3CXCH

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
167
structure length
156
Chain Sequence
KPGAMYRNSSKPAYTRREYISGIPGKKIAQFDMGNNGAGPTYPAQVELVVEKPVQIRHNALEAARVAANRYVQNSGAAANYKFRIRKFPFHVIRENKDGMRAPFGKPVGTAARVHGANHIFIAWVNPDPNVEEAWRRAKMKVTPTINIDSSPAGNA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 27
structure length 156
sequence length 167
ec nomenclature
pdb deposition date 2008-04-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3cxcH00
5JVGJ 1VQ5H 1Q86J 3CCVH 1Q7YJ 1VQ4H 1KD1J 3CD6H 5DM6J 1YJWH 1S72H 3CCUH 1VQKH 1VQNH 2OTJH 3J7ZM 1VQOH 1JJ2H 3G6EH 2PA2A 5HL7J 4UY8M 1NJIJ 2QA4H 5DM7J 1VQ8H 3PIOJ 2ZJPJ 4WFBJ 4U67J 1VQMH 3CCQH 5GAGN 1Q81J 1K73J 1VQPH 5H1SO 5MLCO 1M90J 1YJ9H 3CPWH 1Y69K 1YI2H 1K9MJ 1WKIA 5GADN 4IOAJ 1N8RJ 5AN9F 3CCMH 1VQ9H 3PIPJ 1M1KJ 1KC8J 2OTLH 1W2BH 1QVGH 3CCSH 4IO9J 4IOCJ 3I55H 1KQSH 1K8AJ 4WFAJ 3CC7H 1YHQH 1YITH 1QVFH 3CCJH 1VQLH 3CC4H 3OW2H 3G4SH 4WF9J 3CCRH 3CC2H 2ZJQJ 3CMAH 2ZJRJ 3G71H 4WFNJ 1VQ7H 1YJNH 3CMEH 3DLLJ 3CXCH 5JVHJ 3CCLH 1VQ6H 4WCEJ 3CF5J 5GAHN 1Q82J 1YIJH 5GAEN 3CCEH 2QEXH 3I56H
chains in the Genus database with same CATH superfamily
3PAJA 1JRPB 5JVGJ 1VQ5H 1QPQA 1NVJA 3ETRC 1Q86J 1X1OA 1V97A 1SB3A 5HULA 3CCVH 1Q7YJ 1VQ4H 1NVIE 1BRWA 1KD1J 3SR6C 3AMZA 3C2OA 3CD6H 5DM6J 1QPOA 1YJWH 1S72H 2I1OA 3L0GA 3CCUH 2W55B 1VQKH 1FFVB 5AYXA 4X46A 3GNNA 2OMDA 1N5WB 1VQNH 3NVWC 3CCMH 2OTJH 3J7ZM 1N62B 1VQOH 1JJ2H 3G6EH 3NRZC 1FFUB 2PA2A 5HL7J 2WK5A 4US9A 1NJIJ 1FO4A 4UY8M 4AP8A 5DM7J 2QA4H 1QAPA 1VQ8H 3PIOJ 2ZJPJ 1OTPA 1YTEA 4WFBJ 4U67J 1AZYA 3NVZC 4GA5A 3CCQH 1JROB 5AYZA 5GAGN 1VQMH 4C7ZA 1Q81J 3FC4A 1K73J 1O4UA 3AM9A 1FIQC 1VQPH 2B7NA 3NVYC 5H1SO 1FM0E 5MLCO 2W3SB 3NVVC 3WNZA 1M90J 1YJ9H 5AYYA 2DSJA 5EP8A 3CPWH 2WK6A 1YTKA 1Y69K 1DGJA 2E3TA 1UOUA 1YI2H 3FAHA 2Q5WE 4ZOHA 1K9MJ 1QPRA 1WKIA 5GADN 4IOAJ 3H5QA 2WP4A 1VDVA 3C2VA 1N8RJ 5AN9F 4LHMA 4C80A 3WO0A 3WO1A 4GA4A 3AN1A 4I9AA 4XR5A 4C7YA 4YYYA 1ZXIB 3PIPJ 1VQ9H 1RM6A 2J0FA 2B7PA 1M1KJ 1KC8J 2OTLH 3C2RA 4KWVA 1W2BH 5HUPA 4KWWA 1N61B 1QVGH 5EY3A 3CCSH 4IO9J 1WYGA 2QIEA 4IOCJ 3I55H 1SIJA 1FMAE 1VLBA 1KQSH 1YTDA 1N63B 1K8AJ 4WFAJ 2W3RB 4EADA 1YHQH 3CC7H 1YITH 1QVFH 3BIIE 3CCJH 3C2EA 3C2FA 1VQLH 3TQVA 4YEKA 2W54B 4GA6A 2JBMA 4USAA 3CC4H 3OW2H 3G4SH 4WF9J 3CCRH 3CC2H 2ZJQJ 1N5XA 3CMAH 4US8A 3EUB4 2ZJRJ 3G71H 4WFNJ 1VQ7H 1YJNH 3CMEH 2TPTA 3DLLJ 2B7QA 1N60B 2I14A 3RPFA 3CXCH 4EAFA 3B9JC 5JVHJ 3CCLH 1VQ6H 5MPOC 4WCEJ 1QPNA 3VMMA 3CF5J 3NS1C 5GAHN 1Q82J 1YIJH 5HUOA 5GAEN 3I56H 3CCEH 2QEXH 3L4PA
chains in the Genus database with same CATH topology
5JVGJ 1VQ5H 1Q86J 3CCVH 1Q7YJ 1VQ4H 1KD1J 3CD6H 5DM6J 1YJWH 1S72H 3CCUH 1VQKH 1VQNH 2OTJH 3J7ZM 1VQOH 1JJ2H 3G6EH 2PA2A 5HL7J 4UY8M 1NJIJ 2QA4H 5DM7J 1VQ8H 3PIOJ 2ZJPJ 4WFBJ 4U67J 1VQMH 3CCQH 5GAGN 1Q81J 1K73J 1VQPH 5H1SO 5MLCO 1M90J 1YJ9H 3CPWH 1Y69K 1YI2H 1K9MJ 1WKIA 5GADN 4IOAJ 1N8RJ 5AN9F 3CCMH 1VQ9H 3PIPJ 1M1KJ 1KC8J 2OTLH 1W2BH 1QVGH 3CCSH 4IO9J 4IOCJ 3I55H 1KQSH 1K8AJ 4WFAJ 3CC7H 1YHQH 1YITH 1QVFH 3CCJH 1VQLH 3CC4H 3OW2H 3G4SH 4WF9J 3CCRH 3CC2H 2ZJQJ 3CMAH 2ZJRJ 3G71H 4WFNJ 1VQ7H 1YJNH 3CMEH 3DLLJ 3CXCH 5JVHJ 3CCLH 1VQ6H 4WCEJ 3CF5J 5GAHN 1Q82J 1YIJH 5GAEN 3CCEH 2QEXH 3I56H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JVG J;  1VQ5 H;  1Q86 J;  3CCV H;  1Q7Y J;  1VQ4 H;  1KD1 J;  3CD6 H;  5DM6 J;  1YJW H;  1S72 H;  3CCU H;  1VQK H;  1VQN H;  2OTJ H;  3J7Z M;  1VQO H;  1JJ2 H;  3G6E H;  2PA2 A;  5HL7 J;  4UY8 M;  1NJI J;  2QA4 H;  5DM7 J;  1VQ8 H;  3PIO J;  2ZJP J;  4WFB J;  4U67 J;  1VQM H;  3CCQ H;  5GAG N;  1Q81 J;  1K73 J;  1VQP H;  5H1S O;  5MLC O;  1M90 J;  1YJ9 H;  3CPW H;  1Y69 K;  1YI2 H;  1K9M J;  1WKI A;  5GAD N;  4IOA J;  1N8R J;  5AN9 F;  3CCM H;  1VQ9 H;  3PIP J;  1M1K J;  1KC8 J;  2OTL H;  1W2B H;  1QVG H;  3CCS H;  4IO9 J;  4IOC J;  3I55 H;  1KQS H;  1K8A J;  4WFA J;  3CC7 H;  1YHQ H;  1YIT H;  1QVF H;  3CCJ H;  1VQL H;  3CC4 H;  3OW2 H;  3G4S H;  4WF9 J;  3CCR H;  3CC2 H;  2ZJQ J;  3CMA H;  2ZJR J;  3G71 H;  4WFN J;  1VQ7 H;  1YJN H;  3CME H;  3DLL J;  3CXC H;  5JVH J;  3CCL H;  1VQ6 H;  4WCE J;  3CF5 J;  5GAH N;  1Q82 J;  1YIJ H;  5GAE N;  3CCE H;  2QEX H;  3I56 H; 
#chains in the Genus database with same CATH topology
 3PAJ A;  1JRP B;  5JVG J;  1VQ5 H;  1QPQ A;  1NVJ A;  3ETR C;  1Q86 J;  1X1O A;  1V97 A;  1SB3 A;  5HUL A;  3CCV H;  1Q7Y J;  1VQ4 H;  1NVI E;  1BRW A;  1KD1 J;  3SR6 C;  3AMZ A;  3C2O A;  3CD6 H;  5DM6 J;  1QPO A;  1YJW H;  1S72 H;  2I1O A;  3L0G A;  3CCU H;  2W55 B;  1VQK H;  1FFV B;  5AYX A;  4X46 A;  3GNN A;  2OMD A;  1N5W B;  1VQN H;  3NVW C;  3CCM H;  2OTJ H;  3J7Z M;  1N62 B;  1VQO H;  1JJ2 H;  3G6E H;  3NRZ C;  1FFU B;  2PA2 A;  5HL7 J;  2WK5 A;  4US9 A;  1NJI J;  1FO4 A;  4UY8 M;  4AP8 A;  5DM7 J;  2QA4 H;  1QAP A;  1VQ8 H;  3PIO J;  2ZJP J;  1OTP A;  1YTE A;  4WFB J;  4U67 J;  1AZY A;  3NVZ C;  4GA5 A;  3CCQ H;  1JRO B;  5AYZ A;  5GAG N;  1VQM H;  4C7Z A;  1Q81 J;  3FC4 A;  1K73 J;  1O4U A;  3AM9 A;  1FIQ C;  1VQP H;  2B7N A;  3NVY C;  5H1S O;  1FM0 E;  5MLC O;  2W3S B;  3NVV C;  3WNZ A;  1M90 J;  1YJ9 H;  5AYY A;  2DSJ A;  5EP8 A;  3CPW H;  2WK6 A;  1YTK A;  1Y69 K;  1DGJ A;  2E3T A;  1UOU A;  1YI2 H;  3FAH A;  2Q5W E;  4ZOH A;  1K9M J;  1QPR A;  1WKI A;  5GAD N;  4IOA J;  3H5Q A;  2WP4 A;  1VDV A;  3C2V A;  1N8R J;  5AN9 F;  4LHM A;  4C80 A;  3WO0 A;  3WO1 A;  4GA4 A;  3AN1 A;  4I9A A;  4XR5 A;  4C7Y A;  4YYY A;  1ZXI B;  3PIP J;  1VQ9 H;  1RM6 A;  2J0F A;  2B7P A;  1M1K J;  1KC8 J;  2OTL H;  3C2R A;  4KWV A;  1W2B H;  5HUP A;  4KWW A;  1N61 B;  1QVG H;  5EY3 A;  3CCS H;  4IO9 J;  1WYG A;  2QIE A;  4IOC J;  3I55 H;  1SIJ A;  1FMA E;  1VLB A;  1KQS H;  1YTD A;  1N63 B;  1K8A J;  4WFA J;  2W3R B;  4EAD A;  1YHQ H;  3CC7 H;  1YIT H;  1QVF H;  3BII E;  3CCJ H;  3C2E A;  3C2F A;  1VQL H;  3TQV A;  4YEK A;  2W54 B;  4GA6 A;  2JBM A;  4USA A;  3CC4 H;  3OW2 H;  3G4S H;  4WF9 J;  3CCR H;  3CC2 H;  2ZJQ J;  1N5X A;  3CMA H;  4US8 A;  3EUB 4;  2ZJR J;  3G71 H;  4WFN J;  1VQ7 H;  1YJN H;  3CME H;  2TPT A;  3DLL J;  2B7Q A;  1N60 B;  2I14 A;  3RPF A;  3CXC H;  4EAF A;  3B9J C;  5JVH J;  3CCL H;  1VQ6 H;  5MPO C;  4WCE J;  1QPN A;  3VMM A;  3CF5 J;  3NS1 C;  5GAH N;  1Q82 J;  1YIJ H;  5HUO A;  5GAE N;  3I56 H;  3CCE H;  2QEX H;  3L4P A; 
#chains in the Genus database with same CATH homology
 5JVG J;  1VQ5 H;  1Q86 J;  3CCV H;  1Q7Y J;  1VQ4 H;  1KD1 J;  3CD6 H;  5DM6 J;  1YJW H;  1S72 H;  3CCU H;  1VQK H;  1VQN H;  2OTJ H;  3J7Z M;  1VQO H;  1JJ2 H;  3G6E H;  2PA2 A;  5HL7 J;  4UY8 M;  1NJI J;  2QA4 H;  5DM7 J;  1VQ8 H;  3PIO J;  2ZJP J;  4WFB J;  4U67 J;  1VQM H;  3CCQ H;  5GAG N;  1Q81 J;  1K73 J;  1VQP H;  5H1S O;  5MLC O;  1M90 J;  1YJ9 H;  3CPW H;  1Y69 K;  1YI2 H;  1K9M J;  1WKI A;  5GAD N;  4IOA J;  1N8R J;  5AN9 F;  3CCM H;  1VQ9 H;  3PIP J;  1M1K J;  1KC8 J;  2OTL H;  1W2B H;  1QVG H;  3CCS H;  4IO9 J;  4IOC J;  3I55 H;  1KQS H;  1K8A J;  4WFA J;  3CC7 H;  1YHQ H;  1YIT H;  1QVF H;  3CCJ H;  1VQL H;  3CC4 H;  3OW2 H;  3G4S H;  4WF9 J;  3CCR H;  3CC2 H;  2ZJQ J;  3CMA H;  2ZJR J;  3G71 H;  4WFN J;  1VQ7 H;  1YJN H;  3CME H;  3DLL J;  3CXC H;  5JVH J;  3CCL H;  1VQ6 H;  4WCE J;  3CF5 J;  5GAH N;  1Q82 J;  1YIJ H;  5GAE N;  3CCE H;  2QEX H;  3I56 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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