1YHQH

Crystal structure of azithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 42
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2005-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1yhqH00
1VQNH 1KQSH 3CCEH 3G4SH 1W2BH 2ZJPJ 4UY8M 1NJIJ 3CC2H 1Q86J 3CPWH 1QVGH 4IOCJ 5JVGJ 3J7ZM 1VQ4H 4WF9J 3CCSH 4WFBJ 1K73J 1YITH 1S72H 4U67J 1VQOH 5JVHJ 5GAHN 1KC8J 1YIJH 3CF5J 5HL7J 3I55H 3G6EH 1M1KJ 2QA4H 1VQPH 1WKIA 4WFAJ 4WCEJ 1Y69K 5DM7J 1VQ9H 1VQ8H 1YJNH 1VQMH 5DM6J 1M90J 1KD1J 1QVFH 1YJ9H 3CCMH 3CMEH 2QEXH 2ZJQJ 3CCJH 2ZJRJ 2PA2A 3CC4H 1N8RJ 3PIOJ 3G71H 3CCQH 5MLCO 1YI2H 3DLLJ 1YHQH 4WFNJ 1Q81J 1Q7YJ 1K8AJ 1YJWH 1JJ2H 3CXCH 5GAEN 1VQ6H 3CD6H 1VQKH 3CC7H 3CCUH 5GADN 3I56H 1VQ5H 3CMAH 3CCLH 2OTJH 5H1SO 3PIPJ 1VQLH 4IOAJ 2OTLH 3CCRH 1K9MJ 3OW2H 4IO9J 5AN9F 1Q82J 1VQ7H 3CCVH 5GAGN
chains in the Genus database with same CATH superfamily
1VQNH 2B7PA 4I9AA 3C2FA 2B7QA 1KQSH 2W54B 3CCEH 3G4SH 2QIEA 1W2BH 1N62B 2ZJPJ 2WK5A 4UY8M 1VDVA 1NJIJ 5EY3A 3CC2H 3SR6C 5HUPA 3L0GA 1Q86J 3CPWH 1QVGH 3PAJA 4IOCJ 5JVGJ 1X1OA 4C7ZA 3RPFA 1O4UA 3VMMA 4C7YA 3J7ZM 1VQ4H 4WF9J 3CCSH 4LHMA 3FC4A 1UOUA 4WFBJ 1K73J 5AYYA 1YITH 1S72H 4U67J 4KWVA 1NVJA 1V97A 2J0FA 3AMZA 4GA4A 4US8A 1VQOH 2I14A 5JVHJ 5GAHN 3GNNA 1QPQA 1KC8J 1YIJH 3WNZA 3CF5J 5HL7J 1AZYA 1N61B 1YTKA 3I55H 1N5WB 1YJWH 1RM6A 3G6EH 1FFUB 1OTPA 1QPNA 5HULA 1ZXIB 1M1KJ 1NVIE 2W55B 4YEKA 3NS1C 2QA4H 1QPRA 1SB3A 1QAPA 5AYXA 3FAHA 3H5QA 5AYZA 1VQPH 1SIJA 2JBMA 1N60B 1WKIA 4WFAJ 4WCEJ 3C2OA 1Y69K 5DM7J 4KWWA 3NVWC 2OMDA 1VQ9H 1VQ8H 3AM9A 1YJNH 4YYYA 1VQMH 3WO1A 5DM6J 5HUOA 1JRPB 1M90J 1KD1J 3EUB4 1QVFH 1YJ9H 3CCMH 4USAA 3C2EA 2I1OA 2W3RB 1FFVB 3CMEH 1N63B 4GA6A 2QEXH 2ZJQJ 3CCJH 1QPOA 2W3SB 2PA2A 3TQVA 3NRZC 4AP8A 1YTEA 3NVZC 3CC4H 2ZJRJ 1N8RJ 3NVVC 5MPOC 2WK6A 4EAFA 4US9A 3PIOJ 3G71H 3CCQH 5MLCO 1YI2H 3DLLJ 1YHQH 4WFNJ 1Q81J 1DGJA 1Q7YJ 4X46A 1JROB 4ZOHA 2TPTA 1N5XA 1VLBA 5GAEN 1FO4A 2E3TA 1WYGA 3CXCH 1JJ2H 1VQKH 1VQ6H 3CC7H 1K8AJ 3CD6H 3CCUH 5GADN 3C2RA 1FMAE 3I56H 3ETRC 3CMAH 1VQ5H 3CCLH 2OTJH 3NVYC 2DSJA 3BIIE 3B9JC 5H1SO 3PIPJ 5EP8A 1FIQC 1VQLH 4IOAJ 1BRWA 3C2VA 2OTLH 3CCRH 4C80A 3WO0A 2B7NA 1K9MJ 4IO9J 3OW2H 5AN9F 4GA5A 1Q82J 1VQ7H 3CCVH 4EADA 5GAGN 3L4PA 3AN1A 1FM0E 2Q5WE 4XR5A 2WP4A 1YTDA
chains in the Genus database with same CATH topology
1VQNH 1KQSH 3CCEH 3G4SH 1W2BH 2ZJPJ 4UY8M 1NJIJ 3CC2H 1Q86J 3CPWH 1QVGH 4IOCJ 5JVGJ 3J7ZM 1VQ4H 4WF9J 3CCSH 4WFBJ 1K73J 1YITH 1S72H 4U67J 1VQOH 5JVHJ 5GAHN 1KC8J 1YIJH 3CF5J 5HL7J 3I55H 3G6EH 1M1KJ 2QA4H 1VQPH 1WKIA 4WFAJ 4WCEJ 1Y69K 5DM7J 1VQ9H 1VQ8H 1YJNH 1VQMH 5DM6J 1M90J 1KD1J 1QVFH 1YJ9H 3CCMH 3CMEH 2QEXH 2ZJQJ 3CCJH 2ZJRJ 2PA2A 3CC4H 1N8RJ 3PIOJ 3G71H 3CCQH 5MLCO 1YI2H 3DLLJ 1YHQH 4WFNJ 1Q81J 1Q7YJ 1K8AJ 1YJWH 1JJ2H 3CXCH 5GAEN 1VQ6H 3CD6H 1VQKH 3CC7H 3CCUH 5GADN 3I56H 1VQ5H 3CMAH 3CCLH 2OTJH 5H1SO 3PIPJ 1VQLH 4IOAJ 2OTLH 3CCRH 1K9MJ 3OW2H 4IO9J 5AN9F 1Q82J 1VQ7H 3CCVH 5GAGN
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQN H;  1KQS H;  3CCE H;  3G4S H;  1W2B H;  2ZJP J;  4UY8 M;  1NJI J;  3CC2 H;  1Q86 J;  3CPW H;  1QVG H;  4IOC J;  5JVG J;  3J7Z M;  1VQ4 H;  4WF9 J;  3CCS H;  4WFB J;  1K73 J;  1YIT H;  1S72 H;  4U67 J;  1VQO H;  5JVH J;  5GAH N;  1KC8 J;  1YIJ H;  3CF5 J;  5HL7 J;  3I55 H;  3G6E H;  1M1K J;  2QA4 H;  1VQP H;  1WKI A;  4WFA J;  4WCE J;  1Y69 K;  5DM7 J;  1VQ9 H;  1VQ8 H;  1YJN H;  1VQM H;  5DM6 J;  1M90 J;  1KD1 J;  1QVF H;  1YJ9 H;  3CCM H;  3CME H;  2QEX H;  2ZJQ J;  3CCJ H;  2ZJR J;  2PA2 A;  3CC4 H;  1N8R J;  3PIO J;  3G71 H;  3CCQ H;  5MLC O;  1YI2 H;  3DLL J;  1YHQ H;  4WFN J;  1Q81 J;  1Q7Y J;  1K8A J;  1YJW H;  1JJ2 H;  3CXC H;  5GAE N;  1VQ6 H;  3CD6 H;  1VQK H;  3CC7 H;  3CCU H;  5GAD N;  3I56 H;  1VQ5 H;  3CMA H;  3CCL H;  2OTJ H;  5H1S O;  3PIP J;  1VQL H;  4IOA J;  2OTL H;  3CCR H;  1K9M J;  3OW2 H;  4IO9 J;  5AN9 F;  1Q82 J;  1VQ7 H;  3CCV H;  5GAG N; 
#chains in the Genus database with same CATH topology
 1VQN H;  2B7P A;  4I9A A;  3C2F A;  2B7Q A;  1KQS H;  2W54 B;  3CCE H;  3G4S H;  2QIE A;  1W2B H;  1N62 B;  2ZJP J;  2WK5 A;  4UY8 M;  1VDV A;  1NJI J;  5EY3 A;  3CC2 H;  3SR6 C;  5HUP A;  3L0G A;  1Q86 J;  3CPW H;  1QVG H;  3PAJ A;  4IOC J;  5JVG J;  1X1O A;  4C7Z A;  3RPF A;  1O4U A;  3VMM A;  4C7Y A;  3J7Z M;  1VQ4 H;  4WF9 J;  3CCS H;  4LHM A;  3FC4 A;  1UOU A;  4WFB J;  1K73 J;  5AYY A;  1YIT H;  1S72 H;  4U67 J;  4KWV A;  1NVJ A;  1V97 A;  2J0F A;  3AMZ A;  4GA4 A;  4US8 A;  1VQO H;  2I14 A;  5JVH J;  5GAH N;  3GNN A;  1QPQ A;  1KC8 J;  1YIJ H;  3WNZ A;  3CF5 J;  5HL7 J;  1AZY A;  1N61 B;  1YTK A;  3I55 H;  1N5W B;  1YJW H;  1RM6 A;  3G6E H;  1FFU B;  1OTP A;  1QPN A;  5HUL A;  1ZXI B;  1M1K J;  1NVI E;  2W55 B;  4YEK A;  3NS1 C;  2QA4 H;  1QPR A;  1SB3 A;  1QAP A;  5AYX A;  3FAH A;  3H5Q A;  5AYZ A;  1VQP H;  1SIJ A;  2JBM A;  1N60 B;  1WKI A;  4WFA J;  4WCE J;  3C2O A;  1Y69 K;  5DM7 J;  4KWW A;  3NVW C;  2OMD A;  1VQ9 H;  1VQ8 H;  3AM9 A;  1YJN H;  4YYY A;  1VQM H;  3WO1 A;  5DM6 J;  5HUO A;  1JRP B;  1M90 J;  1KD1 J;  3EUB 4;  1QVF H;  1YJ9 H;  3CCM H;  4USA A;  3C2E A;  2I1O A;  2W3R B;  1FFV B;  3CME H;  1N63 B;  4GA6 A;  2QEX H;  2ZJQ J;  3CCJ H;  1QPO A;  2W3S B;  2PA2 A;  3TQV A;  3NRZ C;  4AP8 A;  1YTE A;  3NVZ C;  3CC4 H;  2ZJR J;  1N8R J;  3NVV C;  5MPO C;  2WK6 A;  4EAF A;  4US9 A;  3PIO J;  3G71 H;  3CCQ H;  5MLC O;  1YI2 H;  3DLL J;  1YHQ H;  4WFN J;  1Q81 J;  1DGJ A;  1Q7Y J;  4X46 A;  1JRO B;  4ZOH A;  2TPT A;  1N5X A;  1VLB A;  5GAE N;  1FO4 A;  2E3T A;  1WYG A;  3CXC H;  1JJ2 H;  1VQK H;  1VQ6 H;  3CC7 H;  1K8A J;  3CD6 H;  3CCU H;  5GAD N;  3C2R A;  1FMA E;  3I56 H;  3ETR C;  3CMA H;  1VQ5 H;  3CCL H;  2OTJ H;  3NVY C;  2DSJ A;  3BII E;  3B9J C;  5H1S O;  3PIP J;  5EP8 A;  1FIQ C;  1VQL H;  4IOA J;  1BRW A;  3C2V A;  2OTL H;  3CCR H;  4C80 A;  3WO0 A;  2B7N A;  1K9M J;  4IO9 J;  3OW2 H;  5AN9 F;  4GA5 A;  1Q82 J;  1VQ7 H;  3CCV H;  4EAD A;  5GAG N;  3L4P A;  3AN1 A;  1FM0 E;  2Q5W E;  4XR5 A;  2WP4 A;  1YTD A; 
#chains in the Genus database with same CATH homology
 1VQN H;  1KQS H;  3CCE H;  3G4S H;  1W2B H;  2ZJP J;  4UY8 M;  1NJI J;  3CC2 H;  1Q86 J;  3CPW H;  1QVG H;  4IOC J;  5JVG J;  3J7Z M;  1VQ4 H;  4WF9 J;  3CCS H;  4WFB J;  1K73 J;  1YIT H;  1S72 H;  4U67 J;  1VQO H;  5JVH J;  5GAH N;  1KC8 J;  1YIJ H;  3CF5 J;  5HL7 J;  3I55 H;  3G6E H;  1M1K J;  2QA4 H;  1VQP H;  1WKI A;  4WFA J;  4WCE J;  1Y69 K;  5DM7 J;  1VQ9 H;  1VQ8 H;  1YJN H;  1VQM H;  5DM6 J;  1M90 J;  1KD1 J;  1QVF H;  1YJ9 H;  3CCM H;  3CME H;  2QEX H;  2ZJQ J;  3CCJ H;  2ZJR J;  2PA2 A;  3CC4 H;  1N8R J;  3PIO J;  3G71 H;  3CCQ H;  5MLC O;  1YI2 H;  3DLL J;  1YHQ H;  4WFN J;  1Q81 J;  1Q7Y J;  1K8A J;  1YJW H;  1JJ2 H;  3CXC H;  5GAE N;  1VQ6 H;  3CD6 H;  1VQK H;  3CC7 H;  3CCU H;  5GAD N;  3I56 H;  1VQ5 H;  3CMA H;  3CCL H;  2OTJ H;  5H1S O;  3PIP J;  1VQL H;  4IOA J;  2OTL H;  3CCR H;  1K9M J;  3OW2 H;  4IO9 J;  5AN9 F;  1Q82 J;  1VQ7 H;  3CCV H;  5GAG N; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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