3PIPJ

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
136
structure length
136
Chain Sequence
KRTKFRKQFRGRMTGDAKGGDYVAFGDYGLIAMEPAWIKSNQIEACRIVMSRHFRRGGKIYIRIFPDKPVTKKPAETRMGKGKGAVEYWVSVVKPGRVMFEVAGVTEEQAKEAFRLAGHKLPIQTKMVKREVYDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 18
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
J PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 3pipJ01
1QVGH 4UY8M 1JJ2H 2OTJH 5JVGJ 3G71H 1YIJH 5JVHJ 3CD6H 3CCLH 3CCJH 3DLLJ 1Q81J 1K9MJ 1VQMH 1YI2H 1YJWH 3CCEH 1VQNH 5GAGN 3CCSH 3I55H 5DM6J 1W2BH 4WF9J 1Q86J 4IOCJ 3CC2H 3J7ZM 3CF5J 1VQPH 5AN9F 5GAHN 5DM7J 1Q82J 3G6EH 4WFAJ 1VQ8H 4WFNJ 2QA4H 1VQ6H 1YJNH 1Y69K 5MLCO 3PIOJ 4WFBJ 4U67J 1VQ4H 3CC4H 1QVFH 1WKIA 3CCRH 4IO9J 1KD1J 3CCUH 2PA2A 1VQ7H 1S72H 1VQOH 2ZJPJ 5GADN 1YITH 2QEXH 3CCQH 3OW2H 1NJIJ 3CPWH 1VQLH 3CXCH 5H1SO 1K8AJ 3CCVH 3CC7H 3PIPJ 1YJ9H 1VQ9H 1M1KJ 2OTLH 4WCEJ 3CMEH 3I56H 4IOAJ 5HL7J 2ZJRJ 1Q7YJ 1KC8J 5GAEN 3G4SH 2ZJQJ 1KQSH 1M90J 1YHQH 1N8RJ 1K73J 1VQ5H 1VQKH 3CMAH 3CCMH
chains in the Genus database with same CATH superfamily
1JROB 1QVGH 4UY8M 1JJ2H 1QPQA 1V97A 3C2EA 4USAA 5JVGJ 2OTJH 1N5WB 3G71H 1YIJH 5JVHJ 3CD6H 1FMAE 3CCLH 3CCJH 4LHMA 3DLLJ 1ZXIB 1Q81J 1O4UA 2TPTA 1K9MJ 5EY3A 1VQMH 1YI2H 1YJWH 4C80A 1WYGA 3L4PA 3C2VA 3AN1A 3CCEH 4GA4A 1DGJA 2W54B 3C2RA 1VQNH 2W55B 5GAGN 3CCSH 1AZYA 3I55H 3NVYC 3L0GA 5DM6J 1W2BH 3BIIE 1VLBA 4WF9J 1Q86J 4AP8A 3CC2H 4GA6A 4IOCJ 3NVVC 3SR6C 3J7ZM 2W3SB 4US9A 3CF5J 1VQPH 5AN9F 5GAHN 5DM7J 1Q82J 2WP4A 4KWVA 3G6EH 1N61B 3TQVA 3WO0A 4WFAJ 4WFNJ 2QA4H 1VQ8H 1VQ6H 3FC4A 2I1OA 1YJNH 3NVZC 1NVIE 1BRWA 5MLCO 1Y69K 1FO4A 3FAHA 4WFBJ 3PIOJ 4XR5A 5EP8A 2DSJA 4U67J 1RM6A 1VQ4H 5HUOA 4YYYA 4ZOHA 1SB3A 2B7NA 3CC4H 1FIQC 1OTPA 3WNZA 1X1OA 4US8A 3NS1C 1QVFH 1QAPA 1WKIA 3CCRH 3H5QA 1N60B 3NRZC 4IO9J 1KD1J 1FFVB 2J0FA 3CCUH 2PA2A 1FM0E 3C2FA 1VQ7H 5AYXA 1QPNA 3PAJA 1S72H 2B7PA 4EAFA 3EUB4 1VQOH 1QPRA 1YTDA 2WK6A 2ZJPJ 1N62B 5GADN 4KWWA 1YITH 3VMMA 1YTKA 2QEXH 3CCQH 3OW2H 1NJIJ 3C2OA 1JRPB 3RPFA 3GNNA 1UOUA 2W3RB 5HUPA 1VQLH 3CPWH 3CXCH 4YEKA 5MPOC 5AYZA 5H1SO 1K8AJ 3CCVH 3CC7H 3ETRC 2E3TA 3PIPJ 1YJ9H 1NVJA 1M1KJ 1YTEA 4WCEJ 1VQ9H 3CMEH 2OTLH 3I56H 3B9JC 1FFUB 4IOAJ 2JBMA 2WK5A 5HL7J 2ZJRJ 1QPOA 4EADA 1N63B 1Q7YJ 4GA5A 1KC8J 3NVWC 5HULA 2QIEA 4C7ZA 4X46A 1SIJA 2B7QA 5GAEN 3G4SH 4I9AA 3WO1A 2ZJQJ 1KQSH 1VDVA 4C7YA 2Q5WE 3AMZA 3AM9A 5AYYA 1M90J 1YHQH 1N8RJ 1N5XA 2I14A 1K73J 1VQ5H 1VQKH 3CMAH 3CCMH 2OMDA
chains in the Genus database with same CATH topology
1QVGH 4UY8M 1JJ2H 2OTJH 5JVGJ 3G71H 1YIJH 5JVHJ 3CD6H 3CCLH 3CCJH 3DLLJ 1Q81J 1K9MJ 1VQMH 1YI2H 1YJWH 3CCEH 1VQNH 5GAGN 3CCSH 3I55H 5DM6J 1W2BH 4WF9J 1Q86J 4IOCJ 3CC2H 3J7ZM 3CF5J 1VQPH 5AN9F 5GAHN 5DM7J 1Q82J 3G6EH 4WFAJ 1VQ8H 4WFNJ 2QA4H 1VQ6H 1YJNH 1Y69K 5MLCO 3PIOJ 4WFBJ 4U67J 1VQ4H 3CC4H 1QVFH 1WKIA 3CCRH 4IO9J 1KD1J 3CCUH 2PA2A 1VQ7H 1S72H 1VQOH 2ZJPJ 5GADN 1YITH 2QEXH 3CCQH 3OW2H 1NJIJ 3CPWH 1VQLH 3CXCH 5H1SO 1K8AJ 3CCVH 3CC7H 3PIPJ 1YJ9H 1VQ9H 1M1KJ 2OTLH 4WCEJ 3CMEH 3I56H 4IOAJ 5HL7J 2ZJRJ 1Q7YJ 1KC8J 5GAEN 3G4SH 2ZJQJ 1KQSH 1M90J 1YHQH 1N8RJ 1K73J 1VQ5H 1VQKH 3CMAH 3CCMH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QVG H;  4UY8 M;  1JJ2 H;  2OTJ H;  5JVG J;  3G71 H;  1YIJ H;  5JVH J;  3CD6 H;  3CCL H;  3CCJ H;  3DLL J;  1Q81 J;  1K9M J;  1VQM H;  1YI2 H;  1YJW H;  3CCE H;  1VQN H;  5GAG N;  3CCS H;  3I55 H;  5DM6 J;  1W2B H;  4WF9 J;  1Q86 J;  4IOC J;  3CC2 H;  3J7Z M;  3CF5 J;  1VQP H;  5AN9 F;  5GAH N;  5DM7 J;  1Q82 J;  3G6E H;  4WFA J;  1VQ8 H;  4WFN J;  2QA4 H;  1VQ6 H;  1YJN H;  1Y69 K;  5MLC O;  3PIO J;  4WFB J;  4U67 J;  1VQ4 H;  3CC4 H;  1QVF H;  1WKI A;  3CCR H;  4IO9 J;  1KD1 J;  3CCU H;  2PA2 A;  1VQ7 H;  1S72 H;  1VQO H;  2ZJP J;  5GAD N;  1YIT H;  2QEX H;  3CCQ H;  3OW2 H;  1NJI J;  3CPW H;  1VQL H;  3CXC H;  5H1S O;  1K8A J;  3CCV H;  3CC7 H;  3PIP J;  1YJ9 H;  1VQ9 H;  1M1K J;  2OTL H;  4WCE J;  3CME H;  3I56 H;  4IOA J;  5HL7 J;  2ZJR J;  1Q7Y J;  1KC8 J;  5GAE N;  3G4S H;  2ZJQ J;  1KQS H;  1M90 J;  1YHQ H;  1N8R J;  1K73 J;  1VQ5 H;  1VQK H;  3CMA H;  3CCM H; 
#chains in the Genus database with same CATH topology
 1JRO B;  1QVG H;  4UY8 M;  1JJ2 H;  1QPQ A;  1V97 A;  3C2E A;  4USA A;  5JVG J;  2OTJ H;  1N5W B;  3G71 H;  1YIJ H;  5JVH J;  3CD6 H;  1FMA E;  3CCL H;  3CCJ H;  4LHM A;  3DLL J;  1ZXI B;  1Q81 J;  1O4U A;  2TPT A;  1K9M J;  5EY3 A;  1VQM H;  1YI2 H;  1YJW H;  4C80 A;  1WYG A;  3L4P A;  3C2V A;  3AN1 A;  3CCE H;  4GA4 A;  1DGJ A;  2W54 B;  3C2R A;  1VQN H;  2W55 B;  5GAG N;  3CCS H;  1AZY A;  3I55 H;  3NVY C;  3L0G A;  5DM6 J;  1W2B H;  3BII E;  1VLB A;  4WF9 J;  1Q86 J;  4AP8 A;  3CC2 H;  4GA6 A;  4IOC J;  3NVV C;  3SR6 C;  3J7Z M;  2W3S B;  4US9 A;  3CF5 J;  1VQP H;  5AN9 F;  5GAH N;  5DM7 J;  1Q82 J;  2WP4 A;  4KWV A;  3G6E H;  1N61 B;  3TQV A;  3WO0 A;  4WFA J;  4WFN J;  2QA4 H;  1VQ8 H;  1VQ6 H;  3FC4 A;  2I1O A;  1YJN H;  3NVZ C;  1NVI E;  1BRW A;  5MLC O;  1Y69 K;  1FO4 A;  3FAH A;  4WFB J;  3PIO J;  4XR5 A;  5EP8 A;  2DSJ A;  4U67 J;  1RM6 A;  1VQ4 H;  5HUO A;  4YYY A;  4ZOH A;  1SB3 A;  2B7N A;  3CC4 H;  1FIQ C;  1OTP A;  3WNZ A;  1X1O A;  4US8 A;  3NS1 C;  1QVF H;  1QAP A;  1WKI A;  3CCR H;  3H5Q A;  1N60 B;  3NRZ C;  4IO9 J;  1KD1 J;  1FFV B;  2J0F A;  3CCU H;  2PA2 A;  1FM0 E;  3C2F A;  1VQ7 H;  5AYX A;  1QPN A;  3PAJ A;  1S72 H;  2B7P A;  4EAF A;  3EUB 4;  1VQO H;  1QPR A;  1YTD A;  2WK6 A;  2ZJP J;  1N62 B;  5GAD N;  4KWW A;  1YIT H;  3VMM A;  1YTK A;  2QEX H;  3CCQ H;  3OW2 H;  1NJI J;  3C2O A;  1JRP B;  3RPF A;  3GNN A;  1UOU A;  2W3R B;  5HUP A;  1VQL H;  3CPW H;  3CXC H;  4YEK A;  5MPO C;  5AYZ A;  5H1S O;  1K8A J;  3CCV H;  3CC7 H;  3ETR C;  2E3T A;  3PIP J;  1YJ9 H;  1NVJ A;  1M1K J;  1YTE A;  4WCE J;  1VQ9 H;  3CME H;  2OTL H;  3I56 H;  3B9J C;  1FFU B;  4IOA J;  2JBM A;  2WK5 A;  5HL7 J;  2ZJR J;  1QPO A;  4EAD A;  1N63 B;  1Q7Y J;  4GA5 A;  1KC8 J;  3NVW C;  5HUL A;  2QIE A;  4C7Z A;  4X46 A;  1SIJ A;  2B7Q A;  5GAE N;  3G4S H;  4I9A A;  3WO1 A;  2ZJQ J;  1KQS H;  1VDV A;  4C7Y A;  2Q5W E;  3AMZ A;  3AM9 A;  5AYY A;  1M90 J;  1YHQ H;  1N8R J;  1N5X A;  2I14 A;  1K73 J;  1VQ5 H;  1VQK H;  3CMA H;  3CCM H;  2OMD A; 
#chains in the Genus database with same CATH homology
 1QVG H;  4UY8 M;  1JJ2 H;  2OTJ H;  5JVG J;  3G71 H;  1YIJ H;  5JVH J;  3CD6 H;  3CCL H;  3CCJ H;  3DLL J;  1Q81 J;  1K9M J;  1VQM H;  1YI2 H;  1YJW H;  3CCE H;  1VQN H;  5GAG N;  3CCS H;  3I55 H;  5DM6 J;  1W2B H;  4WF9 J;  1Q86 J;  4IOC J;  3CC2 H;  3J7Z M;  3CF5 J;  1VQP H;  5AN9 F;  5GAH N;  5DM7 J;  1Q82 J;  3G6E H;  4WFA J;  1VQ8 H;  4WFN J;  2QA4 H;  1VQ6 H;  1YJN H;  1Y69 K;  5MLC O;  3PIO J;  4WFB J;  4U67 J;  1VQ4 H;  3CC4 H;  1QVF H;  1WKI A;  3CCR H;  4IO9 J;  1KD1 J;  3CCU H;  2PA2 A;  1VQ7 H;  1S72 H;  1VQO H;  2ZJP J;  5GAD N;  1YIT H;  2QEX H;  3CCQ H;  3OW2 H;  1NJI J;  3CPW H;  1VQL H;  3CXC H;  5H1S O;  1K8A J;  3CCV H;  3CC7 H;  3PIP J;  1YJ9 H;  1VQ9 H;  1M1K J;  2OTL H;  4WCE J;  3CME H;  3I56 H;  4IOA J;  5HL7 J;  2ZJR J;  1Q7Y J;  1KC8 J;  5GAE N;  3G4S H;  2ZJQ J;  1KQS H;  1M90 J;  1YHQ H;  1N8R J;  1K73 J;  1VQ5 H;  1VQK H;  3CMA H;  3CCM H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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