1M1KJ

Co-crystal structure of azithromycin bound to the 50s ribosomal subunit of haloarcula marismortui
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
167
structure length
156
Chain Sequence
KPGAMYRNSSKPAYTRREYISGIPGKKIAQFDMGNNGAGPTYPAQVELVVEKPVQIRHNALEAARVAANRYVQNSGAAANYKFRIRKFPFHVIRENKDGMRAPFGKPVGTAARVHGANHIFIAWVNPDPNVEEAWRRAKMKVTPTINIDSSPAGNA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structures of four macrolide antibiotics bound to the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RRNA
total genus 27
structure length 156
sequence length 167
ec nomenclature
pdb deposition date 2002-06-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1m1kJ00
2QA4H 1YITH 2ZJPJ 1KC8J 4WCEJ 1KQSH 4UY8M 1K9MJ 2OTJH 3G4SH 1VQOH 1VQ8H 1S72H 1YIJH 4WFNJ 1VQNH 5DM6J 3I55H 1WKIA 1Q7YJ 5AN9F 1W2BH 2PA2A 1Q82J 4WF9J 5GADN 3CCJH 3CCSH 2QEXH 3CCQH 1N8RJ 1M90J 1NJIJ 2OTLH 1JJ2H 3PIOJ 5MLCO 1Q86J 1VQ6H 1VQ5H 1YJNH 1VQ4H 5HL7J 5JVGJ 3G6EH 1Q81J 3CC7H 4WFBJ 1QVFH 3J7ZM 3CPWH 1VQMH 3CF5J 3CCVH 3OW2H 3PIPJ 1K8AJ 1VQ9H 4U67J 3G71H 5GAHN 3CC4H 3CXCH 4IO9J 3CMAH 2ZJRJ 3I56H 1VQKH 1VQLH 3CCMH 3CD6H 3CMEH 1YI2H 1YHQH 4IOAJ 3CCUH 1K73J 3CCLH 5H1SO 5DM7J 4WFAJ 3CCEH 3DLLJ 1YJWH 1Y69K 1QVGH 1VQPH 2ZJQJ 3CC2H 1KD1J 3CCRH 1YJ9H 1M1KJ 5GAGN 1VQ7H 5GAEN 4IOCJ 5JVHJ
chains in the Genus database with same CATH superfamily
2QA4H 1YTEA 5MPOC 1YITH 2ZJPJ 1N5XA 3AMZA 3RPFA 2TPTA 1KC8J 4WCEJ 1KQSH 4UY8M 1DGJA 1N63B 3FC4A 3FAHA 3NVWC 3G4SH 1K9MJ 3C2FA 2OTJH 2OMDA 1FIQC 1NVJA 3VMMA 4EADA 1VQOH 1VQ8H 1ZXIB 1AZYA 2E3TA 5AYZA 1N60B 5AYYA 4X46A 1YIJH 1S72H 2DSJA 3ETRC 4WFNJ 2WK6A 1VQNH 5DM6J 3I55H 1WKIA 1FFVB 4LHMA 5AN9F 1Q7YJ 1WYGA 1W2BH 3BIIE 4US9A 5AYXA 1VDVA 2PA2A 2JBMA 1Q82J 5EY3A 4WF9J 1V97A 1QAPA 2W54B 3AN1A 1NVIE 1QPQA 3NS1C 3L0GA 4GA5A 5GADN 3CCJH 3CCSH 1SB3A 2QEXH 3CCQH 1N8RJ 3AM9A 1M90J 1NJIJ 2OTLH 4EAFA 1JJ2H 3PIOJ 5MLCO 1BRWA 1OTPA 3B9JC 1Q86J 2B7PA 3SR6C 1VQ6H 4GA6A 4YYYA 1O4UA 1VQ5H 4KWVA 1YJNH 1X1OA 1VQ4H 4USAA 5HL7J 5JVGJ 3G6EH 2W3RB 1Q81J 2WP4A 3CC7H 1JRPB 4WFBJ 1QVFH 4XR5A 3C2OA 4ZOHA 1FO4A 2W3SB 1FFUB 1JROB 3J7ZM 3CPWH 1VQMH 3NRZC 1YTDA 3EUB4 3NVYC 3CF5J 3CCVH 4C80A 3OW2H 3C2VA 3PIPJ 3TQVA 2QIEA 3WO1A 1K8AJ 1VQ9H 3C2EA 4U67J 3G71H 5GAHN 3CC4H 1SIJA 3CXCH 4IO9J 2W55B 3CMAH 2ZJRJ 3NVZC 2B7NA 1QPRA 4GA4A 4I9AA 3I56H 5HUPA 1VQKH 1N5WB 1VQLH 1N62B 3CCMH 3H5QA 3CD6H 3WO0A 3CMEH 1YI2H 2B7QA 2I1OA 2WK5A 3PAJA 1FM0E 5EP8A 1YHQH 4IOAJ 3CCUH 1K73J 3CCLH 5H1SO 5DM7J 4WFAJ 3CCEH 3NVVC 1UOUA 3DLLJ 1YJWH 1Y69K 3C2RA 4C7ZA 3L4PA 1VLBA 1QVGH 5HUOA 1N61B 1YTKA 1VQPH 2ZJQJ 3WNZA 3CC2H 1KD1J 1RM6A 4IOCJ 4C7YA 1FMAE 2I14A 3CCRH 1YJ9H 2Q5WE 1M1KJ 3GNNA 5GAGN 4US8A 1QPNA 1VQ7H 4KWWA 1QPOA 4AP8A 5GAEN 4YEKA 5HULA 2J0FA 5JVHJ
chains in the Genus database with same CATH topology
2QA4H 1YITH 2ZJPJ 1KC8J 4WCEJ 1KQSH 4UY8M 1K9MJ 2OTJH 3G4SH 1VQOH 1VQ8H 1S72H 1YIJH 4WFNJ 1VQNH 5DM6J 3I55H 1WKIA 1Q7YJ 5AN9F 1W2BH 2PA2A 1Q82J 4WF9J 5GADN 3CCJH 3CCSH 2QEXH 3CCQH 1N8RJ 1M90J 1NJIJ 2OTLH 1JJ2H 3PIOJ 5MLCO 1Q86J 1VQ6H 1VQ5H 1YJNH 1VQ4H 5HL7J 5JVGJ 3G6EH 1Q81J 3CC7H 4WFBJ 1QVFH 3J7ZM 3CPWH 1VQMH 3CF5J 3CCVH 3OW2H 3PIPJ 1K8AJ 1VQ9H 4U67J 3G71H 5GAHN 3CC4H 3CXCH 4IO9J 3CMAH 2ZJRJ 3I56H 1VQKH 1VQLH 3CCMH 3CD6H 3CMEH 1YI2H 1YHQH 4IOAJ 3CCUH 1K73J 3CCLH 5H1SO 5DM7J 4WFAJ 3CCEH 3DLLJ 1YJWH 1Y69K 1QVGH 1VQPH 2ZJQJ 3CC2H 1KD1J 3CCRH 1YJ9H 1M1KJ 5GAGN 1VQ7H 5GAEN 4IOCJ 5JVHJ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QA4 H;  1YIT H;  2ZJP J;  1KC8 J;  4WCE J;  1KQS H;  4UY8 M;  1K9M J;  2OTJ H;  3G4S H;  1VQO H;  1VQ8 H;  1S72 H;  1YIJ H;  4WFN J;  1VQN H;  5DM6 J;  3I55 H;  1WKI A;  1Q7Y J;  5AN9 F;  1W2B H;  2PA2 A;  1Q82 J;  4WF9 J;  5GAD N;  3CCJ H;  3CCS H;  2QEX H;  3CCQ H;  1N8R J;  1M90 J;  1NJI J;  2OTL H;  1JJ2 H;  3PIO J;  5MLC O;  1Q86 J;  1VQ6 H;  1VQ5 H;  1YJN H;  1VQ4 H;  5HL7 J;  5JVG J;  3G6E H;  1Q81 J;  3CC7 H;  4WFB J;  1QVF H;  3J7Z M;  3CPW H;  1VQM H;  3CF5 J;  3CCV H;  3OW2 H;  3PIP J;  1K8A J;  1VQ9 H;  4U67 J;  3G71 H;  5GAH N;  3CC4 H;  3CXC H;  4IO9 J;  3CMA H;  2ZJR J;  3I56 H;  1VQK H;  1VQL H;  3CCM H;  3CD6 H;  3CME H;  1YI2 H;  1YHQ H;  4IOA J;  3CCU H;  1K73 J;  3CCL H;  5H1S O;  5DM7 J;  4WFA J;  3CCE H;  3DLL J;  1YJW H;  1Y69 K;  1QVG H;  1VQP H;  2ZJQ J;  3CC2 H;  1KD1 J;  3CCR H;  1YJ9 H;  1M1K J;  5GAG N;  1VQ7 H;  5GAE N;  4IOC J;  5JVH J; 
#chains in the Genus database with same CATH topology
 2QA4 H;  1YTE A;  5MPO C;  1YIT H;  2ZJP J;  1N5X A;  3AMZ A;  3RPF A;  2TPT A;  1KC8 J;  4WCE J;  1KQS H;  4UY8 M;  1DGJ A;  1N63 B;  3FC4 A;  3FAH A;  3NVW C;  3G4S H;  1K9M J;  3C2F A;  2OTJ H;  2OMD A;  1FIQ C;  1NVJ A;  3VMM A;  4EAD A;  1VQO H;  1VQ8 H;  1ZXI B;  1AZY A;  2E3T A;  5AYZ A;  1N60 B;  5AYY A;  4X46 A;  1YIJ H;  1S72 H;  2DSJ A;  3ETR C;  4WFN J;  2WK6 A;  1VQN H;  5DM6 J;  3I55 H;  1WKI A;  1FFV B;  4LHM A;  5AN9 F;  1Q7Y J;  1WYG A;  1W2B H;  3BII E;  4US9 A;  5AYX A;  1VDV A;  2PA2 A;  2JBM A;  1Q82 J;  5EY3 A;  4WF9 J;  1V97 A;  1QAP A;  2W54 B;  3AN1 A;  1NVI E;  1QPQ A;  3NS1 C;  3L0G A;  4GA5 A;  5GAD N;  3CCJ H;  3CCS H;  1SB3 A;  2QEX H;  3CCQ H;  1N8R J;  3AM9 A;  1M90 J;  1NJI J;  2OTL H;  4EAF A;  1JJ2 H;  3PIO J;  5MLC O;  1BRW A;  1OTP A;  3B9J C;  1Q86 J;  2B7P A;  3SR6 C;  1VQ6 H;  4GA6 A;  4YYY A;  1O4U A;  1VQ5 H;  4KWV A;  1YJN H;  1X1O A;  1VQ4 H;  4USA A;  5HL7 J;  5JVG J;  3G6E H;  2W3R B;  1Q81 J;  2WP4 A;  3CC7 H;  1JRP B;  4WFB J;  1QVF H;  4XR5 A;  3C2O A;  4ZOH A;  1FO4 A;  2W3S B;  1FFU B;  1JRO B;  3J7Z M;  3CPW H;  1VQM H;  3NRZ C;  1YTD A;  3EUB 4;  3NVY C;  3CF5 J;  3CCV H;  4C80 A;  3OW2 H;  3C2V A;  3PIP J;  3TQV A;  2QIE A;  3WO1 A;  1K8A J;  1VQ9 H;  3C2E A;  4U67 J;  3G71 H;  5GAH N;  3CC4 H;  1SIJ A;  3CXC H;  4IO9 J;  2W55 B;  3CMA H;  2ZJR J;  3NVZ C;  2B7N A;  1QPR A;  4GA4 A;  4I9A A;  3I56 H;  5HUP A;  1VQK H;  1N5W B;  1VQL H;  1N62 B;  3CCM H;  3H5Q A;  3CD6 H;  3WO0 A;  3CME H;  1YI2 H;  2B7Q A;  2I1O A;  2WK5 A;  3PAJ A;  1FM0 E;  5EP8 A;  1YHQ H;  4IOA J;  3CCU H;  1K73 J;  3CCL H;  5H1S O;  5DM7 J;  4WFA J;  3CCE H;  3NVV C;  1UOU A;  3DLL J;  1YJW H;  1Y69 K;  3C2R A;  4C7Z A;  3L4P A;  1VLB A;  1QVG H;  5HUO A;  1N61 B;  1YTK A;  1VQP H;  2ZJQ J;  3WNZ A;  3CC2 H;  1KD1 J;  1RM6 A;  4IOC J;  4C7Y A;  1FMA E;  2I14 A;  3CCR H;  1YJ9 H;  2Q5W E;  1M1K J;  3GNN A;  5GAG N;  4US8 A;  1QPN A;  1VQ7 H;  4KWW A;  1QPO A;  4AP8 A;  5GAE N;  4YEK A;  5HUL A;  2J0F A;  5JVH J; 
#chains in the Genus database with same CATH homology
 2QA4 H;  1YIT H;  2ZJP J;  1KC8 J;  4WCE J;  1KQS H;  4UY8 M;  1K9M J;  2OTJ H;  3G4S H;  1VQO H;  1VQ8 H;  1S72 H;  1YIJ H;  4WFN J;  1VQN H;  5DM6 J;  3I55 H;  1WKI A;  1Q7Y J;  5AN9 F;  1W2B H;  2PA2 A;  1Q82 J;  4WF9 J;  5GAD N;  3CCJ H;  3CCS H;  2QEX H;  3CCQ H;  1N8R J;  1M90 J;  1NJI J;  2OTL H;  1JJ2 H;  3PIO J;  5MLC O;  1Q86 J;  1VQ6 H;  1VQ5 H;  1YJN H;  1VQ4 H;  5HL7 J;  5JVG J;  3G6E H;  1Q81 J;  3CC7 H;  4WFB J;  1QVF H;  3J7Z M;  3CPW H;  1VQM H;  3CF5 J;  3CCV H;  3OW2 H;  3PIP J;  1K8A J;  1VQ9 H;  4U67 J;  3G71 H;  5GAH N;  3CC4 H;  3CXC H;  4IO9 J;  3CMA H;  2ZJR J;  3I56 H;  1VQK H;  1VQL H;  3CCM H;  3CD6 H;  3CME H;  1YI2 H;  1YHQ H;  4IOA J;  3CCU H;  1K73 J;  3CCL H;  5H1S O;  5DM7 J;  4WFA J;  3CCE H;  3DLL J;  1YJW H;  1Y69 K;  1QVG H;  1VQP H;  2ZJQ J;  3CC2 H;  1KD1 J;  3CCR H;  1YJ9 H;  1M1K J;  5GAG N;  1VQ7 H;  5GAE N;  4IOC J;  5JVH J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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