3CCLH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3cclH00
4WFAJ 3G4SH 1K9MJ 1VQ9H 3CMEH 3DLLJ 2QEXH 4IO9J 1YJNH 1Q7YJ 2ZJRJ 1QVGH 5GADN 4IOAJ 3PIOJ 1VQ4H 4WFBJ 5JVGJ 2QA4H 1KD1J 3G6EH 3CCSH 3CD6H 1M90J 3CCQH 1VQ5H 1NJIJ 1VQ7H 3G71H 2OTLH 4UY8M 1JJ2H 1KQSH 5AN9F 4WF9J 2ZJQJ 1WKIA 3CCLH 4IOCJ 2PA2A 1YHQH 1VQLH 1M1KJ 1VQNH 1VQOH 1YI2H 3CCRH 1KC8J 5MLCO 1S72H 5DM7J 3CF5J 5GAHN 1VQMH 1W2BH 2OTJH 3CCUH 5GAGN 2ZJPJ 3CC7H 1QVFH 1VQ8H 1Q86J 3CPWH 3I55H 3OW2H 3J7ZM 1Y69K 1K73J 3CC4H 1YIJH 3CXCH 3CC2H 5H1SO 3CCJH 1YITH 5DM6J 1VQPH 3I56H 1YJWH 1VQ6H 4WCEJ 1VQKH 5GAEN 3CMAH 4WFNJ 1Q82J 5HL7J 5JVHJ 3PIPJ 3CCVH 1YJ9H 1Q81J 1K8AJ 3CCMH 3CCEH 4U67J 1N8RJ
chains in the Genus database with same CATH superfamily
4WFAJ 3NS1C 4USAA 3G4SH 1K9MJ 1VQ9H 3CMEH 3DLLJ 3WNZA 2QEXH 4IO9J 3NVYC 1YJNH 1Q7YJ 2ZJRJ 3C2EA 1BRWA 5AYYA 3NVZC 5MPOC 3AM9A 3TQVA 1QVGH 3C2VA 3WO0A 2Q5WE 5GADN 4IOAJ 3PIOJ 3FC4A 1RM6A 4C7ZA 1VQ4H 2W3SB 3NRZC 3GNNA 4WFBJ 4AP8A 5JVGJ 2QA4H 2I1OA 1QAPA 3FAHA 3G6EH 1KD1J 4C80A 3CCSH 3H5QA 3CD6H 1M90J 2OMDA 3CCQH 2B7QA 1VQ5H 3EUB4 1NJIJ 1VQ7H 3G71H 2OTLH 3C2OA 4UY8M 1JJ2H 1KQSH 4LHMA 2TPTA 5AN9F 5AYXA 5EP8A 4WF9J 2ZJQJ 1WKIA 5HULA 3CCLH 4IOCJ 1N5WB 1N61B 2JBMA 4X46A 2PA2A 1YHQH 1VQLH 1M1KJ 3C2RA 1VQNH 1VQOH 1YI2H 3CCRH 1DGJA 5EY3A 1N60B 4GA5A 1KC8J 1O4UA 2WP4A 3BIIE 5MLCO 1N62B 1S72H 1ZXIB 4GA4A 5DM7J 1YTKA 4YYYA 3CF5J 5GAHN 1FIQC 1VLBA 1VQMH 1W2BH 1QPRA 1FO4A 2J0FA 5AYZA 1JRPB 2OTJH 2DSJA 3CCUH 2WK6A 3B9JC 5GAGN 2ZJPJ 3CC7H 1SB3A 1QVFH 1VQ8H 3AMZA 2B7PA 1YTEA 2W55B 4US9A 1QPQA 4ZOHA 2I14A 5HUOA 4YEKA 1Q86J 1WYGA 3CPWH 3I55H 3C2FA 4C7YA 4KWVA 4KWWA 3OW2H 1X1OA 3RPFA 3J7ZM 1Y69K 4EAFA 3VMMA 1K73J 3CC4H 1FMAE 3PAJA 1YIJH 3NVVC 4US8A 3CXCH 2E3TA 3CC2H 1JROB 5H1SO 3CCJH 1FM0E 1UOUA 1YITH 1YTDA 3ETRC 1QPOA 5DM6J 1V97A 1VQPH 1N5XA 3I56H 1YJWH 1AZYA 1FFUB 1VQ6H 4WCEJ 1QPNA 1VQKH 1SIJA 3WO1A 4XR5A 5GAEN 2WK5A 4WFNJ 2B7NA 3CMAH 3L4PA 3SR6C 1Q82J 3NVWC 2W3RB 5HL7J 1NVJA 5JVHJ 4I9AA 4EADA 1OTPA 3PIPJ 3CCVH 1YJ9H 1Q81J 1VDVA 4GA6A 1K8AJ 1FFVB 1N63B 3CCMH 1NVIE 2W54B 3L0GA 3CCEH 5HUPA 4U67J 2QIEA 3AN1A 1N8RJ
chains in the Genus database with same CATH topology
4WFAJ 3G4SH 1K9MJ 1VQ9H 3CMEH 3DLLJ 2QEXH 4IO9J 1YJNH 1Q7YJ 2ZJRJ 1QVGH 5GADN 4IOAJ 3PIOJ 1VQ4H 4WFBJ 5JVGJ 2QA4H 1KD1J 3G6EH 3CCSH 3CD6H 1M90J 3CCQH 1VQ5H 1NJIJ 1VQ7H 3G71H 2OTLH 4UY8M 1JJ2H 1KQSH 5AN9F 4WF9J 2ZJQJ 1WKIA 3CCLH 4IOCJ 2PA2A 1YHQH 1VQLH 1M1KJ 1VQNH 1VQOH 1YI2H 3CCRH 1KC8J 5MLCO 1S72H 5DM7J 3CF5J 5GAHN 1VQMH 1W2BH 2OTJH 3CCUH 5GAGN 2ZJPJ 3CC7H 1QVFH 1VQ8H 1Q86J 3CPWH 3I55H 3OW2H 3J7ZM 1Y69K 1K73J 3CC4H 1YIJH 3CXCH 3CC2H 5H1SO 3CCJH 1YITH 5DM6J 1VQPH 3I56H 1YJWH 1VQ6H 4WCEJ 1VQKH 5GAEN 3CMAH 4WFNJ 1Q82J 5HL7J 5JVHJ 3PIPJ 3CCVH 1YJ9H 1Q81J 1K8AJ 3CCMH 3CCEH 4U67J 1N8RJ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFA J;  3G4S H;  1K9M J;  1VQ9 H;  3CME H;  3DLL J;  2QEX H;  4IO9 J;  1YJN H;  1Q7Y J;  2ZJR J;  1QVG H;  5GAD N;  4IOA J;  3PIO J;  1VQ4 H;  4WFB J;  5JVG J;  2QA4 H;  1KD1 J;  3G6E H;  3CCS H;  3CD6 H;  1M90 J;  3CCQ H;  1VQ5 H;  1NJI J;  1VQ7 H;  3G71 H;  2OTL H;  4UY8 M;  1JJ2 H;  1KQS H;  5AN9 F;  4WF9 J;  2ZJQ J;  1WKI A;  3CCL H;  4IOC J;  2PA2 A;  1YHQ H;  1VQL H;  1M1K J;  1VQN H;  1VQO H;  1YI2 H;  3CCR H;  1KC8 J;  5MLC O;  1S72 H;  5DM7 J;  3CF5 J;  5GAH N;  1VQM H;  1W2B H;  2OTJ H;  3CCU H;  5GAG N;  2ZJP J;  3CC7 H;  1QVF H;  1VQ8 H;  1Q86 J;  3CPW H;  3I55 H;  3OW2 H;  3J7Z M;  1Y69 K;  1K73 J;  3CC4 H;  1YIJ H;  3CXC H;  3CC2 H;  5H1S O;  3CCJ H;  1YIT H;  5DM6 J;  1VQP H;  3I56 H;  1YJW H;  1VQ6 H;  4WCE J;  1VQK H;  5GAE N;  3CMA H;  4WFN J;  1Q82 J;  5HL7 J;  5JVH J;  3PIP J;  3CCV H;  1YJ9 H;  1Q81 J;  1K8A J;  3CCM H;  3CCE H;  4U67 J;  1N8R J; 
#chains in the Genus database with same CATH topology
 4WFA J;  3NS1 C;  4USA A;  3G4S H;  1K9M J;  1VQ9 H;  3CME H;  3DLL J;  3WNZ A;  2QEX H;  4IO9 J;  3NVY C;  1YJN H;  1Q7Y J;  2ZJR J;  3C2E A;  1BRW A;  5AYY A;  3NVZ C;  5MPO C;  3AM9 A;  3TQV A;  1QVG H;  3C2V A;  3WO0 A;  2Q5W E;  5GAD N;  4IOA J;  3PIO J;  3FC4 A;  1RM6 A;  4C7Z A;  1VQ4 H;  2W3S B;  3NRZ C;  3GNN A;  4WFB J;  4AP8 A;  5JVG J;  2QA4 H;  2I1O A;  1QAP A;  3FAH A;  3G6E H;  1KD1 J;  4C80 A;  3CCS H;  3H5Q A;  3CD6 H;  1M90 J;  2OMD A;  3CCQ H;  2B7Q A;  1VQ5 H;  3EUB 4;  1NJI J;  1VQ7 H;  3G71 H;  2OTL H;  3C2O A;  4UY8 M;  1JJ2 H;  1KQS H;  4LHM A;  2TPT A;  5AN9 F;  5AYX A;  5EP8 A;  4WF9 J;  2ZJQ J;  1WKI A;  5HUL A;  3CCL H;  4IOC J;  1N5W B;  1N61 B;  2JBM A;  4X46 A;  2PA2 A;  1YHQ H;  1VQL H;  1M1K J;  3C2R A;  1VQN H;  1VQO H;  1YI2 H;  3CCR H;  1DGJ A;  5EY3 A;  1N60 B;  4GA5 A;  1KC8 J;  1O4U A;  2WP4 A;  3BII E;  5MLC O;  1N62 B;  1S72 H;  1ZXI B;  4GA4 A;  5DM7 J;  1YTK A;  4YYY A;  3CF5 J;  5GAH N;  1FIQ C;  1VLB A;  1VQM H;  1W2B H;  1QPR A;  1FO4 A;  2J0F A;  5AYZ A;  1JRP B;  2OTJ H;  2DSJ A;  3CCU H;  2WK6 A;  3B9J C;  5GAG N;  2ZJP J;  3CC7 H;  1SB3 A;  1QVF H;  1VQ8 H;  3AMZ A;  2B7P A;  1YTE A;  2W55 B;  4US9 A;  1QPQ A;  4ZOH A;  2I14 A;  5HUO A;  4YEK A;  1Q86 J;  1WYG A;  3CPW H;  3I55 H;  3C2F A;  4C7Y A;  4KWV A;  4KWW A;  3OW2 H;  1X1O A;  3RPF A;  3J7Z M;  1Y69 K;  4EAF A;  3VMM A;  1K73 J;  3CC4 H;  1FMA E;  3PAJ A;  1YIJ H;  3NVV C;  4US8 A;  3CXC H;  2E3T A;  3CC2 H;  1JRO B;  5H1S O;  3CCJ H;  1FM0 E;  1UOU A;  1YIT H;  1YTD A;  3ETR C;  1QPO A;  5DM6 J;  1V97 A;  1VQP H;  1N5X A;  3I56 H;  1YJW H;  1AZY A;  1FFU B;  1VQ6 H;  4WCE J;  1QPN A;  1VQK H;  1SIJ A;  3WO1 A;  4XR5 A;  5GAE N;  2WK5 A;  4WFN J;  2B7N A;  3CMA H;  3L4P A;  3SR6 C;  1Q82 J;  3NVW C;  2W3R B;  5HL7 J;  1NVJ A;  5JVH J;  4I9A A;  4EAD A;  1OTP A;  3PIP J;  3CCV H;  1YJ9 H;  1Q81 J;  1VDV A;  4GA6 A;  1K8A J;  1FFV B;  1N63 B;  3CCM H;  1NVI E;  2W54 B;  3L0G A;  3CCE H;  5HUP A;  4U67 J;  2QIE A;  3AN1 A;  1N8R J; 
#chains in the Genus database with same CATH homology
 4WFA J;  3G4S H;  1K9M J;  1VQ9 H;  3CME H;  3DLL J;  2QEX H;  4IO9 J;  1YJN H;  1Q7Y J;  2ZJR J;  1QVG H;  5GAD N;  4IOA J;  3PIO J;  1VQ4 H;  4WFB J;  5JVG J;  2QA4 H;  1KD1 J;  3G6E H;  3CCS H;  3CD6 H;  1M90 J;  3CCQ H;  1VQ5 H;  1NJI J;  1VQ7 H;  3G71 H;  2OTL H;  4UY8 M;  1JJ2 H;  1KQS H;  5AN9 F;  4WF9 J;  2ZJQ J;  1WKI A;  3CCL H;  4IOC J;  2PA2 A;  1YHQ H;  1VQL H;  1M1K J;  1VQN H;  1VQO H;  1YI2 H;  3CCR H;  1KC8 J;  5MLC O;  1S72 H;  5DM7 J;  3CF5 J;  5GAH N;  1VQM H;  1W2B H;  2OTJ H;  3CCU H;  5GAG N;  2ZJP J;  3CC7 H;  1QVF H;  1VQ8 H;  1Q86 J;  3CPW H;  3I55 H;  3OW2 H;  3J7Z M;  1Y69 K;  1K73 J;  3CC4 H;  1YIJ H;  3CXC H;  3CC2 H;  5H1S O;  3CCJ H;  1YIT H;  5DM6 J;  1VQP H;  3I56 H;  1YJW H;  1VQ6 H;  4WCE J;  1VQK H;  5GAE N;  3CMA H;  4WFN J;  1Q82 J;  5HL7 J;  5JVH J;  3PIP J;  3CCV H;  1YJ9 H;  1Q81 J;  1K8A J;  3CCM H;  3CCE H;  4U67 J;  1N8R J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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