3CCRH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3ccrH00
1VQ5H 1QVGH 3CCUH 1N8RJ 3CF5J 1KC8J 1QVFH 2PA2A 5DM7J 3CC2H 1VQNH 3CCMH 1YI2H 1Q86J 3CCSH 4UY8M 4IOAJ 2QA4H 1KQSH 5H1SO 3OW2H 2ZJPJ 3CXCH 2OTLH 1VQ8H 3CCVH 1YIJH 5JVHJ 1M1KJ 1VQMH 5DM6J 2OTJH 1VQOH 4U67J 1YITH 3I55H 4WFNJ 3G71H 3CCRH 4IO9J 1NJIJ 1VQ4H 1W2BH 3CMEH 3PIOJ 3CC4H 1VQPH 1YJ9H 1Q81J 3CC7H 4WCEJ 3CCJH 2ZJRJ 1WKIA 5JVGJ 5GAEN 3CMAH 1Y69K 1K73J 1VQKH 1YJWH 3CPWH 1K8AJ 1VQ9H 3CCQH 3DLLJ 1K9MJ 2ZJQJ 3J7ZM 3CCEH 4IOCJ 1Q7YJ 3G6EH 1M90J 4WFAJ 3CCLH 1JJ2H 1VQ6H 2QEXH 5GADN 5AN9F 5MLCO 1YHQH 1VQ7H 5GAGN 4WFBJ 4WF9J 5HL7J 1Q82J 3PIPJ 5GAHN 3CD6H 3I56H 1VQLH 3G4SH 1YJNH 1KD1J 1S72H
chains in the Genus database with same CATH superfamily
4C7YA 3C2EA 3AM9A 1VQ5H 1QVGH 3CCUH 1FFUB 1OTPA 1N8RJ 5MPOC 3CF5J 1KC8J 1QVFH 1RM6A 5HUPA 3WO1A 5EY3A 3C2OA 1V97A 2PA2A 1N62B 5DM7J 3FAHA 4X46A 4EADA 3CC2H 2I14A 1VQNH 2B7NA 4GA6A 3CCMH 4EAFA 1YI2H 1Q86J 3CCSH 4UY8M 1FO4A 2WK6A 4IOAJ 2QA4H 3L0GA 3TQVA 1KQSH 3NRZC 4C80A 2TPTA 1AZYA 3SR6C 5H1SO 3OW2H 2ZJPJ 3CXCH 1O4UA 2OTLH 3NVWC 3WO0A 1VQ8H 1FIQC 3CCVH 4USAA 4GA5A 1YIJH 2OMDA 5JVHJ 1BRWA 2W55B 1FM0E 1M1KJ 5EP8A 1QPOA 4C7ZA 1N61B 1DGJA 5DM6J 1VQMH 2OTJH 1VDVA 1WYGA 1VQOH 4U67J 1YITH 3I55H 1YTDA 3NVZC 1NVJA 4WFNJ 3GNNA 3AN1A 2W3RB 4LHMA 3WNZA 3G71H 3CCRH 4IO9J 1NJIJ 1VQ4H 1W2BH 3CMEH 3PIOJ 3EUB4 3CC4H 1NVIE 1VQPH 2DSJA 1FMAE 1YJ9H 2WP4A 1YTEA 3AMZA 3NVYC 1Q81J 1QPRA 3C2VA 1ZXIB 3CC7H 4WCEJ 3CCJH 2ZJRJ 1WKIA 5JVGJ 1N5WB 1QPNA 2W3SB 5HULA 5GAEN 5AYZA 3CMAH 2QIEA 3L4PA 5HUOA 3RPFA 1Y69K 1K73J 1VQKH 5AYXA 2W54B 3C2FA 3VMMA 1YJWH 1X1OA 5AYYA 3CPWH 2JBMA 4KWWA 1K8AJ 2WK5A 4ZOHA 4XR5A 1VQ9H 3CCQH 1SIJA 1VLBA 3DLLJ 4YYYA 1K9MJ 3PAJA 2ZJQJ 3J7ZM 1SB3A 3CCEH 3ETRC 3B9JC 4IOCJ 4US9A 2E3TA 1Q7YJ 3NVVC 1N60B 2Q5WE 3G6EH 1M90J 4WFAJ 3CCLH 1JJ2H 2I1OA 1VQ6H 4KWVA 4US8A 2QEXH 1QPQA 2J0FA 1N63B 5GADN 5AN9F 5MLCO 4AP8A 1YHQH 1VQ7H 1FFVB 4I9AA 5GAGN 4YEKA 1JROB 3H5QA 4WFBJ 5HL7J 1N5XA 1UOUA 4WF9J 1Q82J 3PIPJ 3C2RA 4GA4A 3FC4A 5GAHN 3CD6H 3NS1C 3BIIE 2B7QA 3I56H 1YTKA 1VQLH 1QAPA 1JRPB 3G4SH 2B7PA 1YJNH 1KD1J 1S72H
chains in the Genus database with same CATH topology
1VQ5H 1QVGH 3CCUH 1N8RJ 3CF5J 1KC8J 1QVFH 2PA2A 5DM7J 3CC2H 1VQNH 3CCMH 1YI2H 1Q86J 3CCSH 4UY8M 4IOAJ 2QA4H 1KQSH 5H1SO 3OW2H 2ZJPJ 3CXCH 2OTLH 1VQ8H 3CCVH 1YIJH 5JVHJ 1M1KJ 1VQMH 5DM6J 2OTJH 1VQOH 4U67J 1YITH 3I55H 4WFNJ 3G71H 3CCRH 4IO9J 1NJIJ 1VQ4H 1W2BH 3CMEH 3PIOJ 3CC4H 1VQPH 1YJ9H 1Q81J 3CC7H 4WCEJ 3CCJH 2ZJRJ 1WKIA 5JVGJ 5GAEN 3CMAH 1Y69K 1K73J 1VQKH 1YJWH 3CPWH 1K8AJ 1VQ9H 3CCQH 3DLLJ 1K9MJ 2ZJQJ 3J7ZM 3CCEH 4IOCJ 1Q7YJ 3G6EH 1M90J 4WFAJ 3CCLH 1JJ2H 1VQ6H 2QEXH 5GADN 5AN9F 5MLCO 1YHQH 1VQ7H 5GAGN 4WFBJ 4WF9J 5HL7J 1Q82J 3PIPJ 5GAHN 3CD6H 3I56H 1VQLH 3G4SH 1YJNH 1KD1J 1S72H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ5 H;  1QVG H;  3CCU H;  1N8R J;  3CF5 J;  1KC8 J;  1QVF H;  2PA2 A;  5DM7 J;  3CC2 H;  1VQN H;  3CCM H;  1YI2 H;  1Q86 J;  3CCS H;  4UY8 M;  4IOA J;  2QA4 H;  1KQS H;  5H1S O;  3OW2 H;  2ZJP J;  3CXC H;  2OTL H;  1VQ8 H;  3CCV H;  1YIJ H;  5JVH J;  1M1K J;  1VQM H;  5DM6 J;  2OTJ H;  1VQO H;  4U67 J;  1YIT H;  3I55 H;  4WFN J;  3G71 H;  3CCR H;  4IO9 J;  1NJI J;  1VQ4 H;  1W2B H;  3CME H;  3PIO J;  3CC4 H;  1VQP H;  1YJ9 H;  1Q81 J;  3CC7 H;  4WCE J;  3CCJ H;  2ZJR J;  1WKI A;  5JVG J;  5GAE N;  3CMA H;  1Y69 K;  1K73 J;  1VQK H;  1YJW H;  3CPW H;  1K8A J;  1VQ9 H;  3CCQ H;  3DLL J;  1K9M J;  2ZJQ J;  3J7Z M;  3CCE H;  4IOC J;  1Q7Y J;  3G6E H;  1M90 J;  4WFA J;  3CCL H;  1JJ2 H;  1VQ6 H;  2QEX H;  5GAD N;  5AN9 F;  5MLC O;  1YHQ H;  1VQ7 H;  5GAG N;  4WFB J;  4WF9 J;  5HL7 J;  1Q82 J;  3PIP J;  5GAH N;  3CD6 H;  3I56 H;  1VQL H;  3G4S H;  1YJN H;  1KD1 J;  1S72 H; 
#chains in the Genus database with same CATH topology
 4C7Y A;  3C2E A;  3AM9 A;  1VQ5 H;  1QVG H;  3CCU H;  1FFU B;  1OTP A;  1N8R J;  5MPO C;  3CF5 J;  1KC8 J;  1QVF H;  1RM6 A;  5HUP A;  3WO1 A;  5EY3 A;  3C2O A;  1V97 A;  2PA2 A;  1N62 B;  5DM7 J;  3FAH A;  4X46 A;  4EAD A;  3CC2 H;  2I14 A;  1VQN H;  2B7N A;  4GA6 A;  3CCM H;  4EAF A;  1YI2 H;  1Q86 J;  3CCS H;  4UY8 M;  1FO4 A;  2WK6 A;  4IOA J;  2QA4 H;  3L0G A;  3TQV A;  1KQS H;  3NRZ C;  4C80 A;  2TPT A;  1AZY A;  3SR6 C;  5H1S O;  3OW2 H;  2ZJP J;  3CXC H;  1O4U A;  2OTL H;  3NVW C;  3WO0 A;  1VQ8 H;  1FIQ C;  3CCV H;  4USA A;  4GA5 A;  1YIJ H;  2OMD A;  5JVH J;  1BRW A;  2W55 B;  1FM0 E;  1M1K J;  5EP8 A;  1QPO A;  4C7Z A;  1N61 B;  1DGJ A;  5DM6 J;  1VQM H;  2OTJ H;  1VDV A;  1WYG A;  1VQO H;  4U67 J;  1YIT H;  3I55 H;  1YTD A;  3NVZ C;  1NVJ A;  4WFN J;  3GNN A;  3AN1 A;  2W3R B;  4LHM A;  3WNZ A;  3G71 H;  3CCR H;  4IO9 J;  1NJI J;  1VQ4 H;  1W2B H;  3CME H;  3PIO J;  3EUB 4;  3CC4 H;  1NVI E;  1VQP H;  2DSJ A;  1FMA E;  1YJ9 H;  2WP4 A;  1YTE A;  3AMZ A;  3NVY C;  1Q81 J;  1QPR A;  3C2V A;  1ZXI B;  3CC7 H;  4WCE J;  3CCJ H;  2ZJR J;  1WKI A;  5JVG J;  1N5W B;  1QPN A;  2W3S B;  5HUL A;  5GAE N;  5AYZ A;  3CMA H;  2QIE A;  3L4P A;  5HUO A;  3RPF A;  1Y69 K;  1K73 J;  1VQK H;  5AYX A;  2W54 B;  3C2F A;  3VMM A;  1YJW H;  1X1O A;  5AYY A;  3CPW H;  2JBM A;  4KWW A;  1K8A J;  2WK5 A;  4ZOH A;  4XR5 A;  1VQ9 H;  3CCQ H;  1SIJ A;  1VLB A;  3DLL J;  4YYY A;  1K9M J;  3PAJ A;  2ZJQ J;  3J7Z M;  1SB3 A;  3CCE H;  3ETR C;  3B9J C;  4IOC J;  4US9 A;  2E3T A;  1Q7Y J;  3NVV C;  1N60 B;  2Q5W E;  3G6E H;  1M90 J;  4WFA J;  3CCL H;  1JJ2 H;  2I1O A;  1VQ6 H;  4KWV A;  4US8 A;  2QEX H;  1QPQ A;  2J0F A;  1N63 B;  5GAD N;  5AN9 F;  5MLC O;  4AP8 A;  1YHQ H;  1VQ7 H;  1FFV B;  4I9A A;  5GAG N;  4YEK A;  1JRO B;  3H5Q A;  4WFB J;  5HL7 J;  1N5X A;  1UOU A;  4WF9 J;  1Q82 J;  3PIP J;  3C2R A;  4GA4 A;  3FC4 A;  5GAH N;  3CD6 H;  3NS1 C;  3BII E;  2B7Q A;  3I56 H;  1YTK A;  1VQL H;  1QAP A;  1JRP B;  3G4S H;  2B7P A;  1YJN H;  1KD1 J;  1S72 H; 
#chains in the Genus database with same CATH homology
 1VQ5 H;  1QVG H;  3CCU H;  1N8R J;  3CF5 J;  1KC8 J;  1QVF H;  2PA2 A;  5DM7 J;  3CC2 H;  1VQN H;  3CCM H;  1YI2 H;  1Q86 J;  3CCS H;  4UY8 M;  4IOA J;  2QA4 H;  1KQS H;  5H1S O;  3OW2 H;  2ZJP J;  3CXC H;  2OTL H;  1VQ8 H;  3CCV H;  1YIJ H;  5JVH J;  1M1K J;  1VQM H;  5DM6 J;  2OTJ H;  1VQO H;  4U67 J;  1YIT H;  3I55 H;  4WFN J;  3G71 H;  3CCR H;  4IO9 J;  1NJI J;  1VQ4 H;  1W2B H;  3CME H;  3PIO J;  3CC4 H;  1VQP H;  1YJ9 H;  1Q81 J;  3CC7 H;  4WCE J;  3CCJ H;  2ZJR J;  1WKI A;  5JVG J;  5GAE N;  3CMA H;  1Y69 K;  1K73 J;  1VQK H;  1YJW H;  3CPW H;  1K8A J;  1VQ9 H;  3CCQ H;  3DLL J;  1K9M J;  2ZJQ J;  3J7Z M;  3CCE H;  4IOC J;  1Q7Y J;  3G6E H;  1M90 J;  4WFA J;  3CCL H;  1JJ2 H;  1VQ6 H;  2QEX H;  5GAD N;  5AN9 F;  5MLC O;  1YHQ H;  1VQ7 H;  5GAG N;  4WFB J;  4WF9 J;  5HL7 J;  1Q82 J;  3PIP J;  5GAH N;  3CD6 H;  3I56 H;  1VQL H;  3G4S H;  1YJN H;  1KD1 J;  1S72 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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