1EAAA

Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
243
structure length
243
Chain Sequence
IPPIPPVDFAKYGEIEEVPMTRLMQIGATNLHRSWLNVPHVTQFESADITELEAFRVAQKAVAKKAGVKLTVLPLLLKACAYLLKELPDFNSSLAPSGQALIRKKYVHIGFAVDTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGACFTISSLGHIGGTAFTPIVNAPEVAILGVSKASMQPVWDGKAFQPRLMLPLSLSYDHRVINGAAAARFTKRLGDLLADIRAILL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
pubmed doi rcsb
molecule tags Dihydrolipoamide acetyltransferase
source organism Azotobacter vinelandii
molecule keywords DIHYDROLIPOYL-TRANSACETYLASE
total genus 67
structure length 243
sequence length 243
ec nomenclature ec 2.3.1.12: Dihydrolipoyllysine-residue acetyltransferase.
pdb deposition date 1992-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 1eaaA00
5KJWA 1EAAA 3FP0A 2JGPA 2XR7A 1XMDA 2CLAA 5DU9A 1XL8A 1NOCB 2RKTA 1EACA 2E1VA 2E1TA 1CLAA 1SCZA 3U9BA 1E2OA 5KJSA 3B30A 5KJVA 3FOTA 1DPDA 2XHGA 1Q9JA 5KJTA 1DPBA 3MAEA 1L5AA 2VSQA 4G22A 2IHWA 2II3A 2E1UA 1CIAA 4G0BA 5FALA 1Q23A 2II5A 2ZBAA 1QCAA 1DPCA 1XL7A 3L60A 3U9FA 4HVMA 1EADA 1XMCA 2BGHA 4JN5A 5DUAA 4CLAA 3CLAA 4KE4A 4N72A 5T3EA 1EAEA 2II4A 4G2MA 4KECA 4JN3A 5KJUA 1EABA 2RKVA 1C4TA 1EAFA 2I9DA 5FANA 1PD5A 3B2SA
chains in the Genus database with same CATH superfamily
5DU9A 5KJSA 2XHGA 2E1UA 4EP9A 3L60A 1NDFA 2H3WA 4N72A 2II4A 4JN3A 1EABA 1EAFA 3B2SA 2DEBA 2JGPA 2XR7A 1XMDA 1NM8A 2RKTA 2E1TA 3U9BA 1NDIA 1T7OA 5KJVA 1T1UA 1L5AA 2IHWA 1CIAA 5FALA 1Q23A 2ZBAA 1DPCA 4HVMA 1EADA 4JN5A 5DUAA 4KE4A 1EAEA 4KECA 2FY4A 5KJUA 1C4TA 2E1VA 5KJWA 1EAAA 2FYOA 1NOCB 2FY2A 2H3UA 1E2OA 2H3PA 1DPDA 1Q9JA 1DPBA 2VSQA 1T7NA 4G22A 1QCAA 1XMCA 2BGHA 1S5OA 4CLAA 5T3EA 2FY5A 2RKVA 2I9DA 1PD5A 4EYWA 1T7QA 2H4TA 1NDBA 3FP0A 2RCUA 2CLAA 1XL8A 1EACA 1CLAA 1SCZA 3B30A 3FOTA 5KJTA 3MAEA 2II3A 4G0BA 2II5A 1XL7A 3U9FA 3CLAA 4G2MA 2FW3A 4EPHA 2FY3A 5FANA 1Q6XA
chains in the Genus database with same CATH topology
5KJWA 1EAAA 3FP0A 2JGPA 2XR7A 1XMDA 2CLAA 5DU9A 1XL8A 1NOCB 2RKTA 1EACA 2E1VA 2E1TA 1CLAA 1SCZA 3U9BA 1E2OA 5KJSA 3B30A 5KJVA 3FOTA 1DPDA 2XHGA 1Q9JA 5KJTA 1DPBA 3MAEA 1L5AA 2VSQA 4G22A 2IHWA 2II3A 2E1UA 1CIAA 4G0BA 5FALA 1Q23A 2II5A 2ZBAA 1QCAA 1DPCA 1XL7A 3L60A 3U9FA 4HVMA 1EADA 1XMCA 2BGHA 4JN5A 5DUAA 4CLAA 3CLAA 4KE4A 4N72A 5T3EA 1EAEA 2II4A 4G2MA 4KECA 4JN3A 5KJUA 1EABA 2RKVA 1C4TA 1EAFA 2I9DA 5FANA 1PD5A 3B2SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KJW A;  1EAA A;  3FP0 A;  2JGP A;  2XR7 A;  1XMD A;  2CLA A;  5DU9 A;  1XL8 A;  1NOC B;  2RKT A;  1EAC A;  2E1V A;  2E1T A;  1CLA A;  1SCZ A;  3U9B A;  1E2O A;  5KJS A;  3B30 A;  5KJV A;  3FOT A;  1DPD A;  2XHG A;  1Q9J A;  5KJT A;  1DPB A;  3MAE A;  1L5A A;  2VSQ A;  4G22 A;  2IHW A;  2II3 A;  2E1U A;  1CIA A;  4G0B A;  5FAL A;  1Q23 A;  2II5 A;  2ZBA A;  1QCA A;  1DPC A;  1XL7 A;  3L60 A;  3U9F A;  4HVM A;  1EAD A;  1XMC A;  2BGH A;  4JN5 A;  5DUA A;  4CLA A;  3CLA A;  4KE4 A;  4N72 A;  5T3E A;  1EAE A;  2II4 A;  4G2M A;  4KEC A;  4JN3 A;  5KJU A;  1EAB A;  2RKV A;  1C4T A;  1EAF A;  2I9D A;  5FAN A;  1PD5 A;  3B2S A; 
#chains in the Genus database with same CATH topology
 5DU9 A;  5KJS A;  2XHG A;  2E1U A;  4EP9 A;  3L60 A;  1NDF A;  2H3W A;  4N72 A;  2II4 A;  4JN3 A;  1EAB A;  1EAF A;  3B2S A;  2DEB A;  2JGP A;  2XR7 A;  1XMD A;  1NM8 A;  2RKT A;  2E1T A;  3U9B A;  1NDI A;  1T7O A;  5KJV A;  1T1U A;  1L5A A;  2IHW A;  1CIA A;  5FAL A;  1Q23 A;  2ZBA A;  1DPC A;  4HVM A;  1EAD A;  4JN5 A;  5DUA A;  4KE4 A;  1EAE A;  4KEC A;  2FY4 A;  5KJU A;  1C4T A;  2E1V A;  5KJW A;  1EAA A;  2FYO A;  1NOC B;  2FY2 A;  2H3U A;  1E2O A;  2H3P A;  1DPD A;  1Q9J A;  1DPB A;  2VSQ A;  1T7N A;  4G22 A;  1QCA A;  1XMC A;  2BGH A;  1S5O A;  4CLA A;  5T3E A;  2FY5 A;  2RKV A;  2I9D A;  1PD5 A;  4EYW A;  1T7Q A;  2H4T A;  1NDB A;  3FP0 A;  2RCU A;  2CLA A;  1XL8 A;  1EAC A;  1CLA A;  1SCZ A;  3B30 A;  3FOT A;  5KJT A;  3MAE A;  2II3 A;  4G0B A;  2II5 A;  1XL7 A;  3U9F A;  3CLA A;  4G2M A;  2FW3 A;  4EPH A;  2FY3 A;  5FAN A;  1Q6X A; 
#chains in the Genus database with same CATH homology
 5KJW A;  1EAA A;  3FP0 A;  2JGP A;  2XR7 A;  1XMD A;  2CLA A;  5DU9 A;  1XL8 A;  1NOC B;  2RKT A;  1EAC A;  2E1V A;  2E1T A;  1CLA A;  1SCZ A;  3U9B A;  1E2O A;  5KJS A;  3B30 A;  5KJV A;  3FOT A;  1DPD A;  2XHG A;  1Q9J A;  5KJT A;  1DPB A;  3MAE A;  1L5A A;  2VSQ A;  4G22 A;  2IHW A;  2II3 A;  2E1U A;  1CIA A;  4G0B A;  5FAL A;  1Q23 A;  2II5 A;  2ZBA A;  1QCA A;  1DPC A;  1XL7 A;  3L60 A;  3U9F A;  4HVM A;  1EAD A;  1XMC A;  2BGH A;  4JN5 A;  5DUA A;  4CLA A;  3CLA A;  4KE4 A;  4N72 A;  5T3E A;  1EAE A;  2II4 A;  4G2M A;  4KEC A;  4JN3 A;  5KJU A;  1EAB A;  2RKV A;  1C4T A;  1EAF A;  2I9D A;  5FAN A;  1PD5 A;  3B2S A; 
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similar chains in the pdb database (?% sequence similarity)

 
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