3CCVH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 42
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3ccvH00
1YIJH 1KQSH 4WF9J 1YJ9H 1VQ4H 1VQKH 3CCQH 1KD1J 1M1KJ 1QVGH 3DLLJ 1VQ5H 1VQNH 3CD6H 2ZJQJ 3G4SH 1W2BH 1VQLH 1K8AJ 4IO9J 1N8RJ 4UY8M 1K73J 1VQ7H 1VQOH 1YHQH 3CPWH 3G6EH 3I55H 1YJNH 3CCMH 4WFAJ 3CCUH 5MLCO 3CCRH 1YI2H 5DM6J 3PIPJ 2OTJH 5H1SO 1M90J 5GAHN 1K9MJ 5GAGN 3I56H 2OTLH 1KC8J 5JVGJ 1VQPH 2ZJPJ 1NJIJ 3CC7H 3CC4H 1Q86J 5GAEN 1Q82J 5HL7J 4U67J 1YJWH 3CCLH 2QA4H 3CCSH 1VQMH 5GADN 3CMAH 2QEXH 3CCEH 4IOCJ 4WFNJ 3CF5J 3OW2H 3J7ZM 3CCVH 3G71H 1Y69K 3CXCH 4WCEJ 1Q7YJ 5AN9F 1QVFH 1Q81J 5JVHJ 3CC2H 1VQ6H 5DM7J 2PA2A 1VQ8H 1VQ9H 1YITH 1WKIA 1S72H 3PIOJ 3CMEH 3CCJH 4WFBJ 1JJ2H 2ZJRJ 4IOAJ
chains in the Genus database with same CATH superfamily
4GA5A 1YTKA 2TPTA 1YTDA 4I9AA 1AZYA 2DSJA 4WF9J 1YIJH 1KQSH 3EUB4 5AYXA 1WYGA 2WP4A 1YJ9H 1VQ4H 1VQKH 3CCQH 1KD1J 5HUOA 4X46A 3SR6C 1JROB 1M1KJ 3NVVC 1ZXIB 1YTEA 4GA6A 3GNNA 1QVGH 1SIJA 3DLLJ 3NVZC 1VQ5H 1VQNH 3CD6H 2ZJQJ 2QIEA 3G4SH 1W2BH 1VQLH 1K8AJ 1N62B 1RM6A 1O4UA 4IO9J 1SB3A 3B9JC 1N8RJ 4UY8M 3NVWC 1K73J 3C2RA 2JBMA 5HULA 1VQ7H 4KWWA 1VQOH 1N60B 1DGJA 3C2OA 1YHQH 3CPWH 1NVJA 3NRZC 3G6EH 3ETRC 3I55H 3C2FA 4YEKA 1YJNH 3CCMH 4WFAJ 3CCUH 3NS1C 5MLCO 3TQVA 1BRWA 1FFVB 4GA4A 3CCRH 3FAHA 5HUPA 1YI2H 3L4PA 4C7ZA 5EP8A 5DM6J 3PIPJ 2OTJH 5AYYA 1FM0E 1QPOA 5H1SO 2J0FA 1M90J 5GAHN 1K9MJ 1QPRA 5GAGN 3C2VA 1QPQA 3I56H 1X1OA 3WO1A 2W3RB 2OTLH 1KC8J 4US9A 5JVGJ 4EADA 1FO4A 1VQPH 1OTPA 5EY3A 2ZJPJ 1NJIJ 5MPOC 3WO0A 3CC7H 3H5QA 3CC4H 1Q86J 4C80A 3AM9A 5GAEN 1Q82J 5HL7J 4AP8A 4U67J 1YJWH 2OMDA 2W54B 3RPFA 3L0GA 1UOUA 4C7YA 3CCLH 2WK6A 3CCSH 2I14A 2QA4H 2Q5WE 1VQMH 4EAFA 5GADN 3CMAH 3FC4A 1VLBA 3VMMA 2QEXH 3NVYC 2B7QA 3CCEH 2WK5A 4IOCJ 2W55B 4WFNJ 3AN1A 1N5WB 3CF5J 3OW2H 3J7ZM 3CCVH 1N63B 4ZOHA 3BIIE 3WNZA 3G71H 2E3TA 1FMAE 2W3SB 2I1OA 3CXCH 1JRPB 4WCEJ 1Y69K 1QPNA 1Q7YJ 1QAPA 5AN9F 1N61B 1NVIE 1QVFH 1Q81J 5JVHJ 3CC2H 3PAJA 1VQ6H 1V97A 5DM7J 3C2EA 2PA2A 5AYZA 1VQ8H 1VQ9H 1FIQC 3AMZA 1YITH 1WKIA 2B7PA 2B7NA 4XR5A 1N5XA 1S72H 4YYYA 1VDVA 3PIOJ 3CMEH 4US8A 4KWVA 3CCJH 4USAA 4WFBJ 1JJ2H 2ZJRJ 4LHMA 4IOAJ 1FFUB
chains in the Genus database with same CATH topology
1YIJH 1KQSH 4WF9J 1YJ9H 1VQ4H 1VQKH 3CCQH 1KD1J 1M1KJ 1QVGH 3DLLJ 1VQ5H 1VQNH 3CD6H 2ZJQJ 3G4SH 1W2BH 1VQLH 1K8AJ 4IO9J 1N8RJ 4UY8M 1K73J 1VQ7H 1VQOH 1YHQH 3CPWH 3G6EH 3I55H 1YJNH 3CCMH 4WFAJ 3CCUH 5MLCO 3CCRH 1YI2H 5DM6J 3PIPJ 2OTJH 5H1SO 1M90J 5GAHN 1K9MJ 5GAGN 3I56H 2OTLH 1KC8J 5JVGJ 1VQPH 2ZJPJ 1NJIJ 3CC7H 3CC4H 1Q86J 5GAEN 1Q82J 5HL7J 4U67J 1YJWH 3CCLH 2QA4H 3CCSH 1VQMH 5GADN 3CMAH 2QEXH 3CCEH 4IOCJ 4WFNJ 3CF5J 3OW2H 3J7ZM 3CCVH 3G71H 1Y69K 3CXCH 4WCEJ 1Q7YJ 5AN9F 1QVFH 1Q81J 5JVHJ 3CC2H 1VQ6H 5DM7J 2PA2A 1VQ8H 1VQ9H 1YITH 1WKIA 1S72H 3PIOJ 3CMEH 3CCJH 4WFBJ 1JJ2H 2ZJRJ 4IOAJ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YIJ H;  1KQS H;  4WF9 J;  1YJ9 H;  1VQ4 H;  1VQK H;  3CCQ H;  1KD1 J;  1M1K J;  1QVG H;  3DLL J;  1VQ5 H;  1VQN H;  3CD6 H;  2ZJQ J;  3G4S H;  1W2B H;  1VQL H;  1K8A J;  4IO9 J;  1N8R J;  4UY8 M;  1K73 J;  1VQ7 H;  1VQO H;  1YHQ H;  3CPW H;  3G6E H;  3I55 H;  1YJN H;  3CCM H;  4WFA J;  3CCU H;  5MLC O;  3CCR H;  1YI2 H;  5DM6 J;  3PIP J;  2OTJ H;  5H1S O;  1M90 J;  5GAH N;  1K9M J;  5GAG N;  3I56 H;  2OTL H;  1KC8 J;  5JVG J;  1VQP H;  2ZJP J;  1NJI J;  3CC7 H;  3CC4 H;  1Q86 J;  5GAE N;  1Q82 J;  5HL7 J;  4U67 J;  1YJW H;  3CCL H;  2QA4 H;  3CCS H;  1VQM H;  5GAD N;  3CMA H;  2QEX H;  3CCE H;  4IOC J;  4WFN J;  3CF5 J;  3OW2 H;  3J7Z M;  3CCV H;  3G71 H;  1Y69 K;  3CXC H;  4WCE J;  1Q7Y J;  5AN9 F;  1QVF H;  1Q81 J;  5JVH J;  3CC2 H;  1VQ6 H;  5DM7 J;  2PA2 A;  1VQ8 H;  1VQ9 H;  1YIT H;  1WKI A;  1S72 H;  3PIO J;  3CME H;  3CCJ H;  4WFB J;  1JJ2 H;  2ZJR J;  4IOA J; 
#chains in the Genus database with same CATH topology
 4GA5 A;  1YTK A;  2TPT A;  1YTD A;  4I9A A;  1AZY A;  2DSJ A;  4WF9 J;  1YIJ H;  1KQS H;  3EUB 4;  5AYX A;  1WYG A;  2WP4 A;  1YJ9 H;  1VQ4 H;  1VQK H;  3CCQ H;  1KD1 J;  5HUO A;  4X46 A;  3SR6 C;  1JRO B;  1M1K J;  3NVV C;  1ZXI B;  1YTE A;  4GA6 A;  3GNN A;  1QVG H;  1SIJ A;  3DLL J;  3NVZ C;  1VQ5 H;  1VQN H;  3CD6 H;  2ZJQ J;  2QIE A;  3G4S H;  1W2B H;  1VQL H;  1K8A J;  1N62 B;  1RM6 A;  1O4U A;  4IO9 J;  1SB3 A;  3B9J C;  1N8R J;  4UY8 M;  3NVW C;  1K73 J;  3C2R A;  2JBM A;  5HUL A;  1VQ7 H;  4KWW A;  1VQO H;  1N60 B;  1DGJ A;  3C2O A;  1YHQ H;  3CPW H;  1NVJ A;  3NRZ C;  3G6E H;  3ETR C;  3I55 H;  3C2F A;  4YEK A;  1YJN H;  3CCM H;  4WFA J;  3CCU H;  3NS1 C;  5MLC O;  3TQV A;  1BRW A;  1FFV B;  4GA4 A;  3CCR H;  3FAH A;  5HUP A;  1YI2 H;  3L4P A;  4C7Z A;  5EP8 A;  5DM6 J;  3PIP J;  2OTJ H;  5AYY A;  1FM0 E;  1QPO A;  5H1S O;  2J0F A;  1M90 J;  5GAH N;  1K9M J;  1QPR A;  5GAG N;  3C2V A;  1QPQ A;  3I56 H;  1X1O A;  3WO1 A;  2W3R B;  2OTL H;  1KC8 J;  4US9 A;  5JVG J;  4EAD A;  1FO4 A;  1VQP H;  1OTP A;  5EY3 A;  2ZJP J;  1NJI J;  5MPO C;  3WO0 A;  3CC7 H;  3H5Q A;  3CC4 H;  1Q86 J;  4C80 A;  3AM9 A;  5GAE N;  1Q82 J;  5HL7 J;  4AP8 A;  4U67 J;  1YJW H;  2OMD A;  2W54 B;  3RPF A;  3L0G A;  1UOU A;  4C7Y A;  3CCL H;  2WK6 A;  3CCS H;  2I14 A;  2QA4 H;  2Q5W E;  1VQM H;  4EAF A;  5GAD N;  3CMA H;  3FC4 A;  1VLB A;  3VMM A;  2QEX H;  3NVY C;  2B7Q A;  3CCE H;  2WK5 A;  4IOC J;  2W55 B;  4WFN J;  3AN1 A;  1N5W B;  3CF5 J;  3OW2 H;  3J7Z M;  3CCV H;  1N63 B;  4ZOH A;  3BII E;  3WNZ A;  3G71 H;  2E3T A;  1FMA E;  2W3S B;  2I1O A;  3CXC H;  1JRP B;  4WCE J;  1Y69 K;  1QPN A;  1Q7Y J;  1QAP A;  5AN9 F;  1N61 B;  1NVI E;  1QVF H;  1Q81 J;  5JVH J;  3CC2 H;  3PAJ A;  1VQ6 H;  1V97 A;  5DM7 J;  3C2E A;  2PA2 A;  5AYZ A;  1VQ8 H;  1VQ9 H;  1FIQ C;  3AMZ A;  1YIT H;  1WKI A;  2B7P A;  2B7N A;  4XR5 A;  1N5X A;  1S72 H;  4YYY A;  1VDV A;  3PIO J;  3CME H;  4US8 A;  4KWV A;  3CCJ H;  4USA A;  4WFB J;  1JJ2 H;  2ZJR J;  4LHM A;  4IOA J;  1FFU B; 
#chains in the Genus database with same CATH homology
 1YIJ H;  1KQS H;  4WF9 J;  1YJ9 H;  1VQ4 H;  1VQK H;  3CCQ H;  1KD1 J;  1M1K J;  1QVG H;  3DLL J;  1VQ5 H;  1VQN H;  3CD6 H;  2ZJQ J;  3G4S H;  1W2B H;  1VQL H;  1K8A J;  4IO9 J;  1N8R J;  4UY8 M;  1K73 J;  1VQ7 H;  1VQO H;  1YHQ H;  3CPW H;  3G6E H;  3I55 H;  1YJN H;  3CCM H;  4WFA J;  3CCU H;  5MLC O;  3CCR H;  1YI2 H;  5DM6 J;  3PIP J;  2OTJ H;  5H1S O;  1M90 J;  5GAH N;  1K9M J;  5GAG N;  3I56 H;  2OTL H;  1KC8 J;  5JVG J;  1VQP H;  2ZJP J;  1NJI J;  3CC7 H;  3CC4 H;  1Q86 J;  5GAE N;  1Q82 J;  5HL7 J;  4U67 J;  1YJW H;  3CCL H;  2QA4 H;  3CCS H;  1VQM H;  5GAD N;  3CMA H;  2QEX H;  3CCE H;  4IOC J;  4WFN J;  3CF5 J;  3OW2 H;  3J7Z M;  3CCV H;  3G71 H;  1Y69 K;  3CXC H;  4WCE J;  1Q7Y J;  5AN9 F;  1QVF H;  1Q81 J;  5JVH J;  3CC2 H;  1VQ6 H;  5DM7 J;  2PA2 A;  1VQ8 H;  1VQ9 H;  1YIT H;  1WKI A;  1S72 H;  3PIO J;  3CME H;  3CCJ H;  4WFB J;  1JJ2 H;  2ZJR J;  4IOA J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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