1YI2H

Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 39
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2005-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1yi2H00
5JVGJ 2ZJQJ 4WFBJ 5DM6J 4WFAJ 5DM7J 2QA4H 1Q86J 5GAHN 5JVHJ 1Q82J 2QEXH 3CD6H 1VQ4H 3CCVH 3CF5J 3CMAH 1VQ6H 1VQMH 3CCEH 3CCMH 1YJNH 1VQKH 5AN9F 5HL7J 4WF9J 5GAGN 1K9MJ 1YI2H 3DLLJ 4IOAJ 3CC4H 3CCSH 1VQ8H 1VQOH 1WKIA 2OTJH 1VQLH 1VQPH 2PA2A 3CMEH 1M90J 4UY8M 4WFNJ 1VQ5H 3CCRH 4U67J 1Q7YJ 5GAEN 3G71H 3I56H 5H1SO 1YIJH 1QVFH 3I55H 1N8RJ 1QVGH 2OTLH 4IO9J 5MLCO 3G4SH 1YJ9H 3G6EH 4IOCJ 3CXCH 3CC7H 1KQSH 3CCUH 3CCJH 1JJ2H 1NJIJ 3CCLH 1Y69K 1VQ9H 1YHQH 2ZJPJ 5GADN 1VQNH 1Q81J 1KD1J 1VQ7H 1YITH 3OW2H 1YJWH 1S72H 3J7ZM 3CPWH 4WCEJ 1W2BH 1M1KJ 2ZJRJ 1K73J 3CC2H 1KC8J 3PIOJ 3CCQH 3PIPJ 1K8AJ
chains in the Genus database with same CATH superfamily
5AYYA 5JVGJ 2ZJQJ 3C2RA 4WFBJ 5DM6J 1FIQC 1SB3A 3L4PA 5DM7J 4WFAJ 3C2FA 2QA4H 1Q86J 5GAHN 5JVHJ 1Q82J 2QEXH 1JRPB 3CD6H 1VQ4H 3CCVH 1O4UA 3CF5J 5EY3A 1VDVA 3H5QA 1N63B 1NVIE 3B9JC 3CMAH 1VQ6H 1YTDA 1VQMH 1FFVB 5HUOA 2Q5WE 3WO0A 1SIJA 1WYGA 3CCEH 3CCMH 1YJNH 1VQKH 5AN9F 5HL7J 4AP8A 4WF9J 3AM9A 3EUB4 2I14A 2W3SB 1YTKA 4KWWA 4C7ZA 5GAGN 1K9MJ 1BRWA 4YYYA 1YI2H 3C2EA 1FMAE 1N61B 4US9A 3DLLJ 4IOAJ 1N62B 3CC4H 3CCSH 1VQ8H 1DGJA 1VQOH 2WK6A 4US8A 3C2OA 1WKIA 3NVYC 5AYXA 1OTPA 3WNZA 2OTJH 4EAFA 3AMZA 1VQLH 4USAA 2W55B 1RM6A 1QAPA 3NRZC 3VMMA 1VQPH 1N5WB 2B7PA 5HULA 4YEKA 2PA2A 3CMEH 1X1OA 2QIEA 1QPQA 1M90J 4UY8M 4WFNJ 3C2VA 4KWVA 1VQ5H 1N60B 1JROB 2E3TA 3CCRH 4U67J 1VLBA 3NVVC 1Q7YJ 5GAEN 5HUPA 1FFUB 3G71H 3I56H 5H1SO 1YIJH 2WK5A 1QVFH 4LHMA 2B7NA 1QPOA 3FAHA 3I55H 1N8RJ 1NVJA 1QVGH 2W54B 2OTLH 4IO9J 1ZXIB 5MLCO 3G4SH 1YJ9H 3G6EH 4IOCJ 3CXCH 3CC7H 1KQSH 3CCUH 5EP8A 3CCJH 1N5XA 1JJ2H 3NVWC 1NJIJ 3CCLH 1Y69K 4C80A 1FO4A 3WO1A 3L0GA 1YTEA 1VQ9H 3NS1C 3RPFA 1QPNA 4GA5A 2DSJA 1YHQH 5AYZA 3BIIE 2ZJPJ 4X46A 5GADN 1Q81J 4GA4A 1VQNH 1KD1J 1VQ7H 1V97A 1YITH 1FM0E 2J0FA 3GNNA 1AZYA 1QPRA 3OW2H 1YJWH 1S72H 3J7ZM 4I9AA 2OMDA 3CPWH 4ZOHA 2W3RB 2WP4A 2JBMA 2I1OA 1UOUA 4XR5A 3SR6C 4WCEJ 3AN1A 1W2BH 1M1KJ 2ZJRJ 5MPOC 1K73J 3TQVA 3CC2H 3ETRC 2TPTA 4GA6A 1KC8J 3FC4A 3NVZC 3PIOJ 3PAJA 4EADA 3CCQH 2B7QA 4C7YA 3PIPJ 1K8AJ
chains in the Genus database with same CATH topology
5JVGJ 2ZJQJ 4WFBJ 5DM6J 4WFAJ 5DM7J 2QA4H 1Q86J 5GAHN 5JVHJ 1Q82J 2QEXH 3CD6H 1VQ4H 3CCVH 3CF5J 3CMAH 1VQ6H 1VQMH 3CCEH 3CCMH 1YJNH 1VQKH 5AN9F 5HL7J 4WF9J 5GAGN 1K9MJ 1YI2H 3DLLJ 4IOAJ 3CC4H 3CCSH 1VQ8H 1VQOH 1WKIA 2OTJH 1VQLH 1VQPH 2PA2A 3CMEH 1M90J 4UY8M 4WFNJ 1VQ5H 3CCRH 4U67J 1Q7YJ 5GAEN 3G71H 3I56H 5H1SO 1YIJH 1QVFH 3I55H 1N8RJ 1QVGH 2OTLH 4IO9J 5MLCO 3G4SH 1YJ9H 3G6EH 4IOCJ 3CXCH 3CC7H 1KQSH 3CCUH 3CCJH 1JJ2H 1NJIJ 3CCLH 1Y69K 1VQ9H 1YHQH 2ZJPJ 5GADN 1VQNH 1Q81J 1KD1J 1VQ7H 1YITH 3OW2H 1YJWH 1S72H 3J7ZM 3CPWH 4WCEJ 1W2BH 1M1KJ 2ZJRJ 1K73J 3CC2H 1KC8J 3PIOJ 3CCQH 3PIPJ 1K8AJ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JVG J;  2ZJQ J;  4WFB J;  5DM6 J;  4WFA J;  5DM7 J;  2QA4 H;  1Q86 J;  5GAH N;  5JVH J;  1Q82 J;  2QEX H;  3CD6 H;  1VQ4 H;  3CCV H;  3CF5 J;  3CMA H;  1VQ6 H;  1VQM H;  3CCE H;  3CCM H;  1YJN H;  1VQK H;  5AN9 F;  5HL7 J;  4WF9 J;  5GAG N;  1K9M J;  1YI2 H;  3DLL J;  4IOA J;  3CC4 H;  3CCS H;  1VQ8 H;  1VQO H;  1WKI A;  2OTJ H;  1VQL H;  1VQP H;  2PA2 A;  3CME H;  1M90 J;  4UY8 M;  4WFN J;  1VQ5 H;  3CCR H;  4U67 J;  1Q7Y J;  5GAE N;  3G71 H;  3I56 H;  5H1S O;  1YIJ H;  1QVF H;  3I55 H;  1N8R J;  1QVG H;  2OTL H;  4IO9 J;  5MLC O;  3G4S H;  1YJ9 H;  3G6E H;  4IOC J;  3CXC H;  3CC7 H;  1KQS H;  3CCU H;  3CCJ H;  1JJ2 H;  1NJI J;  3CCL H;  1Y69 K;  1VQ9 H;  1YHQ H;  2ZJP J;  5GAD N;  1VQN H;  1Q81 J;  1KD1 J;  1VQ7 H;  1YIT H;  3OW2 H;  1YJW H;  1S72 H;  3J7Z M;  3CPW H;  4WCE J;  1W2B H;  1M1K J;  2ZJR J;  1K73 J;  3CC2 H;  1KC8 J;  3PIO J;  3CCQ H;  3PIP J;  1K8A J; 
#chains in the Genus database with same CATH topology
 5AYY A;  5JVG J;  2ZJQ J;  3C2R A;  4WFB J;  5DM6 J;  1FIQ C;  1SB3 A;  3L4P A;  5DM7 J;  4WFA J;  3C2F A;  2QA4 H;  1Q86 J;  5GAH N;  5JVH J;  1Q82 J;  2QEX H;  1JRP B;  3CD6 H;  1VQ4 H;  3CCV H;  1O4U A;  3CF5 J;  5EY3 A;  1VDV A;  3H5Q A;  1N63 B;  1NVI E;  3B9J C;  3CMA H;  1VQ6 H;  1YTD A;  1VQM H;  1FFV B;  5HUO A;  2Q5W E;  3WO0 A;  1SIJ A;  1WYG A;  3CCE H;  3CCM H;  1YJN H;  1VQK H;  5AN9 F;  5HL7 J;  4AP8 A;  4WF9 J;  3AM9 A;  3EUB 4;  2I14 A;  2W3S B;  1YTK A;  4KWW A;  4C7Z A;  5GAG N;  1K9M J;  1BRW A;  4YYY A;  1YI2 H;  3C2E A;  1FMA E;  1N61 B;  4US9 A;  3DLL J;  4IOA J;  1N62 B;  3CC4 H;  3CCS H;  1VQ8 H;  1DGJ A;  1VQO H;  2WK6 A;  4US8 A;  3C2O A;  1WKI A;  3NVY C;  5AYX A;  1OTP A;  3WNZ A;  2OTJ H;  4EAF A;  3AMZ A;  1VQL H;  4USA A;  2W55 B;  1RM6 A;  1QAP A;  3NRZ C;  3VMM A;  1VQP H;  1N5W B;  2B7P A;  5HUL A;  4YEK A;  2PA2 A;  3CME H;  1X1O A;  2QIE A;  1QPQ A;  1M90 J;  4UY8 M;  4WFN J;  3C2V A;  4KWV A;  1VQ5 H;  1N60 B;  1JRO B;  2E3T A;  3CCR H;  4U67 J;  1VLB A;  3NVV C;  1Q7Y J;  5GAE N;  5HUP A;  1FFU B;  3G71 H;  3I56 H;  5H1S O;  1YIJ H;  2WK5 A;  1QVF H;  4LHM A;  2B7N A;  1QPO A;  3FAH A;  3I55 H;  1N8R J;  1NVJ A;  1QVG H;  2W54 B;  2OTL H;  4IO9 J;  1ZXI B;  5MLC O;  3G4S H;  1YJ9 H;  3G6E H;  4IOC J;  3CXC H;  3CC7 H;  1KQS H;  3CCU H;  5EP8 A;  3CCJ H;  1N5X A;  1JJ2 H;  3NVW C;  1NJI J;  3CCL H;  1Y69 K;  4C80 A;  1FO4 A;  3WO1 A;  3L0G A;  1YTE A;  1VQ9 H;  3NS1 C;  3RPF A;  1QPN A;  4GA5 A;  2DSJ A;  1YHQ H;  5AYZ A;  3BII E;  2ZJP J;  4X46 A;  5GAD N;  1Q81 J;  4GA4 A;  1VQN H;  1KD1 J;  1VQ7 H;  1V97 A;  1YIT H;  1FM0 E;  2J0F A;  3GNN A;  1AZY A;  1QPR A;  3OW2 H;  1YJW H;  1S72 H;  3J7Z M;  4I9A A;  2OMD A;  3CPW H;  4ZOH A;  2W3R B;  2WP4 A;  2JBM A;  2I1O A;  1UOU A;  4XR5 A;  3SR6 C;  4WCE J;  3AN1 A;  1W2B H;  1M1K J;  2ZJR J;  5MPO C;  1K73 J;  3TQV A;  3CC2 H;  3ETR C;  2TPT A;  4GA6 A;  1KC8 J;  3FC4 A;  3NVZ C;  3PIO J;  3PAJ A;  4EAD A;  3CCQ H;  2B7Q A;  4C7Y A;  3PIP J;  1K8A J; 
#chains in the Genus database with same CATH homology
 5JVG J;  2ZJQ J;  4WFB J;  5DM6 J;  4WFA J;  5DM7 J;  2QA4 H;  1Q86 J;  5GAH N;  5JVH J;  1Q82 J;  2QEX H;  3CD6 H;  1VQ4 H;  3CCV H;  3CF5 J;  3CMA H;  1VQ6 H;  1VQM H;  3CCE H;  3CCM H;  1YJN H;  1VQK H;  5AN9 F;  5HL7 J;  4WF9 J;  5GAG N;  1K9M J;  1YI2 H;  3DLL J;  4IOA J;  3CC4 H;  3CCS H;  1VQ8 H;  1VQO H;  1WKI A;  2OTJ H;  1VQL H;  1VQP H;  2PA2 A;  3CME H;  1M90 J;  4UY8 M;  4WFN J;  1VQ5 H;  3CCR H;  4U67 J;  1Q7Y J;  5GAE N;  3G71 H;  3I56 H;  5H1S O;  1YIJ H;  1QVF H;  3I55 H;  1N8R J;  1QVG H;  2OTL H;  4IO9 J;  5MLC O;  3G4S H;  1YJ9 H;  3G6E H;  4IOC J;  3CXC H;  3CC7 H;  1KQS H;  3CCU H;  3CCJ H;  1JJ2 H;  1NJI J;  3CCL H;  1Y69 K;  1VQ9 H;  1YHQ H;  2ZJP J;  5GAD N;  1VQN H;  1Q81 J;  1KD1 J;  1VQ7 H;  1YIT H;  3OW2 H;  1YJW H;  1S72 H;  3J7Z M;  3CPW H;  4WCE J;  1W2B H;  1M1K J;  2ZJR J;  1K73 J;  3CC2 H;  1KC8 J;  3PIO J;  3CCQ H;  3PIP J;  1K8A J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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