4IO9J

Crystal structure of compound 4d bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
136
structure length
136
Chain Sequence
KRTKFRKQFRGRMTGDAKGGDYVAFGDYGLIAMEPAWIKSNQIEACRIVMSRHFRRGGKIYIRIFPDKPVTKKPAETRMGKGKGAVEYWVSVVKPGRVMFEVAGVTEEQAKEAFRLAGHKLPIQTKMVKREVYDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 22
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
J PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 4io9J01
1QVGH 1VQOH 1K8AJ 1KD1J 1KC8J 1YI2H 1Q86J 3CPWH 5JVGJ 4WCEJ 1VQ8H 1Q7YJ 3CCVH 2QA4H 1YJNH 3CCLH 1Q82J 1N8RJ 4WF9J 5GADN 3CCSH 3OW2H 3G71H 1K9MJ 2ZJRJ 1VQNH 5MLCO 3CC2H 4U67J 1VQMH 5DM7J 3CXCH 3CCRH 1YJWH 3CCQH 3CMEH 1NJIJ 3CMAH 5GAGN 3DLLJ 5H1SO 1K73J 1VQKH 1WKIA 1YITH 5AN9F 2PA2A 2QEXH 3PIOJ 3PIPJ 1M90J 3CCUH 3G4SH 2OTJH 3CC7H 5GAHN 3I56H 2OTLH 1VQ7H 1M1KJ 1W2BH 3CCEH 3I55H 1VQPH 1VQ9H 5DM6J 1KQSH 1YIJH 1YJ9H 4WFNJ 1VQ6H 1QVFH 4IOAJ 4IOCJ 4WFAJ 4IO9J 5GAEN 3CCMH 5HL7J 3CF5J 1JJ2H 3J7ZM 1Q81J 3CCJH 1VQ4H 2ZJPJ 3CD6H 1YHQH 5JVHJ 4UY8M 2ZJQJ 1S72H 3G6EH 1VQLH 3CC4H 4WFBJ 1Y69K 1VQ5H
chains in the Genus database with same CATH superfamily
3C2EA 3WO1A 1QVGH 1VQOH 2W3SB 1K8AJ 2W54B 1KD1J 1QPNA 5EY3A 1KC8J 2B7QA 3WO0A 1BRWA 1YI2H 2B7NA 2DSJA 1Q86J 4YEKA 1N60B 1YTDA 1QPQA 4XR5A 3CPWH 3WNZA 4US8A 4AP8A 5JVGJ 4I9AA 4WCEJ 1VQ8H 1SIJA 1Q7YJ 5HUPA 3TQVA 3CCVH 1O4UA 1NVJA 2QA4H 1YJNH 3CCLH 1Q82J 1N8RJ 2Q5WE 4WF9J 1V97A 3BIIE 2J0FA 3L0GA 5HUOA 3NVVC 2QIEA 5GADN 3NRZC 1VDVA 3CCSH 3OW2H 2W55B 3G71H 3NVZC 3FAHA 1K9MJ 2ZJRJ 2I1OA 4C80A 1VQNH 3NVYC 4GA6A 5MLCO 3ETRC 3SR6C 3CC2H 4U67J 1QPRA 1VQMH 4LHMA 1YTEA 3RPFA 5DM7J 1QPOA 2WK5A 4KWVA 3CXCH 1N61B 3CCRH 1YJWH 3CCQH 1WYGA 1NJIJ 3CMAH 3CMEH 3AMZA 4USAA 1QAPA 2JBMA 5GAGN 1FFVB 3C2RA 3DLLJ 1FFUB 4GA4A 5H1SO 1FO4A 1K73J 1VQKH 4US9A 1WKIA 1FMAE 1YITH 5AN9F 2PA2A 3C2FA 4C7ZA 3C2OA 3PIOJ 1YTKA 1FM0E 3PIPJ 2QEXH 1M90J 3CCUH 3G4SH 2OTJH 3CC7H 1OTPA 1JRPB 1X1OA 3VMMA 5GAHN 3I56H 1NVIE 2WK6A 2WP4A 2B7PA 2OTLH 1VQ7H 1M1KJ 3PAJA 5EP8A 3CCEH 1W2BH 2I14A 4KWWA 3I55H 2OMDA 1VQPH 1VQ9H 1DGJA 4C7YA 4YYYA 5DM6J 1KQSH 3C2VA 1YIJH 1YJ9H 4WFNJ 1VQ6H 1QVFH 4IOAJ 3NS1C 1RM6A 4IOCJ 4WFAJ 1AZYA 4IO9J 5GAEN 1N62B 1SB3A 5HL7J 3CCMH 3CF5J 1JJ2H 3H5QA 3AM9A 3FC4A 3J7ZM 5MPOC 4EADA 1Q81J 1VQ4H 2ZJPJ 1UOUA 2E3TA 3B9JC 3CCJH 3CD6H 4EAFA 1YHQH 4ZOHA 3AN1A 5JVHJ 3EUB4 4UY8M 2ZJQJ 5AYZA 1S72H 1N63B 1N5WB 2TPTA 2W3RB 3G6EH 1VQLH 1VLBA 3NVWC 5AYXA 5HULA 3CC4H 1JROB 4GA5A 4X46A 5AYYA 4WFBJ 1N5XA 3L4PA 1Y69K 1FIQC 1VQ5H 1ZXIB 3GNNA
chains in the Genus database with same CATH topology
1QVGH 1VQOH 1K8AJ 1KD1J 1KC8J 1YI2H 1Q86J 3CPWH 5JVGJ 4WCEJ 1VQ8H 1Q7YJ 3CCVH 2QA4H 1YJNH 3CCLH 1Q82J 1N8RJ 4WF9J 5GADN 3CCSH 3OW2H 3G71H 1K9MJ 2ZJRJ 1VQNH 5MLCO 3CC2H 4U67J 1VQMH 5DM7J 3CXCH 3CCRH 1YJWH 3CCQH 3CMEH 1NJIJ 3CMAH 5GAGN 3DLLJ 5H1SO 1K73J 1VQKH 1WKIA 1YITH 5AN9F 2PA2A 2QEXH 3PIOJ 3PIPJ 1M90J 3CCUH 3G4SH 2OTJH 3CC7H 5GAHN 3I56H 2OTLH 1VQ7H 1M1KJ 1W2BH 3CCEH 3I55H 1VQPH 1VQ9H 5DM6J 1KQSH 1YIJH 1YJ9H 4WFNJ 1VQ6H 1QVFH 4IOAJ 4IOCJ 4WFAJ 4IO9J 5GAEN 3CCMH 5HL7J 3CF5J 1JJ2H 3J7ZM 1Q81J 3CCJH 1VQ4H 2ZJPJ 3CD6H 1YHQH 5JVHJ 4UY8M 2ZJQJ 1S72H 3G6EH 1VQLH 3CC4H 4WFBJ 1Y69K 1VQ5H
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QVG H;  1VQO H;  1K8A J;  1KD1 J;  1KC8 J;  1YI2 H;  1Q86 J;  3CPW H;  5JVG J;  4WCE J;  1VQ8 H;  1Q7Y J;  3CCV H;  2QA4 H;  1YJN H;  3CCL H;  1Q82 J;  1N8R J;  4WF9 J;  5GAD N;  3CCS H;  3OW2 H;  3G71 H;  1K9M J;  2ZJR J;  1VQN H;  5MLC O;  3CC2 H;  4U67 J;  1VQM H;  5DM7 J;  3CXC H;  3CCR H;  1YJW H;  3CCQ H;  3CME H;  1NJI J;  3CMA H;  5GAG N;  3DLL J;  5H1S O;  1K73 J;  1VQK H;  1WKI A;  1YIT H;  5AN9 F;  2PA2 A;  2QEX H;  3PIO J;  3PIP J;  1M90 J;  3CCU H;  3G4S H;  2OTJ H;  3CC7 H;  5GAH N;  3I56 H;  2OTL H;  1VQ7 H;  1M1K J;  1W2B H;  3CCE H;  3I55 H;  1VQP H;  1VQ9 H;  5DM6 J;  1KQS H;  1YIJ H;  1YJ9 H;  4WFN J;  1VQ6 H;  1QVF H;  4IOA J;  4IOC J;  4WFA J;  4IO9 J;  5GAE N;  3CCM H;  5HL7 J;  3CF5 J;  1JJ2 H;  3J7Z M;  1Q81 J;  3CCJ H;  1VQ4 H;  2ZJP J;  3CD6 H;  1YHQ H;  5JVH J;  4UY8 M;  2ZJQ J;  1S72 H;  3G6E H;  1VQL H;  3CC4 H;  4WFB J;  1Y69 K;  1VQ5 H; 
#chains in the Genus database with same CATH topology
 3C2E A;  3WO1 A;  1QVG H;  1VQO H;  2W3S B;  1K8A J;  2W54 B;  1KD1 J;  1QPN A;  5EY3 A;  1KC8 J;  2B7Q A;  3WO0 A;  1BRW A;  1YI2 H;  2B7N A;  2DSJ A;  1Q86 J;  4YEK A;  1N60 B;  1YTD A;  1QPQ A;  4XR5 A;  3CPW H;  3WNZ A;  4US8 A;  4AP8 A;  5JVG J;  4I9A A;  4WCE J;  1VQ8 H;  1SIJ A;  1Q7Y J;  5HUP A;  3TQV A;  3CCV H;  1O4U A;  1NVJ A;  2QA4 H;  1YJN H;  3CCL H;  1Q82 J;  1N8R J;  2Q5W E;  4WF9 J;  1V97 A;  3BII E;  2J0F A;  3L0G A;  5HUO A;  3NVV C;  2QIE A;  5GAD N;  3NRZ C;  1VDV A;  3CCS H;  3OW2 H;  2W55 B;  3G71 H;  3NVZ C;  3FAH A;  1K9M J;  2ZJR J;  2I1O A;  4C80 A;  1VQN H;  3NVY C;  4GA6 A;  5MLC O;  3ETR C;  3SR6 C;  3CC2 H;  4U67 J;  1QPR A;  1VQM H;  4LHM A;  1YTE A;  3RPF A;  5DM7 J;  1QPO A;  2WK5 A;  4KWV A;  3CXC H;  1N61 B;  3CCR H;  1YJW H;  3CCQ H;  1WYG A;  1NJI J;  3CMA H;  3CME H;  3AMZ A;  4USA A;  1QAP A;  2JBM A;  5GAG N;  1FFV B;  3C2R A;  3DLL J;  1FFU B;  4GA4 A;  5H1S O;  1FO4 A;  1K73 J;  1VQK H;  4US9 A;  1WKI A;  1FMA E;  1YIT H;  5AN9 F;  2PA2 A;  3C2F A;  4C7Z A;  3C2O A;  3PIO J;  1YTK A;  1FM0 E;  3PIP J;  2QEX H;  1M90 J;  3CCU H;  3G4S H;  2OTJ H;  3CC7 H;  1OTP A;  1JRP B;  1X1O A;  3VMM A;  5GAH N;  3I56 H;  1NVI E;  2WK6 A;  2WP4 A;  2B7P A;  2OTL H;  1VQ7 H;  1M1K J;  3PAJ A;  5EP8 A;  3CCE H;  1W2B H;  2I14 A;  4KWW A;  3I55 H;  2OMD A;  1VQP H;  1VQ9 H;  1DGJ A;  4C7Y A;  4YYY A;  5DM6 J;  1KQS H;  3C2V A;  1YIJ H;  1YJ9 H;  4WFN J;  1VQ6 H;  1QVF H;  4IOA J;  3NS1 C;  1RM6 A;  4IOC J;  4WFA J;  1AZY A;  4IO9 J;  5GAE N;  1N62 B;  1SB3 A;  5HL7 J;  3CCM H;  3CF5 J;  1JJ2 H;  3H5Q A;  3AM9 A;  3FC4 A;  3J7Z M;  5MPO C;  4EAD A;  1Q81 J;  1VQ4 H;  2ZJP J;  1UOU A;  2E3T A;  3B9J C;  3CCJ H;  3CD6 H;  4EAF A;  1YHQ H;  4ZOH A;  3AN1 A;  5JVH J;  3EUB 4;  4UY8 M;  2ZJQ J;  5AYZ A;  1S72 H;  1N63 B;  1N5W B;  2TPT A;  2W3R B;  3G6E H;  1VQL H;  1VLB A;  3NVW C;  5AYX A;  5HUL A;  3CC4 H;  1JRO B;  4GA5 A;  4X46 A;  5AYY A;  4WFB J;  1N5X A;  3L4P A;  1Y69 K;  1FIQ C;  1VQ5 H;  1ZXI B;  3GNN A; 
#chains in the Genus database with same CATH homology
 1QVG H;  1VQO H;  1K8A J;  1KD1 J;  1KC8 J;  1YI2 H;  1Q86 J;  3CPW H;  5JVG J;  4WCE J;  1VQ8 H;  1Q7Y J;  3CCV H;  2QA4 H;  1YJN H;  3CCL H;  1Q82 J;  1N8R J;  4WF9 J;  5GAD N;  3CCS H;  3OW2 H;  3G71 H;  1K9M J;  2ZJR J;  1VQN H;  5MLC O;  3CC2 H;  4U67 J;  1VQM H;  5DM7 J;  3CXC H;  3CCR H;  1YJW H;  3CCQ H;  3CME H;  1NJI J;  3CMA H;  5GAG N;  3DLL J;  5H1S O;  1K73 J;  1VQK H;  1WKI A;  1YIT H;  5AN9 F;  2PA2 A;  2QEX H;  3PIO J;  3PIP J;  1M90 J;  3CCU H;  3G4S H;  2OTJ H;  3CC7 H;  5GAH N;  3I56 H;  2OTL H;  1VQ7 H;  1M1K J;  1W2B H;  3CCE H;  3I55 H;  1VQP H;  1VQ9 H;  5DM6 J;  1KQS H;  1YIJ H;  1YJ9 H;  4WFN J;  1VQ6 H;  1QVF H;  4IOA J;  4IOC J;  4WFA J;  4IO9 J;  5GAE N;  3CCM H;  5HL7 J;  3CF5 J;  1JJ2 H;  3J7Z M;  1Q81 J;  3CCJ H;  1VQ4 H;  2ZJP J;  3CD6 H;  1YHQ H;  5JVH J;  4UY8 M;  2ZJQ J;  1S72 H;  3G6E H;  1VQL H;  3CC4 H;  4WFB J;  1Y69 K;  1VQ5 H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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