1YJWH

Crystal structure of quinupristin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords 23S RIBOSOMAL RNA
total genus 38
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2005-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 1yjwH00
1VQLH 4WFAJ 1VQ8H 1W2BH 4IO9J 4WFNJ 5GAGN 3CCLH 1QVGH 4WCEJ 3CF5J 3PIPJ 3OW2H 1KD1J 2ZJRJ 3CCUH 1S72H 3CC7H 5GADN 5AN9F 1VQOH 3I55H 3CMEH 1VQMH 1YJNH 3CMAH 3CCEH 3CCJH 4UY8M 1Y69K 4U67J 1K8AJ 2QA4H 5H1SO 3PIOJ 2PA2A 3CPWH 1Q86J 1VQKH 1Q7YJ 1JJ2H 1KC8J 5GAHN 4WFBJ 1VQPH 1VQ7H 3CCSH 1VQ9H 3CCMH 5MLCO 1YI2H 3CD6H 1VQ5H 1QVFH 3G6EH 1KQSH 2QEXH 1N8RJ 1YHQH 1K73J 4WF9J 3CC2H 5DM6J 3J7ZM 3CCVH 5JVGJ 1VQNH 1K9MJ 4IOCJ 3CXCH 2OTLH 1Q81J 3G4SH 5GAEN 5DM7J 3CCRH 1YJWH 3DLLJ 3CCQH 4IOAJ 1YIJH 2ZJPJ 3CC4H 1NJIJ 3I56H 1WKIA 1M1KJ 1YITH 2ZJQJ 5JVHJ 3G71H 1VQ4H 1Q82J 1VQ6H 2OTJH 1M90J 1YJ9H 5HL7J
chains in the Genus database with same CATH superfamily
5MPOC 4YYYA 5HUOA 1VQLH 4WFAJ 1X1OA 1VQ8H 2B7QA 4C7ZA 2DSJA 1W2BH 4IO9J 4WFNJ 5GAGN 1V97A 3CCLH 1N5WB 1QPNA 5EY3A 2Q5WE 1QVGH 5AYZA 2B7NA 2I1OA 4WCEJ 2I14A 3PAJA 3CF5J 2W55B 2W3SB 3PIPJ 1JROB 3OW2H 1KD1J 3CCUH 2ZJRJ 3NVWC 1S72H 3BIIE 3CC7H 1WYGA 3FC4A 1N60B 5GADN 1BRWA 4I9AA 4GA4A 3NVYC 5AN9F 1VQOH 3NS1C 1N62B 1RM6A 3I55H 3CMEH 1VQMH 4EAFA 1YJNH 3CMAH 3CCEH 3CCJH 1AZYA 3AMZA 3C2EA 4UY8M 4LHMA 1NVJA 1Y69K 4U67J 1FM0E 4C7YA 3B9JC 4KWWA 1K8AJ 1NVIE 1QPOA 5H1SO 3PIOJ 2QA4H 2PA2A 2J0FA 1QPQA 1O4UA 2W3RB 3WO1A 3CPWH 1Q86J 1FFVB 3C2OA 1VQKH 1Q7YJ 4EADA 2TPTA 2QIEA 1JJ2H 4US8A 1KC8J 5GAHN 4WFBJ 1VQPH 1VQ7H 3CCSH 1VQ9H 3NVZC 4C80A 1SB3A 1YTEA 3AM9A 3ETRC 1FIQC 5MLCO 3CCMH 1FO4A 1YI2H 3CD6H 4XR5A 1VQ5H 1QVFH 4ZOHA 3G6EH 1KQSH 3TQVA 4GA5A 2WP4A 4USAA 1YTDA 1N63B 2QEXH 3NRZC 1N8RJ 1YHQH 3L4PA 1K73J 1FMAE 3C2FA 3WO0A 4WF9J 3CC2H 5DM6J 3J7ZM 3C2RA 1N61B 4X46A 3CCVH 3VMMA 5JVGJ 4IOAJ 1VQNH 2E3TA 1K9MJ 4IOCJ 1VDVA 3CXCH 3H5QA 3EUB4 3L0GA 4YEKA 2OTLH 1Q81J 1YTKA 3WNZA 1QPRA 4AP8A 3G4SH 1UOUA 5GAEN 5DM7J 3CCRH 2WK5A 1YJWH 3CCQH 3NVVC 3DLLJ 2WK6A 3SR6C 2ZJPJ 1QAPA 3RPFA 1YIJH 3C2VA 5AYYA 2OMDA 2B7PA 3CC4H 3GNNA 1NJIJ 4KWVA 3I56H 1WKIA 1M1KJ 1VLBA 1DGJA 1OTPA 1YITH 4US9A 1ZXIB 1JRPB 2ZJQJ 2JBMA 4GA6A 5JVHJ 5AYXA 1FFUB 3G71H 1VQ4H 1Q82J 1N5XA 2W54B 5HULA 5HUPA 1SIJA 1VQ6H 2OTJH 1M90J 3AN1A 3FAHA 5EP8A 1YJ9H 5HL7J
chains in the Genus database with same CATH topology
1VQLH 4WFAJ 1VQ8H 1W2BH 4IO9J 4WFNJ 5GAGN 3CCLH 1QVGH 4WCEJ 3CF5J 3PIPJ 3OW2H 1KD1J 2ZJRJ 3CCUH 1S72H 3CC7H 5GADN 5AN9F 1VQOH 3I55H 3CMEH 1VQMH 1YJNH 3CMAH 3CCEH 3CCJH 4UY8M 1Y69K 4U67J 1K8AJ 2QA4H 5H1SO 3PIOJ 2PA2A 3CPWH 1Q86J 1VQKH 1Q7YJ 1JJ2H 1KC8J 5GAHN 4WFBJ 1VQPH 1VQ7H 3CCSH 1VQ9H 3CCMH 5MLCO 1YI2H 3CD6H 1VQ5H 1QVFH 3G6EH 1KQSH 2QEXH 1N8RJ 1YHQH 1K73J 4WF9J 3CC2H 5DM6J 3J7ZM 3CCVH 5JVGJ 1VQNH 1K9MJ 4IOCJ 3CXCH 2OTLH 1Q81J 3G4SH 5GAEN 5DM7J 3CCRH 1YJWH 3DLLJ 3CCQH 4IOAJ 1YIJH 2ZJPJ 3CC4H 1NJIJ 3I56H 1WKIA 1M1KJ 1YITH 2ZJQJ 5JVHJ 3G71H 1VQ4H 1Q82J 1VQ6H 2OTJH 1M90J 1YJ9H 5HL7J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQL H;  4WFA J;  1VQ8 H;  1W2B H;  4IO9 J;  4WFN J;  5GAG N;  3CCL H;  1QVG H;  4WCE J;  3CF5 J;  3PIP J;  3OW2 H;  1KD1 J;  2ZJR J;  3CCU H;  1S72 H;  3CC7 H;  5GAD N;  5AN9 F;  1VQO H;  3I55 H;  3CME H;  1VQM H;  1YJN H;  3CMA H;  3CCE H;  3CCJ H;  4UY8 M;  1Y69 K;  4U67 J;  1K8A J;  2QA4 H;  5H1S O;  3PIO J;  2PA2 A;  3CPW H;  1Q86 J;  1VQK H;  1Q7Y J;  1JJ2 H;  1KC8 J;  5GAH N;  4WFB J;  1VQP H;  1VQ7 H;  3CCS H;  1VQ9 H;  3CCM H;  5MLC O;  1YI2 H;  3CD6 H;  1VQ5 H;  1QVF H;  3G6E H;  1KQS H;  2QEX H;  1N8R J;  1YHQ H;  1K73 J;  4WF9 J;  3CC2 H;  5DM6 J;  3J7Z M;  3CCV H;  5JVG J;  1VQN H;  1K9M J;  4IOC J;  3CXC H;  2OTL H;  1Q81 J;  3G4S H;  5GAE N;  5DM7 J;  3CCR H;  1YJW H;  3DLL J;  3CCQ H;  4IOA J;  1YIJ H;  2ZJP J;  3CC4 H;  1NJI J;  3I56 H;  1WKI A;  1M1K J;  1YIT H;  2ZJQ J;  5JVH J;  3G71 H;  1VQ4 H;  1Q82 J;  1VQ6 H;  2OTJ H;  1M90 J;  1YJ9 H;  5HL7 J; 
#chains in the Genus database with same CATH topology
 5MPO C;  4YYY A;  5HUO A;  1VQL H;  4WFA J;  1X1O A;  1VQ8 H;  2B7Q A;  4C7Z A;  2DSJ A;  1W2B H;  4IO9 J;  4WFN J;  5GAG N;  1V97 A;  3CCL H;  1N5W B;  1QPN A;  5EY3 A;  2Q5W E;  1QVG H;  5AYZ A;  2B7N A;  2I1O A;  4WCE J;  2I14 A;  3PAJ A;  3CF5 J;  2W55 B;  2W3S B;  3PIP J;  1JRO B;  3OW2 H;  1KD1 J;  3CCU H;  2ZJR J;  3NVW C;  1S72 H;  3BII E;  3CC7 H;  1WYG A;  3FC4 A;  1N60 B;  5GAD N;  1BRW A;  4I9A A;  4GA4 A;  3NVY C;  5AN9 F;  1VQO H;  3NS1 C;  1N62 B;  1RM6 A;  3I55 H;  3CME H;  1VQM H;  4EAF A;  1YJN H;  3CMA H;  3CCE H;  3CCJ H;  1AZY A;  3AMZ A;  3C2E A;  4UY8 M;  4LHM A;  1NVJ A;  1Y69 K;  4U67 J;  1FM0 E;  4C7Y A;  3B9J C;  4KWW A;  1K8A J;  1NVI E;  1QPO A;  5H1S O;  3PIO J;  2QA4 H;  2PA2 A;  2J0F A;  1QPQ A;  1O4U A;  2W3R B;  3WO1 A;  3CPW H;  1Q86 J;  1FFV B;  3C2O A;  1VQK H;  1Q7Y J;  4EAD A;  2TPT A;  2QIE A;  1JJ2 H;  4US8 A;  1KC8 J;  5GAH N;  4WFB J;  1VQP H;  1VQ7 H;  3CCS H;  1VQ9 H;  3NVZ C;  4C80 A;  1SB3 A;  1YTE A;  3AM9 A;  3ETR C;  1FIQ C;  5MLC O;  3CCM H;  1FO4 A;  1YI2 H;  3CD6 H;  4XR5 A;  1VQ5 H;  1QVF H;  4ZOH A;  3G6E H;  1KQS H;  3TQV A;  4GA5 A;  2WP4 A;  4USA A;  1YTD A;  1N63 B;  2QEX H;  3NRZ C;  1N8R J;  1YHQ H;  3L4P A;  1K73 J;  1FMA E;  3C2F A;  3WO0 A;  4WF9 J;  3CC2 H;  5DM6 J;  3J7Z M;  3C2R A;  1N61 B;  4X46 A;  3CCV H;  3VMM A;  5JVG J;  4IOA J;  1VQN H;  2E3T A;  1K9M J;  4IOC J;  1VDV A;  3CXC H;  3H5Q A;  3EUB 4;  3L0G A;  4YEK A;  2OTL H;  1Q81 J;  1YTK A;  3WNZ A;  1QPR A;  4AP8 A;  3G4S H;  1UOU A;  5GAE N;  5DM7 J;  3CCR H;  2WK5 A;  1YJW H;  3CCQ H;  3NVV C;  3DLL J;  2WK6 A;  3SR6 C;  2ZJP J;  1QAP A;  3RPF A;  1YIJ H;  3C2V A;  5AYY A;  2OMD A;  2B7P A;  3CC4 H;  3GNN A;  1NJI J;  4KWV A;  3I56 H;  1WKI A;  1M1K J;  1VLB A;  1DGJ A;  1OTP A;  1YIT H;  4US9 A;  1ZXI B;  1JRP B;  2ZJQ J;  2JBM A;  4GA6 A;  5JVH J;  5AYX A;  1FFU B;  3G71 H;  1VQ4 H;  1Q82 J;  1N5X A;  2W54 B;  5HUL A;  5HUP A;  1SIJ A;  1VQ6 H;  2OTJ H;  1M90 J;  3AN1 A;  3FAH A;  5EP8 A;  1YJ9 H;  5HL7 J; 
#chains in the Genus database with same CATH homology
 1VQL H;  4WFA J;  1VQ8 H;  1W2B H;  4IO9 J;  4WFN J;  5GAG N;  3CCL H;  1QVG H;  4WCE J;  3CF5 J;  3PIP J;  3OW2 H;  1KD1 J;  2ZJR J;  3CCU H;  1S72 H;  3CC7 H;  5GAD N;  5AN9 F;  1VQO H;  3I55 H;  3CME H;  1VQM H;  1YJN H;  3CMA H;  3CCE H;  3CCJ H;  4UY8 M;  1Y69 K;  4U67 J;  1K8A J;  2QA4 H;  5H1S O;  3PIO J;  2PA2 A;  3CPW H;  1Q86 J;  1VQK H;  1Q7Y J;  1JJ2 H;  1KC8 J;  5GAH N;  4WFB J;  1VQP H;  1VQ7 H;  3CCS H;  1VQ9 H;  3CCM H;  5MLC O;  1YI2 H;  3CD6 H;  1VQ5 H;  1QVF H;  3G6E H;  1KQS H;  2QEX H;  1N8R J;  1YHQ H;  1K73 J;  4WF9 J;  3CC2 H;  5DM6 J;  3J7Z M;  3CCV H;  5JVG J;  1VQN H;  1K9M J;  4IOC J;  3CXC H;  2OTL H;  1Q81 J;  3G4S H;  5GAE N;  5DM7 J;  3CCR H;  1YJW H;  3DLL J;  3CCQ H;  4IOA J;  1YIJ H;  2ZJP J;  3CC4 H;  1NJI J;  3I56 H;  1WKI A;  1M1K J;  1YIT H;  2ZJQ J;  5JVH J;  3G71 H;  1VQ4 H;  1Q82 J;  1VQ6 H;  2OTJ H;  1M90 J;  1YJ9 H;  5HL7 J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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