5HL7J

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with lefamulin
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
138
structure length
138
Chain Sequence
MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREELG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 18
structure length 138
sequence length 138
ec nomenclature
pdb deposition date 2016-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
J PF00252 Ribosomal_L16 Ribosomal protein L16p/L10e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1170.10 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Ribosomal protein L10e/L16 5hl7J01
1M90J 2OTLH 3CMEH 4IOCJ 2OTJH 3PIPJ 1KC8J 5GAHN 1K9MJ 1YJWH 2ZJQJ 1YI2H 3I56H 1VQ8H 4UY8M 1VQ7H 2QEXH 1VQ9H 1M1KJ 3PIOJ 3CMAH 3CCSH 1YJNH 1VQMH 4IO9J 5GAGN 1YIJH 1YHQH 5DM7J 3I55H 1K73J 1KQSH 1VQ4H 5AN9F 1VQNH 1WKIA 3CXCH 3CCQH 1VQ6H 1VQ5H 1Q81J 1S72H 4WCEJ 3CCVH 1VQOH 1W2BH 1QVFH 5MLCO 5GAEN 1Y69K 1K8AJ 1JJ2H 3OW2H 1Q7YJ 2PA2A 2ZJRJ 1YITH 1KD1J 5GADN 3J7ZM 1Q86J 1N8RJ 3CCRH 3DLLJ 3G71H 1QVGH 1NJIJ 5DM6J 3G6EH 3CCMH 2QA4H 3CC4H 5JVHJ 1Q82J 3CCLH 1YJ9H 3CF5J 2ZJPJ 1VQPH 3CC7H 3CCUH 5HL7J 4WFBJ 5JVGJ 1VQKH 3CCEH 5H1SO 4WFNJ 3CD6H 4WF9J 1VQLH 3CC2H 4WFAJ 4U67J 4IOAJ 3G4SH 3CCJH 3CPWH
chains in the Genus database with same CATH superfamily
2I14A 3NRZC 1N5WB 1M90J 2OTLH 2QIEA 5HUPA 3CMEH 4IOCJ 1AZYA 2OTJH 3PIPJ 5HUOA 3NVWC 1KC8J 3L0GA 5GAHN 1K9MJ 2B7QA 4USAA 1JRPB 2OMDA 3C2RA 1N60B 3C2VA 4AP8A 2ZJQJ 1YI2H 1YJWH 3I56H 1VQ8H 2DSJA 4UY8M 1VQ7H 1YTKA 2QEXH 1VQ9H 1M1KJ 3PIOJ 4X46A 4XR5A 3CMAH 3CCSH 3CPWH 3C2OA 5EY3A 1YJNH 3GNNA 4US8A 1VDVA 2W55B 1VQMH 1V97A 5GAGN 4IO9J 1YIJH 2J0FA 1YHQH 2E3TA 5DM7J 3I55H 2B7NA 3C2EA 3ETRC 1K73J 2I1OA 1KQSH 1FO4A 1VQ4H 5AN9F 4KWWA 1N62B 5EP8A 1VQNH 1RM6A 3H5QA 4C7YA 2JBMA 4C7ZA 1QPRA 4KWVA 1WKIA 3CXCH 1X1OA 3CCQH 1N5XA 1VQ6H 2W3SB 3AMZA 1VQ5H 1Q81J 1FIQC 3WO0A 3NVZC 1BRWA 1S72H 3PAJA 4WCEJ 3CCVH 1VQOH 1W2BH 2WK5A 3L4PA 1QVFH 2TPTA 2W54B 5MLCO 3NVYC 1WYGA 1VLBA 2W3RB 5GAEN 1Y69K 1QPQA 1YTEA 3NS1C 3BIIE 1K8AJ 1FMAE 4ZOHA 1NVJA 1JJ2H 3SR6C 3OW2H 1Q7YJ 2PA2A 2WP4A 1O4UA 1FM0E 2ZJRJ 1NVIE 1OTPA 3AM9A 3VMMA 1QAPA 1YITH 1KD1J 5GADN 1N61B 3J7ZM 1Q86J 1N8RJ 3CCRH 1QPOA 4GA5A 4YEKA 4EADA 3EUB4 4GA4A 3DLLJ 3G71H 1QVGH 3AN1A 5AYYA 1NJIJ 5DM6J 3G6EH 2WK6A 3CCMH 2QA4H 1N63B 3CC4H 4GA6A 3RPFA 5JVHJ 5AYZA 3FC4A 5MPOC 1Q82J 5AYXA 3CCLH 1YJ9H 3B9JC 3CF5J 1SIJA 2ZJPJ 2B7PA 4LHMA 1FFUB 1VQPH 3CC7H 3WO1A 3TQVA 5HL7J 3CCUH 4US9A 4WFBJ 5JVGJ 1VQKH 3CCEH 4EAFA 1FFVB 5H1SO 1UOUA 3FAHA 5HULA 1YTDA 4WFNJ 1QPNA 3CD6H 4I9AA 4WF9J 1VQLH 3C2FA 3CC2H 1DGJA 4WFAJ 1ZXIB 1JROB 3WNZA 4U67J 4IOAJ 4YYYA 1SB3A 3G4SH 4C80A 2Q5WE 3CCJH 3NVVC
chains in the Genus database with same CATH topology
1M90J 2OTLH 3CMEH 4IOCJ 2OTJH 3PIPJ 1KC8J 5GAHN 1K9MJ 1YJWH 2ZJQJ 1YI2H 3I56H 1VQ8H 4UY8M 1VQ7H 2QEXH 1VQ9H 1M1KJ 3PIOJ 3CMAH 3CCSH 1YJNH 1VQMH 4IO9J 5GAGN 1YIJH 1YHQH 5DM7J 3I55H 1K73J 1KQSH 1VQ4H 5AN9F 1VQNH 1WKIA 3CXCH 3CCQH 1VQ6H 1VQ5H 1Q81J 1S72H 4WCEJ 3CCVH 1VQOH 1W2BH 1QVFH 5MLCO 5GAEN 1Y69K 1K8AJ 1JJ2H 3OW2H 1Q7YJ 2PA2A 2ZJRJ 1YITH 1KD1J 5GADN 3J7ZM 1Q86J 1N8RJ 3CCRH 3DLLJ 3G71H 1QVGH 1NJIJ 5DM6J 3G6EH 3CCMH 2QA4H 3CC4H 5JVHJ 1Q82J 3CCLH 1YJ9H 3CF5J 2ZJPJ 1VQPH 3CC7H 3CCUH 5HL7J 4WFBJ 5JVGJ 1VQKH 3CCEH 5H1SO 4WFNJ 3CD6H 4WF9J 1VQLH 3CC2H 4WFAJ 4U67J 4IOAJ 3G4SH 3CCJH 3CPWH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M90 J;  2OTL H;  3CME H;  4IOC J;  2OTJ H;  3PIP J;  1KC8 J;  5GAH N;  1K9M J;  1YJW H;  2ZJQ J;  1YI2 H;  3I56 H;  1VQ8 H;  4UY8 M;  1VQ7 H;  2QEX H;  1VQ9 H;  1M1K J;  3PIO J;  3CMA H;  3CCS H;  1YJN H;  1VQM H;  4IO9 J;  5GAG N;  1YIJ H;  1YHQ H;  5DM7 J;  3I55 H;  1K73 J;  1KQS H;  1VQ4 H;  5AN9 F;  1VQN H;  1WKI A;  3CXC H;  3CCQ H;  1VQ6 H;  1VQ5 H;  1Q81 J;  1S72 H;  4WCE J;  3CCV H;  1VQO H;  1W2B H;  1QVF H;  5MLC O;  5GAE N;  1Y69 K;  1K8A J;  1JJ2 H;  3OW2 H;  1Q7Y J;  2PA2 A;  2ZJR J;  1YIT H;  1KD1 J;  5GAD N;  3J7Z M;  1Q86 J;  1N8R J;  3CCR H;  3DLL J;  3G71 H;  1QVG H;  1NJI J;  5DM6 J;  3G6E H;  3CCM H;  2QA4 H;  3CC4 H;  5JVH J;  1Q82 J;  3CCL H;  1YJ9 H;  3CF5 J;  2ZJP J;  1VQP H;  3CC7 H;  3CCU H;  5HL7 J;  4WFB J;  5JVG J;  1VQK H;  3CCE H;  5H1S O;  4WFN J;  3CD6 H;  4WF9 J;  1VQL H;  3CC2 H;  4WFA J;  4U67 J;  4IOA J;  3G4S H;  3CCJ H;  3CPW H; 
#chains in the Genus database with same CATH topology
 2I14 A;  3NRZ C;  1N5W B;  1M90 J;  2OTL H;  2QIE A;  5HUP A;  3CME H;  4IOC J;  1AZY A;  2OTJ H;  3PIP J;  5HUO A;  3NVW C;  1KC8 J;  3L0G A;  5GAH N;  1K9M J;  2B7Q A;  4USA A;  1JRP B;  2OMD A;  3C2R A;  1N60 B;  3C2V A;  4AP8 A;  2ZJQ J;  1YI2 H;  1YJW H;  3I56 H;  1VQ8 H;  2DSJ A;  4UY8 M;  1VQ7 H;  1YTK A;  2QEX H;  1VQ9 H;  1M1K J;  3PIO J;  4X46 A;  4XR5 A;  3CMA H;  3CCS H;  3CPW H;  3C2O A;  5EY3 A;  1YJN H;  3GNN A;  4US8 A;  1VDV A;  2W55 B;  1VQM H;  1V97 A;  5GAG N;  4IO9 J;  1YIJ H;  2J0F A;  1YHQ H;  2E3T A;  5DM7 J;  3I55 H;  2B7N A;  3C2E A;  3ETR C;  1K73 J;  2I1O A;  1KQS H;  1FO4 A;  1VQ4 H;  5AN9 F;  4KWW A;  1N62 B;  5EP8 A;  1VQN H;  1RM6 A;  3H5Q A;  4C7Y A;  2JBM A;  4C7Z A;  1QPR A;  4KWV A;  1WKI A;  3CXC H;  1X1O A;  3CCQ H;  1N5X A;  1VQ6 H;  2W3S B;  3AMZ A;  1VQ5 H;  1Q81 J;  1FIQ C;  3WO0 A;  3NVZ C;  1BRW A;  1S72 H;  3PAJ A;  4WCE J;  3CCV H;  1VQO H;  1W2B H;  2WK5 A;  3L4P A;  1QVF H;  2TPT A;  2W54 B;  5MLC O;  3NVY C;  1WYG A;  1VLB A;  2W3R B;  5GAE N;  1Y69 K;  1QPQ A;  1YTE A;  3NS1 C;  3BII E;  1K8A J;  1FMA E;  4ZOH A;  1NVJ A;  1JJ2 H;  3SR6 C;  3OW2 H;  1Q7Y J;  2PA2 A;  2WP4 A;  1O4U A;  1FM0 E;  2ZJR J;  1NVI E;  1OTP A;  3AM9 A;  3VMM A;  1QAP A;  1YIT H;  1KD1 J;  5GAD N;  1N61 B;  3J7Z M;  1Q86 J;  1N8R J;  3CCR H;  1QPO A;  4GA5 A;  4YEK A;  4EAD A;  3EUB 4;  4GA4 A;  3DLL J;  3G71 H;  1QVG H;  3AN1 A;  5AYY A;  1NJI J;  5DM6 J;  3G6E H;  2WK6 A;  3CCM H;  2QA4 H;  1N63 B;  3CC4 H;  4GA6 A;  3RPF A;  5JVH J;  5AYZ A;  3FC4 A;  5MPO C;  1Q82 J;  5AYX A;  3CCL H;  1YJ9 H;  3B9J C;  3CF5 J;  1SIJ A;  2ZJP J;  2B7P A;  4LHM A;  1FFU B;  1VQP H;  3CC7 H;  3WO1 A;  3TQV A;  5HL7 J;  3CCU H;  4US9 A;  4WFB J;  5JVG J;  1VQK H;  3CCE H;  4EAF A;  1FFV B;  5H1S O;  1UOU A;  3FAH A;  5HUL A;  1YTD A;  4WFN J;  1QPN A;  3CD6 H;  4I9A A;  4WF9 J;  1VQL H;  3C2F A;  3CC2 H;  1DGJ A;  4WFA J;  1ZXI B;  1JRO B;  3WNZ A;  4U67 J;  4IOA J;  4YYY A;  1SB3 A;  3G4S H;  4C80 A;  2Q5W E;  3CCJ H;  3NVV C; 
#chains in the Genus database with same CATH homology
 1M90 J;  2OTL H;  3CME H;  4IOC J;  2OTJ H;  3PIP J;  1KC8 J;  5GAH N;  1K9M J;  1YJW H;  2ZJQ J;  1YI2 H;  3I56 H;  1VQ8 H;  4UY8 M;  1VQ7 H;  2QEX H;  1VQ9 H;  1M1K J;  3PIO J;  3CMA H;  3CCS H;  1YJN H;  1VQM H;  4IO9 J;  5GAG N;  1YIJ H;  1YHQ H;  5DM7 J;  3I55 H;  1K73 J;  1KQS H;  1VQ4 H;  5AN9 F;  1VQN H;  1WKI A;  3CXC H;  3CCQ H;  1VQ6 H;  1VQ5 H;  1Q81 J;  1S72 H;  4WCE J;  3CCV H;  1VQO H;  1W2B H;  1QVF H;  5MLC O;  5GAE N;  1Y69 K;  1K8A J;  1JJ2 H;  3OW2 H;  1Q7Y J;  2PA2 A;  2ZJR J;  1YIT H;  1KD1 J;  5GAD N;  3J7Z M;  1Q86 J;  1N8R J;  3CCR H;  3DLL J;  3G71 H;  1QVG H;  1NJI J;  5DM6 J;  3G6E H;  3CCM H;  2QA4 H;  3CC4 H;  5JVH J;  1Q82 J;  3CCL H;  1YJ9 H;  3CF5 J;  2ZJP J;  1VQP H;  3CC7 H;  3CCU H;  5HL7 J;  4WFB J;  5JVG J;  1VQK H;  3CCE H;  5H1S O;  4WFN J;  3CD6 H;  4WF9 J;  1VQL H;  3CC2 H;  4WFA J;  4U67 J;  4IOA J;  3G4S H;  3CCJ H;  3CPW H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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