3PIOJ

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 17
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
136
structure length
136
Chain Sequence
KRTKFRKQFRGRMTGDAKGGDYVAFGDYGLIAMEPAWIKSNQIEACRIVMSRHFRRGGKIYIRIFPDKPVTKKPAETRMGKGKGAVEYWVSVVKPGRVMFEVAGVTEEQAKEAFRLAGHKLPIQTKMVKREVYDEA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 17
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
J PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3pioJ01
4WF9J 3CF5J 1K9MJ 1S72H 4IOAJ 2PA2A 1Q86J 1VQ8H 3CCUH 1YJ9H 2ZJPJ 1KQSH 5GAEN 4UY8M 1YJNH 3CCEH 1YHQH 5AN9F 1KC8J 1W2BH 3PIOJ 3CMAH 3CC7H 5GADN 2QEXH 4WFBJ 4IOCJ 1YITH 1JJ2H 3OW2H 1VQ4H 1VQKH 3J7ZM 1Q82J 3CCRH 5MLCO 5DM7J 1VQMH 4U67J 4WCEJ 1VQ7H 1YIJH 1QVGH 2OTJH 3CD6H 1Y69K 1N8RJ 3PIPJ 2ZJRJ 2QA4H 3CC4H 4WFAJ 1WKIA 3CCQH 3CPWH 1VQ9H 3CCMH 3CCLH 5HL7J 1VQNH 5JVHJ 1QVFH 3G6EH 3G71H 3CCJH 5JVGJ 1NJIJ 1K8AJ 2OTLH 1YI2H 3I55H 3CXCH 4IO9J 2ZJQJ 3DLLJ 3CCVH 3CC2H 1YJWH 3CCSH 5GAGN 1VQLH 1KD1J 5GAHN 1VQPH 1M90J 3I56H 1Q81J 1VQOH 3CMEH 1VQ6H 1M1KJ 5H1SO 1Q7YJ 1K73J 5DM6J 4WFNJ 3G4SH 1VQ5H
chains in the Genus database with same CATH superfamily
4WF9J 3CF5J 4KWWA 1K9MJ 1S72H 4IOAJ 2PA2A 4AP8A 4EAFA 3G4SH 2I1OA 3NRZC 4C7YA 1FM0E 2Q5WE 1N62B 4US9A 5AYYA 3PAJA 1ZXIB 1Q86J 2OMDA 3C2RA 1VQ8H 3CCUH 5HUOA 4XR5A 3ETRC 4EADA 1FMAE 1YJ9H 2ZJPJ 1KQSH 3C2FA 5GAEN 5AYXA 4UY8M 1O4UA 1NVJA 1FO4A 3C2OA 1NVIE 4YEKA 1YJNH 1QPRA 1VDVA 3CCEH 2B7QA 4US8A 5AN9F 1YHQH 1KC8J 2W55B 4GA6A 3NS1C 4YYYA 1W2BH 1WYGA 3PIOJ 3AN1A 3CMAH 3CC7H 3L0GA 5GADN 3FC4A 1BRWA 2W3RB 2W3SB 2QEXH 1N63B 4WFBJ 4IOCJ 1YITH 1QPOA 1OTPA 1V97A 3BIIE 2WK5A 3WO0A 3EUB4 1JJ2H 1N60B 2I14A 3OW2H 4KWVA 1VQ4H 3L4PA 1VQKH 3J7ZM 3WO1A 5AYZA 3VMMA 1YTKA 5EY3A 4I9AA 1FFUB 3RPFA 1Q82J 2WP4A 5MPOC 3CCRH 1QPQA 5MLCO 5DM7J 1VQMH 4U67J 3NVYC 4WCEJ 1VQ7H 3FAHA 1YIJH 4C7ZA 1QVGH 2OTJH 3CD6H 4X46A 2J0FA 1Y69K 1QAPA 3AM9A 1N8RJ 3C2VA 3PIPJ 2ZJRJ 2QA4H 3CC4H 2E3TA 2QIEA 1JROB 1FFVB 5HUPA 1N61B 4WFAJ 2TPTA 4GA4A 1WKIA 2B7NA 3CCQH 3CPWH 1YTDA 3H5QA 1YTEA 1VQ9H 3CCMH 3CCLH 5HL7J 1VQNH 5JVHJ 1QVFH 1QPNA 3G6EH 3G71H 3CCJH 5JVGJ 1NJIJ 1K8AJ 2OTLH 2DSJA 1UOUA 1YI2H 4C80A 4ZOHA 1N5WB 3I55H 3AMZA 5EP8A 3CXCH 1JRPB 4IO9J 3NVWC 2JBMA 2ZJQJ 3DLLJ 3CCVH 3CC2H 1X1OA 1YJWH 3CCSH 5HULA 5GAGN 4GA5A 4LHMA 1VQLH 1KD1J 5GAHN 2W54B 4USAA 1VQPH 1DGJA 3GNNA 1VLBA 1FIQC 1M90J 3I56H 1N5XA 1AZYA 3C2EA 1Q81J 1VQOH 3CMEH 3NVZC 2B7PA 1SIJA 2WK6A 3SR6C 3TQVA 1VQ6H 1RM6A 1M1KJ 1SB3A 3NVVC 5H1SO 1Q7YJ 1K73J 5DM6J 3B9JC 4WFNJ 3WNZA 1VQ5H
chains in the Genus database with same CATH topology
4WF9J 3CF5J 1K9MJ 1S72H 4IOAJ 2PA2A 1Q86J 1VQ8H 3CCUH 1YJ9H 2ZJPJ 1KQSH 5GAEN 4UY8M 1YJNH 3CCEH 1YHQH 5AN9F 1KC8J 1W2BH 3PIOJ 3CMAH 3CC7H 5GADN 2QEXH 4WFBJ 4IOCJ 1YITH 1JJ2H 3OW2H 1VQ4H 1VQKH 3J7ZM 1Q82J 3CCRH 5MLCO 5DM7J 1VQMH 4U67J 4WCEJ 1VQ7H 1YIJH 1QVGH 2OTJH 3CD6H 1Y69K 1N8RJ 3PIPJ 2ZJRJ 2QA4H 3CC4H 4WFAJ 1WKIA 3CCQH 3CPWH 1VQ9H 3CCMH 3CCLH 5HL7J 1VQNH 5JVHJ 1QVFH 3G6EH 3G71H 3CCJH 5JVGJ 1NJIJ 1K8AJ 2OTLH 1YI2H 3I55H 3CXCH 4IO9J 2ZJQJ 3DLLJ 3CCVH 3CC2H 1YJWH 3CCSH 5GAGN 1VQLH 1KD1J 5GAHN 1VQPH 1M90J 3I56H 1Q81J 1VQOH 3CMEH 1VQ6H 1M1KJ 5H1SO 1Q7YJ 1K73J 5DM6J 4WFNJ 3G4SH 1VQ5H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WF9 J;  3CF5 J;  1K9M J;  1S72 H;  4IOA J;  2PA2 A;  1Q86 J;  1VQ8 H;  3CCU H;  1YJ9 H;  2ZJP J;  1KQS H;  5GAE N;  4UY8 M;  1YJN H;  3CCE H;  1YHQ H;  5AN9 F;  1KC8 J;  1W2B H;  3PIO J;  3CMA H;  3CC7 H;  5GAD N;  2QEX H;  4WFB J;  4IOC J;  1YIT H;  1JJ2 H;  3OW2 H;  1VQ4 H;  1VQK H;  3J7Z M;  1Q82 J;  3CCR H;  5MLC O;  5DM7 J;  1VQM H;  4U67 J;  4WCE J;  1VQ7 H;  1YIJ H;  1QVG H;  2OTJ H;  3CD6 H;  1Y69 K;  1N8R J;  3PIP J;  2ZJR J;  2QA4 H;  3CC4 H;  4WFA J;  1WKI A;  3CCQ H;  3CPW H;  1VQ9 H;  3CCM H;  3CCL H;  5HL7 J;  1VQN H;  5JVH J;  1QVF H;  3G6E H;  3G71 H;  3CCJ H;  5JVG J;  1NJI J;  1K8A J;  2OTL H;  1YI2 H;  3I55 H;  3CXC H;  4IO9 J;  2ZJQ J;  3DLL J;  3CCV H;  3CC2 H;  1YJW H;  3CCS H;  5GAG N;  1VQL H;  1KD1 J;  5GAH N;  1VQP H;  1M90 J;  3I56 H;  1Q81 J;  1VQO H;  3CME H;  1VQ6 H;  1M1K J;  5H1S O;  1Q7Y J;  1K73 J;  5DM6 J;  4WFN J;  3G4S H;  1VQ5 H; 
#chains in the Genus database with same CATH topology
 4WF9 J;  3CF5 J;  4KWW A;  1K9M J;  1S72 H;  4IOA J;  2PA2 A;  4AP8 A;  4EAF A;  3G4S H;  2I1O A;  3NRZ C;  4C7Y A;  1FM0 E;  2Q5W E;  1N62 B;  4US9 A;  5AYY A;  3PAJ A;  1ZXI B;  1Q86 J;  2OMD A;  3C2R A;  1VQ8 H;  3CCU H;  5HUO A;  4XR5 A;  3ETR C;  4EAD A;  1FMA E;  1YJ9 H;  2ZJP J;  1KQS H;  3C2F A;  5GAE N;  5AYX A;  4UY8 M;  1O4U A;  1NVJ A;  1FO4 A;  3C2O A;  1NVI E;  4YEK A;  1YJN H;  1QPR A;  1VDV A;  3CCE H;  2B7Q A;  4US8 A;  5AN9 F;  1YHQ H;  1KC8 J;  2W55 B;  4GA6 A;  3NS1 C;  4YYY A;  1W2B H;  1WYG A;  3PIO J;  3AN1 A;  3CMA H;  3CC7 H;  3L0G A;  5GAD N;  3FC4 A;  1BRW A;  2W3R B;  2W3S B;  2QEX H;  1N63 B;  4WFB J;  4IOC J;  1YIT H;  1QPO A;  1OTP A;  1V97 A;  3BII E;  2WK5 A;  3WO0 A;  3EUB 4;  1JJ2 H;  1N60 B;  2I14 A;  3OW2 H;  4KWV A;  1VQ4 H;  3L4P A;  1VQK H;  3J7Z M;  3WO1 A;  5AYZ A;  3VMM A;  1YTK A;  5EY3 A;  4I9A A;  1FFU B;  3RPF A;  1Q82 J;  2WP4 A;  5MPO C;  3CCR H;  1QPQ A;  5MLC O;  5DM7 J;  1VQM H;  4U67 J;  3NVY C;  4WCE J;  1VQ7 H;  3FAH A;  1YIJ H;  4C7Z A;  1QVG H;  2OTJ H;  3CD6 H;  4X46 A;  2J0F A;  1Y69 K;  1QAP A;  3AM9 A;  1N8R J;  3C2V A;  3PIP J;  2ZJR J;  2QA4 H;  3CC4 H;  2E3T A;  2QIE A;  1JRO B;  1FFV B;  5HUP A;  1N61 B;  4WFA J;  2TPT A;  4GA4 A;  1WKI A;  2B7N A;  3CCQ H;  3CPW H;  1YTD A;  3H5Q A;  1YTE A;  1VQ9 H;  3CCM H;  3CCL H;  5HL7 J;  1VQN H;  5JVH J;  1QVF H;  1QPN A;  3G6E H;  3G71 H;  3CCJ H;  5JVG J;  1NJI J;  1K8A J;  2OTL H;  2DSJ A;  1UOU A;  1YI2 H;  4C80 A;  4ZOH A;  1N5W B;  3I55 H;  3AMZ A;  5EP8 A;  3CXC H;  1JRP B;  4IO9 J;  3NVW C;  2JBM A;  2ZJQ J;  3DLL J;  3CCV H;  3CC2 H;  1X1O A;  1YJW H;  3CCS H;  5HUL A;  5GAG N;  4GA5 A;  4LHM A;  1VQL H;  1KD1 J;  5GAH N;  2W54 B;  4USA A;  1VQP H;  1DGJ A;  3GNN A;  1VLB A;  1FIQ C;  1M90 J;  3I56 H;  1N5X A;  1AZY A;  3C2E A;  1Q81 J;  1VQO H;  3CME H;  3NVZ C;  2B7P A;  1SIJ A;  2WK6 A;  3SR6 C;  3TQV A;  1VQ6 H;  1RM6 A;  1M1K J;  1SB3 A;  3NVV C;  5H1S O;  1Q7Y J;  1K73 J;  5DM6 J;  3B9J C;  4WFN J;  3WNZ A;  1VQ5 H; 
#chains in the Genus database with same CATH homology
 4WF9 J;  3CF5 J;  1K9M J;  1S72 H;  4IOA J;  2PA2 A;  1Q86 J;  1VQ8 H;  3CCU H;  1YJ9 H;  2ZJP J;  1KQS H;  5GAE N;  4UY8 M;  1YJN H;  3CCE H;  1YHQ H;  5AN9 F;  1KC8 J;  1W2B H;  3PIO J;  3CMA H;  3CC7 H;  5GAD N;  2QEX H;  4WFB J;  4IOC J;  1YIT H;  1JJ2 H;  3OW2 H;  1VQ4 H;  1VQK H;  3J7Z M;  1Q82 J;  3CCR H;  5MLC O;  5DM7 J;  1VQM H;  4U67 J;  4WCE J;  1VQ7 H;  1YIJ H;  1QVG H;  2OTJ H;  3CD6 H;  1Y69 K;  1N8R J;  3PIP J;  2ZJR J;  2QA4 H;  3CC4 H;  4WFA J;  1WKI A;  3CCQ H;  3CPW H;  1VQ9 H;  3CCM H;  3CCL H;  5HL7 J;  1VQN H;  5JVH J;  1QVF H;  3G6E H;  3G71 H;  3CCJ H;  5JVG J;  1NJI J;  1K8A J;  2OTL H;  1YI2 H;  3I55 H;  3CXC H;  4IO9 J;  2ZJQ J;  3DLL J;  3CCV H;  3CC2 H;  1YJW H;  3CCS H;  5GAG N;  1VQL H;  1KD1 J;  5GAH N;  1VQP H;  1M90 J;  3I56 H;  1Q81 J;  1VQO H;  3CME H;  1VQ6 H;  1M1K J;  5H1S O;  1Q7Y J;  1K73 J;  5DM6 J;  4WFN J;  3G4S H;  1VQ5 H; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...