4JN3A

Crystal structures of the first condensation domain of the cda synthetase
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
446
structure length
446
Chain Sequence
NSSVRHGLTSAQHEVWLAQQLDPRGAHYRTGSCLEIDGPLDHAVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPEGSAAVEDPDGVPYTPVLLRHIDLSGHEDPEGEAQRWMDRDRATPLPLDRPGLSSHALFTLGGGRHLYYLGVHHIVIDGTSMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRAYWTGLFTDRPEPVSLTGRGGGRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIAGVAAFLHRTTGARDVVVSVPVTGRYGANARITPGMVSNRLPLRLAVRPGESFARVVETVSEAMSGLLAHSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLMRSISSGPTTDLNIVLTGTPESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAATVDEVALLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Biosynthetic protein
molecule keywords CDA peptide synthetase I
publication title Crystal Structures of the First Condensation Domain of CDA Synthetase Suggest Conformational Changes during the Synthetic Cycle of Nonribosomal Peptide Synthetases.
pubmed doi rcsb
source organism Streptomyces coelicolor
total genus 141
structure length 446
sequence length 446
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-03-14
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 4jn3A01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 4jn3A02
4G0BA 3U9BA 5KJVA 2VSQA 4JN3A 3FOTA 5FALA 4G22A 1DPCA 1Q23A 2I9DA 1Q9JA 5DU9A 2BGHA 1CIAA 2II3A 2XR7A 1EABA 3B2SA 3L60A 2RKTA 3MAEA 5T3EA 1CLAA 1DPBA 4N72A 2II5A 1EAEA 5KJSA 2CLAA 5KJTA 1C4TA 4HVMA 2E1VA 5KJUA 2E1UA 1SCZA 1L5AA 2II4A 5DUAA 5FANA 2E1TA 4JN5A 3U9FA 1EACA 1PD5A 1EADA 1DPDA 2IHWA 2XHGA 4KE4A 3B30A 4G2MA 1XL8A 2JGPA 2RKVA 1XMCA 1EAAA 2ZBAA 4CLAA 1E2OA 3FP0A 3CLAA 1XL7A 1XMDA 4KECA 1QCAA 1NOCB 1EAFA 5KJWA
chains in the Genus database with same CATH superfamily
4G0BA 3FOTA 2H3WA 2I9DA 1Q9JA 5DU9A 2BGHA 3B2SA 5T3EA 1T7QA 1EABA 1DPBA 4HVMA 2E1UA 1T1UA 4EPHA 2IHWA 1DPDA 2FYOA 4KE4A 1NM8A 2FW3A 4EP9A 2H3UA 2JGPA 1XMCA 2ZBAA 4CLAA 3CLAA 3U9BA 4JN3A 4G22A 5KJVA 1CIAA 2FY2A 2RKTA 3MAEA 2CLAA 5KJUA 2II4A 5DUAA 2FY4A 5FANA 4EYWA 1EACA 1PD5A 2H4TA 3FP0A 1XL7A 1QCAA 1NOCB 1S5OA 1DPCA 2II3A 2XR7A 1NDBA 3L60A 2DEBA 1CLAA 2H3PA 4N72A 1Q6XA 2FY5A 1SCZA 1L5AA 4JN5A 3U9FA 1NDIA 2XHGA 3B30A 1T7OA 1XMDA 1EAFA 2FY3A 2VSQA 1T7NA 5FALA 1Q23A 2II5A 1EAEA 5KJSA 5KJTA 1C4TA 2RCUA 2E1VA 2E1TA 1EADA 4G2MA 1XL8A 2RKVA 1EAAA 1E2OA 1NDFA 4KECA 5KJWA
chains in the Genus database with same CATH topology
4G0BA 3FOTA 2H3WA 2I9DA 1Q9JA 5DU9A 2BGHA 3B2SA 5T3EA 1T7QA 1EABA 1DPBA 4HVMA 2E1UA 1T1UA 4EPHA 2IHWA 1DPDA 2FYOA 4KE4A 1NM8A 2FW3A 4EP9A 2JGPA 2H3UA 1XMCA 2ZBAA 4CLAA 3CLAA 3U9BA 4JN3A 4G22A 5KJVA 1CIAA 2FY2A 2RKTA 3MAEA 2CLAA 5KJUA 2II4A 5DUAA 2FY4A 5FANA 4EYWA 1EACA 1PD5A 2H4TA 3FP0A 1XL7A 1QCAA 1NOCB 1S5OA 1DPCA 2II3A 2XR7A 1NDBA 3L60A 2DEBA 1CLAA 4N72A 2H3PA 1Q6XA 1L5AA 1SCZA 2FY5A 4JN5A 3U9FA 1NDIA 2XHGA 3B30A 1T7OA 1XMDA 1EAFA 2FY3A 2VSQA 1T7NA 5FALA 1Q23A 2II5A 1EAEA 5KJSA 5KJTA 1C4TA 2RCUA 2E1VA 2E1TA 1EADA 4G2MA 1XL8A 2RKVA 1EAAA 1E2OA 1NDFA 4KECA 5KJWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G0B A;  3U9B A;  5KJV A;  2VSQ A;  4JN3 A;  3FOT A;  5FAL A;  4G22 A;  1DPC A;  1Q23 A;  2I9D A;  1Q9J A;  5DU9 A;  2BGH A;  1CIA A;  2II3 A;  2XR7 A;  1EAB A;  3B2S A;  3L60 A;  2RKT A;  3MAE A;  5T3E A;  1CLA A;  1DPB A;  4N72 A;  2II5 A;  1EAE A;  5KJS A;  2CLA A;  5KJT A;  1C4T A;  4HVM A;  2E1V A;  5KJU A;  2E1U A;  1SCZ A;  1L5A A;  2II4 A;  5DUA A;  5FAN A;  2E1T A;  4JN5 A;  3U9F A;  1EAC A;  1PD5 A;  1EAD A;  1DPD A;  2IHW A;  2XHG A;  4KE4 A;  3B30 A;  4G2M A;  1XL8 A;  2JGP A;  2RKV A;  1XMC A;  1EAA A;  2ZBA A;  4CLA A;  1E2O A;  3FP0 A;  3CLA A;  1XL7 A;  1XMD A;  4KEC A;  1QCA A;  1NOC B;  1EAF A;  5KJW A; 
#chains in the Genus database with same CATH topology
 4G0B A;  3FOT A;  2H3W A;  2I9D A;  1Q9J A;  5DU9 A;  2BGH A;  3B2S A;  5T3E A;  1T7Q A;  1EAB A;  1DPB A;  4HVM A;  2E1U A;  1T1U A;  4EPH A;  2IHW A;  1DPD A;  2FYO A;  4KE4 A;  1NM8 A;  2FW3 A;  4EP9 A;  2H3U A;  2JGP A;  1XMC A;  2ZBA A;  4CLA A;  3CLA A;  3U9B A;  4JN3 A;  4G22 A;  5KJV A;  1CIA A;  2FY2 A;  2RKT A;  3MAE A;  2CLA A;  5KJU A;  2II4 A;  5DUA A;  2FY4 A;  5FAN A;  4EYW A;  1EAC A;  1PD5 A;  2H4T A;  3FP0 A;  1XL7 A;  1QCA A;  1NOC B;  1S5O A;  1DPC A;  2II3 A;  2XR7 A;  1NDB A;  3L60 A;  2DEB A;  1CLA A;  2H3P A;  4N72 A;  1Q6X A;  2FY5 A;  1SCZ A;  1L5A A;  4JN5 A;  3U9F A;  1NDI A;  2XHG A;  3B30 A;  1T7O A;  1XMD A;  1EAF A;  2FY3 A;  2VSQ A;  1T7N A;  5FAL A;  1Q23 A;  2II5 A;  1EAE A;  5KJS A;  5KJT A;  1C4T A;  2RCU A;  2E1V A;  2E1T A;  1EAD A;  4G2M A;  1XL8 A;  2RKV A;  1EAA A;  1E2O A;  1NDF A;  4KEC A;  5KJW A; 
#chains in the Genus database with same CATH homology
 4G0B A;  3FOT A;  2H3W A;  2I9D A;  1Q9J A;  5DU9 A;  2BGH A;  3B2S A;  5T3E A;  1T7Q A;  1EAB A;  1DPB A;  4HVM A;  2E1U A;  1T1U A;  4EPH A;  2IHW A;  1DPD A;  2FYO A;  4KE4 A;  1NM8 A;  2FW3 A;  4EP9 A;  2JGP A;  2H3U A;  1XMC A;  2ZBA A;  4CLA A;  3CLA A;  3U9B A;  4JN3 A;  4G22 A;  5KJV A;  1CIA A;  2FY2 A;  2RKT A;  3MAE A;  2CLA A;  5KJU A;  2II4 A;  5DUA A;  2FY4 A;  5FAN A;  4EYW A;  1EAC A;  1PD5 A;  2H4T A;  3FP0 A;  1XL7 A;  1QCA A;  1NOC B;  1S5O A;  1DPC A;  2II3 A;  2XR7 A;  1NDB A;  3L60 A;  2DEB A;  1CLA A;  4N72 A;  2H3P A;  1Q6X A;  1L5A A;  1SCZ A;  2FY5 A;  4JN5 A;  3U9F A;  1NDI A;  2XHG A;  3B30 A;  1T7O A;  1XMD A;  1EAF A;  2FY3 A;  2VSQ A;  1T7N A;  5FAL A;  1Q23 A;  2II5 A;  1EAE A;  5KJS A;  5KJT A;  1C4T A;  2RCU A;  2E1V A;  2E1T A;  1EAD A;  4G2M A;  1XL8 A;  2RKV A;  1EAA A;  1E2O A;  1NDF A;  4KEC A;  5KJW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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