5DU9A

First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 2a
Total Genus 142
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
142
sequence length
444
structure length
427
Chain Sequence
SVRHGLTSAQHCVWLAQQLDPRGAHYRTGSCLEIDGPLDHAVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPVPYTPVLLRHIDLSGHEDPEGEAQRWMDRDRATPLPLDRPGLSSHALFTLGGGRHLYYLGVHHIVIDGTSMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRAYWTGLFTDRPEPVSLRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIAGVAAFLHRTTGARDVVVSVPVTGRYGANARITPGMVSNRLPLRLAVRPGESFARVVETVSEAMSGLLAHSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLMRSISSGPTTDLNIVLTGTPESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAATVDEVALLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CDA peptide synthetase I
publication title Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases.
pubmed doi rcsb
source organism Streptomyces coelicolor (strain atcc baa-471 / a3(2) / m145)
molecule tags Phosphopantetheine binding protein
total genus 142
structure length 427
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-09-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 5du9A01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 5du9A02
3U9FA 4JN3A 2BGHA 2XR7A 3MAEA 4HVMA 2ZBAA 3U9BA 1XL7A 2II5A 5KJVA 5KJUA 2E1VA 1CLAA 3FOTA 1XMDA 2VSQA 1QCAA 1XL8A 4G2MA 1EABA 2I9DA 3B30A 4JN5A 1E2OA 5KJSA 1EACA 2RKTA 1PD5A 1EAEA 4G22A 4KECA 5KJTA 3FP0A 1Q23A 1XMCA 2CLAA 4KE4A 1DPBA 2RKVA 5FANA 1L5AA 5DUAA 2II4A 1DPCA 1NOCB 1C4TA 1EAFA 2E1UA 2IHWA 3L60A 4G0BA 4N72A 5DU9A 4CLAA 2II3A 1CIAA 1DPDA 1SCZA 2JGPA 3B2SA 5T3EA 5FALA 5KJWA 2E1TA 1Q9JA 3CLAA 1EADA 2XHGA 1EAAA
chains in the Genus database with same CATH superfamily
3U9FA 2BGHA 5KJVA 1XMDA 3B30A 1E2OA 2RKTA 1NDIA 2RCUA 4KE4A 1DPBA 2RKVA 1L5AA 1NOCB 1EAFA 4G0BA 3L60A 3B2SA 5FALA 5KJWA 5DUAA 2H3WA 2XHGA 4EPHA 3MAEA 2FY4A 2E1VA 3FOTA 1QCAA 2FY3A 4G2MA 1EACA 1PD5A 2FY2A 1XMCA 2H3PA 1NDBA 1T7OA 2H4TA 2IHWA 4CLAA 2II3A 2JGPA 5T3EA 2E1TA 4G22A 2FY5A 1EAAA 1T7QA 4JN3A 3U9BA 1XL7A 1NM8A 1S5OA 2VSQA 1XL8A 1EABA 2I9DA 4JN5A 5KJSA 1Q6XA 2H3UA 3FP0A 1Q23A 2FYOA 1T1UA 2E1UA 4N72A 5DU9A 3CLAA 4EP9A 4HVMA 2XR7A 2ZBAA 2II5A 5KJUA 4EYWA 1CLAA 2FW3A 1EAEA 4KECA 5KJTA 2CLAA 5FANA 1NDFA 2II4A 1DPCA 1C4TA 1CIAA 1DPDA 1SCZA 1Q9JA 1T7NA 2DEBA 1EADA
chains in the Genus database with same CATH topology
3U9FA 2BGHA 5KJVA 1XMDA 3B30A 1E2OA 2RKTA 1NDIA 2RCUA 4KE4A 1DPBA 2RKVA 1L5AA 1NOCB 1EAFA 4G0BA 3L60A 3B2SA 5FALA 5KJWA 5DUAA 2H3WA 2XHGA 4EPHA 3MAEA 2FY4A 2E1VA 3FOTA 1QCAA 2FY3A 4G2MA 1EACA 1PD5A 2FY2A 1XMCA 2H3PA 1NDBA 1T7OA 2IHWA 2H4TA 4CLAA 2II3A 2JGPA 5T3EA 2E1TA 4G22A 2FY5A 1EAAA 4JN3A 1T7QA 3U9BA 1XL7A 1NM8A 1S5OA 2VSQA 1XL8A 1EABA 2I9DA 4JN5A 5KJSA 1Q6XA 2H3UA 3FP0A 1Q23A 2FYOA 1T1UA 2E1UA 4N72A 5DU9A 3CLAA 4EP9A 4HVMA 2XR7A 2ZBAA 2II5A 5KJUA 4EYWA 1CLAA 2FW3A 1EAEA 4KECA 5KJTA 2CLAA 5FANA 1NDFA 2II4A 1DPCA 1C4TA 1CIAA 1DPDA 1SCZA 1Q9JA 1T7NA 2DEBA 1EADA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U9F A;  4JN3 A;  2BGH A;  2XR7 A;  3MAE A;  4HVM A;  2ZBA A;  3U9B A;  1XL7 A;  2II5 A;  5KJV A;  5KJU A;  2E1V A;  1CLA A;  3FOT A;  1XMD A;  2VSQ A;  1QCA A;  1XL8 A;  4G2M A;  1EAB A;  2I9D A;  3B30 A;  4JN5 A;  1E2O A;  5KJS A;  1EAC A;  2RKT A;  1PD5 A;  1EAE A;  4G22 A;  4KEC A;  5KJT A;  3FP0 A;  1Q23 A;  1XMC A;  2CLA A;  4KE4 A;  1DPB A;  2RKV A;  5FAN A;  1L5A A;  5DUA A;  2II4 A;  1DPC A;  1NOC B;  1C4T A;  1EAF A;  2E1U A;  2IHW A;  3L60 A;  4G0B A;  4N72 A;  5DU9 A;  4CLA A;  2II3 A;  1CIA A;  1DPD A;  1SCZ A;  2JGP A;  3B2S A;  5T3E A;  5FAL A;  5KJW A;  2E1T A;  1Q9J A;  3CLA A;  1EAD A;  2XHG A;  1EAA A; 
#chains in the Genus database with same CATH topology
 3U9F A;  2BGH A;  5KJV A;  1XMD A;  3B30 A;  1E2O A;  2RKT A;  1NDI A;  2RCU A;  4KE4 A;  1DPB A;  2RKV A;  1L5A A;  1NOC B;  1EAF A;  4G0B A;  3L60 A;  3B2S A;  5FAL A;  5KJW A;  5DUA A;  2H3W A;  2XHG A;  4EPH A;  3MAE A;  2FY4 A;  2E1V A;  3FOT A;  1QCA A;  2FY3 A;  4G2M A;  1EAC A;  1PD5 A;  2FY2 A;  1XMC A;  2H3P A;  1NDB A;  1T7O A;  2H4T A;  2IHW A;  4CLA A;  2II3 A;  2JGP A;  5T3E A;  2E1T A;  4G22 A;  2FY5 A;  1EAA A;  1T7Q A;  4JN3 A;  3U9B A;  1XL7 A;  1NM8 A;  1S5O A;  2VSQ A;  1XL8 A;  1EAB A;  2I9D A;  4JN5 A;  5KJS A;  1Q6X A;  2H3U A;  3FP0 A;  1Q23 A;  2FYO A;  1T1U A;  2E1U A;  4N72 A;  5DU9 A;  3CLA A;  4EP9 A;  4HVM A;  2XR7 A;  2ZBA A;  2II5 A;  5KJU A;  4EYW A;  1CLA A;  2FW3 A;  1EAE A;  4KEC A;  5KJT A;  2CLA A;  5FAN A;  1NDF A;  2II4 A;  1DPC A;  1C4T A;  1CIA A;  1DPD A;  1SCZ A;  1Q9J A;  1T7N A;  2DEB A;  1EAD A; 
#chains in the Genus database with same CATH homology
 3U9F A;  2BGH A;  5KJV A;  1XMD A;  3B30 A;  1E2O A;  2RKT A;  1NDI A;  2RCU A;  4KE4 A;  1DPB A;  2RKV A;  1L5A A;  1NOC B;  1EAF A;  4G0B A;  3L60 A;  3B2S A;  5FAL A;  5KJW A;  5DUA A;  2H3W A;  2XHG A;  4EPH A;  3MAE A;  2FY4 A;  2E1V A;  3FOT A;  1QCA A;  2FY3 A;  4G2M A;  1EAC A;  1PD5 A;  2FY2 A;  1XMC A;  2H3P A;  1NDB A;  1T7O A;  2IHW A;  2H4T A;  4CLA A;  2II3 A;  2JGP A;  5T3E A;  2E1T A;  4G22 A;  2FY5 A;  1EAA A;  4JN3 A;  1T7Q A;  3U9B A;  1XL7 A;  1NM8 A;  1S5O A;  2VSQ A;  1XL8 A;  1EAB A;  2I9D A;  4JN5 A;  5KJS A;  1Q6X A;  2H3U A;  3FP0 A;  1Q23 A;  2FYO A;  1T1U A;  2E1U A;  4N72 A;  5DU9 A;  3CLA A;  4EP9 A;  4HVM A;  2XR7 A;  2ZBA A;  2II5 A;  5KJU A;  4EYW A;  1CLA A;  2FW3 A;  1EAE A;  4KEC A;  5KJT A;  2CLA A;  5FAN A;  1NDF A;  2II4 A;  1DPC A;  1C4T A;  1CIA A;  1DPD A;  1SCZ A;  1Q9J A;  1T7N A;  2DEB A;  1EAD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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