3CCUH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482c
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 39
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3ccuH00
5GAHN 3CCSH 3G6EH 3CD6H 3G71H 1KQSH 1VQ5H 1VQPH 3CMEH 2QEXH 3PIPJ 1VQ9H 4IOAJ 1YIJH 5H1SO 5GAGN 4WFAJ 2ZJPJ 5GADN 3G4SH 1K73J 1Q82J 1Q81J 1VQNH 4UY8M 1Q7YJ 1M90J 1JJ2H 3J7ZM 1YHQH 3DLLJ 3CC2H 2QA4H 3PIOJ 4WFBJ 1VQLH 5HL7J 1M1KJ 1WKIA 1VQMH 3CMAH 1VQ4H 3CCMH 5AN9F 4U67J 3CC7H 3CCQH 5JVHJ 1Q86J 3I56H 5DM7J 3CF5J 1VQKH 3CCUH 1YITH 1QVFH 1YJWH 1VQ7H 4WF9J 1Y69K 5GAEN 4IO9J 1K8AJ 1K9MJ 3CCLH 4WFNJ 3CCRH 1N8RJ 5MLCO 2OTLH 2ZJQJ 2OTJH 3CXCH 1KC8J 2ZJRJ 1KD1J 3CCJH 2PA2A 1VQ6H 1QVGH 3CC4H 3CPWH 3CCVH 1NJIJ 3CCEH 1VQOH 5JVGJ 4IOCJ 1YJNH 1S72H 5DM6J 3I55H 3OW2H 1YJ9H 1W2BH 1VQ8H 4WCEJ 1YI2H
chains in the Genus database with same CATH superfamily
1SIJA 5GAHN 3CCSH 4KWWA 3G6EH 3GNNA 3CD6H 5AYYA 2B7QA 3RPFA 2Q5WE 1FO4A 1N63B 1VDVA 3G71H 3WO0A 1KQSH 4US9A 4WCEJ 1VQ5H 3BIIE 2W3RB 1N60B 1VQPH 1DGJA 2W55B 2I1OA 5EP8A 1N61B 2QEXH 3CMEH 3WO1A 1VLBA 3PIPJ 1VQ9H 4IOAJ 3H5QA 4X46A 1YIJH 2B7PA 2WP4A 5H1SO 1X1OA 3NVWC 4EADA 4KWVA 2B7NA 3SR6C 5GAGN 4ZOHA 4WFAJ 2ZJPJ 5GADN 4I9AA 3G4SH 1QAPA 2I14A 1NVJA 1V97A 1YTEA 1K73J 3AN1A 1FMAE 4YYYA 3NRZC 1Q82J 4C80A 1Q81J 1VQNH 3L0GA 4UY8M 3C2EA 1YTDA 1FFVB 2OMDA 2QIEA 1Q7YJ 1M90J 1JJ2H 3C2OA 5HULA 3J7ZM 1YHQH 1OTPA 3DLLJ 4C7ZA 3CC2H 2QA4H 3PIOJ 4WFBJ 1VQLH 3C2RA 1N5XA 5HL7J 1M1KJ 1WKIA 2W54B 2JBMA 1O4UA 3NVVC 1VQMH 3CMAH 1N5WB 5EY3A 4XR5A 1VQ4H 3C2VA 3CCMH 5AN9F 3NVZC 4EAFA 4U67J 3CC7H 1QPQA 3CCQH 1N62B 5JVHJ 1Q86J 1QPRA 3I56H 5DM7J 4GA5A 3CF5J 4AP8A 3EUB4 1VQKH 3CCUH 1YITH 1QVFH 5AYXA 4C7YA 4GA6A 1YJWH 3ETRC 1VQ7H 1AZYA 3C2FA 4WF9J 1Y69K 5GAEN 4IO9J 1K8AJ 1BRWA 1FM0E 1K9MJ 3CCLH 1UOUA 1WYGA 1NVIE 4WFNJ 1JRPB 3WNZA 3FAHA 3CCRH 1N8RJ 3VMMA 5MLCO 2OTLH 2ZJQJ 2OTJH 5AYZA 1YTKA 2DSJA 3CXCH 1KC8J 2ZJRJ 1KD1J 3CCJH 1FIQC 3L4PA 2PA2A 3TQVA 1SB3A 1VQ6H 1QVGH 1RM6A 4LHMA 1FFUB 2E3TA 4YEKA 1QPOA 3CC4H 3CPWH 5HUOA 3PAJA 3CCVH 1ZXIB 3NS1C 1NJIJ 3FC4A 3CCEH 1VQOH 5JVGJ 4USAA 4IOCJ 2W3SB 4GA4A 2TPTA 3AMZA 3NVYC 1YJNH 1S72H 4US8A 3AM9A 5DM6J 3I55H 3B9JC 3OW2H 2J0FA 5MPOC 1YJ9H 1W2BH 2WK5A 1QPNA 2WK6A 5HUPA 1VQ8H 1JROB 1YI2H
chains in the Genus database with same CATH topology
5GAHN 3CCSH 3G6EH 3CD6H 3G71H 1KQSH 1VQ5H 1VQPH 3CMEH 2QEXH 3PIPJ 1VQ9H 4IOAJ 1YIJH 5H1SO 5GAGN 4WFAJ 2ZJPJ 5GADN 3G4SH 1K73J 1Q82J 1Q81J 1VQNH 4UY8M 1Q7YJ 1M90J 1JJ2H 3J7ZM 1YHQH 3DLLJ 3CC2H 2QA4H 3PIOJ 4WFBJ 1VQLH 5HL7J 1M1KJ 1WKIA 1VQMH 3CMAH 1VQ4H 3CCMH 5AN9F 4U67J 3CC7H 3CCQH 5JVHJ 1Q86J 3I56H 5DM7J 3CF5J 1VQKH 3CCUH 1YITH 1QVFH 1YJWH 1VQ7H 4WF9J 1Y69K 5GAEN 4IO9J 1K8AJ 1K9MJ 3CCLH 4WFNJ 3CCRH 1N8RJ 5MLCO 2OTLH 2ZJQJ 2OTJH 3CXCH 1KC8J 2ZJRJ 1KD1J 3CCJH 2PA2A 1VQ6H 1QVGH 3CC4H 3CPWH 3CCVH 1NJIJ 3CCEH 1VQOH 5JVGJ 4IOCJ 1YJNH 1S72H 5DM6J 3I55H 3OW2H 1YJ9H 1W2BH 1VQ8H 4WCEJ 1YI2H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAH N;  3CCS H;  3G6E H;  3CD6 H;  3G71 H;  1KQS H;  1VQ5 H;  1VQP H;  3CME H;  2QEX H;  3PIP J;  1VQ9 H;  4IOA J;  1YIJ H;  5H1S O;  5GAG N;  4WFA J;  2ZJP J;  5GAD N;  3G4S H;  1K73 J;  1Q82 J;  1Q81 J;  1VQN H;  4UY8 M;  1Q7Y J;  1M90 J;  1JJ2 H;  3J7Z M;  1YHQ H;  3DLL J;  3CC2 H;  2QA4 H;  3PIO J;  4WFB J;  1VQL H;  5HL7 J;  1M1K J;  1WKI A;  1VQM H;  3CMA H;  1VQ4 H;  3CCM H;  5AN9 F;  4U67 J;  3CC7 H;  3CCQ H;  5JVH J;  1Q86 J;  3I56 H;  5DM7 J;  3CF5 J;  1VQK H;  3CCU H;  1YIT H;  1QVF H;  1YJW H;  1VQ7 H;  4WF9 J;  1Y69 K;  5GAE N;  4IO9 J;  1K8A J;  1K9M J;  3CCL H;  4WFN J;  3CCR H;  1N8R J;  5MLC O;  2OTL H;  2ZJQ J;  2OTJ H;  3CXC H;  1KC8 J;  2ZJR J;  1KD1 J;  3CCJ H;  2PA2 A;  1VQ6 H;  1QVG H;  3CC4 H;  3CPW H;  3CCV H;  1NJI J;  3CCE H;  1VQO H;  5JVG J;  4IOC J;  1YJN H;  1S72 H;  5DM6 J;  3I55 H;  3OW2 H;  1YJ9 H;  1W2B H;  1VQ8 H;  4WCE J;  1YI2 H; 
#chains in the Genus database with same CATH topology
 1SIJ A;  5GAH N;  3CCS H;  4KWW A;  3G6E H;  3GNN A;  3CD6 H;  5AYY A;  2B7Q A;  3RPF A;  2Q5W E;  1FO4 A;  1N63 B;  1VDV A;  3G71 H;  3WO0 A;  1KQS H;  4US9 A;  4WCE J;  1VQ5 H;  3BII E;  2W3R B;  1N60 B;  1VQP H;  1DGJ A;  2W55 B;  2I1O A;  5EP8 A;  1N61 B;  2QEX H;  3CME H;  3WO1 A;  1VLB A;  3PIP J;  1VQ9 H;  4IOA J;  3H5Q A;  4X46 A;  1YIJ H;  2B7P A;  2WP4 A;  5H1S O;  1X1O A;  3NVW C;  4EAD A;  4KWV A;  2B7N A;  3SR6 C;  5GAG N;  4ZOH A;  4WFA J;  2ZJP J;  5GAD N;  4I9A A;  3G4S H;  1QAP A;  2I14 A;  1NVJ A;  1V97 A;  1YTE A;  1K73 J;  3AN1 A;  1FMA E;  4YYY A;  3NRZ C;  1Q82 J;  4C80 A;  1Q81 J;  1VQN H;  3L0G A;  4UY8 M;  3C2E A;  1YTD A;  1FFV B;  2OMD A;  2QIE A;  1Q7Y J;  1M90 J;  1JJ2 H;  3C2O A;  5HUL A;  3J7Z M;  1YHQ H;  1OTP A;  3DLL J;  4C7Z A;  3CC2 H;  2QA4 H;  3PIO J;  4WFB J;  1VQL H;  3C2R A;  1N5X A;  5HL7 J;  1M1K J;  1WKI A;  2W54 B;  2JBM A;  1O4U A;  3NVV C;  1VQM H;  3CMA H;  1N5W B;  5EY3 A;  4XR5 A;  1VQ4 H;  3C2V A;  3CCM H;  5AN9 F;  3NVZ C;  4EAF A;  4U67 J;  3CC7 H;  1QPQ A;  3CCQ H;  1N62 B;  5JVH J;  1Q86 J;  1QPR A;  3I56 H;  5DM7 J;  4GA5 A;  3CF5 J;  4AP8 A;  3EUB 4;  1VQK H;  3CCU H;  1YIT H;  1QVF H;  5AYX A;  4C7Y A;  4GA6 A;  1YJW H;  3ETR C;  1VQ7 H;  1AZY A;  3C2F A;  4WF9 J;  1Y69 K;  5GAE N;  4IO9 J;  1K8A J;  1BRW A;  1FM0 E;  1K9M J;  3CCL H;  1UOU A;  1WYG A;  1NVI E;  4WFN J;  1JRP B;  3WNZ A;  3FAH A;  3CCR H;  1N8R J;  3VMM A;  5MLC O;  2OTL H;  2ZJQ J;  2OTJ H;  5AYZ A;  1YTK A;  2DSJ A;  3CXC H;  1KC8 J;  2ZJR J;  1KD1 J;  3CCJ H;  1FIQ C;  3L4P A;  2PA2 A;  3TQV A;  1SB3 A;  1VQ6 H;  1QVG H;  1RM6 A;  4LHM A;  1FFU B;  2E3T A;  4YEK A;  1QPO A;  3CC4 H;  3CPW H;  5HUO A;  3PAJ A;  3CCV H;  1ZXI B;  3NS1 C;  1NJI J;  3FC4 A;  3CCE H;  1VQO H;  5JVG J;  4USA A;  4IOC J;  2W3S B;  4GA4 A;  2TPT A;  3AMZ A;  3NVY C;  1YJN H;  1S72 H;  4US8 A;  3AM9 A;  5DM6 J;  3I55 H;  3B9J C;  3OW2 H;  2J0F A;  5MPO C;  1YJ9 H;  1W2B H;  2WK5 A;  1QPN A;  2WK6 A;  5HUP A;  1VQ8 H;  1JRO B;  1YI2 H; 
#chains in the Genus database with same CATH homology
 5GAH N;  3CCS H;  3G6E H;  3CD6 H;  3G71 H;  1KQS H;  1VQ5 H;  1VQP H;  3CME H;  2QEX H;  3PIP J;  1VQ9 H;  4IOA J;  1YIJ H;  5H1S O;  5GAG N;  4WFA J;  2ZJP J;  5GAD N;  3G4S H;  1K73 J;  1Q82 J;  1Q81 J;  1VQN H;  4UY8 M;  1Q7Y J;  1M90 J;  1JJ2 H;  3J7Z M;  1YHQ H;  3DLL J;  3CC2 H;  2QA4 H;  3PIO J;  4WFB J;  1VQL H;  5HL7 J;  1M1K J;  1WKI A;  1VQM H;  3CMA H;  1VQ4 H;  3CCM H;  5AN9 F;  4U67 J;  3CC7 H;  3CCQ H;  5JVH J;  1Q86 J;  3I56 H;  5DM7 J;  3CF5 J;  1VQK H;  3CCU H;  1YIT H;  1QVF H;  1YJW H;  1VQ7 H;  4WF9 J;  1Y69 K;  5GAE N;  4IO9 J;  1K8A J;  1K9M J;  3CCL H;  4WFN J;  3CCR H;  1N8R J;  5MLC O;  2OTL H;  2ZJQ J;  2OTJ H;  3CXC H;  1KC8 J;  2ZJR J;  1KD1 J;  3CCJ H;  2PA2 A;  1VQ6 H;  1QVG H;  3CC4 H;  3CPW H;  3CCV H;  1NJI J;  3CCE H;  1VQO H;  5JVG J;  4IOC J;  1YJN H;  1S72 H;  5DM6 J;  3I55 H;  3OW2 H;  1YJ9 H;  1W2B H;  1VQ8 H;  4WCE J;  1YI2 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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