4IOCJ

Crystal structure of compound 4f bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
136
structure length
136
Chain Sequence
KRTKFRKQFRGRMTGDAKGGDYVAFGDYGLIAMEPAWIKSNQIEACRIVMSRHFRRGGKIYIRIFPDKPVTKKPAETRMGKGKGAVEYWVSVVKPGRVMFEVAGVTEEQAKEAFRLAGHKLPIQTKMVKREVYDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 22
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
J PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 4iocJ01
3OW2H 1K73J 3CF5J 1VQPH 1NJIJ 1VQOH 1KQSH 5JVGJ 5GAEN 1YIJH 3CCRH 1S72H 2QEXH 1KC8J 1VQ9H 2ZJQJ 1YI2H 1VQLH 1K9MJ 3CC7H 3CCJH 2OTJH 1M1KJ 5MLCO 3CCSH 3G71H 5AN9F 4WFAJ 3CC2H 1VQ8H 4WF9J 5DM6J 4U67J 1YJWH 5H1SO 3PIPJ 2OTLH 1Q7YJ 3G6EH 4IOCJ 4IO9J 1VQMH 3CXCH 4WFNJ 3I56H 1YJ9H 1Y69K 3CCEH 4WCEJ 1K8AJ 1WKIA 3CCUH 3I55H 1Q86J 1W2BH 3J7ZM 4WFBJ 1Q82J 2ZJPJ 1YJNH 5JVHJ 2ZJRJ 1VQ4H 1VQNH 1JJ2H 1VQKH 2QA4H 1Q81J 1YHQH 3G4SH 2PA2A 1VQ7H 5DM7J 3CCQH 3DLLJ 5HL7J 5GAHN 3CCLH 1YITH 5GAGN 5GADN 3CCVH 4IOAJ 3CMAH 1VQ6H 3CC4H 1VQ5H 1M90J 3PIOJ 4UY8M 1QVGH 3CD6H 1QVFH 3CMEH 1N8RJ 1KD1J 3CCMH 3CPWH
chains in the Genus database with same CATH superfamily
3OW2H 2B7PA 1K73J 2J0FA 3SR6C 3CF5J 3C2FA 2JBMA 1VQPH 1NVIE 1NJIJ 1VQOH 3NVVC 4EADA 1QPRA 1KQSH 5JVGJ 4C7YA 1FM0E 3AMZA 2OMDA 5GAEN 1FMAE 1YIJH 3CCRH 1S72H 2W55B 2QEXH 1KC8J 1V97A 4YEKA 3NVZC 3L0GA 1FO4A 5HUOA 1VQ9H 2ZJQJ 1SB3A 4C7ZA 4I9AA 1YI2H 5EY3A 1VQLH 1K9MJ 2B7QA 3CC7H 3FAHA 1QPOA 1VLBA 3CCJH 4C80A 4AP8A 2OTJH 1QPNA 5MLCO 1M1KJ 4US9A 3CCSH 3RPFA 4GA5A 5AN9F 3G71H 1N5WB 3L4PA 1YTDA 1YTKA 4KWWA 4WFAJ 1N62B 3TQVA 3EUB4 3CC2H 5AYYA 1JRPB 1FFUB 2WK5A 1VQ8H 4WF9J 3VMMA 5DM6J 4KWVA 5HUPA 4EAFA 4U67J 1RM6A 1YJWH 2I1OA 4XR5A 5H1SO 3PIPJ 2DSJA 2OTLH 1Q7YJ 3G6EH 5HULA 4IOCJ 4IO9J 5AYXA 3GNNA 1QPQA 3PAJA 5AYZA 1X1OA 2B7NA 1VQMH 3CXCH 3FC4A 4WFNJ 3I56H 1YJ9H 2I14A 1BRWA 1Y69K 1FFVB 5EP8A 3CCEH 2WK6A 3NS1C 4WCEJ 1OTPA 1K8AJ 2QIEA 1N61B 2TPTA 1FIQC 1JROB 2WP4A 1WKIA 3C2VA 3CCUH 3I55H 1Q86J 3WO1A 1UOUA 2W54B 3WNZA 1W2BH 4ZOHA 3C2OA 3J7ZM 3BIIE 4USAA 4WFBJ 1Q82J 1N60B 2ZJPJ 4GA4A 1YJNH 1YTEA 5JVHJ 1N63B 1VDVA 2ZJRJ 4YYYA 3WO0A 4LHMA 3C2EA 1NVJA 3AM9A 3C2RA 1DGJA 1QAPA 2E3TA 2W3SB 3ETRC 5MPOC 1VQ4H 1VQNH 1JJ2H 1VQKH 3NVYC 1O4UA 1ZXIB 2QA4H 1Q81J 1YHQH 2Q5WE 1WYGA 4US8A 3G4SH 3NVWC 2PA2A 1VQ7H 5DM7J 4X46A 3CCQH 3DLLJ 5HL7J 5GAHN 3CCLH 1YITH 5GAGN 3H5QA 5GADN 3B9JC 3CCVH 4IOAJ 3CMAH 1VQ6H 3AN1A 2W3RB 3CC4H 1VQ5H 1N5XA 4GA6A 1M90J 3PIOJ 4UY8M 1KD1J 1QVGH 3CD6H 1QVFH 3NRZC 3CMEH 1AZYA 1N8RJ 1SIJA 3CCMH 3CPWH
chains in the Genus database with same CATH topology
3OW2H 1K73J 3CF5J 1VQPH 1NJIJ 1VQOH 1KQSH 5JVGJ 5GAEN 1YIJH 3CCRH 1S72H 2QEXH 1KC8J 1VQ9H 2ZJQJ 1YI2H 1VQLH 1K9MJ 3CC7H 3CCJH 2OTJH 1M1KJ 5MLCO 3CCSH 3G71H 5AN9F 4WFAJ 3CC2H 1VQ8H 4WF9J 5DM6J 4U67J 1YJWH 5H1SO 3PIPJ 2OTLH 1Q7YJ 3G6EH 4IOCJ 4IO9J 1VQMH 3CXCH 4WFNJ 3I56H 1YJ9H 1Y69K 3CCEH 4WCEJ 1K8AJ 1WKIA 3CCUH 3I55H 1Q86J 1W2BH 3J7ZM 4WFBJ 1Q82J 2ZJPJ 1YJNH 5JVHJ 2ZJRJ 1VQ4H 1VQNH 1JJ2H 1VQKH 2QA4H 1Q81J 1YHQH 3G4SH 2PA2A 1VQ7H 5DM7J 3CCQH 3DLLJ 5HL7J 5GAHN 3CCLH 1YITH 5GAGN 5GADN 3CCVH 4IOAJ 3CMAH 1VQ6H 3CC4H 1VQ5H 1M90J 3PIOJ 4UY8M 1QVGH 3CD6H 1QVFH 3CMEH 1N8RJ 1KD1J 3CCMH 3CPWH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OW2 H;  1K73 J;  3CF5 J;  1VQP H;  1NJI J;  1VQO H;  1KQS H;  5JVG J;  5GAE N;  1YIJ H;  3CCR H;  1S72 H;  2QEX H;  1KC8 J;  1VQ9 H;  2ZJQ J;  1YI2 H;  1VQL H;  1K9M J;  3CC7 H;  3CCJ H;  2OTJ H;  1M1K J;  5MLC O;  3CCS H;  3G71 H;  5AN9 F;  4WFA J;  3CC2 H;  1VQ8 H;  4WF9 J;  5DM6 J;  4U67 J;  1YJW H;  5H1S O;  3PIP J;  2OTL H;  1Q7Y J;  3G6E H;  4IOC J;  4IO9 J;  1VQM H;  3CXC H;  4WFN J;  3I56 H;  1YJ9 H;  1Y69 K;  3CCE H;  4WCE J;  1K8A J;  1WKI A;  3CCU H;  3I55 H;  1Q86 J;  1W2B H;  3J7Z M;  4WFB J;  1Q82 J;  2ZJP J;  1YJN H;  5JVH J;  2ZJR J;  1VQ4 H;  1VQN H;  1JJ2 H;  1VQK H;  2QA4 H;  1Q81 J;  1YHQ H;  3G4S H;  2PA2 A;  1VQ7 H;  5DM7 J;  3CCQ H;  3DLL J;  5HL7 J;  5GAH N;  3CCL H;  1YIT H;  5GAG N;  5GAD N;  3CCV H;  4IOA J;  3CMA H;  1VQ6 H;  3CC4 H;  1VQ5 H;  1M90 J;  3PIO J;  4UY8 M;  1QVG H;  3CD6 H;  1QVF H;  3CME H;  1N8R J;  1KD1 J;  3CCM H;  3CPW H; 
#chains in the Genus database with same CATH topology
 3OW2 H;  2B7P A;  1K73 J;  2J0F A;  3SR6 C;  3CF5 J;  3C2F A;  2JBM A;  1VQP H;  1NVI E;  1NJI J;  1VQO H;  3NVV C;  4EAD A;  1QPR A;  1KQS H;  5JVG J;  4C7Y A;  1FM0 E;  3AMZ A;  2OMD A;  5GAE N;  1FMA E;  1YIJ H;  3CCR H;  1S72 H;  2W55 B;  2QEX H;  1KC8 J;  1V97 A;  4YEK A;  3NVZ C;  3L0G A;  1FO4 A;  5HUO A;  1VQ9 H;  2ZJQ J;  1SB3 A;  4C7Z A;  4I9A A;  1YI2 H;  5EY3 A;  1VQL H;  1K9M J;  2B7Q A;  3CC7 H;  3FAH A;  1QPO A;  1VLB A;  3CCJ H;  4C80 A;  4AP8 A;  2OTJ H;  1QPN A;  5MLC O;  1M1K J;  4US9 A;  3CCS H;  3RPF A;  4GA5 A;  5AN9 F;  3G71 H;  1N5W B;  3L4P A;  1YTD A;  1YTK A;  4KWW A;  4WFA J;  1N62 B;  3TQV A;  3EUB 4;  3CC2 H;  5AYY A;  1JRP B;  1FFU B;  2WK5 A;  1VQ8 H;  4WF9 J;  3VMM A;  5DM6 J;  4KWV A;  5HUP A;  4EAF A;  4U67 J;  1RM6 A;  1YJW H;  2I1O A;  4XR5 A;  5H1S O;  3PIP J;  2DSJ A;  2OTL H;  1Q7Y J;  3G6E H;  5HUL A;  4IOC J;  4IO9 J;  5AYX A;  3GNN A;  1QPQ A;  3PAJ A;  5AYZ A;  1X1O A;  2B7N A;  1VQM H;  3CXC H;  3FC4 A;  4WFN J;  3I56 H;  1YJ9 H;  2I14 A;  1BRW A;  1Y69 K;  1FFV B;  5EP8 A;  3CCE H;  2WK6 A;  3NS1 C;  4WCE J;  1OTP A;  1K8A J;  2QIE A;  1N61 B;  2TPT A;  1FIQ C;  1JRO B;  2WP4 A;  1WKI A;  3C2V A;  3CCU H;  3I55 H;  1Q86 J;  3WO1 A;  1UOU A;  2W54 B;  3WNZ A;  1W2B H;  4ZOH A;  3C2O A;  3J7Z M;  3BII E;  4USA A;  4WFB J;  1Q82 J;  1N60 B;  2ZJP J;  4GA4 A;  1YJN H;  1YTE A;  5JVH J;  1N63 B;  1VDV A;  2ZJR J;  4YYY A;  3WO0 A;  4LHM A;  3C2E A;  1NVJ A;  3AM9 A;  3C2R A;  1DGJ A;  1QAP A;  2E3T A;  2W3S B;  3ETR C;  5MPO C;  1VQ4 H;  1VQN H;  1JJ2 H;  1VQK H;  3NVY C;  1O4U A;  1ZXI B;  2QA4 H;  1Q81 J;  1YHQ H;  2Q5W E;  1WYG A;  4US8 A;  3G4S H;  3NVW C;  2PA2 A;  1VQ7 H;  5DM7 J;  4X46 A;  3CCQ H;  3DLL J;  5HL7 J;  5GAH N;  3CCL H;  1YIT H;  5GAG N;  3H5Q A;  5GAD N;  3B9J C;  3CCV H;  4IOA J;  3CMA H;  1VQ6 H;  3AN1 A;  2W3R B;  3CC4 H;  1VQ5 H;  1N5X A;  4GA6 A;  1M90 J;  3PIO J;  4UY8 M;  1KD1 J;  1QVG H;  3CD6 H;  1QVF H;  3NRZ C;  3CME H;  1AZY A;  1N8R J;  1SIJ A;  3CCM H;  3CPW H; 
#chains in the Genus database with same CATH homology
 3OW2 H;  1K73 J;  3CF5 J;  1VQP H;  1NJI J;  1VQO H;  1KQS H;  5JVG J;  5GAE N;  1YIJ H;  3CCR H;  1S72 H;  2QEX H;  1KC8 J;  1VQ9 H;  2ZJQ J;  1YI2 H;  1VQL H;  1K9M J;  3CC7 H;  3CCJ H;  2OTJ H;  1M1K J;  5MLC O;  3CCS H;  3G71 H;  5AN9 F;  4WFA J;  3CC2 H;  1VQ8 H;  4WF9 J;  5DM6 J;  4U67 J;  1YJW H;  5H1S O;  3PIP J;  2OTL H;  1Q7Y J;  3G6E H;  4IOC J;  4IO9 J;  1VQM H;  3CXC H;  4WFN J;  3I56 H;  1YJ9 H;  1Y69 K;  3CCE H;  4WCE J;  1K8A J;  1WKI A;  3CCU H;  3I55 H;  1Q86 J;  1W2B H;  3J7Z M;  4WFB J;  1Q82 J;  2ZJP J;  1YJN H;  5JVH J;  2ZJR J;  1VQ4 H;  1VQN H;  1JJ2 H;  1VQK H;  2QA4 H;  1Q81 J;  1YHQ H;  3G4S H;  2PA2 A;  1VQ7 H;  5DM7 J;  3CCQ H;  3DLL J;  5HL7 J;  5GAH N;  3CCL H;  1YIT H;  5GAG N;  5GAD N;  3CCV H;  4IOA J;  3CMA H;  1VQ6 H;  3CC4 H;  1VQ5 H;  1M90 J;  3PIO J;  4UY8 M;  1QVG H;  3CD6 H;  1QVF H;  3CME H;  1N8R J;  1KD1 J;  3CCM H;  3CPW H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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