3CCSH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3ccsH00
5GAEN 4U67J 1KQSH 3I56H 4IOAJ 3CCVH 5H1SO 5DM7J 1VQ9H 1YJNH 3G71H 1Q7YJ 2ZJQJ 1VQNH 4IOCJ 1YI2H 1Y69K 1N8RJ 5MLCO 3CCLH 1VQMH 2QA4H 3CMAH 3J7ZM 4WFBJ 3CCEH 1VQKH 3CCMH 1VQPH 1M90J 1VQ8H 1Q82J 1YITH 2OTLH 4WFNJ 4WF9J 3CF5J 1QVGH 2QEXH 3CCQH 5DM6J 1YIJH 3CPWH 1K8AJ 1VQ7H 2ZJPJ 5JVGJ 1JJ2H 4WFAJ 5JVHJ 5GAGN 1VQLH 5AN9F 1M1KJ 3CCUH 3PIOJ 3CCRH 3CC7H 1KC8J 5HL7J 1VQ4H 3CCSH 2ZJRJ 1KD1J 2PA2A 3OW2H 5GAHN 1NJIJ 1WKIA 4WCEJ 3PIPJ 1VQ5H 4UY8M 3I55H 3CC2H 1VQ6H 1Q86J 1YHQH 5GADN 2OTJH 1S72H 1K73J 1Q81J 1K9MJ 1YJWH 3G6EH 3DLLJ 1W2BH 1YJ9H 3CCJH 3CD6H 3CC4H 1QVFH 4IO9J 3CXCH 3CMEH 1VQOH 3G4SH
chains in the Genus database with same CATH superfamily
5GAEN 4U67J 1N60B 3NVWC 1SB3A 1KQSH 1UOUA 2W3SB 3I56H 3CCVH 4IOAJ 5H1SO 5DM7J 1VQ9H 1YJNH 3G71H 1Q7YJ 3WNZA 5HULA 2J0FA 4YEKA 3C2EA 1QPNA 2ZJQJ 4IOCJ 1VQNH 1YI2H 1Y69K 1N8RJ 3H5QA 5MLCO 3CCLH 1VQMH 1QPQA 1QPRA 2QA4H 2B7PA 5HUOA 3VMMA 4US8A 3CMAH 1FFUB 3TQVA 3J7ZM 1DGJA 2WK5A 3FC4A 2WP4A 3L4PA 5HUPA 3WO0A 4YYYA 5MPOC 4WFBJ 3CCEH 1N63B 4EAFA 3WO1A 3CCMH 1VQPH 1M90J 1VQ8H 1VQKH 1Q82J 1N62B 4KWVA 1VLBA 1YITH 2Q5WE 2B7NA 2OTLH 1QPOA 4X46A 4WFNJ 4WF9J 1O4UA 4KWWA 2W54B 4USAA 3RPFA 3C2FA 3C2VA 2I1OA 3CF5J 1QVGH 2QEXH 3CCQH 2QIEA 1N61B 5DM6J 1YIJH 3CPWH 3NVVC 1JROB 1YTKA 3NRZC 1AZYA 4GA5A 1K8AJ 1VQ7H 5AYXA 2ZJPJ 1OTPA 5JVGJ 1JJ2H 1BRWA 4I9AA 4WFAJ 1WYGA 3C2RA 4GA6A 5JVHJ 3BIIE 3EUB4 3NS1C 3PAJA 5GAGN 1QAPA 5AN9F 1M1KJ 1VQLH 3CCUH 3FAHA 1FO4A 3PIOJ 2B7QA 4AP8A 3CCRH 3CC7H 1KC8J 2OMDA 5HL7J 1VQ4H 1YTDA 3CCSH 2W55B 3AMZA 1N5WB 3SR6C 1RM6A 2ZJRJ 1FFVB 3NVZC 1KD1J 1NVJA 2PA2A 1FM0E 2WK6A 3OW2H 3L0GA 5GAHN 3B9JC 4EADA 1NJIJ 1WKIA 5AYZA 3ETRC 4WCEJ 4ZOHA 3PIPJ 1VQ5H 1JRPB 4C7YA 4UY8M 1FMAE 1X1OA 3I55H 3CC2H 1VQ6H 2JBMA 1Q86J 1FIQC 1YHQH 2DSJA 5GADN 3C2OA 3AN1A 1S72H 2OTJH 3AM9A 1NVIE 1K73J 4XR5A 1YTEA 1Q81J 4LHMA 2I14A 1K9MJ 1N5XA 3GNNA 1YJWH 3G6EH 3DLLJ 1W2BH 1YJ9H 3CCJH 4US9A 3CD6H 2TPTA 3CC4H 1QVFH 4IO9J 2W3RB 5AYYA 5EP8A 4C7ZA 3NVYC 3CXCH 1ZXIB 1SIJA 1V97A 4C80A 1VDVA 2E3TA 4GA4A 5EY3A 1VQOH 3CMEH 3G4SH
chains in the Genus database with same CATH topology
5GAEN 4U67J 1KQSH 3I56H 4IOAJ 3CCVH 5H1SO 5DM7J 1VQ9H 1YJNH 3G71H 1Q7YJ 2ZJQJ 1VQNH 4IOCJ 1YI2H 1Y69K 1N8RJ 5MLCO 3CCLH 1VQMH 2QA4H 3CMAH 3J7ZM 4WFBJ 3CCEH 1VQKH 3CCMH 1VQPH 1M90J 1VQ8H 1Q82J 1YITH 2OTLH 4WFNJ 4WF9J 3CF5J 1QVGH 2QEXH 3CCQH 5DM6J 1YIJH 3CPWH 1K8AJ 1VQ7H 2ZJPJ 5JVGJ 1JJ2H 4WFAJ 5JVHJ 5GAGN 1VQLH 5AN9F 1M1KJ 3CCUH 3PIOJ 3CCRH 3CC7H 1KC8J 5HL7J 1VQ4H 3CCSH 2ZJRJ 1KD1J 2PA2A 3OW2H 5GAHN 1NJIJ 1WKIA 4WCEJ 3PIPJ 1VQ5H 4UY8M 3I55H 3CC2H 1VQ6H 1Q86J 1YHQH 5GADN 2OTJH 1S72H 1K73J 1Q81J 1K9MJ 1YJWH 3G6EH 3DLLJ 1W2BH 1YJ9H 3CCJH 3CD6H 3CC4H 1QVFH 4IO9J 3CXCH 3CMEH 1VQOH 3G4SH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAE N;  4U67 J;  1KQS H;  3I56 H;  4IOA J;  3CCV H;  5H1S O;  5DM7 J;  1VQ9 H;  1YJN H;  3G71 H;  1Q7Y J;  2ZJQ J;  1VQN H;  4IOC J;  1YI2 H;  1Y69 K;  1N8R J;  5MLC O;  3CCL H;  1VQM H;  2QA4 H;  3CMA H;  3J7Z M;  4WFB J;  3CCE H;  1VQK H;  3CCM H;  1VQP H;  1M90 J;  1VQ8 H;  1Q82 J;  1YIT H;  2OTL H;  4WFN J;  4WF9 J;  3CF5 J;  1QVG H;  2QEX H;  3CCQ H;  5DM6 J;  1YIJ H;  3CPW H;  1K8A J;  1VQ7 H;  2ZJP J;  5JVG J;  1JJ2 H;  4WFA J;  5JVH J;  5GAG N;  1VQL H;  5AN9 F;  1M1K J;  3CCU H;  3PIO J;  3CCR H;  3CC7 H;  1KC8 J;  5HL7 J;  1VQ4 H;  3CCS H;  2ZJR J;  1KD1 J;  2PA2 A;  3OW2 H;  5GAH N;  1NJI J;  1WKI A;  4WCE J;  3PIP J;  1VQ5 H;  4UY8 M;  3I55 H;  3CC2 H;  1VQ6 H;  1Q86 J;  1YHQ H;  5GAD N;  2OTJ H;  1S72 H;  1K73 J;  1Q81 J;  1K9M J;  1YJW H;  3G6E H;  3DLL J;  1W2B H;  1YJ9 H;  3CCJ H;  3CD6 H;  3CC4 H;  1QVF H;  4IO9 J;  3CXC H;  3CME H;  1VQO H;  3G4S H; 
#chains in the Genus database with same CATH topology
 5GAE N;  4U67 J;  1N60 B;  3NVW C;  1SB3 A;  1KQS H;  1UOU A;  2W3S B;  3I56 H;  3CCV H;  4IOA J;  5H1S O;  5DM7 J;  1VQ9 H;  1YJN H;  3G71 H;  1Q7Y J;  3WNZ A;  5HUL A;  2J0F A;  4YEK A;  3C2E A;  1QPN A;  2ZJQ J;  4IOC J;  1VQN H;  1YI2 H;  1Y69 K;  1N8R J;  3H5Q A;  5MLC O;  3CCL H;  1VQM H;  1QPQ A;  1QPR A;  2QA4 H;  2B7P A;  5HUO A;  3VMM A;  4US8 A;  3CMA H;  1FFU B;  3TQV A;  3J7Z M;  1DGJ A;  2WK5 A;  3FC4 A;  2WP4 A;  3L4P A;  5HUP A;  3WO0 A;  4YYY A;  5MPO C;  4WFB J;  3CCE H;  1N63 B;  4EAF A;  3WO1 A;  3CCM H;  1VQP H;  1M90 J;  1VQ8 H;  1VQK H;  1Q82 J;  1N62 B;  4KWV A;  1VLB A;  1YIT H;  2Q5W E;  2B7N A;  2OTL H;  1QPO A;  4X46 A;  4WFN J;  4WF9 J;  1O4U A;  4KWW A;  2W54 B;  4USA A;  3RPF A;  3C2F A;  3C2V A;  2I1O A;  3CF5 J;  1QVG H;  2QEX H;  3CCQ H;  2QIE A;  1N61 B;  5DM6 J;  1YIJ H;  3CPW H;  3NVV C;  1JRO B;  1YTK A;  3NRZ C;  1AZY A;  4GA5 A;  1K8A J;  1VQ7 H;  5AYX A;  2ZJP J;  1OTP A;  5JVG J;  1JJ2 H;  1BRW A;  4I9A A;  4WFA J;  1WYG A;  3C2R A;  4GA6 A;  5JVH J;  3BII E;  3EUB 4;  3NS1 C;  3PAJ A;  5GAG N;  1QAP A;  5AN9 F;  1M1K J;  1VQL H;  3CCU H;  3FAH A;  1FO4 A;  3PIO J;  2B7Q A;  4AP8 A;  3CCR H;  3CC7 H;  1KC8 J;  2OMD A;  5HL7 J;  1VQ4 H;  1YTD A;  3CCS H;  2W55 B;  3AMZ A;  1N5W B;  3SR6 C;  1RM6 A;  2ZJR J;  1FFV B;  3NVZ C;  1KD1 J;  1NVJ A;  2PA2 A;  1FM0 E;  2WK6 A;  3OW2 H;  3L0G A;  5GAH N;  3B9J C;  4EAD A;  1NJI J;  1WKI A;  5AYZ A;  3ETR C;  4WCE J;  4ZOH A;  3PIP J;  1VQ5 H;  1JRP B;  4C7Y A;  4UY8 M;  1FMA E;  1X1O A;  3I55 H;  3CC2 H;  1VQ6 H;  2JBM A;  1Q86 J;  1FIQ C;  1YHQ H;  2DSJ A;  5GAD N;  3C2O A;  3AN1 A;  1S72 H;  2OTJ H;  3AM9 A;  1NVI E;  1K73 J;  4XR5 A;  1YTE A;  1Q81 J;  4LHM A;  2I14 A;  1K9M J;  1N5X A;  3GNN A;  1YJW H;  3G6E H;  3DLL J;  1W2B H;  1YJ9 H;  3CCJ H;  4US9 A;  3CD6 H;  2TPT A;  3CC4 H;  1QVF H;  4IO9 J;  2W3R B;  5AYY A;  5EP8 A;  4C7Z A;  3NVY C;  3CXC H;  1ZXI B;  1SIJ A;  1V97 A;  4C80 A;  1VDV A;  2E3T A;  4GA4 A;  5EY3 A;  1VQO H;  3CME H;  3G4S H; 
#chains in the Genus database with same CATH homology
 5GAE N;  4U67 J;  1KQS H;  3I56 H;  4IOA J;  3CCV H;  5H1S O;  5DM7 J;  1VQ9 H;  1YJN H;  3G71 H;  1Q7Y J;  2ZJQ J;  1VQN H;  4IOC J;  1YI2 H;  1Y69 K;  1N8R J;  5MLC O;  3CCL H;  1VQM H;  2QA4 H;  3CMA H;  3J7Z M;  4WFB J;  3CCE H;  1VQK H;  3CCM H;  1VQP H;  1M90 J;  1VQ8 H;  1Q82 J;  1YIT H;  2OTL H;  4WFN J;  4WF9 J;  3CF5 J;  1QVG H;  2QEX H;  3CCQ H;  5DM6 J;  1YIJ H;  3CPW H;  1K8A J;  1VQ7 H;  2ZJP J;  5JVG J;  1JJ2 H;  4WFA J;  5JVH J;  5GAG N;  1VQL H;  5AN9 F;  1M1K J;  3CCU H;  3PIO J;  3CCR H;  3CC7 H;  1KC8 J;  5HL7 J;  1VQ4 H;  3CCS H;  2ZJR J;  1KD1 J;  2PA2 A;  3OW2 H;  5GAH N;  1NJI J;  1WKI A;  4WCE J;  3PIP J;  1VQ5 H;  4UY8 M;  3I55 H;  3CC2 H;  1VQ6 H;  1Q86 J;  1YHQ H;  5GAD N;  2OTJ H;  1S72 H;  1K73 J;  1Q81 J;  1K9M J;  1YJW H;  3G6E H;  3DLL J;  1W2B H;  1YJ9 H;  3CCJ H;  3CD6 H;  3CC4 H;  1QVF H;  4IO9 J;  3CXC H;  3CME H;  1VQO H;  3G4S H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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