3CCLH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 38
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3cclH00
2QEXH 1K9MJ 2ZJQJ 1Q81J 3PIOJ 3CCSH 1S72H 4WCEJ 4U67J 1Q86J 3CC7H 5GADN 1Y69K 1KD1J 3CC2H 5JVHJ 3CCQH 3CCLH 3G4SH 3J7ZM 3CF5J 3CPWH 1YI2H 4WF9J 1Q7YJ 3CMEH 3I55H 1M90J 3CCUH 5DM7J 1VQ6H 4IO9J 1Q82J 5GAGN 3CCJH 5JVGJ 4WFAJ 1VQ8H 3CC4H 5GAHN 1WKIA 5GAEN 1VQ5H 5MLCO 1VQKH 1M1KJ 1N8RJ 2ZJRJ 4WFNJ 1VQOH 3G71H 2ZJPJ 2OTJH 3CCEH 3OW2H 1YJ9H 1K73J 3DLLJ 1K8AJ 3PIPJ 1VQNH 5H1SO 1YJWH 1VQMH 3CXCH 5AN9F 1JJ2H 1W2BH 3CCMH 1KQSH 1NJIJ 2OTLH 1VQLH 3CCRH 3G6EH 1YITH 1KC8J 4IOCJ 5DM6J 3CMAH 2QA4H 1VQ7H 1YIJH 4IOAJ 4UY8M 1YJNH 1YHQH 5HL7J 1VQ4H 3I56H 3CCVH 3CD6H 1QVFH 2PA2A 4WFBJ 1QVGH 1VQ9H 1VQPH
chains in the Genus database with same CATH superfamily
4US9A 4KWWA 2B7NA 2QEXH 1K9MJ 1V97A 5MPOC 4GA6A 2ZJQJ 3EUB4 1Q81J 3BIIE 4YYYA 3PIOJ 3CCSH 1QPOA 1S72H 4WCEJ 1RM6A 4U67J 1ZXIB 1FM0E 1Q86J 3CC7H 5GADN 1Y69K 1KD1J 3CC2H 5JVHJ 1WYGA 2JBMA 2OMDA 1X1OA 3CCQH 2WK5A 1FO4A 3CCLH 3G4SH 3J7ZM 3CF5J 3CPWH 1YI2H 4WF9J 3L4PA 4KWVA 1BRWA 3C2VA 1Q7YJ 3CMEH 1YTEA 1N60B 3ETRC 3C2EA 1O4UA 3I55H 3WNZA 1QPRA 3CCUH 1M90J 5AYXA 2B7QA 5DM7J 4YEKA 1VQ6H 4I9AA 1FFUB 1NVIE 4IO9J 1Q82J 1YTDA 5GAGN 3CCJH 1NVJA 5JVGJ 2E3TA 4WFAJ 1VQ8H 4GA4A 3CC4H 1N61B 4XR5A 5GAHN 1WKIA 5AYZA 5HUPA 5GAEN 3AN1A 1FFVB 1VQ5H 5MLCO 5HULA 2W3SB 1M1KJ 1VQKH 2WK6A 2W55B 3C2RA 2W3RB 3PAJA 1N8RJ 2ZJRJ 4WFNJ 3NVZC 1QAPA 2J0FA 1FIQC 1VQOH 1N62B 3G71H 1OTPA 2ZJPJ 5EP8A 2OTJH 1SIJA 3WO1A 1VLBA 3CCEH 3OW2H 4US8A 5EY3A 1YJ9H 1SB3A 4X46A 1K73J 3DLLJ 4C7ZA 1N63B 1K8AJ 2QIEA 3PIPJ 1VDVA 1VQNH 5H1SO 3B9JC 3C2OA 1YJWH 1VQMH 3L0GA 3CXCH 5AN9F 1QPQA 4ZOHA 3GNNA 1JJ2H 1W2BH 3TQVA 5AYYA 2I1OA 3CCMH 2W54B 2WP4A 4LHMA 1N5XA 1KQSH 1DGJA 3SR6C 5HUOA 1NJIJ 1N5WB 3AM9A 2TPTA 2OTLH 1VQLH 1QPNA 3CCRH 4C80A 3AMZA 4USAA 3WO0A 4EAFA 3G6EH 1YITH 1KC8J 4IOCJ 5DM6J 3CMAH 3FAHA 4EADA 3H5QA 2QA4H 1VQ7H 4GA5A 1YIJH 4IOAJ 2Q5WE 3NRZC 2I14A 4UY8M 3NVYC 1YTKA 3NVWC 3C2FA 3NS1C 1YJNH 3FC4A 1YHQH 5HL7J 4AP8A 3NVVC 1VQ4H 3I56H 1UOUA 3CCVH 3VMMA 3CD6H 1QVFH 1AZYA 2B7PA 2PA2A 4WFBJ 2DSJA 1QVGH 1VQ9H 4C7YA 1VQPH 1FMAE 1JRPB 1JROB 3RPFA
chains in the Genus database with same CATH topology
2QEXH 1K9MJ 2ZJQJ 1Q81J 3PIOJ 3CCSH 1S72H 4WCEJ 4U67J 1Q86J 3CC7H 5GADN 1Y69K 1KD1J 3CC2H 5JVHJ 3CCQH 3CCLH 3G4SH 3J7ZM 3CF5J 3CPWH 1YI2H 4WF9J 1Q7YJ 3CMEH 3I55H 1M90J 3CCUH 5DM7J 1VQ6H 4IO9J 1Q82J 5GAGN 3CCJH 5JVGJ 4WFAJ 1VQ8H 3CC4H 5GAHN 1WKIA 5GAEN 1VQ5H 5MLCO 1VQKH 1M1KJ 1N8RJ 2ZJRJ 4WFNJ 1VQOH 3G71H 2ZJPJ 2OTJH 3CCEH 3OW2H 1YJ9H 1K73J 3DLLJ 1K8AJ 3PIPJ 1VQNH 5H1SO 1YJWH 1VQMH 3CXCH 5AN9F 1JJ2H 1W2BH 3CCMH 1KQSH 1NJIJ 2OTLH 1VQLH 3CCRH 3G6EH 1YITH 1KC8J 4IOCJ 5DM6J 3CMAH 2QA4H 1VQ7H 1YIJH 4IOAJ 4UY8M 1YJNH 1YHQH 5HL7J 1VQ4H 3I56H 3CCVH 3CD6H 1QVFH 2PA2A 4WFBJ 1QVGH 1VQ9H 1VQPH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QEX H;  1K9M J;  2ZJQ J;  1Q81 J;  3PIO J;  3CCS H;  1S72 H;  4WCE J;  4U67 J;  1Q86 J;  3CC7 H;  5GAD N;  1Y69 K;  1KD1 J;  3CC2 H;  5JVH J;  3CCQ H;  3CCL H;  3G4S H;  3J7Z M;  3CF5 J;  3CPW H;  1YI2 H;  4WF9 J;  1Q7Y J;  3CME H;  3I55 H;  1M90 J;  3CCU H;  5DM7 J;  1VQ6 H;  4IO9 J;  1Q82 J;  5GAG N;  3CCJ H;  5JVG J;  4WFA J;  1VQ8 H;  3CC4 H;  5GAH N;  1WKI A;  5GAE N;  1VQ5 H;  5MLC O;  1VQK H;  1M1K J;  1N8R J;  2ZJR J;  4WFN J;  1VQO H;  3G71 H;  2ZJP J;  2OTJ H;  3CCE H;  3OW2 H;  1YJ9 H;  1K73 J;  3DLL J;  1K8A J;  3PIP J;  1VQN H;  5H1S O;  1YJW H;  1VQM H;  3CXC H;  5AN9 F;  1JJ2 H;  1W2B H;  3CCM H;  1KQS H;  1NJI J;  2OTL H;  1VQL H;  3CCR H;  3G6E H;  1YIT H;  1KC8 J;  4IOC J;  5DM6 J;  3CMA H;  2QA4 H;  1VQ7 H;  1YIJ H;  4IOA J;  4UY8 M;  1YJN H;  1YHQ H;  5HL7 J;  1VQ4 H;  3I56 H;  3CCV H;  3CD6 H;  1QVF H;  2PA2 A;  4WFB J;  1QVG H;  1VQ9 H;  1VQP H; 
#chains in the Genus database with same CATH topology
 4US9 A;  4KWW A;  2B7N A;  2QEX H;  1K9M J;  1V97 A;  5MPO C;  4GA6 A;  2ZJQ J;  3EUB 4;  1Q81 J;  3BII E;  4YYY A;  3PIO J;  3CCS H;  1QPO A;  1S72 H;  4WCE J;  1RM6 A;  4U67 J;  1ZXI B;  1FM0 E;  1Q86 J;  3CC7 H;  5GAD N;  1Y69 K;  1KD1 J;  3CC2 H;  5JVH J;  1WYG A;  2JBM A;  2OMD A;  1X1O A;  3CCQ H;  2WK5 A;  1FO4 A;  3CCL H;  3G4S H;  3J7Z M;  3CF5 J;  3CPW H;  1YI2 H;  4WF9 J;  3L4P A;  4KWV A;  1BRW A;  3C2V A;  1Q7Y J;  3CME H;  1YTE A;  1N60 B;  3ETR C;  3C2E A;  1O4U A;  3I55 H;  3WNZ A;  1QPR A;  3CCU H;  1M90 J;  5AYX A;  2B7Q A;  5DM7 J;  4YEK A;  1VQ6 H;  4I9A A;  1FFU B;  1NVI E;  4IO9 J;  1Q82 J;  1YTD A;  5GAG N;  3CCJ H;  1NVJ A;  5JVG J;  2E3T A;  4WFA J;  1VQ8 H;  4GA4 A;  3CC4 H;  1N61 B;  4XR5 A;  5GAH N;  1WKI A;  5AYZ A;  5HUP A;  5GAE N;  3AN1 A;  1FFV B;  1VQ5 H;  5MLC O;  5HUL A;  2W3S B;  1M1K J;  1VQK H;  2WK6 A;  2W55 B;  3C2R A;  2W3R B;  3PAJ A;  1N8R J;  2ZJR J;  4WFN J;  3NVZ C;  1QAP A;  2J0F A;  1FIQ C;  1VQO H;  1N62 B;  3G71 H;  1OTP A;  2ZJP J;  5EP8 A;  2OTJ H;  1SIJ A;  3WO1 A;  1VLB A;  3CCE H;  3OW2 H;  4US8 A;  5EY3 A;  1YJ9 H;  1SB3 A;  4X46 A;  1K73 J;  3DLL J;  4C7Z A;  1N63 B;  1K8A J;  2QIE A;  3PIP J;  1VDV A;  1VQN H;  5H1S O;  3B9J C;  3C2O A;  1YJW H;  1VQM H;  3L0G A;  3CXC H;  5AN9 F;  1QPQ A;  4ZOH A;  3GNN A;  1JJ2 H;  1W2B H;  3TQV A;  5AYY A;  2I1O A;  3CCM H;  2W54 B;  2WP4 A;  4LHM A;  1N5X A;  1KQS H;  1DGJ A;  3SR6 C;  5HUO A;  1NJI J;  1N5W B;  3AM9 A;  2TPT A;  2OTL H;  1VQL H;  1QPN A;  3CCR H;  4C80 A;  3AMZ A;  4USA A;  3WO0 A;  4EAF A;  3G6E H;  1YIT H;  1KC8 J;  4IOC J;  5DM6 J;  3CMA H;  3FAH A;  4EAD A;  3H5Q A;  2QA4 H;  1VQ7 H;  4GA5 A;  1YIJ H;  4IOA J;  2Q5W E;  3NRZ C;  2I14 A;  4UY8 M;  3NVY C;  1YTK A;  3NVW C;  3C2F A;  3NS1 C;  1YJN H;  3FC4 A;  1YHQ H;  5HL7 J;  4AP8 A;  3NVV C;  1VQ4 H;  3I56 H;  1UOU A;  3CCV H;  3VMM A;  3CD6 H;  1QVF H;  1AZY A;  2B7P A;  2PA2 A;  4WFB J;  2DSJ A;  1QVG H;  1VQ9 H;  4C7Y A;  1VQP H;  1FMA E;  1JRP B;  1JRO B;  3RPF A; 
#chains in the Genus database with same CATH homology
 2QEX H;  1K9M J;  2ZJQ J;  1Q81 J;  3PIO J;  3CCS H;  1S72 H;  4WCE J;  4U67 J;  1Q86 J;  3CC7 H;  5GAD N;  1Y69 K;  1KD1 J;  3CC2 H;  5JVH J;  3CCQ H;  3CCL H;  3G4S H;  3J7Z M;  3CF5 J;  3CPW H;  1YI2 H;  4WF9 J;  1Q7Y J;  3CME H;  3I55 H;  1M90 J;  3CCU H;  5DM7 J;  1VQ6 H;  4IO9 J;  1Q82 J;  5GAG N;  3CCJ H;  5JVG J;  4WFA J;  1VQ8 H;  3CC4 H;  5GAH N;  1WKI A;  5GAE N;  1VQ5 H;  5MLC O;  1VQK H;  1M1K J;  1N8R J;  2ZJR J;  4WFN J;  1VQO H;  3G71 H;  2ZJP J;  2OTJ H;  3CCE H;  3OW2 H;  1YJ9 H;  1K73 J;  3DLL J;  1K8A J;  3PIP J;  1VQN H;  5H1S O;  1YJW H;  1VQM H;  3CXC H;  5AN9 F;  1JJ2 H;  1W2B H;  3CCM H;  1KQS H;  1NJI J;  2OTL H;  1VQL H;  3CCR H;  3G6E H;  1YIT H;  1KC8 J;  4IOC J;  5DM6 J;  3CMA H;  2QA4 H;  1VQ7 H;  1YIJ H;  4IOA J;  4UY8 M;  1YJN H;  1YHQ H;  5HL7 J;  1VQ4 H;  3I56 H;  3CCV H;  3CD6 H;  1QVF H;  2PA2 A;  4WFB J;  1QVG H;  1VQ9 H;  1VQP H; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...