3CPWH

The structure of the antibiotic linezolid bound to the large ribosomal subunit of haloarcula marismortui
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
171
structure length
160
Chain Sequence
KPASMYRDIDKPAYTRREYITGIPGSKIAQHKMGRKQKDADDYPVQISLIVEETVQLRHGSLEASRLSANRHLIKELGEEGDYKMTLRKFPHQVLRENKDGMRAAFGKIVGTAARVQAGEQLFTAYCNVEDAEHVKEAFRRAYNKITPSCRIKVERGEEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 40
structure length 160
sequence length 171
ec nomenclature
pdb deposition date 2008-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
H PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3cpwH00
5DM7J 1K8AJ 1VQ9H 1Q86J 4WFNJ 5MLCO 5H1SO 1Q82J 5JVHJ 3CC7H 1QVGH 4U67J 1YIJH 1VQ7H 4IO9J 1KC8J 3CC2H 3CCQH 3CCLH 2QEXH 1N8RJ 5GAHN 5GAGN 5DM6J 4WFBJ 1YHQH 4WCEJ 1M90J 1K9MJ 1YJNH 3CMEH 1YITH 3CCUH 1WKIA 3I56H 1NJIJ 3CD6H 5HL7J 1VQ6H 3CCMH 3OW2H 1KD1J 3CCRH 3CCJH 2PA2A 2ZJPJ 3G4SH 2ZJQJ 1M1KJ 1VQMH 4WF9J 1JJ2H 3I55H 1QVFH 3PIOJ 1Q81J 1VQ8H 3J7ZM 3CPWH 4IOAJ 5AN9F 2OTLH 1VQOH 3DLLJ 4UY8M 3CCVH 1Q7YJ 2ZJRJ 1VQ5H 3CCEH 1YJWH 1VQLH 1KQSH 3G71H 3CF5J 2QA4H 5JVGJ 1K73J 4IOCJ 5GAEN 1VQ4H 3PIPJ 5GADN 3CXCH 1S72H 1Y69K 1YJ9H 1W2BH 1VQKH 3CC4H 1VQPH 1YI2H 3CMAH 2OTJH 3CCSH 4WFAJ 3G6EH 1VQNH
chains in the Genus database with same CATH superfamily
5AYZA 3AN1A 5DM7J 1DGJA 1K8AJ 4C7ZA 2Q5WE 1VQ9H 1Q86J 3L4PA 2JBMA 5EY3A 5AYYA 1QPQA 5EP8A 3VMMA 5H1SO 1UOUA 5MLCO 4WFNJ 2I14A 4EADA 3WO1A 5JVHJ 1X1OA 3NVZC 4C80A 3C2RA 3CC7H 1QVGH 4U67J 2WP4A 3RPFA 1N62B 1YIJH 1VQ7H 4IO9J 1O4UA 1V97A 1FFUB 4C7YA 1KC8J 3CC2H 1ZXIB 2E3TA 3NVYC 3PAJA 3BIIE 3CCLH 1JRPB 2I1OA 2W3RB 5GAHN 2QEXH 3CCQH 2TPTA 1N8RJ 5GAGN 1VDVA 1N5XA 1FO4A 3TQVA 2OMDA 2W3SB 1N61B 5DM6J 4WFBJ 1YHQH 4WCEJ 5HUOA 1VLBA 3G6EH 1M90J 1K9MJ 3FC4A 2WK6A 3SR6C 3CCSH 1QPNA 1YTEA 3ETRC 1YJNH 4YEKA 3CMEH 1JROB 1YITH 3CCUH 1WKIA 3EUB4 1YTKA 3I56H 2B7QA 4GA4A 1NJIJ 3CD6H 3AM9A 1FIQC 4AP8A 5HL7J 1Q82J 1VQ6H 3CCMH 5HULA 3OW2H 1N5WB 1QAPA 1KD1J 4GA5A 3CCRH 2WK5A 3CCJH 1FMAE 4XR5A 4US9A 4US8A 3G4SH 2ZJQJ 1M1KJ 1VQMH 1FFVB 3NVWC 4WF9J 1QPOA 2B7PA 1JJ2H 3NVVC 3I55H 1QVFH 3PIOJ 3NRZC 1Q81J 1QPRA 1VQ8H 1N63B 3J7ZM 3CPWH 3FAHA 3B9JC 1OTPA 4IOAJ 5AN9F 2OTLH 1VQOH 1FM0E 3DLLJ 2W55B 4USAA 4UY8M 4I9AA 1N60B 3CCVH 1Q7YJ 2ZJRJ 1NVJA 1VQ5H 3CCEH 2W54B 2QIEA 1YJWH 1BRWA 1AZYA 3NS1C 1KQSH 3C2EA 1VQLH 3L0GA 3G71H 3CF5J 2QA4H 1WYGA 5JVGJ 1K73J 4IOCJ 5GAEN 1RM6A 1VQ4H 4GA6A 4LHMA 3GNNA 3C2VA 4X46A 3WO0A 3C2FA 4ZOHA 5AYXA 5HUPA 3PIPJ 4KWWA 5GADN 3CXCH 2DSJA 2B7NA 5MPOC 4KWVA 1S72H 3H5QA 1Y69K 1YJ9H 3WNZA 1W2BH 1SB3A 4YYYA 2J0FA 1VQKH 3CC4H 1NVIE 1VQPH 1YI2H 1YTDA 3C2OA 3CMAH 2OTJH 4EAFA 2ZJPJ 4WFAJ 3AMZA 2PA2A 1VQNH 1SIJA
chains in the Genus database with same CATH topology
5DM7J 1K8AJ 1VQ9H 1Q86J 4WFNJ 5MLCO 5H1SO 1Q82J 5JVHJ 3CC7H 1QVGH 4U67J 1YIJH 1VQ7H 4IO9J 1KC8J 3CC2H 3CCQH 3CCLH 2QEXH 1N8RJ 5GAHN 5GAGN 5DM6J 4WFBJ 1YHQH 4WCEJ 1M90J 1K9MJ 1YJNH 3CMEH 1YITH 3CCUH 1WKIA 3I56H 1NJIJ 3CD6H 5HL7J 1VQ6H 3CCMH 3OW2H 1KD1J 3CCRH 3CCJH 2PA2A 2ZJPJ 3G4SH 2ZJQJ 1M1KJ 1VQMH 4WF9J 1JJ2H 3I55H 1QVFH 3PIOJ 1Q81J 1VQ8H 3J7ZM 3CPWH 4IOAJ 5AN9F 2OTLH 1VQOH 3DLLJ 4UY8M 3CCVH 1Q7YJ 2ZJRJ 1VQ5H 3CCEH 1YJWH 1VQLH 1KQSH 3G71H 3CF5J 2QA4H 5JVGJ 1K73J 4IOCJ 5GAEN 1VQ4H 3PIPJ 5GADN 3CXCH 1S72H 1Y69K 1YJ9H 1W2BH 1VQKH 3CC4H 1VQPH 1YI2H 3CMAH 2OTJH 3CCSH 4WFAJ 3G6EH 1VQNH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DM7 J;  1K8A J;  1VQ9 H;  1Q86 J;  4WFN J;  5MLC O;  5H1S O;  1Q82 J;  5JVH J;  3CC7 H;  1QVG H;  4U67 J;  1YIJ H;  1VQ7 H;  4IO9 J;  1KC8 J;  3CC2 H;  3CCQ H;  3CCL H;  2QEX H;  1N8R J;  5GAH N;  5GAG N;  5DM6 J;  4WFB J;  1YHQ H;  4WCE J;  1M90 J;  1K9M J;  1YJN H;  3CME H;  1YIT H;  3CCU H;  1WKI A;  3I56 H;  1NJI J;  3CD6 H;  5HL7 J;  1VQ6 H;  3CCM H;  3OW2 H;  1KD1 J;  3CCR H;  3CCJ H;  2PA2 A;  2ZJP J;  3G4S H;  2ZJQ J;  1M1K J;  1VQM H;  4WF9 J;  1JJ2 H;  3I55 H;  1QVF H;  3PIO J;  1Q81 J;  1VQ8 H;  3J7Z M;  3CPW H;  4IOA J;  5AN9 F;  2OTL H;  1VQO H;  3DLL J;  4UY8 M;  3CCV H;  1Q7Y J;  2ZJR J;  1VQ5 H;  3CCE H;  1YJW H;  1VQL H;  1KQS H;  3G71 H;  3CF5 J;  2QA4 H;  5JVG J;  1K73 J;  4IOC J;  5GAE N;  1VQ4 H;  3PIP J;  5GAD N;  3CXC H;  1S72 H;  1Y69 K;  1YJ9 H;  1W2B H;  1VQK H;  3CC4 H;  1VQP H;  1YI2 H;  3CMA H;  2OTJ H;  3CCS H;  4WFA J;  3G6E H;  1VQN H; 
#chains in the Genus database with same CATH topology
 5AYZ A;  3AN1 A;  5DM7 J;  1DGJ A;  1K8A J;  4C7Z A;  2Q5W E;  1VQ9 H;  1Q86 J;  3L4P A;  2JBM A;  5EY3 A;  5AYY A;  1QPQ A;  5EP8 A;  3VMM A;  5H1S O;  1UOU A;  5MLC O;  4WFN J;  2I14 A;  4EAD A;  3WO1 A;  5JVH J;  1X1O A;  3NVZ C;  4C80 A;  3C2R A;  3CC7 H;  1QVG H;  4U67 J;  2WP4 A;  3RPF A;  1N62 B;  1YIJ H;  1VQ7 H;  4IO9 J;  1O4U A;  1V97 A;  1FFU B;  4C7Y A;  1KC8 J;  3CC2 H;  1ZXI B;  2E3T A;  3NVY C;  3PAJ A;  3BII E;  3CCL H;  1JRP B;  2I1O A;  2W3R B;  5GAH N;  2QEX H;  3CCQ H;  2TPT A;  1N8R J;  5GAG N;  1VDV A;  1N5X A;  1FO4 A;  3TQV A;  2OMD A;  2W3S B;  1N61 B;  5DM6 J;  4WFB J;  1YHQ H;  4WCE J;  5HUO A;  1VLB A;  3G6E H;  1M90 J;  1K9M J;  3FC4 A;  2WK6 A;  3SR6 C;  3CCS H;  1QPN A;  1YTE A;  3ETR C;  1YJN H;  4YEK A;  3CME H;  1JRO B;  1YIT H;  3CCU H;  1WKI A;  3EUB 4;  1YTK A;  3I56 H;  2B7Q A;  4GA4 A;  1NJI J;  3CD6 H;  3AM9 A;  1FIQ C;  4AP8 A;  5HL7 J;  1Q82 J;  1VQ6 H;  3CCM H;  5HUL A;  3OW2 H;  1N5W B;  1QAP A;  1KD1 J;  4GA5 A;  3CCR H;  2WK5 A;  3CCJ H;  1FMA E;  4XR5 A;  4US9 A;  4US8 A;  3G4S H;  2ZJQ J;  1M1K J;  1VQM H;  1FFV B;  3NVW C;  4WF9 J;  1QPO A;  2B7P A;  1JJ2 H;  3NVV C;  3I55 H;  1QVF H;  3PIO J;  3NRZ C;  1Q81 J;  1QPR A;  1VQ8 H;  1N63 B;  3J7Z M;  3CPW H;  3FAH A;  3B9J C;  1OTP A;  4IOA J;  5AN9 F;  2OTL H;  1VQO H;  1FM0 E;  3DLL J;  2W55 B;  4USA A;  4UY8 M;  4I9A A;  1N60 B;  3CCV H;  1Q7Y J;  2ZJR J;  1NVJ A;  1VQ5 H;  3CCE H;  2W54 B;  2QIE A;  1YJW H;  1BRW A;  1AZY A;  3NS1 C;  1KQS H;  3C2E A;  1VQL H;  3L0G A;  3G71 H;  3CF5 J;  2QA4 H;  1WYG A;  5JVG J;  1K73 J;  4IOC J;  5GAE N;  1RM6 A;  1VQ4 H;  4GA6 A;  4LHM A;  3GNN A;  3C2V A;  4X46 A;  3WO0 A;  3C2F A;  4ZOH A;  5AYX A;  5HUP A;  3PIP J;  4KWW A;  5GAD N;  3CXC H;  2DSJ A;  2B7N A;  5MPO C;  4KWV A;  1S72 H;  3H5Q A;  1Y69 K;  1YJ9 H;  3WNZ A;  1W2B H;  1SB3 A;  4YYY A;  2J0F A;  1VQK H;  3CC4 H;  1NVI E;  1VQP H;  1YI2 H;  1YTD A;  3C2O A;  3CMA H;  2OTJ H;  4EAF A;  2ZJP J;  4WFA J;  3AMZ A;  2PA2 A;  1VQN H;  1SIJ A; 
#chains in the Genus database with same CATH homology
 5DM7 J;  1K8A J;  1VQ9 H;  1Q86 J;  4WFN J;  5MLC O;  5H1S O;  1Q82 J;  5JVH J;  3CC7 H;  1QVG H;  4U67 J;  1YIJ H;  1VQ7 H;  4IO9 J;  1KC8 J;  3CC2 H;  3CCQ H;  3CCL H;  2QEX H;  1N8R J;  5GAH N;  5GAG N;  5DM6 J;  4WFB J;  1YHQ H;  4WCE J;  1M90 J;  1K9M J;  1YJN H;  3CME H;  1YIT H;  3CCU H;  1WKI A;  3I56 H;  1NJI J;  3CD6 H;  5HL7 J;  1VQ6 H;  3CCM H;  3OW2 H;  1KD1 J;  3CCR H;  3CCJ H;  2PA2 A;  2ZJP J;  3G4S H;  2ZJQ J;  1M1K J;  1VQM H;  4WF9 J;  1JJ2 H;  3I55 H;  1QVF H;  3PIO J;  1Q81 J;  1VQ8 H;  3J7Z M;  3CPW H;  4IOA J;  5AN9 F;  2OTL H;  1VQO H;  3DLL J;  4UY8 M;  3CCV H;  1Q7Y J;  2ZJR J;  1VQ5 H;  3CCE H;  1YJW H;  1VQL H;  1KQS H;  3G71 H;  3CF5 J;  2QA4 H;  5JVG J;  1K73 J;  4IOC J;  5GAE N;  1VQ4 H;  3PIP J;  5GAD N;  3CXC H;  1S72 H;  1Y69 K;  1YJ9 H;  1W2B H;  1VQK H;  3CC4 H;  1VQP H;  1YI2 H;  3CMA H;  2OTJ H;  3CCS H;  4WFA J;  3G6E H;  1VQN H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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