2QEXH

Negamycin binds to the wall of the nascent chain exit tunnel of the 50s ribosomal subunit
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIDSSPAGNA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 35
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 2qexH00
1KC8J 1VQ9H 1W2BH 1KD1J 1QVFH 1YJ9H 3CCRH 3PIPJ 1M90J 5GAHN 3CPWH 3CD6H 3PIOJ 3CXCH 3CC7H 5AN9F 1Y69K 1VQNH 1YI2H 1Q7YJ 1KQSH 4IO9J 2ZJRJ 1VQ5H 3CCJH 1VQ4H 1K8AJ 1K9MJ 1M1KJ 3CCMH 1Q81J 3J7ZM 1VQPH 1VQMH 1YJWH 3CCVH 1S72H 1Q82J 1YJNH 5DM6J 2PA2A 1K73J 5GAGN 1VQLH 2ZJPJ 3CMAH 4WCEJ 3CMEH 3CC2H 3CCEH 3CCSH 4U67J 3G71H 3CCQH 4IOCJ 1N8RJ 3CCLH 1JJ2H 2OTJH 3CCUH 4WFAJ 1VQ7H 2ZJQJ 1YHQH 3DLLJ 1VQ6H 4WFBJ 1YITH 3G4SH 1WKIA 3OW2H 1NJIJ 4IOAJ 5MLCO 4UY8M 3CC4H 4WF9J 2OTLH 5H1SO 5GADN 3I56H 5JVHJ 1YIJH 5JVGJ 1Q86J 4WFNJ 5HL7J 1VQOH 5DM7J 1QVGH 1VQKH 5GAEN 1VQ8H 3G6EH 3I55H 2QEXH 2QA4H 3CF5J
chains in the Genus database with same CATH superfamily
2E3TA 1FFUB 2TPTA 3L4PA 1KC8J 1VQ9H 1NVJA 5EP8A 1N61B 1ZXIB 1W2BH 1KD1J 4C7ZA 1QVFH 3FC4A 3L0GA 1YJ9H 3C2VA 3B9JC 3CCRH 1SB3A 3PIPJ 1N63B 5GAHN 4GA6A 1M90J 3AMZA 3CPWH 3PIOJ 3CD6H 3CXCH 3CC7H 5AN9F 1Y69K 1VQNH 1QPOA 3GNNA 1VLBA 1YTDA 1YI2H 1Q7YJ 1KQSH 1N5WB 1N62B 4IO9J 2ZJRJ 1VQ5H 3CCJH 1VQ4H 1FMAE 1K8AJ 1K9MJ 1M1KJ 3NRZC 3WNZA 5MPOC 3CCMH 2WK5A 2W55B 1Q81J 3J7ZM 4XR5A 3NVZC 3TQVA 1VQPH 1SIJA 1VQMH 2QIEA 1YJWH 2I14A 5HULA 3AM9A 2W54B 3SR6C 3C2FA 1FO4A 3CCVH 1S72H 1Q82J 1O4UA 2J0FA 5DM6J 3RPFA 1YJNH 1AZYA 2PA2A 2Q5WE 4GA5A 4YEKA 3PAJA 1K73J 5GAGN 1VQLH 5EY3A 4AP8A 2ZJPJ 3CMAH 1FFVB 4WCEJ 3CMEH 4US8A 1N60B 3WO1A 3CC2H 1QAPA 5AYYA 3CCEH 2OMDA 2W3RB 5AYZA 1V97A 3NVWC 1QPQA 4U67J 3G71H 3CCSH 2W3SB 1FM0E 5HUOA 4KWWA 3CCQH 4IOCJ 3NVYC 1N8RJ 3CCLH 2WK6A 1OTPA 1JJ2H 1X1OA 3EUB4 2OTJH 3WO0A 3FAHA 3CCUH 1BRWA 4WFAJ 1VQ7H 4GA4A 2ZJQJ 2I1OA 1VDVA 1YHQH 3DLLJ 1VQ6H 1N5XA 4WFBJ 4C80A 2B7NA 1QPNA 1JROB 1YTKA 3H5QA 4LHMA 1YITH 4ZOHA 1UOUA 2JBMA 1FIQC 3G4SH 4KWVA 3VMMA 1WKIA 4X46A 3NVVC 3OW2H 1NJIJ 1YTEA 4IOAJ 2B7QA 3C2EA 1QPRA 3NS1C 5MLCO 2B7PA 4C7YA 4UY8M 1DGJA 4WF9J 3CC4H 2OTLH 3C2OA 5H1SO 1WYGA 5GADN 1JRPB 1RM6A 3I56H 5JVHJ 4USAA 1YIJH 5JVGJ 3BIIE 1Q86J 4WFNJ 4YYYA 5HL7J 4EADA 1VQOH 5HUPA 1NVIE 4US9A 5DM7J 4EAFA 2WP4A 1QVGH 3AN1A 1VQKH 5GAEN 1VQ8H 5AYXA 3G6EH 2DSJA 3I55H 2QEXH 3C2RA 4I9AA 3ETRC 2QA4H 3CF5J
chains in the Genus database with same CATH topology
1KC8J 1VQ9H 1W2BH 1KD1J 1QVFH 1YJ9H 3CCRH 3PIPJ 1M90J 5GAHN 3CPWH 3CD6H 3PIOJ 3CXCH 3CC7H 5AN9F 1Y69K 1VQNH 1YI2H 1Q7YJ 1KQSH 4IO9J 2ZJRJ 1VQ5H 3CCJH 1VQ4H 1K8AJ 1K9MJ 1M1KJ 3CCMH 1Q81J 3J7ZM 1VQPH 1VQMH 1YJWH 3CCVH 1S72H 1Q82J 1YJNH 5DM6J 2PA2A 1K73J 5GAGN 1VQLH 2ZJPJ 3CMAH 4WCEJ 3CMEH 3CC2H 3CCEH 3CCSH 4U67J 3G71H 3CCQH 4IOCJ 1N8RJ 3CCLH 1JJ2H 2OTJH 3CCUH 4WFAJ 1VQ7H 2ZJQJ 1YHQH 3DLLJ 1VQ6H 4WFBJ 1YITH 3G4SH 1WKIA 3OW2H 1NJIJ 4IOAJ 5MLCO 4UY8M 3CC4H 4WF9J 2OTLH 5H1SO 5GADN 3I56H 5JVHJ 1YIJH 5JVGJ 1Q86J 4WFNJ 5HL7J 1VQOH 5DM7J 1QVGH 1VQKH 5GAEN 1VQ8H 3G6EH 3I55H 2QEXH 2QA4H 3CF5J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KC8 J;  1VQ9 H;  1W2B H;  1KD1 J;  1QVF H;  1YJ9 H;  3CCR H;  3PIP J;  1M90 J;  5GAH N;  3CPW H;  3CD6 H;  3PIO J;  3CXC H;  3CC7 H;  5AN9 F;  1Y69 K;  1VQN H;  1YI2 H;  1Q7Y J;  1KQS H;  4IO9 J;  2ZJR J;  1VQ5 H;  3CCJ H;  1VQ4 H;  1K8A J;  1K9M J;  1M1K J;  3CCM H;  1Q81 J;  3J7Z M;  1VQP H;  1VQM H;  1YJW H;  3CCV H;  1S72 H;  1Q82 J;  1YJN H;  5DM6 J;  2PA2 A;  1K73 J;  5GAG N;  1VQL H;  2ZJP J;  3CMA H;  4WCE J;  3CME H;  3CC2 H;  3CCE H;  3CCS H;  4U67 J;  3G71 H;  3CCQ H;  4IOC J;  1N8R J;  3CCL H;  1JJ2 H;  2OTJ H;  3CCU H;  4WFA J;  1VQ7 H;  2ZJQ J;  1YHQ H;  3DLL J;  1VQ6 H;  4WFB J;  1YIT H;  3G4S H;  1WKI A;  3OW2 H;  1NJI J;  4IOA J;  5MLC O;  4UY8 M;  3CC4 H;  4WF9 J;  2OTL H;  5H1S O;  5GAD N;  3I56 H;  5JVH J;  1YIJ H;  5JVG J;  1Q86 J;  4WFN J;  5HL7 J;  1VQO H;  5DM7 J;  1QVG H;  1VQK H;  5GAE N;  1VQ8 H;  3G6E H;  3I55 H;  2QEX H;  2QA4 H;  3CF5 J; 
#chains in the Genus database with same CATH topology
 2E3T A;  1FFU B;  2TPT A;  3L4P A;  1KC8 J;  1VQ9 H;  1NVJ A;  5EP8 A;  1N61 B;  1ZXI B;  1W2B H;  1KD1 J;  4C7Z A;  1QVF H;  3FC4 A;  3L0G A;  1YJ9 H;  3C2V A;  3B9J C;  3CCR H;  1SB3 A;  3PIP J;  1N63 B;  5GAH N;  4GA6 A;  1M90 J;  3AMZ A;  3CPW H;  3PIO J;  3CD6 H;  3CXC H;  3CC7 H;  5AN9 F;  1Y69 K;  1VQN H;  1QPO A;  3GNN A;  1VLB A;  1YTD A;  1YI2 H;  1Q7Y J;  1KQS H;  1N5W B;  1N62 B;  4IO9 J;  2ZJR J;  1VQ5 H;  3CCJ H;  1VQ4 H;  1FMA E;  1K8A J;  1K9M J;  1M1K J;  3NRZ C;  3WNZ A;  5MPO C;  3CCM H;  2WK5 A;  2W55 B;  1Q81 J;  3J7Z M;  4XR5 A;  3NVZ C;  3TQV A;  1VQP H;  1SIJ A;  1VQM H;  2QIE A;  1YJW H;  2I14 A;  5HUL A;  3AM9 A;  2W54 B;  3SR6 C;  3C2F A;  1FO4 A;  3CCV H;  1S72 H;  1Q82 J;  1O4U A;  2J0F A;  5DM6 J;  3RPF A;  1YJN H;  1AZY A;  2PA2 A;  2Q5W E;  4GA5 A;  4YEK A;  3PAJ A;  1K73 J;  5GAG N;  1VQL H;  5EY3 A;  4AP8 A;  2ZJP J;  3CMA H;  1FFV B;  4WCE J;  3CME H;  4US8 A;  1N60 B;  3WO1 A;  3CC2 H;  1QAP A;  5AYY A;  3CCE H;  2OMD A;  2W3R B;  5AYZ A;  1V97 A;  3NVW C;  1QPQ A;  4U67 J;  3G71 H;  3CCS H;  2W3S B;  1FM0 E;  5HUO A;  4KWW A;  3CCQ H;  4IOC J;  3NVY C;  1N8R J;  3CCL H;  2WK6 A;  1OTP A;  1JJ2 H;  1X1O A;  3EUB 4;  2OTJ H;  3WO0 A;  3FAH A;  3CCU H;  1BRW A;  4WFA J;  1VQ7 H;  4GA4 A;  2ZJQ J;  2I1O A;  1VDV A;  1YHQ H;  3DLL J;  1VQ6 H;  1N5X A;  4WFB J;  4C80 A;  2B7N A;  1QPN A;  1JRO B;  1YTK A;  3H5Q A;  4LHM A;  1YIT H;  4ZOH A;  1UOU A;  2JBM A;  1FIQ C;  3G4S H;  4KWV A;  3VMM A;  1WKI A;  4X46 A;  3NVV C;  3OW2 H;  1NJI J;  1YTE A;  4IOA J;  2B7Q A;  3C2E A;  1QPR A;  3NS1 C;  5MLC O;  2B7P A;  4C7Y A;  4UY8 M;  1DGJ A;  4WF9 J;  3CC4 H;  2OTL H;  3C2O A;  5H1S O;  1WYG A;  5GAD N;  1JRP B;  1RM6 A;  3I56 H;  5JVH J;  4USA A;  1YIJ H;  5JVG J;  3BII E;  1Q86 J;  4WFN J;  4YYY A;  5HL7 J;  4EAD A;  1VQO H;  5HUP A;  1NVI E;  4US9 A;  5DM7 J;  4EAF A;  2WP4 A;  1QVG H;  3AN1 A;  1VQK H;  5GAE N;  1VQ8 H;  5AYX A;  3G6E H;  2DSJ A;  3I55 H;  2QEX H;  3C2R A;  4I9A A;  3ETR C;  2QA4 H;  3CF5 J; 
#chains in the Genus database with same CATH homology
 1KC8 J;  1VQ9 H;  1W2B H;  1KD1 J;  1QVF H;  1YJ9 H;  3CCR H;  3PIP J;  1M90 J;  5GAH N;  3CPW H;  3CD6 H;  3PIO J;  3CXC H;  3CC7 H;  5AN9 F;  1Y69 K;  1VQN H;  1YI2 H;  1Q7Y J;  1KQS H;  4IO9 J;  2ZJR J;  1VQ5 H;  3CCJ H;  1VQ4 H;  1K8A J;  1K9M J;  1M1K J;  3CCM H;  1Q81 J;  3J7Z M;  1VQP H;  1VQM H;  1YJW H;  3CCV H;  1S72 H;  1Q82 J;  1YJN H;  5DM6 J;  2PA2 A;  1K73 J;  5GAG N;  1VQL H;  2ZJP J;  3CMA H;  4WCE J;  3CME H;  3CC2 H;  3CCE H;  3CCS H;  4U67 J;  3G71 H;  3CCQ H;  4IOC J;  1N8R J;  3CCL H;  1JJ2 H;  2OTJ H;  3CCU H;  4WFA J;  1VQ7 H;  2ZJQ J;  1YHQ H;  3DLL J;  1VQ6 H;  4WFB J;  1YIT H;  3G4S H;  1WKI A;  3OW2 H;  1NJI J;  4IOA J;  5MLC O;  4UY8 M;  3CC4 H;  4WF9 J;  2OTL H;  5H1S O;  5GAD N;  3I56 H;  5JVH J;  1YIJ H;  5JVG J;  1Q86 J;  4WFN J;  5HL7 J;  1VQO H;  5DM7 J;  1QVG H;  1VQK H;  5GAE N;  1VQ8 H;  3G6E H;  3I55 H;  2QEX H;  2QA4 H;  3CF5 J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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