4O1LA

Human adenosine kinase in complex with inhibitor
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
328
structure length
326
Chain Sequence
LRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIII
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Adenosine kinase
total genus 114
structure length 326
sequence length 328
chains with identical sequence B
ec nomenclature ec 2.7.1.20: Adenosine kinase.
pdb deposition date 2013-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00294 PfkB pfkB family carbohydrate kinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1110.10 Alpha Beta 2-Layer Sandwich Adenosine kinase, small domain Adenosine kinase, small domain 4o1lA02
3.40.1190.20 Alpha Beta 3-Layer(aba) Sandwich UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase 4o1lA01
1VK4A 3UQEA 4EUMA 3UQDA 2VARA 3UMOA 2I6AA 4E84A 3LJSA 5EYNA 3W4SA 3NCAA 3K5WA 1LIJA 4YWRA 4C5KA 3GBUA 1ESJA 3RPHA 1ESQA 4XDAA 1TD2A 3H49A 3JULA 3RRBA 3RTBA 4LC4A 2JG5A 3KZHA 3LHXA 2DDOA 4E8ZA 2AA0A 3RT9A 2NWHA 2JG1A 3PZSA 3RREA 1EKKA 2AFBA 2YXUA 3BGKA 3KTNA 3NBWA 4S1MA 2AX3A 1V1AA 5COJA 5EY7A 2HLZA 4C5MA 1GQTA 3RSFA 1LHPA 4KALA 5TQIA 5C40A 5CGAA 3PL2A 3UBOA 4E69A 2A9ZA 1UA4A 1L2LA 1BX4A 4B8SA 4DU5A 4S1IB 3HPDA 2HQQA 4S1HA 1RFTA 2V78A 3RM5A 3K9EA 3OTXA 3RSQA 3IKHA 4K8CA 3QAIA 2YXTA 3RU2A 2QCVA 4KADA 3RQXA 3LKIA 1RFVA 1U2XA 4JJPA 3RTEA 5C3YA 2Q5RA 1DGMA 3RT7A 3RTDA 3B1NA 1YHJA 3IQ0A 3B1QA 4XF6A 4XF7A 3RY7A 3FHXA 4UBEA 3HYOA 3RTGA 2C49A 4KBEA 1RK2A 1VM7A 3RQHA 4N08A 3RRFA 4S1IA 3B1RA 3UQ6A 3NC9A 3NC2A 2AJRA 2XTBA 1GC5A 1LIOA 3BF5A 1VI9A 1YGJA 3RSSA 5F11A 3IE7A 3CQDA 4GM6A 2F7KA 2A9YA 1KYHA 3NBVA 4K9IA 1RKDA 3NL2A 4WJMA 3UQ9A 2HW1A 3MBJA 1JXHA 2PKMA 3DZVA 3RQ5A 3RS8A 4EOHA 1TYYA 1LIKA 4C5LA 2QHPA 2RBCA 4K8TA 4PVVA 1C3QA 2ABSA 1TZ3A 1LIIA 2I6BA 4K8PA 5BYEA 3Q1YA 3HICA 4E8WA 2AJPA 3QA2A 4O1LA 4K9CA 3IBQA 5BYDA 1RFUA 2C4EA 5CGEA 5C3ZA 3FHYA 4B8RA 1V1SA 4K93A 2DCNA 3NM1A 3ZS7A 3RO4A 4DC3A 5C41A 5B6AA 4C5NA 4E8YA 2F02A 3B1OA 2AB8A 3GO7A 3MBHA 5CM5A 5TRWA 3KEUA 1UB0A 4E3AA 5BYCA 2DDWA 1RKSA 3GO6A 3RTCA 2JGVA 3B3LA 3DRWA 3RU3A 4EBUA 3LOOA 3Q92A 2AWDA 1TZ6A 3RQ8A 3RRJA 1JXIA 1V1BA 3N1CA 4U7XA 3RQ2A 3RQ6A 3KD6A 1V19A 1YGKA 3B1PA 2PKKA 3NL5A 4LCAA 3RPZA 3UMPA 4N09A 3NL6A 3VAQA 1WYEA 5BYFA 4EN4A 3RTAA 4C5JA 3IN1A 4JKSA 4KANA 3NL3A 5F0ZA 2ABQA 4XCKA 3RSGA 4LBGA 3IH0A 3RQQA 2DDMA 4O1GA 2FV7A 4YL5A 3VASA 2PKFA 3NM3A 1EKQA 4K8KA 4LBXA 4X8FA 2R3EA 1RKAA 2I5BA 2R3BA 2PKNA 3EWMA 3H74A 3RS9A 4KAHA 3I3YA 1LHRA 4JKUA
chains in the Genus database with same CATH superfamily
4CVLA 3UQEA 3W4SA 3NCAA 3K5WA 3ZM6A 4C5KA 3GBUA 3RPHA 3H49A 3RTBA 4LC4A 2JG5A 5A5FA 3LHXA 2DDOA 2JG1A 3BGKA 4S1MA 2AX3A 4HV4A 3RSFA 3QCZA 5CGAA 3PL2A 1L2LA 1BX4A 4B8SA 3RM5A 3K9EA 4K8CA 3QAIA 2YXTA 2QCVA 3RTEA 2Y66A 1YHJA 3B1QA 4XF6A 4C12A 4KBEA 3RRFA 1GC5A 3RSSA 1KYHA 1P31A 3ZM5A 5A5EA 2AM2A 2QHPA 4K8TA 3HJ6A 1C3QA 2ABSA 3HICA 4O1LA 4QF5A 2C4EA 5CGEA 5C3ZA 1W7KA 3ZS7A 4C5NA 1JBVA 1EEHA 3HN7A 2AWDA 2F00A 3RQ8A 1UAGA 1JXIA 3N1CA 4U7XA 3RQ2A 3RPZA 1WYEA 4EN4A 3RTAA 5F0ZA 3RSGA 4LBGA 1W78A 3VASA 1EKQA 4CVMA 2R3BA 2PKNA 3EWMA 4EUMA 3UQDA 4E84A 1LIJA 4YWRA 1ESJA 1TD2A 3RRBA 2UUOA 4E8ZA 3RT9A 2NWHA 3PZSA 1E0DA 2AFBA 2YXUA 3KTNA 3NBWA 5EY7A 1LHPA 4KALA 4C13A 2A9ZA 4DU5A 4CVKA 3OTXA 4KADA 1RFVA 4JJPA 1DGMA 3RT7A 3B1NA 4XF7A 1FGSA 3RY7A 3FHXA 2AM1A 1VM7A 3RQHA 3B1RA 3UQ6A 3NC9A 1VI9A 3IE7A 3CQDA 2UAGA 2F7KA 4QDIA 3UAGA 4WJMA 3UQ9A 2HW1A 3MBJA 2GCAA 1TYYA 1LIKA 2RBCA 1TZ3A 1LIIA 5BYEA 2Y68A 3ZL8A 1RFUA 2VORA 3FHYA 1V1SA 4K93A 3NM1A 2VTDA 4E8YA 2F02A 3B1OA 3GO7A 3NRSA 5CM5A 3KEUA 5BYCA 2DDWA 3GO6A 3DRWA 3B3LA 4EBUA 1TZ6A 3RQ6A 1V19A 4LCAA 4N09A 3VAQA 3IN1A 2JFFA 3NL3A 1P3DA 2DDMA 4LBXA 3H74A 3I3YA 2VARA 3UMOA 5EYNA 1ESQA 3JULA 2VTEA 3KZHA 4BUCA 2AA0A 1EKKA 1V1AA 2HLZA 4C5MA 1GQTA 1JBWA 5TQIA 3UBOA 4E69A 1UA4A 2X5OA 4S1HA 2HQQA 1RFTA 2V78A 3RU2A 3RQXA 3IQ0A 3HYOA 3RTGA 2C49A 3NC2A 2AJRA 2XTBA 1LIOA 2GC6A 2Y1OA 1YGJA 5F11A 2A9YA 3NBVA 1RKDA 3NL2A 3DZVA 3EAGA 4E8WA 2AJPA 4UAGA 5BYDA 4K9CA 4B8RA 3RO4A 5B6AA 5TRWA 3MBHA 1UB0A 1RKSA 2XJAA 3RTCA 2JGVA 3RU3A 3N2AA 3Q92A 3RRJA 3KD6A 1YGKA 3B1PA 2PKKA 3UMPA 3NL6A 2WTZA 4JKSA 2ABQA 4XCKA 2GCBA 3RQQA 4O1GA 2FV7A 2PKFA 3NM3A 4K8KA 4X8FA 2I5BA 1VK4A 2I6AA 3LJSA 4XDAA 3RREA 2XPCA 2Y67A 5COJA 5C40A 4S1IB 3HPDA 1GQYA 3RSQA 3IKHA 1J6UA 5C3YA 3LKIA 1U2XA 2Q5RA 2GC5A 3RTDA 4UBEA 1RK2A 4N08A 4S1IA 3PYZA 3BF5A 2JFGA 4GM6A 4K9IA 1JXHA 2PKMA 3RQ5A 3RS8A 4EOHA 4C5LA 1GQQA 4PVVA 4K8PA 2I6BA 3Q1YA 3QA2A 3IBQA 2WJPA 3LK7A 5C41A 2DCNA 4DC3A 1GG4A 2AB8A 4E3AA 3LOOA 2UUPA 1E8CA 2VOSA 1V1BA 4BUBA 4ZIYA 2JFHA 1O5ZA 3NL5A 5BYFA 4C5JA 4KANA 3IH0A 4YL5A 2R3EA 1RKAA 3RS9A 4KAHA 1LHRA 4JKUA
chains in the Genus database with same CATH topology
1VK4A 3UQEA 4EUMA 3UQDA 2VARA 3UMOA 2I6AA 4E84A 3LJSA 5EYNA 3W4SA 3NCAA 3K5WA 1LIJA 4YWRA 4C5KA 3GBUA 1ESJA 3RPHA 1ESQA 4XDAA 1TD2A 3H49A 3JULA 3RRBA 3RTBA 4LC4A 2JG5A 3KZHA 3LHXA 2DDOA 4E8ZA 2AA0A 3RT9A 2NWHA 2JG1A 3PZSA 3RREA 1EKKA 2AFBA 2YXUA 3BGKA 3KTNA 3NBWA 4S1MA 2AX3A 1V1AA 5COJA 5EY7A 2HLZA 4C5MA 1GQTA 3RSFA 1LHPA 4KALA 5TQIA 5C40A 5CGAA 3PL2A 3UBOA 4E69A 2A9ZA 1UA4A 1L2LA 1BX4A 4B8SA 4DU5A 4S1IB 3HPDA 2HQQA 4S1HA 1RFTA 2V78A 3RM5A 3K9EA 3OTXA 3RSQA 3IKHA 4K8CA 3QAIA 2YXTA 3RU2A 2QCVA 4KADA 3RQXA 3LKIA 1U2XA 1RFVA 4JJPA 3RTEA 5C3YA 2Q5RA 1DGMA 3RT7A 3RTDA 3B1NA 1YHJA 3IQ0A 3B1QA 4XF6A 4XF7A 3RY7A 3FHXA 4UBEA 3HYOA 3RTGA 2C49A 4KBEA 1RK2A 1VM7A 3RQHA 4N08A 3RRFA 4S1IA 3B1RA 3UQ6A 3NC9A 3NC2A 2AJRA 2XTBA 1GC5A 1LIOA 3BF5A 1VI9A 1YGJA 3RSSA 5F11A 3IE7A 3CQDA 4GM6A 2F7KA 2A9YA 1KYHA 3NBVA 4K9IA 1RKDA 3NL2A 4WJMA 3UQ9A 2HW1A 3MBJA 1JXHA 2PKMA 3DZVA 3RQ5A 3RS8A 4EOHA 1TYYA 1LIKA 4C5LA 2QHPA 2RBCA 4K8TA 4PVVA 3HJ6A 1C3QA 2ABSA 1TZ3A 1LIIA 2I6BA 4K8PA 5BYEA 3Q1YA 3HICA 4E8WA 2AJPA 3QA2A 4O1LA 4K9CA 3IBQA 5BYDA 1RFUA 2C4EA 5CGEA 5C3ZA 3FHYA 4B8RA 1V1SA 4K93A 2DCNA 3NM1A 3ZS7A 3RO4A 4DC3A 5C41A 5B6AA 4C5NA 4E8YA 2F02A 3B1OA 2AB8A 3GO7A 3MBHA 5CM5A 5TRWA 3KEUA 1UB0A 4E3AA 5BYCA 2DDWA 1RKSA 3GO6A 3RTCA 3DRWA 2JGVA 3B3LA 3RU3A 4EBUA 3LOOA 3Q92A 2AWDA 1TZ6A 3RQ8A 3RRJA 1JXIA 1V1BA 3N1CA 4U7XA 3RQ2A 3RQ6A 3KD6A 1V19A 1YGKA 3B1PA 2PKKA 3NL5A 4LCAA 3RPZA 3UMPA 4N09A 3NL6A 3VAQA 1WYEA 5BYFA 4EN4A 3RTAA 4C5JA 3IN1A 4JKSA 4KANA 3NL3A 5F0ZA 2ABQA 4XCKA 3RSGA 4LBGA 3IH0A 3RQQA 2DDMA 4O1GA 2FV7A 4YL5A 3VASA 2PKFA 3NM3A 1EKQA 4K8KA 4LBXA 4X8FA 2R3EA 1RKAA 2I5BA 2R3BA 2PKNA 3EWMA 3H74A 3RS9A 4KAHA 3I3YA 1LHRA 4JKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VK4 A;  3UQE A;  4EUM A;  3UQD A;  2VAR A;  3UMO A;  2I6A A;  4E84 A;  3LJS A;  5EYN A;  3W4S A;  3NCA A;  3K5W A;  1LIJ A;  4YWR A;  4C5K A;  3GBU A;  1ESJ A;  3RPH A;  1ESQ A;  4XDA A;  1TD2 A;  3H49 A;  3JUL A;  3RRB A;  3RTB A;  4LC4 A;  2JG5 A;  3KZH A;  3LHX A;  2DDO A;  4E8Z A;  2AA0 A;  3RT9 A;  2NWH A;  2JG1 A;  3PZS A;  3RRE A;  1EKK A;  2AFB A;  2YXU A;  3BGK A;  3KTN A;  3NBW A;  4S1M A;  2AX3 A;  1V1A A;  5COJ A;  5EY7 A;  2HLZ A;  4C5M A;  1GQT A;  3RSF A;  1LHP A;  4KAL A;  5TQI A;  5C40 A;  5CGA A;  3PL2 A;  3UBO A;  4E69 A;  2A9Z A;  1UA4 A;  1L2L A;  1BX4 A;  4B8S A;  4DU5 A;  4S1I B;  3HPD A;  2HQQ A;  4S1H A;  1RFT A;  2V78 A;  3RM5 A;  3K9E A;  3OTX A;  3RSQ A;  3IKH A;  4K8C A;  3QAI A;  2YXT A;  3RU2 A;  2QCV A;  4KAD A;  3RQX A;  3LKI A;  1RFV A;  1U2X A;  4JJP A;  3RTE A;  5C3Y A;  2Q5R A;  1DGM A;  3RT7 A;  3RTD A;  3B1N A;  1YHJ A;  3IQ0 A;  3B1Q A;  4XF6 A;  4XF7 A;  3RY7 A;  3FHX A;  4UBE A;  3HYO A;  3RTG A;  2C49 A;  4KBE A;  1RK2 A;  1VM7 A;  3RQH A;  4N08 A;  3RRF A;  4S1I A;  3B1R A;  3UQ6 A;  3NC9 A;  3NC2 A;  2AJR A;  2XTB A;  1GC5 A;  1LIO A;  3BF5 A;  1VI9 A;  1YGJ A;  3RSS A;  5F11 A;  3IE7 A;  3CQD A;  4GM6 A;  2F7K A;  2A9Y A;  1KYH A;  3NBV A;  4K9I A;  1RKD A;  3NL2 A;  4WJM A;  3UQ9 A;  2HW1 A;  3MBJ A;  1JXH A;  2PKM A;  3DZV A;  3RQ5 A;  3RS8 A;  4EOH A;  1TYY A;  1LIK A;  4C5L A;  2QHP A;  2RBC A;  4K8T A;  4PVV A;  1C3Q A;  2ABS A;  1TZ3 A;  1LII A;  2I6B A;  4K8P A;  5BYE A;  3Q1Y A;  3HIC A;  4E8W A;  2AJP A;  3QA2 A;  4O1L A;  4K9C A;  3IBQ A;  5BYD A;  1RFU A;  2C4E A;  5CGE A;  5C3Z A;  3FHY A;  4B8R A;  1V1S A;  4K93 A;  2DCN A;  3NM1 A;  3ZS7 A;  3RO4 A;  4DC3 A;  5C41 A;  5B6A A;  4C5N A;  4E8Y A;  2F02 A;  3B1O A;  2AB8 A;  3GO7 A;  3MBH A;  5CM5 A;  5TRW A;  3KEU A;  1UB0 A;  4E3A A;  5BYC A;  2DDW A;  1RKS A;  3GO6 A;  3RTC A;  2JGV A;  3B3L A;  3DRW A;  3RU3 A;  4EBU A;  3LOO A;  3Q92 A;  2AWD A;  1TZ6 A;  3RQ8 A;  3RRJ A;  1JXI A;  1V1B A;  3N1C A;  4U7X A;  3RQ2 A;  3RQ6 A;  3KD6 A;  1V19 A;  1YGK A;  3B1P A;  2PKK A;  3NL5 A;  4LCA A;  3RPZ A;  3UMP A;  4N09 A;  3NL6 A;  3VAQ A;  1WYE A;  5BYF A;  4EN4 A;  3RTA A;  4C5J A;  3IN1 A;  4JKS A;  4KAN A;  3NL3 A;  5F0Z A;  2ABQ A;  4XCK A;  3RSG A;  4LBG A;  3IH0 A;  3RQQ A;  2DDM A;  4O1G A;  2FV7 A;  4YL5 A;  3VAS A;  2PKF A;  3NM3 A;  1EKQ A;  4K8K A;  4LBX A;  4X8F A;  2R3E A;  1RKA A;  2I5B A;  2R3B A;  2PKN A;  3EWM A;  3H74 A;  3RS9 A;  4KAH A;  3I3Y A;  1LHR A;  4JKU A; 
#chains in the Genus database with same CATH topology
 4CVL A;  3UQE A;  3W4S A;  3NCA A;  3K5W A;  3ZM6 A;  4C5K A;  3GBU A;  3RPH A;  3H49 A;  3RTB A;  4LC4 A;  2JG5 A;  5A5F A;  3LHX A;  2DDO A;  2JG1 A;  3BGK A;  4S1M A;  2AX3 A;  4HV4 A;  3RSF A;  3QCZ A;  5CGA A;  3PL2 A;  1L2L A;  1BX4 A;  4B8S A;  3RM5 A;  3K9E A;  4K8C A;  3QAI A;  2YXT A;  2QCV A;  3RTE A;  2Y66 A;  1YHJ A;  3B1Q A;  4XF6 A;  4C12 A;  4KBE A;  3RRF A;  1GC5 A;  3RSS A;  1KYH A;  1P31 A;  3ZM5 A;  5A5E A;  2AM2 A;  2QHP A;  4K8T A;  3HJ6 A;  1C3Q A;  2ABS A;  3HIC A;  4O1L A;  4QF5 A;  2C4E A;  5CGE A;  5C3Z A;  1W7K A;  3ZS7 A;  4C5N A;  1JBV A;  1EEH A;  3HN7 A;  2AWD A;  2F00 A;  3RQ8 A;  1UAG A;  1JXI A;  3N1C A;  4U7X A;  3RQ2 A;  3RPZ A;  1WYE A;  4EN4 A;  3RTA A;  5F0Z A;  3RSG A;  4LBG A;  1W78 A;  3VAS A;  1EKQ A;  4CVM A;  2R3B A;  2PKN A;  3EWM A;  4EUM A;  3UQD A;  4E84 A;  1LIJ A;  4YWR A;  1ESJ A;  1TD2 A;  3RRB A;  2UUO A;  4E8Z A;  3RT9 A;  2NWH A;  3PZS A;  1E0D A;  2AFB A;  2YXU A;  3KTN A;  3NBW A;  5EY7 A;  1LHP A;  4KAL A;  4C13 A;  2A9Z A;  4DU5 A;  4CVK A;  3OTX A;  4KAD A;  1RFV A;  4JJP A;  1DGM A;  3RT7 A;  3B1N A;  4XF7 A;  1FGS A;  3RY7 A;  3FHX A;  2AM1 A;  1VM7 A;  3RQH A;  3B1R A;  3UQ6 A;  3NC9 A;  1VI9 A;  3IE7 A;  3CQD A;  2UAG A;  2F7K A;  4QDI A;  3UAG A;  4WJM A;  3UQ9 A;  2HW1 A;  3MBJ A;  2GCA A;  1TYY A;  1LIK A;  2RBC A;  1TZ3 A;  1LII A;  5BYE A;  2Y68 A;  3ZL8 A;  1RFU A;  2VOR A;  3FHY A;  1V1S A;  4K93 A;  3NM1 A;  2VTD A;  4E8Y A;  2F02 A;  3B1O A;  3GO7 A;  3NRS A;  5CM5 A;  3KEU A;  5BYC A;  2DDW A;  3GO6 A;  3DRW A;  3B3L A;  4EBU A;  1TZ6 A;  3RQ6 A;  1V19 A;  4LCA A;  4N09 A;  3VAQ A;  3IN1 A;  2JFF A;  3NL3 A;  1P3D A;  2DDM A;  4LBX A;  3H74 A;  3I3Y A;  2VAR A;  3UMO A;  5EYN A;  1ESQ A;  3JUL A;  2VTE A;  3KZH A;  4BUC A;  2AA0 A;  1EKK A;  1V1A A;  2HLZ A;  4C5M A;  1GQT A;  1JBW A;  5TQI A;  3UBO A;  4E69 A;  1UA4 A;  2X5O A;  4S1H A;  2HQQ A;  1RFT A;  2V78 A;  3RU2 A;  3RQX A;  3IQ0 A;  3HYO A;  3RTG A;  2C49 A;  3NC2 A;  2AJR A;  2XTB A;  1LIO A;  2GC6 A;  2Y1O A;  1YGJ A;  5F11 A;  2A9Y A;  3NBV A;  1RKD A;  3NL2 A;  3DZV A;  3EAG A;  4E8W A;  2AJP A;  4UAG A;  5BYD A;  4K9C A;  4B8R A;  3RO4 A;  5B6A A;  5TRW A;  3MBH A;  1UB0 A;  1RKS A;  2XJA A;  3RTC A;  2JGV A;  3RU3 A;  3N2A A;  3Q92 A;  3RRJ A;  3KD6 A;  1YGK A;  3B1P A;  2PKK A;  3UMP A;  3NL6 A;  2WTZ A;  4JKS A;  2ABQ A;  4XCK A;  2GCB A;  3RQQ A;  4O1G A;  2FV7 A;  2PKF A;  3NM3 A;  4K8K A;  4X8F A;  2I5B A;  1VK4 A;  2I6A A;  3LJS A;  4XDA A;  3RRE A;  2XPC A;  2Y67 A;  5COJ A;  5C40 A;  4S1I B;  3HPD A;  1GQY A;  3RSQ A;  3IKH A;  1J6U A;  5C3Y A;  3LKI A;  1U2X A;  2Q5R A;  2GC5 A;  3RTD A;  4UBE A;  1RK2 A;  4N08 A;  4S1I A;  3PYZ A;  3BF5 A;  2JFG A;  4GM6 A;  4K9I A;  1JXH A;  2PKM A;  3RQ5 A;  3RS8 A;  4EOH A;  4C5L A;  1GQQ A;  4PVV A;  4K8P A;  2I6B A;  3Q1Y A;  3QA2 A;  3IBQ A;  2WJP A;  3LK7 A;  5C41 A;  2DCN A;  4DC3 A;  1GG4 A;  2AB8 A;  4E3A A;  3LOO A;  2UUP A;  1E8C A;  2VOS A;  1V1B A;  4BUB A;  4ZIY A;  2JFH A;  1O5Z A;  3NL5 A;  5BYF A;  4C5J A;  4KAN A;  3IH0 A;  4YL5 A;  2R3E A;  1RKA A;  3RS9 A;  4KAH A;  1LHR A;  4JKU A; 
#chains in the Genus database with same CATH homology
 1VK4 A;  3UQE A;  4EUM A;  3UQD A;  2VAR A;  3UMO A;  2I6A A;  4E84 A;  3LJS A;  5EYN A;  3W4S A;  3NCA A;  3K5W A;  1LIJ A;  4YWR A;  4C5K A;  3GBU A;  1ESJ A;  3RPH A;  1ESQ A;  4XDA A;  1TD2 A;  3H49 A;  3JUL A;  3RRB A;  3RTB A;  4LC4 A;  2JG5 A;  3KZH A;  3LHX A;  2DDO A;  4E8Z A;  2AA0 A;  3RT9 A;  2NWH A;  2JG1 A;  3PZS A;  3RRE A;  1EKK A;  2AFB A;  2YXU A;  3BGK A;  3KTN A;  3NBW A;  4S1M A;  2AX3 A;  1V1A A;  5COJ A;  5EY7 A;  2HLZ A;  4C5M A;  1GQT A;  3RSF A;  1LHP A;  4KAL A;  5TQI A;  5C40 A;  5CGA A;  3PL2 A;  3UBO A;  4E69 A;  2A9Z A;  1UA4 A;  1L2L A;  1BX4 A;  4B8S A;  4DU5 A;  4S1I B;  3HPD A;  2HQQ A;  4S1H A;  1RFT A;  2V78 A;  3RM5 A;  3K9E A;  3OTX A;  3RSQ A;  3IKH A;  4K8C A;  3QAI A;  2YXT A;  3RU2 A;  2QCV A;  4KAD A;  3RQX A;  3LKI A;  1U2X A;  1RFV A;  4JJP A;  3RTE A;  5C3Y A;  2Q5R A;  1DGM A;  3RT7 A;  3RTD A;  3B1N A;  1YHJ A;  3IQ0 A;  3B1Q A;  4XF6 A;  4XF7 A;  3RY7 A;  3FHX A;  4UBE A;  3HYO A;  3RTG A;  2C49 A;  4KBE A;  1RK2 A;  1VM7 A;  3RQH A;  4N08 A;  3RRF A;  4S1I A;  3B1R A;  3UQ6 A;  3NC9 A;  3NC2 A;  2AJR A;  2XTB A;  1GC5 A;  1LIO A;  3BF5 A;  1VI9 A;  1YGJ A;  3RSS A;  5F11 A;  3IE7 A;  3CQD A;  4GM6 A;  2F7K A;  2A9Y A;  1KYH A;  3NBV A;  4K9I A;  1RKD A;  3NL2 A;  4WJM A;  3UQ9 A;  2HW1 A;  3MBJ A;  1JXH A;  2PKM A;  3DZV A;  3RQ5 A;  3RS8 A;  4EOH A;  1TYY A;  1LIK A;  4C5L A;  2QHP A;  2RBC A;  4K8T A;  4PVV A;  3HJ6 A;  1C3Q A;  2ABS A;  1TZ3 A;  1LII A;  2I6B A;  4K8P A;  5BYE A;  3Q1Y A;  3HIC A;  4E8W A;  2AJP A;  3QA2 A;  4O1L A;  4K9C A;  3IBQ A;  5BYD A;  1RFU A;  2C4E A;  5CGE A;  5C3Z A;  3FHY A;  4B8R A;  1V1S A;  4K93 A;  2DCN A;  3NM1 A;  3ZS7 A;  3RO4 A;  4DC3 A;  5C41 A;  5B6A A;  4C5N A;  4E8Y A;  2F02 A;  3B1O A;  2AB8 A;  3GO7 A;  3MBH A;  5CM5 A;  5TRW A;  3KEU A;  1UB0 A;  4E3A A;  5BYC A;  2DDW A;  1RKS A;  3GO6 A;  3RTC A;  3DRW A;  2JGV A;  3B3L A;  3RU3 A;  4EBU A;  3LOO A;  3Q92 A;  2AWD A;  1TZ6 A;  3RQ8 A;  3RRJ A;  1JXI A;  1V1B A;  3N1C A;  4U7X A;  3RQ2 A;  3RQ6 A;  3KD6 A;  1V19 A;  1YGK A;  3B1P A;  2PKK A;  3NL5 A;  4LCA A;  3RPZ A;  3UMP A;  4N09 A;  3NL6 A;  3VAQ A;  1WYE A;  5BYF A;  4EN4 A;  3RTA A;  4C5J A;  3IN1 A;  4JKS A;  4KAN A;  3NL3 A;  5F0Z A;  2ABQ A;  4XCK A;  3RSG A;  4LBG A;  3IH0 A;  3RQQ A;  2DDM A;  4O1G A;  2FV7 A;  4YL5 A;  3VAS A;  2PKF A;  3NM3 A;  1EKQ A;  4K8K A;  4LBX A;  4X8F A;  2R3E A;  1RKA A;  2I5B A;  2R3B A;  2PKN A;  3EWM A;  3H74 A;  3RS9 A;  4KAH A;  3I3Y A;  1LHR A;  4JKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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