3CCMH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3ccmH00
4WFAJ 3CCEH 5GAGN 3CF5J 1N8RJ 3CCLH 1VQOH 4WF9J 1JJ2H 1YJNH 1VQLH 1YHQH 1VQPH 1KQSH 4U67J 3CC7H 3J7ZM 2PA2A 3CCUH 3G6EH 5GADN 3G4SH 3CCSH 1VQ9H 5H1SO 4WFNJ 5HL7J 3PIPJ 3I56H 3CXCH 3CCMH 5GAEN 5AN9F 1YIJH 4IOAJ 3G71H 1Q82J 2ZJPJ 4IOCJ 1K9MJ 2QA4H 3CPWH 1KC8J 1WKIA 1VQ4H 1Q86J 5DM7J 5JVHJ 2OTLH 2ZJRJ 1VQ7H 3CD6H 1S72H 3CCRH 3CMAH 3OW2H 1K73J 1VQKH 1M1KJ 1K8AJ 5DM6J 5JVGJ 1QVGH 1Y69K 3CCQH 1Q7YJ 1VQ6H 3CC2H 2OTJH 4IO9J 5GAHN 1Q81J 5MLCO 1VQ8H 1VQNH 2ZJQJ 3CMEH 4WCEJ 4UY8M 3I55H 1YJ9H 1W2BH 1VQ5H 1NJIJ 1YI2H 4WFBJ 1KD1J 3DLLJ 3CCVH 1M90J 1QVFH 1YJWH 3CCJH 3CC4H 1YITH 3PIOJ 2QEXH 1VQMH
chains in the Genus database with same CATH superfamily
1QPQA 1SIJA 4WFAJ 3CCEH 1O4UA 2I1OA 3FAHA 5GAGN 2W3SB 2I14A 3CF5J 1QPOA 1X1OA 3CCLH 1N8RJ 2WK5A 1YTKA 1VQOH 4WF9J 1JJ2H 4C7ZA 1YJNH 1FFUB 3NS1C 1VQLH 4I9AA 1YHQH 4GA4A 1N63B 1QPRA 3C2OA 1VQPH 1KQSH 4U67J 1DGJA 3CC7H 3J7ZM 3C2RA 4US9A 2PA2A 1NVIE 3CCUH 3G6EH 3B9JC 4LHMA 1JROB 3EUB4 5GADN 3G4SH 3CCSH 1VQ9H 2W54B 2Q5WE 5HULA 5H1SO 1OTPA 3C2EA 4WFNJ 3L0GA 5HL7J 4GA6A 3PIPJ 1VDVA 1QPNA 5HUPA 4XR5A 3WO0A 1N5XA 5EP8A 4AP8A 5AYZA 4C80A 5MPOC 3I56H 3CXCH 4USAA 1FIQC 3CCMH 3NVWC 5GAEN 5AN9F 1YIJH 3FC4A 2DSJA 4ZOHA 4IOAJ 3G71H 2WP4A 1Q82J 3BIIE 1AZYA 1WYGA 2ZJPJ 4IOCJ 1FO4A 1K9MJ 2QA4H 2WK6A 3CPWH 3NVZC 1KC8J 1YTDA 4KWVA 1BRWA 3C2VA 3SR6C 1WKIA 1QAPA 1VQ4H 1Q86J 2JBMA 5DM7J 5JVHJ 2OTLH 2ZJRJ 2OMDA 1N60B 4X46A 2J0FA 1VQ7H 3NVYC 4YYYA 3CD6H 1S72H 2W3RB 4EAFA 2QIEA 3CCRH 3CMAH 3ETRC 5HUOA 4EADA 3OW2H 5EY3A 1UOUA 1YTEA 1K73J 1VQKH 1M1KJ 3AN1A 1K8AJ 1NVJA 5DM6J 3AM9A 2B7PA 3TQVA 5JVGJ 3PAJA 1V97A 1QVGH 4KWWA 3WO1A 1Y69K 2B7QA 2B7NA 4US8A 3CCQH 1Q7YJ 3CC2H 1VQ6H 2OTJH 4IO9J 1SB3A 1VLBA 5GAHN 1ZXIB 1RM6A 3VMMA 1Q81J 5MLCO 1VQ8H 1VQNH 2ZJQJ 3CMEH 4WCEJ 4UY8M 3I55H 1YJ9H 1W2BH 1VQ5H 1NJIJ 1YI2H 3RPFA 4WFBJ 5AYYA 2TPTA 1JRPB 1KD1J 3DLLJ 1N5WB 1N61B 3C2FA 3AMZA 3H5QA 3NVVC 4C7YA 1FMAE 3L4PA 3CCVH 1M90J 3NRZC 1QVFH 4GA5A 3WNZA 2E3TA 5AYXA 4YEKA 1YJWH 3CCJH 3CC4H 1YITH 3PIOJ 1FM0E 2QEXH 1FFVB 1VQMH 1N62B 3GNNA 2W55B
chains in the Genus database with same CATH topology
4WFAJ 3CCEH 5GAGN 3CF5J 1N8RJ 3CCLH 1VQOH 4WF9J 1JJ2H 1YJNH 1VQLH 1YHQH 1VQPH 1KQSH 4U67J 3CC7H 3J7ZM 2PA2A 3CCUH 3G6EH 5GADN 3G4SH 3CCSH 1VQ9H 5H1SO 4WFNJ 5HL7J 3PIPJ 3I56H 3CXCH 3CCMH 5GAEN 5AN9F 1YIJH 4IOAJ 3G71H 1Q82J 2ZJPJ 4IOCJ 1K9MJ 2QA4H 3CPWH 1KC8J 1WKIA 1VQ4H 1Q86J 5DM7J 5JVHJ 2OTLH 2ZJRJ 1VQ7H 3CD6H 1S72H 3CCRH 3CMAH 3OW2H 1K73J 1VQKH 1M1KJ 1K8AJ 5DM6J 5JVGJ 1QVGH 1Y69K 3CCQH 1Q7YJ 1VQ6H 3CC2H 2OTJH 4IO9J 5GAHN 1Q81J 5MLCO 1VQ8H 1VQNH 2ZJQJ 3CMEH 4WCEJ 4UY8M 3I55H 1YJ9H 1W2BH 1VQ5H 1NJIJ 1YI2H 4WFBJ 1KD1J 3DLLJ 3CCVH 1M90J 1QVFH 1YJWH 3CCJH 3CC4H 1YITH 3PIOJ 2QEXH 1VQMH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFA J;  3CCE H;  5GAG N;  3CF5 J;  1N8R J;  3CCL H;  1VQO H;  4WF9 J;  1JJ2 H;  1YJN H;  1VQL H;  1YHQ H;  1VQP H;  1KQS H;  4U67 J;  3CC7 H;  3J7Z M;  2PA2 A;  3CCU H;  3G6E H;  5GAD N;  3G4S H;  3CCS H;  1VQ9 H;  5H1S O;  4WFN J;  5HL7 J;  3PIP J;  3I56 H;  3CXC H;  3CCM H;  5GAE N;  5AN9 F;  1YIJ H;  4IOA J;  3G71 H;  1Q82 J;  2ZJP J;  4IOC J;  1K9M J;  2QA4 H;  3CPW H;  1KC8 J;  1WKI A;  1VQ4 H;  1Q86 J;  5DM7 J;  5JVH J;  2OTL H;  2ZJR J;  1VQ7 H;  3CD6 H;  1S72 H;  3CCR H;  3CMA H;  3OW2 H;  1K73 J;  1VQK H;  1M1K J;  1K8A J;  5DM6 J;  5JVG J;  1QVG H;  1Y69 K;  3CCQ H;  1Q7Y J;  1VQ6 H;  3CC2 H;  2OTJ H;  4IO9 J;  5GAH N;  1Q81 J;  5MLC O;  1VQ8 H;  1VQN H;  2ZJQ J;  3CME H;  4WCE J;  4UY8 M;  3I55 H;  1YJ9 H;  1W2B H;  1VQ5 H;  1NJI J;  1YI2 H;  4WFB J;  1KD1 J;  3DLL J;  3CCV H;  1M90 J;  1QVF H;  1YJW H;  3CCJ H;  3CC4 H;  1YIT H;  3PIO J;  2QEX H;  1VQM H; 
#chains in the Genus database with same CATH topology
 1QPQ A;  1SIJ A;  4WFA J;  3CCE H;  1O4U A;  2I1O A;  3FAH A;  5GAG N;  2W3S B;  2I14 A;  3CF5 J;  1QPO A;  1X1O A;  3CCL H;  1N8R J;  2WK5 A;  1YTK A;  1VQO H;  4WF9 J;  1JJ2 H;  4C7Z A;  1YJN H;  1FFU B;  3NS1 C;  1VQL H;  4I9A A;  1YHQ H;  4GA4 A;  1N63 B;  1QPR A;  3C2O A;  1VQP H;  1KQS H;  4U67 J;  1DGJ A;  3CC7 H;  3J7Z M;  3C2R A;  4US9 A;  2PA2 A;  1NVI E;  3CCU H;  3G6E H;  3B9J C;  4LHM A;  1JRO B;  3EUB 4;  5GAD N;  3G4S H;  3CCS H;  1VQ9 H;  2W54 B;  2Q5W E;  5HUL A;  5H1S O;  1OTP A;  3C2E A;  4WFN J;  3L0G A;  5HL7 J;  4GA6 A;  3PIP J;  1VDV A;  1QPN A;  5HUP A;  4XR5 A;  3WO0 A;  1N5X A;  5EP8 A;  4AP8 A;  5AYZ A;  4C80 A;  5MPO C;  3I56 H;  3CXC H;  4USA A;  1FIQ C;  3CCM H;  3NVW C;  5GAE N;  5AN9 F;  1YIJ H;  3FC4 A;  2DSJ A;  4ZOH A;  4IOA J;  3G71 H;  2WP4 A;  1Q82 J;  3BII E;  1AZY A;  1WYG A;  2ZJP J;  4IOC J;  1FO4 A;  1K9M J;  2QA4 H;  2WK6 A;  3CPW H;  3NVZ C;  1KC8 J;  1YTD A;  4KWV A;  1BRW A;  3C2V A;  3SR6 C;  1WKI A;  1QAP A;  1VQ4 H;  1Q86 J;  2JBM A;  5DM7 J;  5JVH J;  2OTL H;  2ZJR J;  2OMD A;  1N60 B;  4X46 A;  2J0F A;  1VQ7 H;  3NVY C;  4YYY A;  3CD6 H;  1S72 H;  2W3R B;  4EAF A;  2QIE A;  3CCR H;  3CMA H;  3ETR C;  5HUO A;  4EAD A;  3OW2 H;  5EY3 A;  1UOU A;  1YTE A;  1K73 J;  1VQK H;  1M1K J;  3AN1 A;  1K8A J;  1NVJ A;  5DM6 J;  3AM9 A;  2B7P A;  3TQV A;  5JVG J;  3PAJ A;  1V97 A;  1QVG H;  4KWW A;  3WO1 A;  1Y69 K;  2B7Q A;  2B7N A;  4US8 A;  3CCQ H;  1Q7Y J;  3CC2 H;  1VQ6 H;  2OTJ H;  4IO9 J;  1SB3 A;  1VLB A;  5GAH N;  1ZXI B;  1RM6 A;  3VMM A;  1Q81 J;  5MLC O;  1VQ8 H;  1VQN H;  2ZJQ J;  3CME H;  4WCE J;  4UY8 M;  3I55 H;  1YJ9 H;  1W2B H;  1VQ5 H;  1NJI J;  1YI2 H;  3RPF A;  4WFB J;  5AYY A;  2TPT A;  1JRP B;  1KD1 J;  3DLL J;  1N5W B;  1N61 B;  3C2F A;  3AMZ A;  3H5Q A;  3NVV C;  4C7Y A;  1FMA E;  3L4P A;  3CCV H;  1M90 J;  3NRZ C;  1QVF H;  4GA5 A;  3WNZ A;  2E3T A;  5AYX A;  4YEK A;  1YJW H;  3CCJ H;  3CC4 H;  1YIT H;  3PIO J;  1FM0 E;  2QEX H;  1FFV B;  1VQM H;  1N62 B;  3GNN A;  2W55 B; 
#chains in the Genus database with same CATH homology
 4WFA J;  3CCE H;  5GAG N;  3CF5 J;  1N8R J;  3CCL H;  1VQO H;  4WF9 J;  1JJ2 H;  1YJN H;  1VQL H;  1YHQ H;  1VQP H;  1KQS H;  4U67 J;  3CC7 H;  3J7Z M;  2PA2 A;  3CCU H;  3G6E H;  5GAD N;  3G4S H;  3CCS H;  1VQ9 H;  5H1S O;  4WFN J;  5HL7 J;  3PIP J;  3I56 H;  3CXC H;  3CCM H;  5GAE N;  5AN9 F;  1YIJ H;  4IOA J;  3G71 H;  1Q82 J;  2ZJP J;  4IOC J;  1K9M J;  2QA4 H;  3CPW H;  1KC8 J;  1WKI A;  1VQ4 H;  1Q86 J;  5DM7 J;  5JVH J;  2OTL H;  2ZJR J;  1VQ7 H;  3CD6 H;  1S72 H;  3CCR H;  3CMA H;  3OW2 H;  1K73 J;  1VQK H;  1M1K J;  1K8A J;  5DM6 J;  5JVG J;  1QVG H;  1Y69 K;  3CCQ H;  1Q7Y J;  1VQ6 H;  3CC2 H;  2OTJ H;  4IO9 J;  5GAH N;  1Q81 J;  5MLC O;  1VQ8 H;  1VQN H;  2ZJQ J;  3CME H;  4WCE J;  4UY8 M;  3I55 H;  1YJ9 H;  1W2B H;  1VQ5 H;  1NJI J;  1YI2 H;  4WFB J;  1KD1 J;  3DLL J;  3CCV H;  1M90 J;  1QVF H;  1YJW H;  3CCJ H;  3CC4 H;  1YIT H;  3PIO J;  2QEX H;  1VQM H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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