3CCSH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3ccsH00
1YJWH 1Q81J 4WFNJ 1VQKH 3CCMH 1N8RJ 1WKIA 4IOCJ 5DM6J 1VQMH 1VQ5H 3DLLJ 1K8AJ 1KQSH 5GAHN 2ZJRJ 1JJ2H 5GAGN 1YITH 3CCQH 1K73J 1YIJH 1Q82J 1VQLH 1VQOH 1VQ7H 1QVGH 2OTLH 3CMAH 3CCJH 3CCSH 3CC4H 3CF5J 1KC8J 5DM7J 3G6EH 1VQ6H 3CCEH 1VQ8H 4U67J 3CCUH 1KD1J 1QVFH 3CPWH 1YHQH 2ZJQJ 1NJIJ 3I55H 1W2BH 3PIPJ 1YJ9H 1VQPH 3CD6H 1Y69K 3CC7H 1Q7YJ 3J7ZM 4IOAJ 3CCLH 3I56H 3CMEH 5AN9F 5HL7J 2QA4H 2QEXH 4UY8M 2OTJH 1VQ9H 3CCVH 5GAEN 1VQ4H 1VQNH 1Q86J 3CCRH 3CC2H 5JVHJ 1S72H 3OW2H 3CXCH 3G71H 5MLCO 1K9MJ 4WF9J 4WFBJ 2PA2A 1YJNH 3PIOJ 4WFAJ 5H1SO 3G4SH 5GADN 1YI2H 2ZJPJ 4WCEJ 5JVGJ 1M90J 1M1KJ 4IO9J
chains in the Genus database with same CATH superfamily
2W54B 1YJWH 1FFUB 4YEKA 1FIQC 4EADA 1Q81J 4WFNJ 3FAHA 1VQKH 3CCMH 1N8RJ 3C2EA 1WKIA 1AZYA 4IOCJ 3NRZC 5DM6J 1VQMH 1VQ5H 3DLLJ 1K8AJ 2DSJA 3NVZC 4GA4A 1KQSH 5HUPA 5GAHN 1DGJA 2ZJRJ 1JJ2H 4GA6A 1YTKA 5GAGN 1YITH 1N63B 3CCQH 1K73J 3AN1A 1YIJH 1Q82J 3WO1A 4XR5A 1NVJA 5AYXA 1VQOH 1QVGH 1VQ7H 1VQLH 2OTLH 4USAA 1N62B 2TPTA 3CMAH 3CCJH 3CCSH 1N61B 1QPQA 2B7PA 3CC4H 3CF5J 4YYYA 1KC8J 4C7ZA 5DM7J 3G6EH 1VQ6H 3AM9A 3CCEH 1VQ8H 1JRPB 3PAJA 4IO9J 4U67J 1VLBA 3CCUH 1QAPA 4US9A 4GA5A 3SR6C 1VDVA 1UOUA 1KD1J 3FC4A 4KWVA 1QVFH 1BRWA 1QPOA 3GNNA 3CPWH 3C2VA 3AMZA 1YHQH 1N5WB 1FMAE 2ZJQJ 3H5QA 5HUOA 1NJIJ 3I55H 2J0FA 1W2BH 3C2RA 3VMMA 1QPNA 4US8A 3PIPJ 1VQPH 1YJ9H 3CD6H 4C7YA 1ZXIB 3C2FA 1SB3A 1Y69K 3CC7H 1Q7YJ 3J7ZM 4IOAJ 3L0GA 3CCLH 3I56H 3CMEH 2WK5A 5AN9F 5AYZA 2I1OA 5HL7J 2QA4H 1OTPA 1N60B 3NVVC 5MPOC 1X1OA 2QEXH 4UY8M 2W3RB 4KWWA 2WP4A 2OTJH 1VQ9H 3CCVH 5GAEN 1V97A 1VQ4H 1VQNH 1Q86J 3B9JC 3CCRH 2B7QA 4AP8A 2JBMA 3EUB4 1FFVB 4EAFA 3ETRC 3CC2H 1FM0E 5JVHJ 4LHMA 3NS1C 3RPFA 3WNZA 2OMDA 1S72H 3OW2H 2I14A 3CXCH 1RM6A 1NVIE 3NVYC 5EP8A 3TQVA 2WK6A 2W3SB 5MLCO 3G71H 1N5XA 2B7NA 5HULA 1QPRA 3BIIE 2Q5WE 3WO0A 1K9MJ 1YTEA 1WYGA 5EY3A 4WF9J 3NVWC 5AYYA 4WFBJ 2PA2A 2QIEA 1FO4A 1YJNH 3PIOJ 2W55B 1SIJA 4ZOHA 4I9AA 4WFAJ 1YTDA 5H1SO 3G4SH 5GADN 3L4PA 1YI2H 2ZJPJ 2E3TA 4WCEJ 1JROB 5JVGJ 1M90J 4C80A 4X46A 3C2OA 1M1KJ 1O4UA
chains in the Genus database with same CATH topology
1YJWH 1Q81J 4WFNJ 1VQKH 3CCMH 1N8RJ 1WKIA 4IOCJ 5DM6J 1VQMH 1VQ5H 3DLLJ 1K8AJ 1KQSH 5GAHN 2ZJRJ 1JJ2H 5GAGN 1YITH 3CCQH 1K73J 1YIJH 1Q82J 1VQLH 1VQOH 1VQ7H 1QVGH 2OTLH 3CMAH 3CCJH 3CCSH 3CC4H 3CF5J 1KC8J 5DM7J 3G6EH 1VQ6H 3CCEH 1VQ8H 4U67J 3CCUH 1KD1J 1QVFH 3CPWH 1YHQH 2ZJQJ 1NJIJ 3I55H 1W2BH 3PIPJ 1YJ9H 1VQPH 3CD6H 1Y69K 3CC7H 1Q7YJ 3J7ZM 4IOAJ 3CCLH 3I56H 3CMEH 5AN9F 5HL7J 2QA4H 2QEXH 4UY8M 2OTJH 1VQ9H 3CCVH 5GAEN 1VQ4H 1VQNH 1Q86J 3CCRH 3CC2H 5JVHJ 1S72H 3OW2H 3CXCH 3G71H 5MLCO 1K9MJ 4WF9J 4WFBJ 2PA2A 1YJNH 3PIOJ 4WFAJ 5H1SO 3G4SH 5GADN 1YI2H 2ZJPJ 4WCEJ 5JVGJ 1M90J 1M1KJ 4IO9J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJW H;  1Q81 J;  4WFN J;  1VQK H;  3CCM H;  1N8R J;  1WKI A;  4IOC J;  5DM6 J;  1VQM H;  1VQ5 H;  3DLL J;  1K8A J;  1KQS H;  5GAH N;  2ZJR J;  1JJ2 H;  5GAG N;  1YIT H;  3CCQ H;  1K73 J;  1YIJ H;  1Q82 J;  1VQL H;  1VQO H;  1VQ7 H;  1QVG H;  2OTL H;  3CMA H;  3CCJ H;  3CCS H;  3CC4 H;  3CF5 J;  1KC8 J;  5DM7 J;  3G6E H;  1VQ6 H;  3CCE H;  1VQ8 H;  4U67 J;  3CCU H;  1KD1 J;  1QVF H;  3CPW H;  1YHQ H;  2ZJQ J;  1NJI J;  3I55 H;  1W2B H;  3PIP J;  1YJ9 H;  1VQP H;  3CD6 H;  1Y69 K;  3CC7 H;  1Q7Y J;  3J7Z M;  4IOA J;  3CCL H;  3I56 H;  3CME H;  5AN9 F;  5HL7 J;  2QA4 H;  2QEX H;  4UY8 M;  2OTJ H;  1VQ9 H;  3CCV H;  5GAE N;  1VQ4 H;  1VQN H;  1Q86 J;  3CCR H;  3CC2 H;  5JVH J;  1S72 H;  3OW2 H;  3CXC H;  3G71 H;  5MLC O;  1K9M J;  4WF9 J;  4WFB J;  2PA2 A;  1YJN H;  3PIO J;  4WFA J;  5H1S O;  3G4S H;  5GAD N;  1YI2 H;  2ZJP J;  4WCE J;  5JVG J;  1M90 J;  1M1K J;  4IO9 J; 
#chains in the Genus database with same CATH topology
 2W54 B;  1YJW H;  1FFU B;  4YEK A;  1FIQ C;  4EAD A;  1Q81 J;  4WFN J;  3FAH A;  1VQK H;  3CCM H;  1N8R J;  3C2E A;  1WKI A;  1AZY A;  4IOC J;  3NRZ C;  5DM6 J;  1VQM H;  1VQ5 H;  3DLL J;  1K8A J;  2DSJ A;  3NVZ C;  4GA4 A;  1KQS H;  5HUP A;  5GAH N;  1DGJ A;  2ZJR J;  1JJ2 H;  4GA6 A;  1YTK A;  5GAG N;  1YIT H;  1N63 B;  3CCQ H;  1K73 J;  3AN1 A;  1YIJ H;  1Q82 J;  3WO1 A;  4XR5 A;  1NVJ A;  5AYX A;  1VQO H;  1QVG H;  1VQ7 H;  1VQL H;  2OTL H;  4USA A;  1N62 B;  2TPT A;  3CMA H;  3CCJ H;  3CCS H;  1N61 B;  1QPQ A;  2B7P A;  3CC4 H;  3CF5 J;  4YYY A;  1KC8 J;  4C7Z A;  5DM7 J;  3G6E H;  1VQ6 H;  3AM9 A;  3CCE H;  1VQ8 H;  1JRP B;  3PAJ A;  4IO9 J;  4U67 J;  1VLB A;  3CCU H;  1QAP A;  4US9 A;  4GA5 A;  3SR6 C;  1VDV A;  1UOU A;  1KD1 J;  3FC4 A;  4KWV A;  1QVF H;  1BRW A;  1QPO A;  3GNN A;  3CPW H;  3C2V A;  3AMZ A;  1YHQ H;  1N5W B;  1FMA E;  2ZJQ J;  3H5Q A;  5HUO A;  1NJI J;  3I55 H;  2J0F A;  1W2B H;  3C2R A;  3VMM A;  1QPN A;  4US8 A;  3PIP J;  1VQP H;  1YJ9 H;  3CD6 H;  4C7Y A;  1ZXI B;  3C2F A;  1SB3 A;  1Y69 K;  3CC7 H;  1Q7Y J;  3J7Z M;  4IOA J;  3L0G A;  3CCL H;  3I56 H;  3CME H;  2WK5 A;  5AN9 F;  5AYZ A;  2I1O A;  5HL7 J;  2QA4 H;  1OTP A;  1N60 B;  3NVV C;  5MPO C;  1X1O A;  2QEX H;  4UY8 M;  2W3R B;  4KWW A;  2WP4 A;  2OTJ H;  1VQ9 H;  3CCV H;  5GAE N;  1V97 A;  1VQ4 H;  1VQN H;  1Q86 J;  3B9J C;  3CCR H;  2B7Q A;  4AP8 A;  2JBM A;  3EUB 4;  1FFV B;  4EAF A;  3ETR C;  3CC2 H;  1FM0 E;  5JVH J;  4LHM A;  3NS1 C;  3RPF A;  3WNZ A;  2OMD A;  1S72 H;  3OW2 H;  2I14 A;  3CXC H;  1RM6 A;  1NVI E;  3NVY C;  5EP8 A;  3TQV A;  2WK6 A;  2W3S B;  5MLC O;  3G71 H;  1N5X A;  2B7N A;  5HUL A;  1QPR A;  3BII E;  2Q5W E;  3WO0 A;  1K9M J;  1YTE A;  1WYG A;  5EY3 A;  4WF9 J;  3NVW C;  5AYY A;  4WFB J;  2PA2 A;  2QIE A;  1FO4 A;  1YJN H;  3PIO J;  2W55 B;  1SIJ A;  4ZOH A;  4I9A A;  4WFA J;  1YTD A;  5H1S O;  3G4S H;  5GAD N;  3L4P A;  1YI2 H;  2ZJP J;  2E3T A;  4WCE J;  1JRO B;  5JVG J;  1M90 J;  4C80 A;  4X46 A;  3C2O A;  1M1K J;  1O4U A; 
#chains in the Genus database with same CATH homology
 1YJW H;  1Q81 J;  4WFN J;  1VQK H;  3CCM H;  1N8R J;  1WKI A;  4IOC J;  5DM6 J;  1VQM H;  1VQ5 H;  3DLL J;  1K8A J;  1KQS H;  5GAH N;  2ZJR J;  1JJ2 H;  5GAG N;  1YIT H;  3CCQ H;  1K73 J;  1YIJ H;  1Q82 J;  1VQL H;  1VQO H;  1VQ7 H;  1QVG H;  2OTL H;  3CMA H;  3CCJ H;  3CCS H;  3CC4 H;  3CF5 J;  1KC8 J;  5DM7 J;  3G6E H;  1VQ6 H;  3CCE H;  1VQ8 H;  4U67 J;  3CCU H;  1KD1 J;  1QVF H;  3CPW H;  1YHQ H;  2ZJQ J;  1NJI J;  3I55 H;  1W2B H;  3PIP J;  1YJ9 H;  1VQP H;  3CD6 H;  1Y69 K;  3CC7 H;  1Q7Y J;  3J7Z M;  4IOA J;  3CCL H;  3I56 H;  3CME H;  5AN9 F;  5HL7 J;  2QA4 H;  2QEX H;  4UY8 M;  2OTJ H;  1VQ9 H;  3CCV H;  5GAE N;  1VQ4 H;  1VQN H;  1Q86 J;  3CCR H;  3CC2 H;  5JVH J;  1S72 H;  3OW2 H;  3CXC H;  3G71 H;  5MLC O;  1K9M J;  4WF9 J;  4WFB J;  2PA2 A;  1YJN H;  3PIO J;  4WFA J;  5H1S O;  3G4S H;  5GAD N;  1YI2 H;  2ZJP J;  4WCE J;  5JVG J;  1M90 J;  1M1K J;  4IO9 J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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