3CCEH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3cceH00
1M1KJ 3CC2H 1VQ5H 3CXCH 1YJWH 1W2BH 1VQMH 1VQ6H 3CCSH 1YITH 1Q81J 3PIOJ 1VQ9H 4U67J 1Y69K 1VQPH 3J7ZM 4WFNJ 3CMAH 1VQKH 1Q86J 2OTLH 2ZJRJ 1N8RJ 1YJ9H 1KC8J 4WFBJ 1K73J 1QVGH 3CCMH 4IOCJ 5DM6J 1K8AJ 2ZJQJ 3CCQH 5GADN 5JVHJ 3DLLJ 5H1SO 1K9MJ 3CMEH 3G6EH 1KQSH 3CF5J 2QEXH 1Q7YJ 3CCVH 1YIJH 1S72H 5GAHN 5AN9F 3CC7H 1VQ8H 3G4SH 3CD6H 5GAEN 1VQ7H 5HL7J 3PIPJ 5GAGN 4WCEJ 2QA4H 1VQLH 2OTJH 1KD1J 3CCJH 3CPWH 3OW2H 2PA2A 1YI2H 5JVGJ 4IO9J 3I56H 1VQNH 5DM7J 3G71H 4UY8M 3CCUH 1YJNH 1VQ4H 3CCLH 1JJ2H 4WFAJ 4IOAJ 1QVFH 5MLCO 3CC4H 4WF9J 1M90J 1WKIA 1YHQH 3I55H 1Q82J 1NJIJ 3CCEH 2ZJPJ 3CCRH 1VQOH
chains in the Genus database with same CATH superfamily
1M1KJ 3CC2H 1VQ5H 4EAFA 1UOUA 4C7ZA 3CXCH 4GA6A 4I9AA 1YJWH 3B9JC 3NS1C 4EADA 1W2BH 1VQMH 2WP4A 1VQ6H 4GA5A 3CCSH 1VDVA 1YITH 1Q81J 2TPTA 3PIOJ 3BIIE 1VQ9H 4U67J 1Y69K 5MPOC 1VQPH 1N60B 2Q5WE 3C2FA 3J7ZM 4WFNJ 2J0FA 1VLBA 3CMAH 2B7NA 1VQKH 1Q86J 1RM6A 1FM0E 3TQVA 5EY3A 3NVWC 1NVIE 2I1OA 3C2RA 3FAHA 2ZJRJ 1FO4A 2OTLH 1JROB 4C80A 1N8RJ 1YJ9H 4KWVA 1KC8J 4WFBJ 1N63B 1K73J 5EP8A 3ETRC 1QVGH 3CCMH 1QPQA 4XR5A 1WYGA 4IOCJ 5DM6J 1K8AJ 2ZJQJ 3EUB4 1FFUB 5HULA 3CCQH 5AYXA 5GADN 2DSJA 5JVHJ 1DGJA 1N62B 3DLLJ 1OTPA 1ZXIB 3GNNA 3AN1A 1SIJA 4ZOHA 5H1SO 2B7QA 1K9MJ 3CMEH 2B7PA 3G6EH 3CF5J 3NVZC 1KQSH 4US8A 1FFVB 3H5QA 2QEXH 1Q7YJ 3CCVH 1YIJH 1AZYA 1QAPA 1S72H 3RPFA 1QPOA 4GA4A 3WO0A 5GAHN 5AN9F 3SR6C 3CC7H 1NVJA 1VQ8H 2W55B 1FIQC 1N5XA 3G4SH 3CD6H 1QPRA 4US9A 1YTEA 4USAA 5GAEN 3AMZA 1VQ7H 5HL7J 3PIPJ 3L0GA 5GAGN 1YTKA 1QPNA 4WCEJ 4KWWA 3NVVC 1N61B 2WK6A 4AP8A 2QA4H 1VQLH 1KD1J 3CCJH 3CPWH 2OTJH 3OW2H 2PA2A 5AYZA 1JRPB 2QIEA 1N5WB 5JVGJ 4IO9J 1YI2H 3I56H 2JBMA 1BRWA 1O4UA 1VQNH 2W3SB 1X1OA 2E3TA 5HUPA 5DM7J 3NRZC 3WO1A 3L4PA 3G71H 3NVYC 4X46A 4UY8M 2W54B 4LHMA 1SB3A 3CCUH 1YJNH 4YYYA 5AYYA 3C2OA 1VQ4H 1V97A 3CCLH 1JJ2H 3FC4A 3C2VA 5HUOA 4WFAJ 2I14A 2WK5A 4IOAJ 1QVFH 3PAJA 3WNZA 5MLCO 1FMAE 3AM9A 3CC4H 4WF9J 1M90J 1WKIA 1YHQH 3I55H 1Q82J 1NJIJ 3CCEH 2W3RB 2ZJPJ 3VMMA 3CCRH 1YTDA 2OMDA 4C7YA 3C2EA 1VQOH 4YEKA
chains in the Genus database with same CATH topology
1M1KJ 3CC2H 1VQ5H 3CXCH 1YJWH 1W2BH 1VQMH 1VQ6H 3CCSH 1YITH 1Q81J 3PIOJ 1VQ9H 4U67J 1Y69K 1VQPH 3J7ZM 4WFNJ 3CMAH 1VQKH 1Q86J 2OTLH 2ZJRJ 1N8RJ 1YJ9H 1KC8J 4WFBJ 1K73J 1QVGH 3CCMH 4IOCJ 5DM6J 1K8AJ 2ZJQJ 3CCQH 5GADN 5JVHJ 3DLLJ 5H1SO 1K9MJ 3CMEH 3G6EH 1KQSH 3CF5J 2QEXH 1Q7YJ 3CCVH 1YIJH 1S72H 5GAHN 5AN9F 3CC7H 1VQ8H 3G4SH 3CD6H 5GAEN 1VQ7H 5HL7J 3PIPJ 5GAGN 4WCEJ 2QA4H 1VQLH 2OTJH 1KD1J 3CCJH 3CPWH 3OW2H 2PA2A 1YI2H 5JVGJ 4IO9J 3I56H 1VQNH 5DM7J 3G71H 4UY8M 3CCUH 1YJNH 1VQ4H 3CCLH 1JJ2H 4WFAJ 4IOAJ 1QVFH 5MLCO 3CC4H 4WF9J 1M90J 1WKIA 1YHQH 3I55H 1Q82J 1NJIJ 3CCEH 2ZJPJ 3CCRH 1VQOH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M1K J;  3CC2 H;  1VQ5 H;  3CXC H;  1YJW H;  1W2B H;  1VQM H;  1VQ6 H;  3CCS H;  1YIT H;  1Q81 J;  3PIO J;  1VQ9 H;  4U67 J;  1Y69 K;  1VQP H;  3J7Z M;  4WFN J;  3CMA H;  1VQK H;  1Q86 J;  2OTL H;  2ZJR J;  1N8R J;  1YJ9 H;  1KC8 J;  4WFB J;  1K73 J;  1QVG H;  3CCM H;  4IOC J;  5DM6 J;  1K8A J;  2ZJQ J;  3CCQ H;  5GAD N;  5JVH J;  3DLL J;  5H1S O;  1K9M J;  3CME H;  3G6E H;  1KQS H;  3CF5 J;  2QEX H;  1Q7Y J;  3CCV H;  1YIJ H;  1S72 H;  5GAH N;  5AN9 F;  3CC7 H;  1VQ8 H;  3G4S H;  3CD6 H;  5GAE N;  1VQ7 H;  5HL7 J;  3PIP J;  5GAG N;  4WCE J;  2QA4 H;  1VQL H;  2OTJ H;  1KD1 J;  3CCJ H;  3CPW H;  3OW2 H;  2PA2 A;  1YI2 H;  5JVG J;  4IO9 J;  3I56 H;  1VQN H;  5DM7 J;  3G71 H;  4UY8 M;  3CCU H;  1YJN H;  1VQ4 H;  3CCL H;  1JJ2 H;  4WFA J;  4IOA J;  1QVF H;  5MLC O;  3CC4 H;  4WF9 J;  1M90 J;  1WKI A;  1YHQ H;  3I55 H;  1Q82 J;  1NJI J;  3CCE H;  2ZJP J;  3CCR H;  1VQO H; 
#chains in the Genus database with same CATH topology
 1M1K J;  3CC2 H;  1VQ5 H;  4EAF A;  1UOU A;  4C7Z A;  3CXC H;  4GA6 A;  4I9A A;  1YJW H;  3B9J C;  3NS1 C;  4EAD A;  1W2B H;  1VQM H;  2WP4 A;  1VQ6 H;  4GA5 A;  3CCS H;  1VDV A;  1YIT H;  1Q81 J;  2TPT A;  3PIO J;  3BII E;  1VQ9 H;  4U67 J;  1Y69 K;  5MPO C;  1VQP H;  1N60 B;  2Q5W E;  3C2F A;  3J7Z M;  4WFN J;  2J0F A;  1VLB A;  3CMA H;  2B7N A;  1VQK H;  1Q86 J;  1RM6 A;  1FM0 E;  3TQV A;  5EY3 A;  3NVW C;  1NVI E;  2I1O A;  3C2R A;  3FAH A;  2ZJR J;  1FO4 A;  2OTL H;  1JRO B;  4C80 A;  1N8R J;  1YJ9 H;  4KWV A;  1KC8 J;  4WFB J;  1N63 B;  1K73 J;  5EP8 A;  3ETR C;  1QVG H;  3CCM H;  1QPQ A;  4XR5 A;  1WYG A;  4IOC J;  5DM6 J;  1K8A J;  2ZJQ J;  3EUB 4;  1FFU B;  5HUL A;  3CCQ H;  5AYX A;  5GAD N;  2DSJ A;  5JVH J;  1DGJ A;  1N62 B;  3DLL J;  1OTP A;  1ZXI B;  3GNN A;  3AN1 A;  1SIJ A;  4ZOH A;  5H1S O;  2B7Q A;  1K9M J;  3CME H;  2B7P A;  3G6E H;  3CF5 J;  3NVZ C;  1KQS H;  4US8 A;  1FFV B;  3H5Q A;  2QEX H;  1Q7Y J;  3CCV H;  1YIJ H;  1AZY A;  1QAP A;  1S72 H;  3RPF A;  1QPO A;  4GA4 A;  3WO0 A;  5GAH N;  5AN9 F;  3SR6 C;  3CC7 H;  1NVJ A;  1VQ8 H;  2W55 B;  1FIQ C;  1N5X A;  3G4S H;  3CD6 H;  1QPR A;  4US9 A;  1YTE A;  4USA A;  5GAE N;  3AMZ A;  1VQ7 H;  5HL7 J;  3PIP J;  3L0G A;  5GAG N;  1YTK A;  1QPN A;  4WCE J;  4KWW A;  3NVV C;  1N61 B;  2WK6 A;  4AP8 A;  2QA4 H;  1VQL H;  1KD1 J;  3CCJ H;  3CPW H;  2OTJ H;  3OW2 H;  2PA2 A;  5AYZ A;  1JRP B;  2QIE A;  1N5W B;  5JVG J;  4IO9 J;  1YI2 H;  3I56 H;  2JBM A;  1BRW A;  1O4U A;  1VQN H;  2W3S B;  1X1O A;  2E3T A;  5HUP A;  5DM7 J;  3NRZ C;  3WO1 A;  3L4P A;  3G71 H;  3NVY C;  4X46 A;  4UY8 M;  2W54 B;  4LHM A;  1SB3 A;  3CCU H;  1YJN H;  4YYY A;  5AYY A;  3C2O A;  1VQ4 H;  1V97 A;  3CCL H;  1JJ2 H;  3FC4 A;  3C2V A;  5HUO A;  4WFA J;  2I14 A;  2WK5 A;  4IOA J;  1QVF H;  3PAJ A;  3WNZ A;  5MLC O;  1FMA E;  3AM9 A;  3CC4 H;  4WF9 J;  1M90 J;  1WKI A;  1YHQ H;  3I55 H;  1Q82 J;  1NJI J;  3CCE H;  2W3R B;  2ZJP J;  3VMM A;  3CCR H;  1YTD A;  2OMD A;  4C7Y A;  3C2E A;  1VQO H;  4YEK A; 
#chains in the Genus database with same CATH homology
 1M1K J;  3CC2 H;  1VQ5 H;  3CXC H;  1YJW H;  1W2B H;  1VQM H;  1VQ6 H;  3CCS H;  1YIT H;  1Q81 J;  3PIO J;  1VQ9 H;  4U67 J;  1Y69 K;  1VQP H;  3J7Z M;  4WFN J;  3CMA H;  1VQK H;  1Q86 J;  2OTL H;  2ZJR J;  1N8R J;  1YJ9 H;  1KC8 J;  4WFB J;  1K73 J;  1QVG H;  3CCM H;  4IOC J;  5DM6 J;  1K8A J;  2ZJQ J;  3CCQ H;  5GAD N;  5JVH J;  3DLL J;  5H1S O;  1K9M J;  3CME H;  3G6E H;  1KQS H;  3CF5 J;  2QEX H;  1Q7Y J;  3CCV H;  1YIJ H;  1S72 H;  5GAH N;  5AN9 F;  3CC7 H;  1VQ8 H;  3G4S H;  3CD6 H;  5GAE N;  1VQ7 H;  5HL7 J;  3PIP J;  5GAG N;  4WCE J;  2QA4 H;  1VQL H;  2OTJ H;  1KD1 J;  3CCJ H;  3CPW H;  3OW2 H;  2PA2 A;  1YI2 H;  5JVG J;  4IO9 J;  3I56 H;  1VQN H;  5DM7 J;  3G71 H;  4UY8 M;  3CCU H;  1YJN H;  1VQ4 H;  3CCL H;  1JJ2 H;  4WFA J;  4IOA J;  1QVF H;  5MLC O;  3CC4 H;  4WF9 J;  1M90 J;  1WKI A;  1YHQ H;  3I55 H;  1Q82 J;  1NJI J;  3CCE H;  2ZJP J;  3CCR H;  1VQO H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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