1VQLH 3NRZC 2JBMA 4WFNJ 1SB3A 4KWVA 5DM6J 1N61B 1QPNA 3WO1A 4WCEJ 1FIQC 3CMAH 4ZOHA 1VLBA 5GAGN 3EUB4 1S72H 4WFAJ 1FFVB 3CCMH 3H5QA 1O4UA 5HUPA 3CCQH 1N62B 1WYGA 3C2EA 3CC2H 1X1OA 1VQNH 1M1KJ 3CCVH 3CD6H 4LHMA 4YEKA 3PAJA 2QIEA 1VQ8H 2PA2A 4U67J 3AM9A 3G6EH 3CF5J 1M90J 4C80A 4IOCJ 4YYYA 5H1SO 1YTKA 1QPRA 5GADN 1KQSH 3L4PA 2TPTA 1YHQH 4C7YA
chains in the Genus database with same CATH topology
4IO9J 1K8AJ 3G71H 3I56H 1VQ9H 4UY8M 3CCUH 1QVGH 3CCSH 1YJWH 2QEXH 1W2BH 1Q81J 3CCEH 5AN9F 1WKIA 1VQMH 1Q7YJ 1VQ5H 5GAEN 3CMEH 4WF9J 1KD1J 1YI2H 3CCLH 3CCJH 1NJIJ 5GAHN 3CXCH 1K73J 3PIPJ 1Q86J 1YJ9H 1VQ7H 1VQOH 5DM7J 3OW2H 5HL7J 1VQPH 3J7ZM 2ZJRJ 3PIOJ 3CC4H 2QA4H 5JVHJ 2OTJH 1QVFH 1KC8J 3CCRH 1K9MJ 1VQ6H 1VQ4H 1VQKH 3DLLJ 4IOAJ 4WFBJ 5JVGJ 5MLCO 2ZJPJ 1N8RJ 1YJNH 2ZJQJ 1YIJH 3CPWH 3I55H 3CC7H 1YITH 1JJ2H 1Y69K 3G4SH 1Q82J 1VQLH 4WFNJ 4WCEJ 5DM6J 3CMAH 5GAGN 1S72H 4WFAJ 3CCMH 3CCQH 3CC2H 1VQNH 1M1KJ 3CCVH 3CD6H 1VQ8H 2PA2A 4U67J 3G6EH 3CF5J 1M90J 4IOCJ 5H1SO 5GADN 1KQSH 2OTLH 1YHQH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IO9 J;  1K8A J;  3G71 H;  3I56 H;  1VQ9 H;  4UY8 M;  3CCU H;  1QVG H;  3CCS H;  1YJW H;  2QEX H;  1W2B H;  1Q81 J;  3CCE H;  5AN9 F;  1WKI A;  1VQM H;  1Q7Y J;  1VQ5 H;  5GAE N;  3CME H;  4WF9 J;  1KD1 J;  1YI2 H;  3CCL H;  3CCJ H;  1NJI J;  5GAH N;  3CXC H;  1K73 J;  3PIP J;  1Q86 J;  1YJ9 H;  1VQ7 H;  1VQO H;  5DM7 J;  3OW2 H;  5HL7 J;  1VQP H;  3J7Z M;  2ZJR J;  3PIO J;  3CC4 H;  2QA4 H;  5JVH J;  2OTJ H;  1QVF H;  1KC8 J;  3CCR H;  1K9M J;  1VQ6 H;  1VQ4 H;  1VQK H;  3DLL J;  4IOA J;  4WFB J;  5JVG J;  5MLC O;  2ZJP J;  1N8R J;  1YJN H;  2ZJQ J;  1YIJ H;  3CPW H;  3I55 H;  3CC7 H;  1YIT H;  1JJ2 H;  1Y69 K;  3G4S H;  1Q82 J;  1VQL H;  4WFN J;  4WCE J;  5DM6 J;  3CMA H;  5GAG N;  1S72 H;  4WFA J;  3CCM H;  3CCQ H;  3CC2 H;  1VQN H;  1M1K J;  3CCV H;  3CD6 H;  1VQ8 H;  2PA2 A;  4U67 J;  3G6E H;  3CF5 J;  1M90 J;  4IOC J;  5H1S O;  5GAD N;  1KQS H;  2OTL H;  1YHQ H; 
#chains in the Genus database with same CATH topology
 4IO9 J;  1QPO A;  4GA6 A;  1K8A J;  1YTE A;  3G71 H;  2I1O A;  3C2V A;  3I56 H;  1VQ9 H;  4UY8 M;  1DGJ A;  3CCU H;  1QVG H;  3CCS H;  1YJW H;  1N5X A;  2QEX H;  1W2B H;  1Q81 J;  5HUO A;  2WP4 A;  3CCE H;  1ZXI B;  1OTP A;  1NVJ A;  2W54 B;  4GA4 A;  5AN9 F;  1BRW A;  1WKI A;  4X46 A;  3RPF A;  3SR6 C;  3ETR C;  2E3T A;  4EAF A;  3NVY C;  1VQM H;  3WNZ A;  1Q7Y J;  1VQ5 H;  3FAH A;  1UOU A;  4EAD A;  5GAE N;  1FFU B;  2W3R B;  1VDV A;  3CME H;  4WF9 J;  3NVZ C;  3CCL H;  1YI2 H;  1KD1 J;  3CCJ H;  2B7Q A;  1NJI J;  1SIJ A;  4USA A;  3FC4 A;  5EP8 A;  5AYZ A;  5GAH N;  2B7P A;  5AYY A;  3CXC H;  3L0G A;  1K73 J;  3PIP J;  2WK6 A;  1Q86 J;  4C7Z A;  3NVW C;  1YJ9 H;  5AYX A;  1VQO H;  1VQ7 H;  2OTL H;  5DM7 J;  3OW2 H;  5HL7 J;  1VQP H;  5MPO C;  1QPQ A;  3J7Z M;  2ZJR J;  2WK5 A;  3PIO J;  3CC4 H;  2QA4 H;  5JVH J;  1V97 A;  2OTJ H;  3B9J C;  3WO0 A;  1JRP B;  4AP8 A;  1QVF H;  1KC8 J;  3CCR H;  1FMA E;  1K9M J;  4GA5 A;  1VQ6 H;  1YTD A;  1N60 B;  1VQ4 H;  4US8 A;  1NVI E;  3AN1 A;  1VQK H;  2OMD A;  3DLL J;  1FM0 E;  3NS1 C;  1N63 B;  3NVV C;  4XR5 A;  4IOA J;  2W3S B;  4KWW A;  2B7N A;  4WFB J;  5JVG J;  3AMZ A;  2I14 A;  2W55 B;  5MLC O;  5EY3 A;  1N5W B;  5HUL A;  2ZJP J;  1N8R J;  3C2R A;  4US9 A;  3VMM A;  1QAP A;  1JRO B;  1YJN H;  3TQV A;  2ZJQ J;  4I9A A;  1YIJ H;  3C2O A;  2DSJ A;  2J0F A;  3GNN A;  3CPW H;  3I55 H;  3C2F A;  3CC7 H;  3BII E;  1RM6 A;  1YIT H;  1JJ2 H;  1FO4 A;  1Y69 K;  1AZY A;  2Q5W E;  3G4S H;  1Q82 J;  1VQL H;  3NRZ C;  2JBM A;  4WFN J;  1SB3 A;  4KWV A;  5DM6 J;  1N61 B;  1QPN A;  3WO1 A;  4WCE J;  1FIQ C;  3CMA H;  4ZOH A;  1VLB A;  5GAG N;  3EUB 4;  1S72 H;  4WFA J;  1FFV B;  3CCM H;  3H5Q A;  1O4U A;  5HUP A;  3CCQ H;  1N62 B;  1WYG A;  3C2E A;  3CC2 H;  1X1O A;  1VQN H;  1M1K J;  3CCV H;  3CD6 H;  4LHM A;  4YEK A;  3PAJ A;  2QIE A;  1VQ8 H;  2PA2 A;  4U67 J;  3AM9 A;  3G6E H;  3CF5 J;  1M90 J;  4C80 A;  4IOC J;  4YYY A;  5H1S O;  1YTK A;  1QPR A;  5GAD N;  1KQS H;  3L4P A;  2TPT A;  1YHQ H;  4C7Y A; 
#chains in the Genus database with same CATH homology
 4IO9 J;  1K8A J;  3G71 H;  3I56 H;  1VQ9 H;  4UY8 M;  3CCU H;  1QVG H;  3CCS H;  1YJW H;  2QEX H;  1W2B H;  1Q81 J;  3CCE H;  5AN9 F;  1WKI A;  1VQM H;  1Q7Y J;  1VQ5 H;  5GAE N;  3CME H;  4WF9 J;  1KD1 J;  1YI2 H;  3CCL H;  3CCJ H;  1NJI J;  5GAH N;  3CXC H;  1K73 J;  3PIP J;  1Q86 J;  1YJ9 H;  1VQ7 H;  1VQO H;  5DM7 J;  3OW2 H;  5HL7 J;  1VQP H;  3J7Z M;  2ZJR J;  3PIO J;  3CC4 H;  2QA4 H;  5JVH J;  2OTJ H;  1QVF H;  1KC8 J;  3CCR H;  1K9M J;  1VQ6 H;  1VQ4 H;  1VQK H;  3DLL J;  4IOA J;  4WFB J;  5JVG J;  5MLC O;  2ZJP J;  1N8R J;  1YJN H;  2ZJQ J;  1YIJ H;  3CPW H;  3I55 H;  3CC7 H;  1YIT H;  1JJ2 H;  1Y69 K;  3G4S H;  1Q82 J;  1VQL H;  4WFN J;  4WCE J;  5DM6 J;  3CMA H;  5GAG N;  1S72 H;  4WFA J;  3CCM H;  3CCQ H;  3CC2 H;  1VQN H;  1M1K J;  3CCV H;  3CD6 H;  1VQ8 H;  2PA2 A;  4U67 J;  3G6E H;  3CF5 J;  1M90 J;  4IOC J;  5H1S O;  5GAD N;  1KQS H;  2OTL H;  1YHQ H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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