3CXCH

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
167
structure length
156
Chain Sequence
KPGAMYRNSSKPAYTRREYISGIPGKKIAQFDMGNNGAGPTYPAQVELVVEKPVQIRHNALEAARVAANRYVQNSGAAANYKFRIRKFPFHVIRENKDGMRAPFGKPVGTAARVHGANHIFIAWVNPDPNVEEAWRRAKMKVTPTINIDSSPAGNA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 27
structure length 156
sequence length 167
ec nomenclature
pdb deposition date 2008-04-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3cxcH00
2PA2A 1VQLH 1VQ9H 3CCVH 5GAGN 5JVGJ 1KD1J 1JJ2H 1M90J 1Q82J 1Y69K 1Q86J 1YIJH 1K73J 4WFBJ 5HL7J 1YJNH 2ZJQJ 2OTJH 3G4SH 2OTLH 1M1KJ 1VQPH 5MLCO 4WF9J 1N8RJ 3CCUH 1YI2H 1Q81J 3CMAH 1KQSH 4IOCJ 1Q7YJ 1VQ8H 1QVFH 2ZJRJ 4WFAJ 1KC8J 1VQ6H 1VQNH 3CF5J 3CMEH 1NJIJ 4IO9J 3G71H 1VQKH 3CCEH 3CCJH 3CC2H 1YJWH 5GAHN 1YITH 1K8AJ 2QEXH 2QA4H 4IOAJ 1W2BH 3CXCH 3CCSH 5DM6J 1QVGH 3CCMH 5JVHJ 4WFNJ 3PIOJ 5GAEN 5H1SO 4WCEJ 1YJ9H 1YHQH 1VQOH 3CCLH 1S72H 4U67J 1VQ5H 2ZJPJ 5GADN 3OW2H 3CC4H 3CCRH 3CPWH 1VQMH 3I56H 3J7ZM 3I55H 3DLLJ 5AN9F 1WKIA 3CCQH 4UY8M 3CD6H 3PIPJ 5DM7J 3G6EH 1VQ4H 3CC7H 1K9MJ 1VQ7H
chains in the Genus database with same CATH superfamily
1FM0E 3ETRC 4YEKA 2PA2A 1N5WB 4AP8A 1N61B 4I9AA 4KWWA 5AYXA 1N60B 1VQLH 4X46A 1VQ9H 5HUOA 1YTEA 3CCVH 5GAGN 5JVGJ 1BRWA 2WP4A 1UOUA 3NVVC 1KD1J 1JJ2H 1QPNA 1M90J 1Q82J 1Y69K 1Q86J 1WYGA 3GNNA 3BIIE 4GA4A 1YIJH 1K73J 4WFBJ 1SB3A 4USAA 4EADA 5HL7J 1DGJA 3NRZC 1V97A 4ZOHA 1ZXIB 1YJNH 2B7NA 3TQVA 4EAFA 1QPRA 3SR6C 4C7ZA 2ZJQJ 2OTJH 3G4SH 2OTLH 3NS1C 5MLCO 1VQPH 4WF9J 3CCUH 1N8RJ 1YI2H 1M1KJ 1YTKA 5HUPA 3C2RA 3B9JC 5EP8A 4C7YA 1Q81J 3CMAH 1KQSH 2Q5WE 4IOCJ 1JROB 3NVYC 1Q7YJ 3WO1A 3PAJA 1VQ8H 1QVFH 3AM9A 2W3RB 2ZJRJ 4WFAJ 1AZYA 1KC8J 4GA6A 1VQ6H 1YTDA 1VQNH 1N5XA 3CF5J 3CMEH 5AYYA 3AMZA 1NJIJ 4KWVA 2OMDA 4IO9J 3WNZA 3G71H 1JRPB 1VQKH 2B7PA 4GA5A 2J0FA 3VMMA 2TPTA 3CCEH 3CCJH 2W3SB 1FO4A 1NVJA 3FC4A 1QPQA 3CC2H 4US9A 1YJWH 5GAHN 2JBMA 3FAHA 1FFVB 2WK6A 3RPFA 3C2EA 1YITH 3C2VA 2W54B 1FFUB 2QEXH 1K8AJ 2QA4H 4IOAJ 1W2BH 3CXCH 2W55B 3EUB4 3CCSH 4YYYA 5DM6J 3NVWC 5MPOC 5AYZA 1QVGH 3L4PA 1QPOA 2DSJA 4US8A 2QIEA 4WFNJ 2I14A 3PIOJ 3CCMH 5GAEN 5JVHJ 1FIQC 1N62B 5H1SO 4WCEJ 3L0GA 2B7QA 1YJ9H 1QAPA 1X1OA 1YHQH 1SIJA 2E3TA 3CCLH 5EY3A 4U67J 3C2OA 1VQOH 1S72H 1VDVA 1VQ5H 2ZJPJ 1FMAE 1RM6A 5HULA 5GADN 1NVIE 3OW2H 3CC4H 3CCRH 3NVZC 3CPWH 1OTPA 3C2FA 1VLBA 3H5QA 1N63B 2WK5A 4C80A 4XR5A 1VQMH 3I56H 3J7ZM 3I55H 3DLLJ 1WKIA 3AN1A 5AN9F 3CCQH 4UY8M 3CD6H 3PIPJ 5DM7J 3G6EH 3WO0A 1VQ4H 3CC7H 2I1OA 1K9MJ 1VQ7H 1O4UA 4LHMA
chains in the Genus database with same CATH topology
2PA2A 1VQLH 1VQ9H 3CCVH 5GAGN 5JVGJ 1KD1J 1JJ2H 1M90J 1Q82J 1Y69K 1Q86J 1YIJH 1K73J 4WFBJ 5HL7J 1YJNH 2ZJQJ 2OTJH 3G4SH 2OTLH 1M1KJ 1VQPH 5MLCO 4WF9J 1N8RJ 3CCUH 1YI2H 1Q81J 3CMAH 1KQSH 4IOCJ 1Q7YJ 1VQ8H 1QVFH 2ZJRJ 4WFAJ 1KC8J 1VQ6H 1VQNH 3CF5J 3CMEH 1NJIJ 4IO9J 3G71H 1VQKH 3CCEH 3CCJH 3CC2H 1YJWH 5GAHN 1YITH 1K8AJ 2QEXH 2QA4H 4IOAJ 1W2BH 3CXCH 3CCSH 5DM6J 1QVGH 3CCMH 5JVHJ 4WFNJ 3PIOJ 5GAEN 5H1SO 4WCEJ 1YJ9H 1YHQH 1VQOH 3CCLH 1S72H 4U67J 1VQ5H 2ZJPJ 5GADN 3OW2H 3CC4H 3CCRH 3CPWH 1VQMH 3I56H 3J7ZM 3I55H 3DLLJ 5AN9F 1WKIA 3CCQH 4UY8M 3CD6H 3PIPJ 5DM7J 3G6EH 1VQ4H 3CC7H 1K9MJ 1VQ7H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PA2 A;  1VQL H;  1VQ9 H;  3CCV H;  5GAG N;  5JVG J;  1KD1 J;  1JJ2 H;  1M90 J;  1Q82 J;  1Y69 K;  1Q86 J;  1YIJ H;  1K73 J;  4WFB J;  5HL7 J;  1YJN H;  2ZJQ J;  2OTJ H;  3G4S H;  2OTL H;  1M1K J;  1VQP H;  5MLC O;  4WF9 J;  1N8R J;  3CCU H;  1YI2 H;  1Q81 J;  3CMA H;  1KQS H;  4IOC J;  1Q7Y J;  1VQ8 H;  1QVF H;  2ZJR J;  4WFA J;  1KC8 J;  1VQ6 H;  1VQN H;  3CF5 J;  3CME H;  1NJI J;  4IO9 J;  3G71 H;  1VQK H;  3CCE H;  3CCJ H;  3CC2 H;  1YJW H;  5GAH N;  1YIT H;  1K8A J;  2QEX H;  2QA4 H;  4IOA J;  1W2B H;  3CXC H;  3CCS H;  5DM6 J;  1QVG H;  3CCM H;  5JVH J;  4WFN J;  3PIO J;  5GAE N;  5H1S O;  4WCE J;  1YJ9 H;  1YHQ H;  1VQO H;  3CCL H;  1S72 H;  4U67 J;  1VQ5 H;  2ZJP J;  5GAD N;  3OW2 H;  3CC4 H;  3CCR H;  3CPW H;  1VQM H;  3I56 H;  3J7Z M;  3I55 H;  3DLL J;  5AN9 F;  1WKI A;  3CCQ H;  4UY8 M;  3CD6 H;  3PIP J;  5DM7 J;  3G6E H;  1VQ4 H;  3CC7 H;  1K9M J;  1VQ7 H; 
#chains in the Genus database with same CATH topology
 1FM0 E;  3ETR C;  4YEK A;  2PA2 A;  1N5W B;  4AP8 A;  1N61 B;  4I9A A;  4KWW A;  5AYX A;  1N60 B;  1VQL H;  4X46 A;  1VQ9 H;  5HUO A;  1YTE A;  3CCV H;  5GAG N;  5JVG J;  1BRW A;  2WP4 A;  1UOU A;  3NVV C;  1KD1 J;  1JJ2 H;  1QPN A;  1M90 J;  1Q82 J;  1Y69 K;  1Q86 J;  1WYG A;  3GNN A;  3BII E;  4GA4 A;  1YIJ H;  1K73 J;  4WFB J;  1SB3 A;  4USA A;  4EAD A;  5HL7 J;  1DGJ A;  3NRZ C;  1V97 A;  4ZOH A;  1ZXI B;  1YJN H;  2B7N A;  3TQV A;  4EAF A;  1QPR A;  3SR6 C;  4C7Z A;  2ZJQ J;  2OTJ H;  3G4S H;  2OTL H;  3NS1 C;  5MLC O;  1VQP H;  4WF9 J;  3CCU H;  1N8R J;  1YI2 H;  1M1K J;  1YTK A;  5HUP A;  3C2R A;  3B9J C;  5EP8 A;  4C7Y A;  1Q81 J;  3CMA H;  1KQS H;  2Q5W E;  4IOC J;  1JRO B;  3NVY C;  1Q7Y J;  3WO1 A;  3PAJ A;  1VQ8 H;  1QVF H;  3AM9 A;  2W3R B;  2ZJR J;  4WFA J;  1AZY A;  1KC8 J;  4GA6 A;  1VQ6 H;  1YTD A;  1VQN H;  1N5X A;  3CF5 J;  3CME H;  5AYY A;  3AMZ A;  1NJI J;  4KWV A;  2OMD A;  4IO9 J;  3WNZ A;  3G71 H;  1JRP B;  1VQK H;  2B7P A;  4GA5 A;  2J0F A;  3VMM A;  2TPT A;  3CCE H;  3CCJ H;  2W3S B;  1FO4 A;  1NVJ A;  3FC4 A;  1QPQ A;  3CC2 H;  4US9 A;  1YJW H;  5GAH N;  2JBM A;  3FAH A;  1FFV B;  2WK6 A;  3RPF A;  3C2E A;  1YIT H;  3C2V A;  2W54 B;  1FFU B;  2QEX H;  1K8A J;  2QA4 H;  4IOA J;  1W2B H;  3CXC H;  2W55 B;  3EUB 4;  3CCS H;  4YYY A;  5DM6 J;  3NVW C;  5MPO C;  5AYZ A;  1QVG H;  3L4P A;  1QPO A;  2DSJ A;  4US8 A;  2QIE A;  4WFN J;  2I14 A;  3PIO J;  3CCM H;  5GAE N;  5JVH J;  1FIQ C;  1N62 B;  5H1S O;  4WCE J;  3L0G A;  2B7Q A;  1YJ9 H;  1QAP A;  1X1O A;  1YHQ H;  1SIJ A;  2E3T A;  3CCL H;  5EY3 A;  4U67 J;  3C2O A;  1VQO H;  1S72 H;  1VDV A;  1VQ5 H;  2ZJP J;  1FMA E;  1RM6 A;  5HUL A;  5GAD N;  1NVI E;  3OW2 H;  3CC4 H;  3CCR H;  3NVZ C;  3CPW H;  1OTP A;  3C2F A;  1VLB A;  3H5Q A;  1N63 B;  2WK5 A;  4C80 A;  4XR5 A;  1VQM H;  3I56 H;  3J7Z M;  3I55 H;  3DLL J;  1WKI A;  3AN1 A;  5AN9 F;  3CCQ H;  4UY8 M;  3CD6 H;  3PIP J;  5DM7 J;  3G6E H;  3WO0 A;  1VQ4 H;  3CC7 H;  2I1O A;  1K9M J;  1VQ7 H;  1O4U A;  4LHM A; 
#chains in the Genus database with same CATH homology
 2PA2 A;  1VQL H;  1VQ9 H;  3CCV H;  5GAG N;  5JVG J;  1KD1 J;  1JJ2 H;  1M90 J;  1Q82 J;  1Y69 K;  1Q86 J;  1YIJ H;  1K73 J;  4WFB J;  5HL7 J;  1YJN H;  2ZJQ J;  2OTJ H;  3G4S H;  2OTL H;  1M1K J;  1VQP H;  5MLC O;  4WF9 J;  1N8R J;  3CCU H;  1YI2 H;  1Q81 J;  3CMA H;  1KQS H;  4IOC J;  1Q7Y J;  1VQ8 H;  1QVF H;  2ZJR J;  4WFA J;  1KC8 J;  1VQ6 H;  1VQN H;  3CF5 J;  3CME H;  1NJI J;  4IO9 J;  3G71 H;  1VQK H;  3CCE H;  3CCJ H;  3CC2 H;  1YJW H;  5GAH N;  1YIT H;  1K8A J;  2QEX H;  2QA4 H;  4IOA J;  1W2B H;  3CXC H;  3CCS H;  5DM6 J;  1QVG H;  3CCM H;  5JVH J;  4WFN J;  3PIO J;  5GAE N;  5H1S O;  4WCE J;  1YJ9 H;  1YHQ H;  1VQO H;  3CCL H;  1S72 H;  4U67 J;  1VQ5 H;  2ZJP J;  5GAD N;  3OW2 H;  3CC4 H;  3CCR H;  3CPW H;  1VQM H;  3I56 H;  3J7Z M;  3I55 H;  3DLL J;  5AN9 F;  1WKI A;  3CCQ H;  4UY8 M;  3CD6 H;  3PIP J;  5DM7 J;  3G6E H;  1VQ4 H;  3CC7 H;  1K9M J;  1VQ7 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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