3CCUH

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482c
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 39
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3ccuH00
3CXCH 3CC2H 1K73J 3CMAH 1Q86J 5HL7J 5AN9F 1Q81J 5H1SO 5JVHJ 3I56H 3CCJH 1VQ6H 3CD6H 1QVGH 1KD1J 3CC7H 1M1KJ 5DM6J 3CCMH 4WFBJ 2ZJRJ 3OW2H 3CCSH 4WF9J 3CCVH 1YJ9H 1VQ7H 1K9MJ 2ZJQJ 2OTLH 1WKIA 3CCEH 1M90J 1Q7YJ 2QA4H 5DM7J 1VQLH 3J7ZM 5GAEN 5GADN 1K8AJ 1YITH 3CCRH 4WFAJ 5MLCO 4WFNJ 1VQMH 2QEXH 3CCLH 2ZJPJ 1N8RJ 5JVGJ 1S72H 4IOAJ 3CC4H 3PIPJ 1W2BH 3G6EH 1VQ8H 1VQOH 1VQ4H 4IOCJ 1JJ2H 1KQSH 1VQ9H 4IO9J 4UY8M 1QVFH 1YJWH 2OTJH 4WCEJ 3DLLJ 3CPWH 3PIOJ 5GAHN 3G4SH 3CCUH 1YHQH 1VQ5H 1YIJH 3CCQH 3CMEH 3CF5J 1VQNH 5GAGN 1NJIJ 1VQPH 3I55H 2PA2A 1YI2H 3G71H 1Y69K 1KC8J 1VQKH 4U67J 1YJNH 1Q82J
chains in the Genus database with same CATH superfamily
3CXCH 4YEKA 1O4UA 1QPQA 3CC2H 1V97A 1K73J 3CMAH 3AMZA 1Q86J 5HL7J 5AN9F 2I1OA 1FFUB 3GNNA 4X46A 2WK5A 4I9AA 1BRWA 1QAPA 1Q81J 1FO4A 5H1SO 5JVHJ 1FMAE 2JBMA 4EAFA 3I56H 3CCJH 3VMMA 4ZOHA 1VQ6H 2I14A 3CD6H 1QPNA 1QVGH 1ZXIB 1KD1J 3CC7H 1N5WB 1OTPA 1M1KJ 5DM6J 1JROB 3AN1A 3CCMH 2W3SB 4WFBJ 2ZJRJ 3OW2H 1FIQC 2B7QA 3NVYC 3EUB4 4USAA 4WF9J 3CCSH 3CCVH 1YJ9H 1VQ7H 1K9MJ 1QPRA 2ZJQJ 1YTDA 2OTLH 1N63B 1WKIA 1DGJA 1JRPB 2QIEA 1VLBA 2J0FA 3CCEH 1M90J 1Q7YJ 2QA4H 2Q5WE 5DM7J 3C2OA 1VQLH 3J7ZM 5GAEN 3C2RA 1FM0E 5GADN 1K8AJ 1YITH 3CCRH 4WFAJ 1WYGA 3C2FA 4XR5A 5MLCO 4WFNJ 1VQMH 5AYXA 4C7ZA 4US8A 2QEXH 3CCLH 2W54B 3RPFA 2ZJPJ 1N8RJ 1AZYA 5JVGJ 5AYYA 3WO1A 1NVIE 1S72H 4IOAJ 3CC4H 1FFVB 3PIPJ 1YTEA 4LHMA 2B7PA 1W2BH 3NS1C 1NVJA 3G6EH 3ETRC 1VQ8H 1VDVA 4YYYA 2W3RB 3SR6C 3H5QA 1VQOH 1UOUA 2B7NA 3AM9A 4GA6A 3L4PA 1SB3A 3C2EA 4AP8A 1N5XA 2W55B 4EADA 4IOCJ 1N60B 1VQ4H 1JJ2H 1KQSH 3C2VA 1VQ9H 5EY3A 3WNZA 4IO9J 4UY8M 4US9A 1QVFH 3BIIE 1QPOA 1YJWH 2OTJH 3NVZC 4WCEJ 5HUPA 3DLLJ 3CPWH 3PIOJ 1N62B 2WK6A 5GAHN 3FAHA 4GA4A 3G4SH 3CCUH 2DSJA 1YHQH 4KWWA 1VQ5H 1N61B 3L0GA 3PAJA 4KWVA 3CCQH 1YIJH 3CMEH 1X1OA 3CF5J 1VQNH 4C7YA 5GAGN 2TPTA 1NJIJ 1RM6A 1VQPH 3I55H 5HUOA 2PA2A 1YI2H 3FC4A 4C80A 3NVVC 1SIJA 3NRZC 3G71H 3WO0A 5EP8A 5HULA 1Y69K 1KC8J 5AYZA 5MPOC 3NVWC 2E3TA 1VQKH 3TQVA 4GA5A 4U67J 1YTKA 1YJNH 3B9JC 2WP4A 1Q82J 2OMDA
chains in the Genus database with same CATH topology
3CXCH 3CC2H 1K73J 3CMAH 1Q86J 5HL7J 5AN9F 1Q81J 5H1SO 5JVHJ 3I56H 3CCJH 1VQ6H 3CD6H 1QVGH 1KD1J 3CC7H 1M1KJ 5DM6J 3CCMH 4WFBJ 2ZJRJ 3OW2H 3CCSH 4WF9J 3CCVH 1YJ9H 1VQ7H 1K9MJ 2ZJQJ 2OTLH 1WKIA 3CCEH 1M90J 1Q7YJ 2QA4H 5DM7J 1VQLH 3J7ZM 5GAEN 5GADN 1K8AJ 1YITH 3CCRH 4WFAJ 5MLCO 4WFNJ 1VQMH 2QEXH 3CCLH 2ZJPJ 1N8RJ 5JVGJ 1S72H 4IOAJ 3CC4H 3PIPJ 1W2BH 3G6EH 1VQ8H 1VQOH 1VQ4H 4IOCJ 1JJ2H 1KQSH 1VQ9H 4IO9J 4UY8M 1QVFH 1YJWH 2OTJH 4WCEJ 3DLLJ 3CPWH 3PIOJ 5GAHN 3G4SH 3CCUH 1YHQH 1VQ5H 1YIJH 3CCQH 3CMEH 3CF5J 1VQNH 5GAGN 1NJIJ 1VQPH 3I55H 2PA2A 1YI2H 3G71H 1Y69K 1KC8J 1VQKH 4U67J 1YJNH 1Q82J
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CXC H;  3CC2 H;  1K73 J;  3CMA H;  1Q86 J;  5HL7 J;  5AN9 F;  1Q81 J;  5H1S O;  5JVH J;  3I56 H;  3CCJ H;  1VQ6 H;  3CD6 H;  1QVG H;  1KD1 J;  3CC7 H;  1M1K J;  5DM6 J;  3CCM H;  4WFB J;  2ZJR J;  3OW2 H;  3CCS H;  4WF9 J;  3CCV H;  1YJ9 H;  1VQ7 H;  1K9M J;  2ZJQ J;  2OTL H;  1WKI A;  3CCE H;  1M90 J;  1Q7Y J;  2QA4 H;  5DM7 J;  1VQL H;  3J7Z M;  5GAE N;  5GAD N;  1K8A J;  1YIT H;  3CCR H;  4WFA J;  5MLC O;  4WFN J;  1VQM H;  2QEX H;  3CCL H;  2ZJP J;  1N8R J;  5JVG J;  1S72 H;  4IOA J;  3CC4 H;  3PIP J;  1W2B H;  3G6E H;  1VQ8 H;  1VQO H;  1VQ4 H;  4IOC J;  1JJ2 H;  1KQS H;  1VQ9 H;  4IO9 J;  4UY8 M;  1QVF H;  1YJW H;  2OTJ H;  4WCE J;  3DLL J;  3CPW H;  3PIO J;  5GAH N;  3G4S H;  3CCU H;  1YHQ H;  1VQ5 H;  1YIJ H;  3CCQ H;  3CME H;  3CF5 J;  1VQN H;  5GAG N;  1NJI J;  1VQP H;  3I55 H;  2PA2 A;  1YI2 H;  3G71 H;  1Y69 K;  1KC8 J;  1VQK H;  4U67 J;  1YJN H;  1Q82 J; 
#chains in the Genus database with same CATH topology
 3CXC H;  4YEK A;  1O4U A;  1QPQ A;  3CC2 H;  1V97 A;  1K73 J;  3CMA H;  3AMZ A;  1Q86 J;  5HL7 J;  5AN9 F;  2I1O A;  1FFU B;  3GNN A;  4X46 A;  2WK5 A;  4I9A A;  1BRW A;  1QAP A;  1Q81 J;  1FO4 A;  5H1S O;  5JVH J;  1FMA E;  2JBM A;  4EAF A;  3I56 H;  3CCJ H;  3VMM A;  4ZOH A;  1VQ6 H;  2I14 A;  3CD6 H;  1QPN A;  1QVG H;  1ZXI B;  1KD1 J;  3CC7 H;  1N5W B;  1OTP A;  1M1K J;  5DM6 J;  1JRO B;  3AN1 A;  3CCM H;  2W3S B;  4WFB J;  2ZJR J;  3OW2 H;  1FIQ C;  2B7Q A;  3NVY C;  3EUB 4;  4USA A;  4WF9 J;  3CCS H;  3CCV H;  1YJ9 H;  1VQ7 H;  1K9M J;  1QPR A;  2ZJQ J;  1YTD A;  2OTL H;  1N63 B;  1WKI A;  1DGJ A;  1JRP B;  2QIE A;  1VLB A;  2J0F A;  3CCE H;  1M90 J;  1Q7Y J;  2QA4 H;  2Q5W E;  5DM7 J;  3C2O A;  1VQL H;  3J7Z M;  5GAE N;  3C2R A;  1FM0 E;  5GAD N;  1K8A J;  1YIT H;  3CCR H;  4WFA J;  1WYG A;  3C2F A;  4XR5 A;  5MLC O;  4WFN J;  1VQM H;  5AYX A;  4C7Z A;  4US8 A;  2QEX H;  3CCL H;  2W54 B;  3RPF A;  2ZJP J;  1N8R J;  1AZY A;  5JVG J;  5AYY A;  3WO1 A;  1NVI E;  1S72 H;  4IOA J;  3CC4 H;  1FFV B;  3PIP J;  1YTE A;  4LHM A;  2B7P A;  1W2B H;  3NS1 C;  1NVJ A;  3G6E H;  3ETR C;  1VQ8 H;  1VDV A;  4YYY A;  2W3R B;  3SR6 C;  3H5Q A;  1VQO H;  1UOU A;  2B7N A;  3AM9 A;  4GA6 A;  3L4P A;  1SB3 A;  3C2E A;  4AP8 A;  1N5X A;  2W55 B;  4EAD A;  4IOC J;  1N60 B;  1VQ4 H;  1JJ2 H;  1KQS H;  3C2V A;  1VQ9 H;  5EY3 A;  3WNZ A;  4IO9 J;  4UY8 M;  4US9 A;  1QVF H;  3BII E;  1QPO A;  1YJW H;  2OTJ H;  3NVZ C;  4WCE J;  5HUP A;  3DLL J;  3CPW H;  3PIO J;  1N62 B;  2WK6 A;  5GAH N;  3FAH A;  4GA4 A;  3G4S H;  3CCU H;  2DSJ A;  1YHQ H;  4KWW A;  1VQ5 H;  1N61 B;  3L0G A;  3PAJ A;  4KWV A;  3CCQ H;  1YIJ H;  3CME H;  1X1O A;  3CF5 J;  1VQN H;  4C7Y A;  5GAG N;  2TPT A;  1NJI J;  1RM6 A;  1VQP H;  3I55 H;  5HUO A;  2PA2 A;  1YI2 H;  3FC4 A;  4C80 A;  3NVV C;  1SIJ A;  3NRZ C;  3G71 H;  3WO0 A;  5EP8 A;  5HUL A;  1Y69 K;  1KC8 J;  5AYZ A;  5MPO C;  3NVW C;  2E3T A;  1VQK H;  3TQV A;  4GA5 A;  4U67 J;  1YTK A;  1YJN H;  3B9J C;  2WP4 A;  1Q82 J;  2OMD A; 
#chains in the Genus database with same CATH homology
 3CXC H;  3CC2 H;  1K73 J;  3CMA H;  1Q86 J;  5HL7 J;  5AN9 F;  1Q81 J;  5H1S O;  5JVH J;  3I56 H;  3CCJ H;  1VQ6 H;  3CD6 H;  1QVG H;  1KD1 J;  3CC7 H;  1M1K J;  5DM6 J;  3CCM H;  4WFB J;  2ZJR J;  3OW2 H;  3CCS H;  4WF9 J;  3CCV H;  1YJ9 H;  1VQ7 H;  1K9M J;  2ZJQ J;  2OTL H;  1WKI A;  3CCE H;  1M90 J;  1Q7Y J;  2QA4 H;  5DM7 J;  1VQL H;  3J7Z M;  5GAE N;  5GAD N;  1K8A J;  1YIT H;  3CCR H;  4WFA J;  5MLC O;  4WFN J;  1VQM H;  2QEX H;  3CCL H;  2ZJP J;  1N8R J;  5JVG J;  1S72 H;  4IOA J;  3CC4 H;  3PIP J;  1W2B H;  3G6E H;  1VQ8 H;  1VQO H;  1VQ4 H;  4IOC J;  1JJ2 H;  1KQS H;  1VQ9 H;  4IO9 J;  4UY8 M;  1QVF H;  1YJW H;  2OTJ H;  4WCE J;  3DLL J;  3CPW H;  3PIO J;  5GAH N;  3G4S H;  3CCU H;  1YHQ H;  1VQ5 H;  1YIJ H;  3CCQ H;  3CME H;  3CF5 J;  1VQN H;  5GAG N;  1NJI J;  1VQP H;  3I55 H;  2PA2 A;  1YI2 H;  3G71 H;  1Y69 K;  1KC8 J;  1VQK H;  4U67 J;  1YJN H;  1Q82 J; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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