4JN3A

Crystal structures of the first condensation domain of the cda synthetase
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
446
structure length
446
Chain Sequence
NSSVRHGLTSAQHEVWLAQQLDPRGAHYRTGSCLEIDGPLDHAVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPEGSAAVEDPDGVPYTPVLLRHIDLSGHEDPEGEAQRWMDRDRATPLPLDRPGLSSHALFTLGGGRHLYYLGVHHIVIDGTSMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRAYWTGLFTDRPEPVSLTGRGGGRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIAGVAAFLHRTTGARDVVVSVPVTGRYGANARITPGMVSNRLPLRLAVRPGESFARVVETVSEAMSGLLAHSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLMRSISSGPTTDLNIVLTGTPESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAATVDEVALLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CDA peptide synthetase I
publication title Crystal Structures of the First Condensation Domain of CDA Synthetase Suggest Conformational Changes during the Synthetic Cycle of Nonribosomal Peptide Synthetases.
pubmed doi rcsb
source organism Streptomyces coelicolor
molecule tags Biosynthetic protein
total genus 141
structure length 446
sequence length 446
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-03-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 4jn3A01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 4jn3A02
1DPBA 2IHWA 1DPDA 3B2SA 1XL8A 5KJSA 1XL7A 2II4A 1DPCA 1E2OA 5DUAA 1Q23A 1EAAA 2E1VA 5FANA 2RKTA 1EAEA 1XMCA 1CIAA 1EABA 1EACA 5KJTA 4G2MA 2JGPA 1C4TA 5KJUA 2E1UA 2VSQA 1L5AA 4JN3A 2II3A 2I9DA 2II5A 3L60A 2E1TA 1PD5A 1NOCB 3MAEA 3U9BA 4CLAA 2BGHA 1XMDA 1EAFA 2ZBAA 4G22A 3FOTA 1CLAA 3FP0A 4JN5A 5DU9A 5T3EA 2XR7A 1EADA 3U9FA 3CLAA 4KECA 2XHGA 4HVMA 3B30A 5KJWA 2RKVA 5FALA 2CLAA 1QCAA 4KE4A 5KJVA 4N72A 1SCZA 1Q9JA 4G0BA
chains in the Genus database with same CATH superfamily
1DPDA 3B2SA 2II4A 1CIAA 5KJTA 1C4TA 2E1UA 1L5AA 3L60A 2FW3A 1NOCB 1NM8A 1S5OA 3CLAA 1NDIA 2H3PA 2H4TA 4KE4A 5KJVA 4N72A 1NDBA 1XL8A 1XL7A 2DEBA 2E1VA 1EAAA 5FANA 1EAEA 1XMCA 1EACA 4G2MA 2II5A 4CLAA 2BGHA 3FOTA 4EYWA 2XHGA 5KJWA 1Q23A 4EPHA 4EP9A 1DPCA 1Q9JA 1T7OA 2RCUA 5KJUA 2VSQA 4JN3A 1T7QA 1PD5A 1T1UA 3MAEA 2ZBAA 2FY2A 4G22A 3FP0A 5T3EA 2XR7A 1EADA 3B30A 1QCAA 1SCZA 4G0BA 1DPBA 2FY4A 2H3WA 5KJSA 1E2OA 5DUAA 2RKTA 1Q6XA 1EABA 2JGPA 2II3A 2I9DA 2E1TA 3U9BA 1XMDA 2FY3A 1EAFA 2FYOA 1CLAA 4JN5A 5DU9A 3U9FA 4KECA 4HVMA 2H3UA 2FY5A 2RKVA 5FALA 1T7NA 2CLAA 2IHWA 1NDFA
chains in the Genus database with same CATH topology
1DPDA 3B2SA 2II4A 1CIAA 5KJTA 1C4TA 2E1UA 1L5AA 3L60A 2FW3A 1NOCB 1NM8A 1S5OA 3CLAA 1NDIA 2H3PA 2H4TA 4KE4A 5KJVA 4N72A 1NDBA 1XL8A 1XL7A 2DEBA 2E1VA 1EAAA 5FANA 1EAEA 1XMCA 1EACA 4G2MA 2II5A 4CLAA 2BGHA 3FOTA 4EYWA 2XHGA 5KJWA 1Q23A 4EPHA 4EP9A 1DPCA 1Q9JA 1T7OA 2RCUA 5KJUA 2VSQA 4JN3A 1T7QA 1PD5A 1T1UA 3MAEA 2ZBAA 4G22A 2FY2A 3FP0A 5T3EA 2XR7A 1EADA 3B30A 1QCAA 1SCZA 4G0BA 1DPBA 2FY4A 2H3WA 5KJSA 1E2OA 5DUAA 2RKTA 1Q6XA 1EABA 2JGPA 2II3A 2I9DA 2E1TA 3U9BA 1XMDA 2FY3A 1EAFA 2FYOA 1CLAA 4JN5A 5DU9A 3U9FA 4KECA 4HVMA 2H3UA 2FY5A 2RKVA 5FALA 2CLAA 1T7NA 2IHWA 1NDFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DPB A;  2IHW A;  1DPD A;  3B2S A;  1XL8 A;  5KJS A;  1XL7 A;  2II4 A;  1DPC A;  1E2O A;  5DUA A;  1Q23 A;  1EAA A;  2E1V A;  5FAN A;  2RKT A;  1EAE A;  1XMC A;  1CIA A;  1EAB A;  1EAC A;  5KJT A;  4G2M A;  2JGP A;  1C4T A;  5KJU A;  2E1U A;  2VSQ A;  1L5A A;  4JN3 A;  2II3 A;  2I9D A;  2II5 A;  3L60 A;  2E1T A;  1PD5 A;  1NOC B;  3MAE A;  3U9B A;  4CLA A;  2BGH A;  1XMD A;  1EAF A;  2ZBA A;  4G22 A;  3FOT A;  1CLA A;  3FP0 A;  4JN5 A;  5DU9 A;  5T3E A;  2XR7 A;  1EAD A;  3U9F A;  3CLA A;  4KEC A;  2XHG A;  4HVM A;  3B30 A;  5KJW A;  2RKV A;  5FAL A;  2CLA A;  1QCA A;  4KE4 A;  5KJV A;  4N72 A;  1SCZ A;  1Q9J A;  4G0B A; 
#chains in the Genus database with same CATH topology
 1DPD A;  3B2S A;  2II4 A;  1CIA A;  5KJT A;  1C4T A;  2E1U A;  1L5A A;  3L60 A;  2FW3 A;  1NOC B;  1NM8 A;  1S5O A;  3CLA A;  1NDI A;  2H3P A;  2H4T A;  4KE4 A;  5KJV A;  4N72 A;  1NDB A;  1XL8 A;  1XL7 A;  2DEB A;  2E1V A;  1EAA A;  5FAN A;  1EAE A;  1XMC A;  1EAC A;  4G2M A;  2II5 A;  4CLA A;  2BGH A;  3FOT A;  4EYW A;  2XHG A;  5KJW A;  1Q23 A;  4EPH A;  4EP9 A;  1DPC A;  1Q9J A;  1T7O A;  2RCU A;  5KJU A;  2VSQ A;  4JN3 A;  1T7Q A;  1PD5 A;  1T1U A;  3MAE A;  2ZBA A;  2FY2 A;  4G22 A;  3FP0 A;  5T3E A;  2XR7 A;  1EAD A;  3B30 A;  1QCA A;  1SCZ A;  4G0B A;  1DPB A;  2FY4 A;  2H3W A;  5KJS A;  1E2O A;  5DUA A;  2RKT A;  1Q6X A;  1EAB A;  2JGP A;  2II3 A;  2I9D A;  2E1T A;  3U9B A;  1XMD A;  2FY3 A;  1EAF A;  2FYO A;  1CLA A;  4JN5 A;  5DU9 A;  3U9F A;  4KEC A;  4HVM A;  2H3U A;  2FY5 A;  2RKV A;  5FAL A;  1T7N A;  2CLA A;  2IHW A;  1NDF A; 
#chains in the Genus database with same CATH homology
 1DPD A;  3B2S A;  2II4 A;  1CIA A;  5KJT A;  1C4T A;  2E1U A;  1L5A A;  3L60 A;  2FW3 A;  1NOC B;  1NM8 A;  1S5O A;  3CLA A;  1NDI A;  2H3P A;  2H4T A;  4KE4 A;  5KJV A;  4N72 A;  1NDB A;  1XL8 A;  1XL7 A;  2DEB A;  2E1V A;  1EAA A;  5FAN A;  1EAE A;  1XMC A;  1EAC A;  4G2M A;  2II5 A;  4CLA A;  2BGH A;  3FOT A;  4EYW A;  2XHG A;  5KJW A;  1Q23 A;  4EPH A;  4EP9 A;  1DPC A;  1Q9J A;  1T7O A;  2RCU A;  5KJU A;  2VSQ A;  4JN3 A;  1T7Q A;  1PD5 A;  1T1U A;  3MAE A;  2ZBA A;  4G22 A;  2FY2 A;  3FP0 A;  5T3E A;  2XR7 A;  1EAD A;  3B30 A;  1QCA A;  1SCZ A;  4G0B A;  1DPB A;  2FY4 A;  2H3W A;  5KJS A;  1E2O A;  5DUA A;  2RKT A;  1Q6X A;  1EAB A;  2JGP A;  2II3 A;  2I9D A;  2E1T A;  3U9B A;  1XMD A;  2FY3 A;  1EAF A;  2FYO A;  1CLA A;  4JN5 A;  5DU9 A;  3U9F A;  4KEC A;  4HVM A;  2H3U A;  2FY5 A;  2RKV A;  5FAL A;  2CLA A;  1T7N A;  2IHW A;  1NDF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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