1YJNH

Crystal structure of clindamycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 37
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2005-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1yjnH00
3CCVH 1VQ8H 1YJWH 1VQ6H 5AN9F 1QVFH 1VQMH 3CC2H 4UY8M 2QA4H 1VQKH 1Q82J 5JVHJ 5MLCO 4U67J 1YITH 1QVGH 4WCEJ 1K8AJ 1Y69K 5DM7J 3PIOJ 3CCEH 3PIPJ 3CXCH 3CCUH 2OTJH 1M1KJ 1VQPH 1VQOH 1VQ4H 3CC7H 5JVGJ 1NJIJ 4WFBJ 1Q81J 3J7ZM 1Q86J 1W2BH 5GADN 1YHQH 4WF9J 1JJ2H 5GAHN 5H1SO 5GAEN 1VQNH 3CF5J 4IOCJ 2PA2A 2ZJQJ 1VQ9H 2ZJPJ 3CCMH 5GAGN 1VQ5H 1K9MJ 3G71H 3DLLJ 1VQLH 1YJNH 4WFNJ 3CCQH 3CCSH 3CPWH 1N8RJ 1YIJH 3I56H 1KD1J 1WKIA 2ZJRJ 2QEXH 2OTLH 1K73J 3CCLH 3G6EH 1M90J 3CMEH 1KQSH 3I55H 3G4SH 5HL7J 1VQ7H 1S72H 1YI2H 1YJ9H 5DM6J 3CCRH 1KC8J 4IOAJ 3CC4H 3OW2H 3CCJH 4WFAJ 4IO9J 1Q7YJ 3CMAH 3CD6H
chains in the Genus database with same CATH superfamily
3AM9A 3BIIE 1JROB 1N5WB 3CCVH 1VQ8H 1YJWH 4I9AA 1N5XA 1VQ6H 3RPFA 3C2EA 2WK6A 2J0FA 5AN9F 5AYYA 4LHMA 1QVFH 4C7YA 1VQMH 3CC2H 5MPOC 4UY8M 4EAFA 2QA4H 1VQKH 1OTPA 3NS1C 1FFUB 2E3TA 5JVHJ 1Q82J 1UOUA 1VDVA 1WYGA 3C2FA 5MLCO 4U67J 2Q5WE 1YITH 3C2RA 1QVGH 4WCEJ 3FC4A 1YTKA 1K8AJ 3AN1A 5DM7J 1Y69K 3PIOJ 1X1OA 3CCEH 3PIPJ 3CXCH 3B9JC 3CCUH 2OTJH 1N63B 3TQVA 1VQPH 1M1KJ 1VQOH 2DSJA 1VQ4H 3CC7H 2W3SB 5AYXA 1QAPA 3ETRC 5JVGJ 3SR6C 1NJIJ 4WFBJ 2WP4A 1Q81J 1AZYA 1QPQA 1YTEA 3J7ZM 1Q86J 1W2BH 3AMZA 5GADN 4US8A 1YHQH 3WNZA 1N62B 4WF9J 1JJ2H 2W55B 5GAHN 2OMDA 1FMAE 5H1SO 5GAEN 4GA6A 1VQNH 3VMMA 3CF5J 1RM6A 4GA5A 1FO4A 1ZXIB 4IOCJ 2PA2A 4KWWA 4EADA 3PAJA 1FFVB 2ZJQJ 1VQ9H 1YTDA 1VLBA 2ZJPJ 3C2VA 4KWVA 2JBMA 5HULA 1FM0E 4C80A 1SIJA 4US9A 3CCMH 5GAGN 1N60B 5HUPA 1VQ5H 1FIQC 1O4UA 1K9MJ 1BRWA 3G71H 3DLLJ 4XR5A 2QIEA 1VQLH 1YJNH 2B7NA 4WFNJ 3CCQH 3NVWC 3CCSH 2I1OA 4USAA 3CPWH 3NVYC 1QPRA 4GA4A 1N8RJ 5EP8A 1YIJH 5AYZA 1N61B 3I56H 2TPTA 1KD1J 1WKIA 3C2OA 1QPNA 2ZJRJ 2QEXH 2OTLH 1NVIE 2B7QA 3CCLH 1K73J 3G6EH 1JRPB 2I14A 3L0GA 1M90J 3CMEH 1NVJA 1KQSH 4X46A 3H5QA 5HUOA 1DGJA 5EY3A 2W3RB 3I55H 3G4SH 5HL7J 4AP8A 1VQ7H 1S72H 1SB3A 3NVZC 1YI2H 3FAHA 3L4PA 3GNNA 2WK5A 4ZOHA 4YEKA 2B7PA 5DM6J 3CCRH 1YJ9H 1KC8J 4IOAJ 3EUB4 3CC4H 3OW2H 4YYYA 3WO1A 2W54B 1QPOA 3CCJH 3NVVC 1V97A 4C7ZA 4WFAJ 4IO9J 1Q7YJ 3CMAH 3NRZC 3WO0A 3CD6H
chains in the Genus database with same CATH topology
3CCVH 1VQ8H 1YJWH 1VQ6H 5AN9F 1QVFH 1VQMH 3CC2H 4UY8M 2QA4H 1VQKH 1Q82J 5JVHJ 5MLCO 4U67J 1YITH 1QVGH 4WCEJ 1K8AJ 1Y69K 5DM7J 3PIOJ 3CCEH 3PIPJ 3CXCH 3CCUH 2OTJH 1M1KJ 1VQPH 1VQOH 1VQ4H 3CC7H 5JVGJ 1NJIJ 4WFBJ 1Q81J 3J7ZM 1Q86J 1W2BH 5GADN 1YHQH 4WF9J 1JJ2H 5GAHN 5H1SO 5GAEN 1VQNH 3CF5J 4IOCJ 2PA2A 2ZJQJ 1VQ9H 2ZJPJ 3CCMH 5GAGN 1VQ5H 1K9MJ 3G71H 3DLLJ 1VQLH 1YJNH 4WFNJ 3CCQH 3CCSH 3CPWH 1N8RJ 1YIJH 3I56H 1KD1J 1WKIA 2ZJRJ 2QEXH 2OTLH 1K73J 3CCLH 3G6EH 1M90J 3CMEH 1KQSH 3I55H 3G4SH 5HL7J 1VQ7H 1S72H 1YI2H 1YJ9H 5DM6J 3CCRH 1KC8J 4IOAJ 3CC4H 3OW2H 3CCJH 4WFAJ 4IO9J 1Q7YJ 3CMAH 3CD6H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCV H;  1VQ8 H;  1YJW H;  1VQ6 H;  5AN9 F;  1QVF H;  1VQM H;  3CC2 H;  4UY8 M;  2QA4 H;  1VQK H;  1Q82 J;  5JVH J;  5MLC O;  4U67 J;  1YIT H;  1QVG H;  4WCE J;  1K8A J;  1Y69 K;  5DM7 J;  3PIO J;  3CCE H;  3PIP J;  3CXC H;  3CCU H;  2OTJ H;  1M1K J;  1VQP H;  1VQO H;  1VQ4 H;  3CC7 H;  5JVG J;  1NJI J;  4WFB J;  1Q81 J;  3J7Z M;  1Q86 J;  1W2B H;  5GAD N;  1YHQ H;  4WF9 J;  1JJ2 H;  5GAH N;  5H1S O;  5GAE N;  1VQN H;  3CF5 J;  4IOC J;  2PA2 A;  2ZJQ J;  1VQ9 H;  2ZJP J;  3CCM H;  5GAG N;  1VQ5 H;  1K9M J;  3G71 H;  3DLL J;  1VQL H;  1YJN H;  4WFN J;  3CCQ H;  3CCS H;  3CPW H;  1N8R J;  1YIJ H;  3I56 H;  1KD1 J;  1WKI A;  2ZJR J;  2QEX H;  2OTL H;  1K73 J;  3CCL H;  3G6E H;  1M90 J;  3CME H;  1KQS H;  3I55 H;  3G4S H;  5HL7 J;  1VQ7 H;  1S72 H;  1YI2 H;  1YJ9 H;  5DM6 J;  3CCR H;  1KC8 J;  4IOA J;  3CC4 H;  3OW2 H;  3CCJ H;  4WFA J;  4IO9 J;  1Q7Y J;  3CMA H;  3CD6 H; 
#chains in the Genus database with same CATH topology
 3AM9 A;  3BII E;  1JRO B;  1N5W B;  3CCV H;  1VQ8 H;  1YJW H;  4I9A A;  1N5X A;  1VQ6 H;  3RPF A;  3C2E A;  2WK6 A;  2J0F A;  5AN9 F;  5AYY A;  4LHM A;  1QVF H;  4C7Y A;  1VQM H;  3CC2 H;  5MPO C;  4UY8 M;  4EAF A;  2QA4 H;  1VQK H;  1OTP A;  3NS1 C;  1FFU B;  2E3T A;  5JVH J;  1Q82 J;  1UOU A;  1VDV A;  1WYG A;  3C2F A;  5MLC O;  4U67 J;  2Q5W E;  1YIT H;  3C2R A;  1QVG H;  4WCE J;  3FC4 A;  1YTK A;  1K8A J;  3AN1 A;  5DM7 J;  1Y69 K;  3PIO J;  1X1O A;  3CCE H;  3PIP J;  3CXC H;  3B9J C;  3CCU H;  2OTJ H;  1N63 B;  3TQV A;  1VQP H;  1M1K J;  1VQO H;  2DSJ A;  1VQ4 H;  3CC7 H;  2W3S B;  5AYX A;  1QAP A;  3ETR C;  5JVG J;  3SR6 C;  1NJI J;  4WFB J;  2WP4 A;  1Q81 J;  1AZY A;  1QPQ A;  1YTE A;  3J7Z M;  1Q86 J;  1W2B H;  3AMZ A;  5GAD N;  4US8 A;  1YHQ H;  3WNZ A;  1N62 B;  4WF9 J;  1JJ2 H;  2W55 B;  5GAH N;  2OMD A;  1FMA E;  5H1S O;  5GAE N;  4GA6 A;  1VQN H;  3VMM A;  3CF5 J;  1RM6 A;  4GA5 A;  1FO4 A;  1ZXI B;  4IOC J;  2PA2 A;  4KWW A;  4EAD A;  3PAJ A;  1FFV B;  2ZJQ J;  1VQ9 H;  1YTD A;  1VLB A;  2ZJP J;  3C2V A;  4KWV A;  2JBM A;  5HUL A;  1FM0 E;  4C80 A;  1SIJ A;  4US9 A;  3CCM H;  5GAG N;  1N60 B;  5HUP A;  1VQ5 H;  1FIQ C;  1O4U A;  1K9M J;  1BRW A;  3G71 H;  3DLL J;  4XR5 A;  2QIE A;  1VQL H;  1YJN H;  2B7N A;  4WFN J;  3CCQ H;  3NVW C;  3CCS H;  2I1O A;  4USA A;  3CPW H;  3NVY C;  1QPR A;  4GA4 A;  1N8R J;  5EP8 A;  1YIJ H;  5AYZ A;  1N61 B;  3I56 H;  2TPT A;  1KD1 J;  1WKI A;  3C2O A;  1QPN A;  2ZJR J;  2QEX H;  2OTL H;  1NVI E;  2B7Q A;  3CCL H;  1K73 J;  3G6E H;  1JRP B;  2I14 A;  3L0G A;  1M90 J;  3CME H;  1NVJ A;  1KQS H;  4X46 A;  3H5Q A;  5HUO A;  1DGJ A;  5EY3 A;  2W3R B;  3I55 H;  3G4S H;  5HL7 J;  4AP8 A;  1VQ7 H;  1S72 H;  1SB3 A;  3NVZ C;  1YI2 H;  3FAH A;  3L4P A;  3GNN A;  2WK5 A;  4ZOH A;  4YEK A;  2B7P A;  5DM6 J;  3CCR H;  1YJ9 H;  1KC8 J;  4IOA J;  3EUB 4;  3CC4 H;  3OW2 H;  4YYY A;  3WO1 A;  2W54 B;  1QPO A;  3CCJ H;  3NVV C;  1V97 A;  4C7Z A;  4WFA J;  4IO9 J;  1Q7Y J;  3CMA H;  3NRZ C;  3WO0 A;  3CD6 H; 
#chains in the Genus database with same CATH homology
 3CCV H;  1VQ8 H;  1YJW H;  1VQ6 H;  5AN9 F;  1QVF H;  1VQM H;  3CC2 H;  4UY8 M;  2QA4 H;  1VQK H;  1Q82 J;  5JVH J;  5MLC O;  4U67 J;  1YIT H;  1QVG H;  4WCE J;  1K8A J;  1Y69 K;  5DM7 J;  3PIO J;  3CCE H;  3PIP J;  3CXC H;  3CCU H;  2OTJ H;  1M1K J;  1VQP H;  1VQO H;  1VQ4 H;  3CC7 H;  5JVG J;  1NJI J;  4WFB J;  1Q81 J;  3J7Z M;  1Q86 J;  1W2B H;  5GAD N;  1YHQ H;  4WF9 J;  1JJ2 H;  5GAH N;  5H1S O;  5GAE N;  1VQN H;  3CF5 J;  4IOC J;  2PA2 A;  2ZJQ J;  1VQ9 H;  2ZJP J;  3CCM H;  5GAG N;  1VQ5 H;  1K9M J;  3G71 H;  3DLL J;  1VQL H;  1YJN H;  4WFN J;  3CCQ H;  3CCS H;  3CPW H;  1N8R J;  1YIJ H;  3I56 H;  1KD1 J;  1WKI A;  2ZJR J;  2QEX H;  2OTL H;  1K73 J;  3CCL H;  3G6E H;  1M90 J;  3CME H;  1KQS H;  3I55 H;  3G4S H;  5HL7 J;  1VQ7 H;  1S72 H;  1YI2 H;  1YJ9 H;  5DM6 J;  3CCR H;  1KC8 J;  4IOA J;  3CC4 H;  3OW2 H;  3CCJ H;  4WFA J;  4IO9 J;  1Q7Y J;  3CMA H;  3CD6 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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