3CCJH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 30
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3ccjH00
4WF9J 1Q82J 1K9MJ 2ZJRJ 3I56H 3CC4H 2QEXH 1N8RJ 4WFNJ 3CPWH 5GAGN 3J7ZM 3CCUH 5GAEN 2ZJQJ 1VQKH 2OTLH 1VQPH 3CCLH 3G6EH 1VQNH 5JVGJ 1YI2H 1KQSH 1QVFH 1NJIJ 4WFAJ 1S72H 1VQ4H 3CXCH 1K8AJ 3CCEH 1VQ6H 1YIJH 3PIPJ 3G4SH 3G71H 5DM6J 1KC8J 3OW2H 3DLLJ 4IO9J 5AN9F 5DM7J 5HL7J 4WCEJ 3CCSH 1YHQH 1YITH 1WKIA 3CC7H 5MLCO 3CF5J 2QA4H 4IOAJ 1YJNH 1Q7YJ 1M1KJ 5GAHN 1YJ9H 1W2BH 1K73J 3CC2H 1VQ7H 3CD6H 3PIOJ 3CCJH 2PA2A 5JVHJ 3CCVH 1KD1J 1JJ2H 1Q81J 1VQ9H 3CCQH 1VQ8H 5H1SO 1VQOH 1YJWH 1VQ5H 4IOCJ 3I55H 5GADN 2OTJH 1Q86J 3CCMH 4U67J 2ZJPJ 1M90J 1Y69K 3CMAH 1VQMH 3CMEH 1QVGH 1VQLH 3CCRH 4UY8M 4WFBJ
chains in the Genus database with same CATH superfamily
4WF9J 1Q82J 5HUOA 1DGJA 4EAFA 1NVJA 1K9MJ 2ZJRJ 3C2VA 1SB3A 3I56H 3NVZC 3CC4H 4C80A 2QEXH 1N8RJ 1YTEA 1SIJA 3AM9A 4WFNJ 3CPWH 5GAGN 1QPNA 3J7ZM 3NVWC 3CCUH 3B9JC 4XR5A 3NVYC 5GAEN 2ZJQJ 1VQKH 2OTLH 1VQPH 2WP4A 3CCLH 3G6EH 2JBMA 1NVIE 4I9AA 1WYGA 3AN1A 1VQNH 2TPTA 5JVGJ 3C2OA 1YI2H 1KQSH 1N5XA 1FFVB 4C7YA 2W55B 5HUPA 2OMDA 1OTPA 1V97A 5EY3A 1VLBA 1QVFH 1NJIJ 1N60B 4WFAJ 1YTKA 1S72H 1VQ4H 2W3RB 3AMZA 3CXCH 1QPOA 1UOUA 2DSJA 3C2EA 3CCEH 1K8AJ 3ETRC 1VQ6H 4US8A 1YIJH 4USAA 2I1OA 1X1OA 1JRPB 3PIPJ 3G4SH 2Q5WE 1N63B 3G71H 5DM6J 1KC8J 2J0FA 4GA4A 3NVVC 3OW2H 3L4PA 2WK6A 4YEKA 4EADA 3WNZA 3DLLJ 4IO9J 3PAJA 5AN9F 1AZYA 2W54B 5DM7J 5HL7J 4WCEJ 4AP8A 1QAPA 5MPOC 3CCSH 2B7NA 3EUB4 5EP8A 2WK5A 1VDVA 2B7PA 1N61B 1RM6A 1WKIA 3C2RA 1YHQH 1YITH 3TQVA 3CC7H 5MLCO 3CF5J 5AYXA 3FC4A 3NS1C 4ZOHA 3WO1A 2QA4H 4IOAJ 1YJNH 1Q7YJ 1M1KJ 3GNNA 2QIEA 3SR6C 5GAHN 1YJ9H 1W2BH 5AYZA 1K73J 3CC2H 1FMAE 1VQ7H 4KWVA 4YYYA 2B7QA 3CD6H 3PIOJ 3CCJH 2PA2A 5JVHJ 1N5WB 1FO4A 3CCVH 3VMMA 4LHMA 1KD1J 1O4UA 1JJ2H 4X46A 1Q81J 2E3TA 1QPRA 1VQ9H 3CCQH 1VQ8H 5H1SO 1BRWA 1JROB 1VQOH 1QPQA 3H5QA 1FFUB 5HULA 1YJWH 1ZXIB 1VQ5H 4IOCJ 3L0GA 3FAHA 3I55H 5GADN 3C2FA 4GA5A 1Q86J 2OTJH 1FIQC 5AYYA 3CCMH 2I14A 4GA6A 4U67J 4C7ZA 2ZJPJ 4KWWA 1N62B 1M90J 3BIIE 1Y69K 3CMAH 1YTDA 3NRZC 3WO0A 1VQMH 3CMEH 1QVGH 4US9A 1VQLH 2W3SB 3RPFA 3CCRH 4UY8M 1FM0E 4WFBJ
chains in the Genus database with same CATH topology
4WF9J 1Q82J 1K9MJ 2ZJRJ 3I56H 3CC4H 2QEXH 1N8RJ 4WFNJ 3CPWH 5GAGN 3J7ZM 3CCUH 5GAEN 2ZJQJ 1VQKH 2OTLH 1VQPH 3CCLH 3G6EH 1VQNH 5JVGJ 1YI2H 1KQSH 1QVFH 1NJIJ 4WFAJ 1S72H 1VQ4H 3CXCH 1K8AJ 3CCEH 1VQ6H 1YIJH 3PIPJ 3G4SH 3G71H 5DM6J 1KC8J 3OW2H 3DLLJ 4IO9J 5AN9F 5DM7J 5HL7J 4WCEJ 3CCSH 1YHQH 1YITH 1WKIA 3CC7H 5MLCO 3CF5J 2QA4H 4IOAJ 1YJNH 1Q7YJ 1M1KJ 5GAHN 1YJ9H 1W2BH 1K73J 3CC2H 1VQ7H 3CD6H 3PIOJ 3CCJH 2PA2A 5JVHJ 3CCVH 1KD1J 1JJ2H 1Q81J 1VQ9H 3CCQH 1VQ8H 5H1SO 1VQOH 1YJWH 1VQ5H 4IOCJ 3I55H 5GADN 2OTJH 1Q86J 3CCMH 4U67J 2ZJPJ 1M90J 1Y69K 3CMAH 1VQMH 3CMEH 1QVGH 1VQLH 3CCRH 4UY8M 4WFBJ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WF9 J;  1Q82 J;  1K9M J;  2ZJR J;  3I56 H;  3CC4 H;  2QEX H;  1N8R J;  4WFN J;  3CPW H;  5GAG N;  3J7Z M;  3CCU H;  5GAE N;  2ZJQ J;  1VQK H;  2OTL H;  1VQP H;  3CCL H;  3G6E H;  1VQN H;  5JVG J;  1YI2 H;  1KQS H;  1QVF H;  1NJI J;  4WFA J;  1S72 H;  1VQ4 H;  3CXC H;  1K8A J;  3CCE H;  1VQ6 H;  1YIJ H;  3PIP J;  3G4S H;  3G71 H;  5DM6 J;  1KC8 J;  3OW2 H;  3DLL J;  4IO9 J;  5AN9 F;  5DM7 J;  5HL7 J;  4WCE J;  3CCS H;  1YHQ H;  1YIT H;  1WKI A;  3CC7 H;  5MLC O;  3CF5 J;  2QA4 H;  4IOA J;  1YJN H;  1Q7Y J;  1M1K J;  5GAH N;  1YJ9 H;  1W2B H;  1K73 J;  3CC2 H;  1VQ7 H;  3CD6 H;  3PIO J;  3CCJ H;  2PA2 A;  5JVH J;  3CCV H;  1KD1 J;  1JJ2 H;  1Q81 J;  1VQ9 H;  3CCQ H;  1VQ8 H;  5H1S O;  1VQO H;  1YJW H;  1VQ5 H;  4IOC J;  3I55 H;  5GAD N;  2OTJ H;  1Q86 J;  3CCM H;  4U67 J;  2ZJP J;  1M90 J;  1Y69 K;  3CMA H;  1VQM H;  3CME H;  1QVG H;  1VQL H;  3CCR H;  4UY8 M;  4WFB J; 
#chains in the Genus database with same CATH topology
 4WF9 J;  1Q82 J;  5HUO A;  1DGJ A;  4EAF A;  1NVJ A;  1K9M J;  2ZJR J;  3C2V A;  1SB3 A;  3I56 H;  3NVZ C;  3CC4 H;  4C80 A;  2QEX H;  1N8R J;  1YTE A;  1SIJ A;  3AM9 A;  4WFN J;  3CPW H;  5GAG N;  1QPN A;  3J7Z M;  3NVW C;  3CCU H;  3B9J C;  4XR5 A;  3NVY C;  5GAE N;  2ZJQ J;  1VQK H;  2OTL H;  1VQP H;  2WP4 A;  3CCL H;  3G6E H;  2JBM A;  1NVI E;  4I9A A;  1WYG A;  3AN1 A;  1VQN H;  2TPT A;  5JVG J;  3C2O A;  1YI2 H;  1KQS H;  1N5X A;  1FFV B;  4C7Y A;  2W55 B;  5HUP A;  2OMD A;  1OTP A;  1V97 A;  5EY3 A;  1VLB A;  1QVF H;  1NJI J;  1N60 B;  4WFA J;  1YTK A;  1S72 H;  1VQ4 H;  2W3R B;  3AMZ A;  3CXC H;  1QPO A;  1UOU A;  2DSJ A;  3C2E A;  3CCE H;  1K8A J;  3ETR C;  1VQ6 H;  4US8 A;  1YIJ H;  4USA A;  2I1O A;  1X1O A;  1JRP B;  3PIP J;  3G4S H;  2Q5W E;  1N63 B;  3G71 H;  5DM6 J;  1KC8 J;  2J0F A;  4GA4 A;  3NVV C;  3OW2 H;  3L4P A;  2WK6 A;  4YEK A;  4EAD A;  3WNZ A;  3DLL J;  4IO9 J;  3PAJ A;  5AN9 F;  1AZY A;  2W54 B;  5DM7 J;  5HL7 J;  4WCE J;  4AP8 A;  1QAP A;  5MPO C;  3CCS H;  2B7N A;  3EUB 4;  5EP8 A;  2WK5 A;  1VDV A;  2B7P A;  1N61 B;  1RM6 A;  1WKI A;  3C2R A;  1YHQ H;  1YIT H;  3TQV A;  3CC7 H;  5MLC O;  3CF5 J;  5AYX A;  3FC4 A;  3NS1 C;  4ZOH A;  3WO1 A;  2QA4 H;  4IOA J;  1YJN H;  1Q7Y J;  1M1K J;  3GNN A;  2QIE A;  3SR6 C;  5GAH N;  1YJ9 H;  1W2B H;  5AYZ A;  1K73 J;  3CC2 H;  1FMA E;  1VQ7 H;  4KWV A;  4YYY A;  2B7Q A;  3CD6 H;  3PIO J;  3CCJ H;  2PA2 A;  5JVH J;  1N5W B;  1FO4 A;  3CCV H;  3VMM A;  4LHM A;  1KD1 J;  1O4U A;  1JJ2 H;  4X46 A;  1Q81 J;  2E3T A;  1QPR A;  1VQ9 H;  3CCQ H;  1VQ8 H;  5H1S O;  1BRW A;  1JRO B;  1VQO H;  1QPQ A;  3H5Q A;  1FFU B;  5HUL A;  1YJW H;  1ZXI B;  1VQ5 H;  4IOC J;  3L0G A;  3FAH A;  3I55 H;  5GAD N;  3C2F A;  4GA5 A;  1Q86 J;  2OTJ H;  1FIQ C;  5AYY A;  3CCM H;  2I14 A;  4GA6 A;  4U67 J;  4C7Z A;  2ZJP J;  4KWW A;  1N62 B;  1M90 J;  3BII E;  1Y69 K;  3CMA H;  1YTD A;  3NRZ C;  3WO0 A;  1VQM H;  3CME H;  1QVG H;  4US9 A;  1VQL H;  2W3S B;  3RPF A;  3CCR H;  4UY8 M;  1FM0 E;  4WFB J; 
#chains in the Genus database with same CATH homology
 4WF9 J;  1Q82 J;  1K9M J;  2ZJR J;  3I56 H;  3CC4 H;  2QEX H;  1N8R J;  4WFN J;  3CPW H;  5GAG N;  3J7Z M;  3CCU H;  5GAE N;  2ZJQ J;  1VQK H;  2OTL H;  1VQP H;  3CCL H;  3G6E H;  1VQN H;  5JVG J;  1YI2 H;  1KQS H;  1QVF H;  1NJI J;  4WFA J;  1S72 H;  1VQ4 H;  3CXC H;  1K8A J;  3CCE H;  1VQ6 H;  1YIJ H;  3PIP J;  3G4S H;  3G71 H;  5DM6 J;  1KC8 J;  3OW2 H;  3DLL J;  4IO9 J;  5AN9 F;  5DM7 J;  5HL7 J;  4WCE J;  3CCS H;  1YHQ H;  1YIT H;  1WKI A;  3CC7 H;  5MLC O;  3CF5 J;  2QA4 H;  4IOA J;  1YJN H;  1Q7Y J;  1M1K J;  5GAH N;  1YJ9 H;  1W2B H;  1K73 J;  3CC2 H;  1VQ7 H;  3CD6 H;  3PIO J;  3CCJ H;  2PA2 A;  5JVH J;  3CCV H;  1KD1 J;  1JJ2 H;  1Q81 J;  1VQ9 H;  3CCQ H;  1VQ8 H;  5H1S O;  1VQO H;  1YJW H;  1VQ5 H;  4IOC J;  3I55 H;  5GAD N;  2OTJ H;  1Q86 J;  3CCM H;  4U67 J;  2ZJP J;  1M90 J;  1Y69 K;  3CMA H;  1VQM H;  3CME H;  1QVG H;  1VQL H;  3CCR H;  4UY8 M;  4WFB J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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