1YJWH

Crystal structure of quinupristin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords 23S RIBOSOMAL RNA
total genus 38
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2005-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1yjwH00
3CMEH 4UY8M 4WFBJ 3CC4H 1VQ4H 3CXCH 1M1KJ 5JVGJ 3DLLJ 4IO9J 1VQ9H 1KC8J 3J7ZM 3CCSH 1YHQH 1Q81J 1Q7YJ 1K73J 4IOCJ 5GAHN 2ZJPJ 3CMAH 2ZJQJ 1YJNH 1VQKH 1VQNH 3I56H 1Q86J 1Q82J 4WFNJ 1YJ9H 2QEXH 4WF9J 1N8RJ 3CCQH 4WCEJ 1M90J 1YIJH 3CD6H 5HL7J 1VQ5H 2PA2A 3CCEH 2ZJRJ 3CPWH 1NJIJ 1W2BH 5DM6J 3CCVH 1YITH 4WFAJ 5JVHJ 5AN9F 1VQ8H 2OTJH 5MLCO 5GADN 3OW2H 3PIPJ 1QVFH 3G71H 1KD1J 5DM7J 3CCLH 3CF5J 1WKIA 4IOAJ 3CCMH 3CCUH 3CC2H 3PIOJ 1KQSH 4U67J 1K9MJ 1VQ7H 2OTLH 3G4SH 1YI2H 1QVGH 3I55H 1VQ6H 3CC7H 3CCRH 3CCJH 1JJ2H 1VQLH 1Y69K 1YJWH 2QA4H 3G6EH 1S72H 1VQMH 5H1SO 1K8AJ 1VQPH 5GAEN 1VQOH 5GAGN
chains in the Genus database with same CATH superfamily
3CMEH 4UY8M 4WFBJ 3CC4H 1VQ4H 3ETRC 3CXCH 1M1KJ 1YTEA 1RM6A 1X1OA 5JVGJ 3DLLJ 4IO9J 1NVJA 2JBMA 4C7YA 2DSJA 1QPNA 2Q5WE 1FO4A 1VQ9H 1KC8J 1SB3A 3J7ZM 5GAGN 3FC4A 3CCSH 4EAFA 1YHQH 1Q81J 5EY3A 1SIJA 2J0FA 4KWVA 4GA6A 1Q7YJ 1K73J 4IOCJ 3C2OA 3B9JC 3C2RA 2WK6A 5GAHN 2ZJPJ 3CMAH 2TPTA 3L0GA 2I1OA 3NVWC 4US8A 2ZJQJ 1YJNH 3AN1A 1VQKH 1OTPA 1YTKA 1VQNH 3I56H 1Q86J 1ZXIB 1JROB 3BIIE 4C80A 1Q82J 1N63B 1O4UA 2QIEA 4X46A 4WFNJ 1YJ9H 2WP4A 2I14A 1YTDA 3TQVA 5HULA 3NRZC 2QEXH 4WF9J 1N8RJ 5AYYA 3CCQH 4WCEJ 1M90J 1YIJH 3CD6H 5AYXA 1N61B 1VLBA 4AP8A 5HL7J 1VQ5H 2W54B 2PA2A 3VMMA 4KWWA 3NVZC 5EP8A 4USAA 3CCEH 2ZJRJ 1N60B 3CPWH 1QPRA 1NJIJ 1W2BH 1VDVA 4I9AA 2E3TA 4GA4A 1NVIE 5DM6J 4ZOHA 4WFAJ 3CCVH 5JVHJ 1YITH 1N62B 5AN9F 1BRWA 1VQ8H 2OTJH 5MLCO 2WK5A 4US9A 4XR5A 5GADN 5HUOA 3OW2H 3PIPJ 1FMAE 3AMZA 4EADA 1QVFH 3C2EA 3G71H 1JRPB 3WNZA 2W55B 2W3SB 1QPQA 1KD1J 5DM7J 3CCLH 3CF5J 3WO0A 1WKIA 4IOAJ 5AYZA 3CCMH 3L4PA 3CCUH 2W3RB 3NS1C 1N5WB 5MPOC 3CC2H 3PIOJ 1FFUB 1KQSH 4U67J 1K9MJ 1VQ7H 4YYYA 2B7QA 3GNNA 2OTLH 3G4SH 1WYGA 3H5QA 1QPOA 1AZYA 1YI2H 3NVYC 1FIQC 1QVGH 3C2VA 1N5XA 4LHMA 3I55H 1VQ6H 3CC7H 1DGJA 3CCRH 3NVVC 3FAHA 4GA5A 1JJ2H 1FFVB 3PAJA 1FM0E 3CCJH 2OMDA 3RPFA 1V97A 1VQLH 5HUPA 1UOUA 4YEKA 1Y69K 1YJWH 1QAPA 3G6EH 2QA4H 1S72H 1VQMH 2B7PA 2B7NA 5H1SO 3SR6C 1K8AJ 3WO1A 1VQPH 4C7ZA 5GAEN 3AM9A 1VQOH 3EUB4 3C2FA
chains in the Genus database with same CATH topology
3CMEH 4UY8M 4WFBJ 3CC4H 1VQ4H 3CXCH 1M1KJ 5JVGJ 3DLLJ 4IO9J 1VQ9H 1KC8J 3J7ZM 3CCSH 1YHQH 1Q81J 1Q7YJ 1K73J 4IOCJ 5GAHN 2ZJPJ 3CMAH 2ZJQJ 1YJNH 1VQKH 1VQNH 3I56H 1Q86J 1Q82J 4WFNJ 1YJ9H 2QEXH 4WF9J 1N8RJ 3CCQH 4WCEJ 1M90J 1YIJH 3CD6H 5HL7J 1VQ5H 2PA2A 3CCEH 2ZJRJ 3CPWH 1NJIJ 1W2BH 5DM6J 3CCVH 1YITH 4WFAJ 5JVHJ 5AN9F 1VQ8H 2OTJH 5MLCO 5GADN 3OW2H 3PIPJ 1QVFH 3G71H 1KD1J 5DM7J 3CCLH 3CF5J 1WKIA 4IOAJ 3CCMH 3CCUH 3CC2H 3PIOJ 1KQSH 4U67J 1K9MJ 1VQ7H 2OTLH 3G4SH 1YI2H 1QVGH 3I55H 1VQ6H 3CC7H 3CCRH 3CCJH 1JJ2H 1VQLH 1Y69K 1YJWH 2QA4H 3G6EH 1S72H 1VQMH 5H1SO 1K8AJ 1VQPH 5GAEN 1VQOH 5GAGN
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CME H;  4UY8 M;  4WFB J;  3CC4 H;  1VQ4 H;  3CXC H;  1M1K J;  5JVG J;  3DLL J;  4IO9 J;  1VQ9 H;  1KC8 J;  3J7Z M;  3CCS H;  1YHQ H;  1Q81 J;  1Q7Y J;  1K73 J;  4IOC J;  5GAH N;  2ZJP J;  3CMA H;  2ZJQ J;  1YJN H;  1VQK H;  1VQN H;  3I56 H;  1Q86 J;  1Q82 J;  4WFN J;  1YJ9 H;  2QEX H;  4WF9 J;  1N8R J;  3CCQ H;  4WCE J;  1M90 J;  1YIJ H;  3CD6 H;  5HL7 J;  1VQ5 H;  2PA2 A;  3CCE H;  2ZJR J;  3CPW H;  1NJI J;  1W2B H;  5DM6 J;  3CCV H;  1YIT H;  4WFA J;  5JVH J;  5AN9 F;  1VQ8 H;  2OTJ H;  5MLC O;  5GAD N;  3OW2 H;  3PIP J;  1QVF H;  3G71 H;  1KD1 J;  5DM7 J;  3CCL H;  3CF5 J;  1WKI A;  4IOA J;  3CCM H;  3CCU H;  3CC2 H;  3PIO J;  1KQS H;  4U67 J;  1K9M J;  1VQ7 H;  2OTL H;  3G4S H;  1YI2 H;  1QVG H;  3I55 H;  1VQ6 H;  3CC7 H;  3CCR H;  3CCJ H;  1JJ2 H;  1VQL H;  1Y69 K;  1YJW H;  2QA4 H;  3G6E H;  1S72 H;  1VQM H;  5H1S O;  1K8A J;  1VQP H;  5GAE N;  1VQO H;  5GAG N; 
#chains in the Genus database with same CATH topology
 3CME H;  4UY8 M;  4WFB J;  3CC4 H;  1VQ4 H;  3ETR C;  3CXC H;  1M1K J;  1YTE A;  1RM6 A;  1X1O A;  5JVG J;  3DLL J;  4IO9 J;  1NVJ A;  2JBM A;  4C7Y A;  2DSJ A;  1QPN A;  2Q5W E;  1FO4 A;  1VQ9 H;  1KC8 J;  1SB3 A;  3J7Z M;  5GAG N;  3FC4 A;  3CCS H;  4EAF A;  1YHQ H;  1Q81 J;  5EY3 A;  1SIJ A;  2J0F A;  4KWV A;  4GA6 A;  1Q7Y J;  1K73 J;  4IOC J;  3C2O A;  3B9J C;  3C2R A;  2WK6 A;  5GAH N;  2ZJP J;  3CMA H;  2TPT A;  3L0G A;  2I1O A;  3NVW C;  4US8 A;  2ZJQ J;  1YJN H;  3AN1 A;  1VQK H;  1OTP A;  1YTK A;  1VQN H;  3I56 H;  1Q86 J;  1ZXI B;  1JRO B;  3BII E;  4C80 A;  1Q82 J;  1N63 B;  1O4U A;  2QIE A;  4X46 A;  4WFN J;  1YJ9 H;  2WP4 A;  2I14 A;  1YTD A;  3TQV A;  5HUL A;  3NRZ C;  2QEX H;  4WF9 J;  1N8R J;  5AYY A;  3CCQ H;  4WCE J;  1M90 J;  1YIJ H;  3CD6 H;  5AYX A;  1N61 B;  1VLB A;  4AP8 A;  5HL7 J;  1VQ5 H;  2W54 B;  2PA2 A;  3VMM A;  4KWW A;  3NVZ C;  5EP8 A;  4USA A;  3CCE H;  2ZJR J;  1N60 B;  3CPW H;  1QPR A;  1NJI J;  1W2B H;  1VDV A;  4I9A A;  2E3T A;  4GA4 A;  1NVI E;  5DM6 J;  4ZOH A;  4WFA J;  3CCV H;  5JVH J;  1YIT H;  1N62 B;  5AN9 F;  1BRW A;  1VQ8 H;  2OTJ H;  5MLC O;  2WK5 A;  4US9 A;  4XR5 A;  5GAD N;  5HUO A;  3OW2 H;  3PIP J;  1FMA E;  3AMZ A;  4EAD A;  1QVF H;  3C2E A;  3G71 H;  1JRP B;  3WNZ A;  2W55 B;  2W3S B;  1QPQ A;  1KD1 J;  5DM7 J;  3CCL H;  3CF5 J;  3WO0 A;  1WKI A;  4IOA J;  5AYZ A;  3CCM H;  3L4P A;  3CCU H;  2W3R B;  3NS1 C;  1N5W B;  5MPO C;  3CC2 H;  3PIO J;  1FFU B;  1KQS H;  4U67 J;  1K9M J;  1VQ7 H;  4YYY A;  2B7Q A;  3GNN A;  2OTL H;  3G4S H;  1WYG A;  3H5Q A;  1QPO A;  1AZY A;  1YI2 H;  3NVY C;  1FIQ C;  1QVG H;  3C2V A;  1N5X A;  4LHM A;  3I55 H;  1VQ6 H;  3CC7 H;  1DGJ A;  3CCR H;  3NVV C;  3FAH A;  4GA5 A;  1JJ2 H;  1FFV B;  3PAJ A;  1FM0 E;  3CCJ H;  2OMD A;  3RPF A;  1V97 A;  1VQL H;  5HUP A;  1UOU A;  4YEK A;  1Y69 K;  1YJW H;  1QAP A;  3G6E H;  2QA4 H;  1S72 H;  1VQM H;  2B7P A;  2B7N A;  5H1S O;  3SR6 C;  1K8A J;  3WO1 A;  1VQP H;  4C7Z A;  5GAE N;  3AM9 A;  1VQO H;  3EUB 4;  3C2F A; 
#chains in the Genus database with same CATH homology
 3CME H;  4UY8 M;  4WFB J;  3CC4 H;  1VQ4 H;  3CXC H;  1M1K J;  5JVG J;  3DLL J;  4IO9 J;  1VQ9 H;  1KC8 J;  3J7Z M;  3CCS H;  1YHQ H;  1Q81 J;  1Q7Y J;  1K73 J;  4IOC J;  5GAH N;  2ZJP J;  3CMA H;  2ZJQ J;  1YJN H;  1VQK H;  1VQN H;  3I56 H;  1Q86 J;  1Q82 J;  4WFN J;  1YJ9 H;  2QEX H;  4WF9 J;  1N8R J;  3CCQ H;  4WCE J;  1M90 J;  1YIJ H;  3CD6 H;  5HL7 J;  1VQ5 H;  2PA2 A;  3CCE H;  2ZJR J;  3CPW H;  1NJI J;  1W2B H;  5DM6 J;  3CCV H;  1YIT H;  4WFA J;  5JVH J;  5AN9 F;  1VQ8 H;  2OTJ H;  5MLC O;  5GAD N;  3OW2 H;  3PIP J;  1QVF H;  3G71 H;  1KD1 J;  5DM7 J;  3CCL H;  3CF5 J;  1WKI A;  4IOA J;  3CCM H;  3CCU H;  3CC2 H;  3PIO J;  1KQS H;  4U67 J;  1K9M J;  1VQ7 H;  2OTL H;  3G4S H;  1YI2 H;  1QVG H;  3I55 H;  1VQ6 H;  3CC7 H;  3CCR H;  3CCJ H;  1JJ2 H;  1VQL H;  1Y69 K;  1YJW H;  2QA4 H;  3G6E H;  1S72 H;  1VQM H;  5H1S O;  1K8A J;  1VQP H;  5GAE N;  1VQO H;  5GAG N; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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