3PIPJ

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
136
structure length
136
Chain Sequence
KRTKFRKQFRGRMTGDAKGGDYVAFGDYGLIAMEPAWIKSNQIEACRIVMSRHFRRGGKIYIRIFPDKPVTKKPAETRMGKGKGAVEYWVSVVKPGRVMFEVAGVTEEQAKEAFRLAGHKLPIQTKMVKREVYDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 18
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
J PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3pipJ01
2OTJH 1YIJH 4IOCJ 3CCSH 5DM7J 5GAHN 1S72H 4U67J 1Y69K 2ZJQJ 3PIOJ 1KD1J 5GAEN 1YI2H 1KQSH 2QA4H 5GADN 1QVGH 4IO9J 1VQ9H 4WFBJ 1VQMH 1VQLH 5HL7J 3CMAH 3DLLJ 1YITH 3I55H 5JVGJ 1K9MJ 3CD6H 3CXCH 1VQ5H 1K8AJ 3G6EH 1Q81J 1W2BH 4WF9J 3CCJH 1M1KJ 1VQ6H 5MLCO 2ZJPJ 1JJ2H 3J7ZM 2OTLH 1VQ4H 3CMEH 1WKIA 1KC8J 3G4SH 1VQOH 1YJ9H 2ZJRJ 3PIPJ 3CCVH 4IOAJ 2PA2A 3CPWH 1M90J 3CCMH 1YJNH 4UY8M 3CCUH 1Q86J 3G71H 1QVFH 3CCEH 1K73J 1VQ7H 3CCRH 1YJWH 3CCLH 1NJIJ 1VQ8H 5GAGN 3CC7H 5AN9F 3CF5J 4WCEJ 1Q82J 5JVHJ 5H1SO 3I56H 1VQPH 4WFNJ 1YHQH 4WFAJ 1Q7YJ 3CC4H 1VQKH 1VQNH 3OW2H 2QEXH 1N8RJ 3CCQH 3CC2H 5DM6J
chains in the Genus database with same CATH superfamily
1VDVA 2OTJH 4C80A 1FMAE 3L0GA 1YIJH 3NS1C 1FFVB 2J0FA 1N60B 3AM9A 4IOCJ 1N61B 4US9A 3CCSH 1QAPA 4US8A 5HUOA 5DM7J 5GAHN 1WYGA 1S72H 1FO4A 1SB3A 4GA5A 3AN1A 1JRPB 1NVJA 1X1OA 5MPOC 4U67J 1QPRA 5AYXA 1Y69K 3NVZC 4GA4A 2ZJQJ 3PIOJ 1KD1J 3RPFA 1YTKA 3NVWC 1SIJA 5GAEN 4I9AA 1YI2H 1QPNA 1KQSH 2W55B 3FC4A 2QA4H 5GADN 1QVGH 4IO9J 1VQ9H 4WFBJ 1VQMH 2B7QA 2W3RB 2WK6A 2WP4A 1VQLH 1RM6A 4C7ZA 2WK5A 5HL7J 3CMAH 4EADA 1N62B 3DLLJ 1YITH 3I55H 5JVGJ 1K9MJ 3AMZA 3CD6H 3CXCH 3FAHA 1VQ5H 4LHMA 3NVVC 1K8AJ 1FM0E 1BRWA 4YYYA 4KWVA 3G6EH 1Q81J 1W2BH 3B9JC 3WO1A 4USAA 2I14A 2OMDA 4WF9J 3CCJH 1M1KJ 1VQ6H 5MLCO 1O4UA 2ZJPJ 4YEKA 1JJ2H 4KWWA 1QPOA 3NVYC 3J7ZM 3TQVA 2OTLH 1VQ4H 4ZOHA 1FIQC 3CMEH 2Q5WE 1WKIA 3C2EA 1KC8J 5EP8A 3G4SH 3ETRC 3VMMA 1YJ9H 1VQOH 2ZJRJ 5AYZA 1DGJA 1JROB 4AP8A 3NRZC 3PIPJ 3CCVH 3C2RA 3WNZA 4IOAJ 3PAJA 2PA2A 3CPWH 1M90J 3CCMH 1YJNH 4UY8M 4EAFA 3CCUH 1Q86J 2I1OA 5HULA 1YTEA 3G71H 1QVFH 3CCEH 1K73J 3WO0A 1VQ7H 3CCRH 1YJWH 3C2OA 2W54B 3CCLH 1NJIJ 3SR6C 1VQ8H 4X46A 4XR5A 5EY3A 1FFUB 1OTPA 3L4PA 1UOUA 5GAGN 3C2VA 3CC7H 5AN9F 3CF5J 4WCEJ 1N63B 3GNNA 1Q82J 5JVHJ 5HUPA 1NVIE 5H1SO 3I56H 3BIIE 1VQPH 1N5WB 4WFNJ 4WFAJ 1YTDA 1YHQH 2TPTA 2DSJA 1Q7YJ 1ZXIB 3CC4H 2B7PA 1VQKH 1VLBA 4GA6A 3OW2H 1AZYA 5AYYA 2QEXH 1VQNH 3C2FA 1N8RJ 2E3TA 2QIEA 2B7NA 3CCQH 3EUB4 1N5XA 2JBMA 1QPQA 1V97A 4C7YA 5DM6J 3CC2H 3H5QA 2W3SB
chains in the Genus database with same CATH topology
2OTJH 1YIJH 4IOCJ 3CCSH 5DM7J 5GAHN 1S72H 4U67J 1Y69K 2ZJQJ 3PIOJ 1KD1J 5GAEN 1YI2H 1KQSH 2QA4H 5GADN 1QVGH 4IO9J 1VQ9H 4WFBJ 1VQMH 1VQLH 5HL7J 3CMAH 3DLLJ 1YITH 3I55H 5JVGJ 1K9MJ 3CD6H 3CXCH 1VQ5H 1K8AJ 3G6EH 1Q81J 1W2BH 4WF9J 3CCJH 1M1KJ 1VQ6H 5MLCO 2ZJPJ 1JJ2H 3J7ZM 2OTLH 1VQ4H 3CMEH 1WKIA 1KC8J 3G4SH 1VQOH 1YJ9H 2ZJRJ 3PIPJ 3CCVH 4IOAJ 2PA2A 3CPWH 1M90J 3CCMH 1YJNH 4UY8M 3CCUH 1Q86J 3G71H 1QVFH 3CCEH 1K73J 1VQ7H 3CCRH 1YJWH 3CCLH 1NJIJ 1VQ8H 5GAGN 3CC7H 5AN9F 3CF5J 4WCEJ 1Q82J 5JVHJ 5H1SO 3I56H 1VQPH 4WFNJ 1YHQH 4WFAJ 1Q7YJ 3CC4H 1VQKH 1VQNH 3OW2H 2QEXH 1N8RJ 3CCQH 3CC2H 5DM6J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OTJ H;  1YIJ H;  4IOC J;  3CCS H;  5DM7 J;  5GAH N;  1S72 H;  4U67 J;  1Y69 K;  2ZJQ J;  3PIO J;  1KD1 J;  5GAE N;  1YI2 H;  1KQS H;  2QA4 H;  5GAD N;  1QVG H;  4IO9 J;  1VQ9 H;  4WFB J;  1VQM H;  1VQL H;  5HL7 J;  3CMA H;  3DLL J;  1YIT H;  3I55 H;  5JVG J;  1K9M J;  3CD6 H;  3CXC H;  1VQ5 H;  1K8A J;  3G6E H;  1Q81 J;  1W2B H;  4WF9 J;  3CCJ H;  1M1K J;  1VQ6 H;  5MLC O;  2ZJP J;  1JJ2 H;  3J7Z M;  2OTL H;  1VQ4 H;  3CME H;  1WKI A;  1KC8 J;  3G4S H;  1VQO H;  1YJ9 H;  2ZJR J;  3PIP J;  3CCV H;  4IOA J;  2PA2 A;  3CPW H;  1M90 J;  3CCM H;  1YJN H;  4UY8 M;  3CCU H;  1Q86 J;  3G71 H;  1QVF H;  3CCE H;  1K73 J;  1VQ7 H;  3CCR H;  1YJW H;  3CCL H;  1NJI J;  1VQ8 H;  5GAG N;  3CC7 H;  5AN9 F;  3CF5 J;  4WCE J;  1Q82 J;  5JVH J;  5H1S O;  3I56 H;  1VQP H;  4WFN J;  1YHQ H;  4WFA J;  1Q7Y J;  3CC4 H;  1VQK H;  1VQN H;  3OW2 H;  2QEX H;  1N8R J;  3CCQ H;  3CC2 H;  5DM6 J; 
#chains in the Genus database with same CATH topology
 1VDV A;  2OTJ H;  4C80 A;  1FMA E;  3L0G A;  1YIJ H;  3NS1 C;  1FFV B;  2J0F A;  1N60 B;  3AM9 A;  4IOC J;  1N61 B;  4US9 A;  3CCS H;  1QAP A;  4US8 A;  5HUO A;  5DM7 J;  5GAH N;  1WYG A;  1S72 H;  1FO4 A;  1SB3 A;  4GA5 A;  3AN1 A;  1JRP B;  1NVJ A;  1X1O A;  5MPO C;  4U67 J;  1QPR A;  5AYX A;  1Y69 K;  3NVZ C;  4GA4 A;  2ZJQ J;  3PIO J;  1KD1 J;  3RPF A;  1YTK A;  3NVW C;  1SIJ A;  5GAE N;  4I9A A;  1YI2 H;  1QPN A;  1KQS H;  2W55 B;  3FC4 A;  2QA4 H;  5GAD N;  1QVG H;  4IO9 J;  1VQ9 H;  4WFB J;  1VQM H;  2B7Q A;  2W3R B;  2WK6 A;  2WP4 A;  1VQL H;  1RM6 A;  4C7Z A;  2WK5 A;  5HL7 J;  3CMA H;  4EAD A;  1N62 B;  3DLL J;  1YIT H;  3I55 H;  5JVG J;  1K9M J;  3AMZ A;  3CD6 H;  3CXC H;  3FAH A;  1VQ5 H;  4LHM A;  3NVV C;  1K8A J;  1FM0 E;  1BRW A;  4YYY A;  4KWV A;  3G6E H;  1Q81 J;  1W2B H;  3B9J C;  3WO1 A;  4USA A;  2I14 A;  2OMD A;  4WF9 J;  3CCJ H;  1M1K J;  1VQ6 H;  5MLC O;  1O4U A;  2ZJP J;  4YEK A;  1JJ2 H;  4KWW A;  1QPO A;  3NVY C;  3J7Z M;  3TQV A;  2OTL H;  1VQ4 H;  4ZOH A;  1FIQ C;  3CME H;  2Q5W E;  1WKI A;  3C2E A;  1KC8 J;  5EP8 A;  3G4S H;  3ETR C;  3VMM A;  1YJ9 H;  1VQO H;  2ZJR J;  5AYZ A;  1DGJ A;  1JRO B;  4AP8 A;  3NRZ C;  3PIP J;  3CCV H;  3C2R A;  3WNZ A;  4IOA J;  3PAJ A;  2PA2 A;  3CPW H;  1M90 J;  3CCM H;  1YJN H;  4UY8 M;  4EAF A;  3CCU H;  1Q86 J;  2I1O A;  5HUL A;  1YTE A;  3G71 H;  1QVF H;  3CCE H;  1K73 J;  3WO0 A;  1VQ7 H;  3CCR H;  1YJW H;  3C2O A;  2W54 B;  3CCL H;  1NJI J;  3SR6 C;  1VQ8 H;  4X46 A;  4XR5 A;  5EY3 A;  1FFU B;  1OTP A;  3L4P A;  1UOU A;  5GAG N;  3C2V A;  3CC7 H;  5AN9 F;  3CF5 J;  4WCE J;  1N63 B;  3GNN A;  1Q82 J;  5JVH J;  5HUP A;  1NVI E;  5H1S O;  3I56 H;  3BII E;  1VQP H;  1N5W B;  4WFN J;  4WFA J;  1YTD A;  1YHQ H;  2TPT A;  2DSJ A;  1Q7Y J;  1ZXI B;  3CC4 H;  2B7P A;  1VQK H;  1VLB A;  4GA6 A;  3OW2 H;  1AZY A;  5AYY A;  2QEX H;  1VQN H;  3C2F A;  1N8R J;  2E3T A;  2QIE A;  2B7N A;  3CCQ H;  3EUB 4;  1N5X A;  2JBM A;  1QPQ A;  1V97 A;  4C7Y A;  5DM6 J;  3CC2 H;  3H5Q A;  2W3S B; 
#chains in the Genus database with same CATH homology
 2OTJ H;  1YIJ H;  4IOC J;  3CCS H;  5DM7 J;  5GAH N;  1S72 H;  4U67 J;  1Y69 K;  2ZJQ J;  3PIO J;  1KD1 J;  5GAE N;  1YI2 H;  1KQS H;  2QA4 H;  5GAD N;  1QVG H;  4IO9 J;  1VQ9 H;  4WFB J;  1VQM H;  1VQL H;  5HL7 J;  3CMA H;  3DLL J;  1YIT H;  3I55 H;  5JVG J;  1K9M J;  3CD6 H;  3CXC H;  1VQ5 H;  1K8A J;  3G6E H;  1Q81 J;  1W2B H;  4WF9 J;  3CCJ H;  1M1K J;  1VQ6 H;  5MLC O;  2ZJP J;  1JJ2 H;  3J7Z M;  2OTL H;  1VQ4 H;  3CME H;  1WKI A;  1KC8 J;  3G4S H;  1VQO H;  1YJ9 H;  2ZJR J;  3PIP J;  3CCV H;  4IOA J;  2PA2 A;  3CPW H;  1M90 J;  3CCM H;  1YJN H;  4UY8 M;  3CCU H;  1Q86 J;  3G71 H;  1QVF H;  3CCE H;  1K73 J;  1VQ7 H;  3CCR H;  1YJW H;  3CCL H;  1NJI J;  1VQ8 H;  5GAG N;  3CC7 H;  5AN9 F;  3CF5 J;  4WCE J;  1Q82 J;  5JVH J;  5H1S O;  3I56 H;  1VQP H;  4WFN J;  1YHQ H;  4WFA J;  1Q7Y J;  3CC4 H;  1VQK H;  1VQN H;  3OW2 H;  2QEX H;  1N8R J;  3CCQ H;  3CC2 H;  5DM6 J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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