3CC4H

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 35
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3cc4H00
1VQ6H 3CCQH 4IOCJ 2ZJRJ 5AN9F 1JJ2H 4WFNJ 3G71H 3CXCH 3CCEH 1KC8J 1NJIJ 1YI2H 5JVGJ 1YJWH 4WFBJ 1QVGH 3CCUH 3DLLJ 3I56H 1S72H 1K9MJ 3PIOJ 3CMAH 1YJNH 5GADN 3PIPJ 5GAHN 1KQSH 1VQ5H 1Y69K 3CCJH 2OTJH 3CCRH 1YIJH 1VQNH 1Q81J 2QEXH 3CCSH 1VQMH 5HL7J 2ZJQJ 3G4SH 3OW2H 1VQPH 1WKIA 3CC4H 1W2BH 5GAGN 1QVFH 5DM7J 4WF9J 2OTLH 4WCEJ 1K8AJ 5DM6J 3J7ZM 1K73J 1YHQH 1VQLH 1VQOH 3CF5J 3G6EH 4UY8M 5MLCO 1VQKH 4IOAJ 3CCVH 1VQ8H 3CCLH 3CC7H 1VQ9H 3I55H 4WFAJ 1YITH 5JVHJ 1YJ9H 2QA4H 1KD1J 3CD6H 5GAEN 1VQ4H 4IO9J 1M1KJ 2ZJPJ 5H1SO 1N8RJ 1Q82J 1Q86J 3CMEH 3CC2H 3CCMH 2PA2A 3CPWH 1M90J 1Q7YJ 4U67J 1VQ7H
chains in the Genus database with same CATH superfamily
1JROB 1VLBA 4US8A 2E3TA 2OMDA 1FO4A 1VQ6H 4KWWA 2QIEA 4X46A 3CCQH 1YTEA 4IOCJ 2ZJRJ 5AN9F 3NVYC 1JJ2H 4WFNJ 1OTPA 3G71H 2I1OA 1WYGA 2TPTA 1N5XA 5AYXA 4C7ZA 3CXCH 3CCEH 3RPFA 1YTKA 1N63B 3NVVC 4GA4A 3C2RA 1KC8J 1ZXIB 3GNNA 1O4UA 3TQVA 1NJIJ 3NS1C 1YI2H 5JVGJ 3WNZA 1N5WB 1YJWH 4WFBJ 1QVGH 4C7YA 3CCUH 1FFVB 3DLLJ 2JBMA 2WK6A 3I56H 1S72H 1K9MJ 3AN1A 5AYZA 3PIOJ 3CMAH 1X1OA 1YJNH 5GADN 3PIPJ 5GAHN 1KQSH 1NVJA 1V97A 1Y69K 1VQ5H 5EY3A 2J0FA 3CCJH 3WO1A 2B7NA 3ETRC 3VMMA 2OTJH 1UOUA 2W55B 3CCRH 4YEKA 3WO0A 1YIJH 3EUB4 3C2OA 1Q81J 1VQNH 4EADA 2QEXH 3CCSH 1VQMH 5HL7J 2ZJQJ 2WP4A 3G4SH 4GA6A 3OW2H 1VQPH 1WKIA 4C80A 3CC4H 1W2BH 4LHMA 4USAA 1VDVA 3AM9A 5GAGN 1NVIE 2WK5A 5EP8A 3PAJA 3L4PA 1QVFH 3FC4A 1FFUB 5DM7J 3L0GA 1YTDA 4WF9J 1QPNA 1AZYA 2W3RB 3NRZC 3NVWC 4YYYA 2OTLH 4WCEJ 4EAFA 1K8AJ 4AP8A 5HUPA 5DM6J 5AYYA 3J7ZM 1K73J 1YHQH 1VQLH 1VQOH 1FIQC 3CF5J 3G6EH 2I14A 3NVZC 4UY8M 1SIJA 5MLCO 1VQKH 3C2FA 4KWVA 4US9A 4IOAJ 1QAPA 3CCVH 1VQ8H 1SB3A 1FMAE 1DGJA 3BIIE 1N60B 3CCLH 3C2EA 1N61B 3CC7H 1VQ9H 3FAHA 1BRWA 3C2VA 4WFAJ 3I55H 5HULA 5JVHJ 3H5QA 1YJ9H 1YITH 2QA4H 5HUOA 2W54B 1QPQA 1KD1J 3CD6H 4ZOHA 5GAEN 1VQ4H 4IO9J 1M1KJ 2ZJPJ 5H1SO 1FM0E 1JRPB 1N8RJ 1Q82J 1Q86J 3CMEH 4XR5A 3CC2H 4GA5A 4I9AA 2DSJA 1N62B 3CCMH 2PA2A 1QPRA 1QPOA 2B7QA 3CPWH 1RM6A 3SR6C 1M90J 2Q5WE 1Q7YJ 2B7PA 4U67J 1VQ7H 3AMZA 5MPOC 2W3SB 3B9JC
chains in the Genus database with same CATH topology
1VQ6H 3CCQH 4IOCJ 2ZJRJ 5AN9F 1JJ2H 4WFNJ 3G71H 3CXCH 3CCEH 1KC8J 1NJIJ 1YI2H 5JVGJ 1YJWH 4WFBJ 1QVGH 3CCUH 3DLLJ 3I56H 1S72H 1K9MJ 3PIOJ 3CMAH 1YJNH 5GADN 3PIPJ 5GAHN 1KQSH 1VQ5H 1Y69K 3CCJH 2OTJH 3CCRH 1YIJH 1VQNH 1Q81J 2QEXH 3CCSH 1VQMH 5HL7J 2ZJQJ 3G4SH 3OW2H 1VQPH 1WKIA 3CC4H 1W2BH 5GAGN 1QVFH 5DM7J 4WF9J 2OTLH 4WCEJ 1K8AJ 5DM6J 3J7ZM 1K73J 1YHQH 1VQLH 1VQOH 3CF5J 3G6EH 4UY8M 5MLCO 1VQKH 4IOAJ 3CCVH 1VQ8H 3CCLH 3CC7H 1VQ9H 3I55H 4WFAJ 1YITH 5JVHJ 1YJ9H 2QA4H 1KD1J 3CD6H 5GAEN 1VQ4H 4IO9J 1M1KJ 2ZJPJ 5H1SO 1N8RJ 1Q82J 1Q86J 3CMEH 3CC2H 3CCMH 2PA2A 3CPWH 1M90J 1Q7YJ 4U67J 1VQ7H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ6 H;  3CCQ H;  4IOC J;  2ZJR J;  5AN9 F;  1JJ2 H;  4WFN J;  3G71 H;  3CXC H;  3CCE H;  1KC8 J;  1NJI J;  1YI2 H;  5JVG J;  1YJW H;  4WFB J;  1QVG H;  3CCU H;  3DLL J;  3I56 H;  1S72 H;  1K9M J;  3PIO J;  3CMA H;  1YJN H;  5GAD N;  3PIP J;  5GAH N;  1KQS H;  1VQ5 H;  1Y69 K;  3CCJ H;  2OTJ H;  3CCR H;  1YIJ H;  1VQN H;  1Q81 J;  2QEX H;  3CCS H;  1VQM H;  5HL7 J;  2ZJQ J;  3G4S H;  3OW2 H;  1VQP H;  1WKI A;  3CC4 H;  1W2B H;  5GAG N;  1QVF H;  5DM7 J;  4WF9 J;  2OTL H;  4WCE J;  1K8A J;  5DM6 J;  3J7Z M;  1K73 J;  1YHQ H;  1VQL H;  1VQO H;  3CF5 J;  3G6E H;  4UY8 M;  5MLC O;  1VQK H;  4IOA J;  3CCV H;  1VQ8 H;  3CCL H;  3CC7 H;  1VQ9 H;  3I55 H;  4WFA J;  1YIT H;  5JVH J;  1YJ9 H;  2QA4 H;  1KD1 J;  3CD6 H;  5GAE N;  1VQ4 H;  4IO9 J;  1M1K J;  2ZJP J;  5H1S O;  1N8R J;  1Q82 J;  1Q86 J;  3CME H;  3CC2 H;  3CCM H;  2PA2 A;  3CPW H;  1M90 J;  1Q7Y J;  4U67 J;  1VQ7 H; 
#chains in the Genus database with same CATH topology
 1JRO B;  1VLB A;  4US8 A;  2E3T A;  2OMD A;  1FO4 A;  1VQ6 H;  4KWW A;  2QIE A;  4X46 A;  3CCQ H;  1YTE A;  4IOC J;  2ZJR J;  5AN9 F;  3NVY C;  1JJ2 H;  4WFN J;  1OTP A;  3G71 H;  2I1O A;  1WYG A;  2TPT A;  1N5X A;  5AYX A;  4C7Z A;  3CXC H;  3CCE H;  3RPF A;  1YTK A;  1N63 B;  3NVV C;  4GA4 A;  3C2R A;  1KC8 J;  1ZXI B;  3GNN A;  1O4U A;  3TQV A;  1NJI J;  3NS1 C;  1YI2 H;  5JVG J;  3WNZ A;  1N5W B;  1YJW H;  4WFB J;  1QVG H;  4C7Y A;  3CCU H;  1FFV B;  3DLL J;  2JBM A;  2WK6 A;  3I56 H;  1S72 H;  1K9M J;  3AN1 A;  5AYZ A;  3PIO J;  3CMA H;  1X1O A;  1YJN H;  5GAD N;  3PIP J;  5GAH N;  1KQS H;  1NVJ A;  1V97 A;  1Y69 K;  1VQ5 H;  5EY3 A;  2J0F A;  3CCJ H;  3WO1 A;  2B7N A;  3ETR C;  3VMM A;  2OTJ H;  1UOU A;  2W55 B;  3CCR H;  4YEK A;  3WO0 A;  1YIJ H;  3EUB 4;  3C2O A;  1Q81 J;  1VQN H;  4EAD A;  2QEX H;  3CCS H;  1VQM H;  5HL7 J;  2ZJQ J;  2WP4 A;  3G4S H;  4GA6 A;  3OW2 H;  1VQP H;  1WKI A;  4C80 A;  3CC4 H;  1W2B H;  4LHM A;  4USA A;  1VDV A;  3AM9 A;  5GAG N;  1NVI E;  2WK5 A;  5EP8 A;  3PAJ A;  3L4P A;  1QVF H;  3FC4 A;  1FFU B;  5DM7 J;  3L0G A;  1YTD A;  4WF9 J;  1QPN A;  1AZY A;  2W3R B;  3NRZ C;  3NVW C;  4YYY A;  2OTL H;  4WCE J;  4EAF A;  1K8A J;  4AP8 A;  5HUP A;  5DM6 J;  5AYY A;  3J7Z M;  1K73 J;  1YHQ H;  1VQL H;  1VQO H;  1FIQ C;  3CF5 J;  3G6E H;  2I14 A;  3NVZ C;  4UY8 M;  1SIJ A;  5MLC O;  1VQK H;  3C2F A;  4KWV A;  4US9 A;  4IOA J;  1QAP A;  3CCV H;  1VQ8 H;  1SB3 A;  1FMA E;  1DGJ A;  3BII E;  1N60 B;  3CCL H;  3C2E A;  1N61 B;  3CC7 H;  1VQ9 H;  3FAH A;  1BRW A;  3C2V A;  4WFA J;  3I55 H;  5HUL A;  5JVH J;  3H5Q A;  1YJ9 H;  1YIT H;  2QA4 H;  5HUO A;  2W54 B;  1QPQ A;  1KD1 J;  3CD6 H;  4ZOH A;  5GAE N;  1VQ4 H;  4IO9 J;  1M1K J;  2ZJP J;  5H1S O;  1FM0 E;  1JRP B;  1N8R J;  1Q82 J;  1Q86 J;  3CME H;  4XR5 A;  3CC2 H;  4GA5 A;  4I9A A;  2DSJ A;  1N62 B;  3CCM H;  2PA2 A;  1QPR A;  1QPO A;  2B7Q A;  3CPW H;  1RM6 A;  3SR6 C;  1M90 J;  2Q5W E;  1Q7Y J;  2B7P A;  4U67 J;  1VQ7 H;  3AMZ A;  5MPO C;  2W3S B;  3B9J C; 
#chains in the Genus database with same CATH homology
 1VQ6 H;  3CCQ H;  4IOC J;  2ZJR J;  5AN9 F;  1JJ2 H;  4WFN J;  3G71 H;  3CXC H;  3CCE H;  1KC8 J;  1NJI J;  1YI2 H;  5JVG J;  1YJW H;  4WFB J;  1QVG H;  3CCU H;  3DLL J;  3I56 H;  1S72 H;  1K9M J;  3PIO J;  3CMA H;  1YJN H;  5GAD N;  3PIP J;  5GAH N;  1KQS H;  1VQ5 H;  1Y69 K;  3CCJ H;  2OTJ H;  3CCR H;  1YIJ H;  1VQN H;  1Q81 J;  2QEX H;  3CCS H;  1VQM H;  5HL7 J;  2ZJQ J;  3G4S H;  3OW2 H;  1VQP H;  1WKI A;  3CC4 H;  1W2B H;  5GAG N;  1QVF H;  5DM7 J;  4WF9 J;  2OTL H;  4WCE J;  1K8A J;  5DM6 J;  3J7Z M;  1K73 J;  1YHQ H;  1VQL H;  1VQO H;  3CF5 J;  3G6E H;  4UY8 M;  5MLC O;  1VQK H;  4IOA J;  3CCV H;  1VQ8 H;  3CCL H;  3CC7 H;  1VQ9 H;  3I55 H;  4WFA J;  1YIT H;  5JVH J;  1YJ9 H;  2QA4 H;  1KD1 J;  3CD6 H;  5GAE N;  1VQ4 H;  4IO9 J;  1M1K J;  2ZJP J;  5H1S O;  1N8R J;  1Q82 J;  1Q86 J;  3CME H;  3CC2 H;  3CCM H;  2PA2 A;  3CPW H;  1M90 J;  1Q7Y J;  4U67 J;  1VQ7 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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