1EABA

Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
243
structure length
243
Chain Sequence
IPPIPPVDFAKYGEIEEVPMTRLMQIGATNLHRSWLNVPHVTQFESADITELEAFRVAQKAVAKKAGVKLTVLPLLLKACAYLLKELPDFNSSLAPSGQALIRKKYVHIGFAVDTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGACFTISSLGHIGGTAFTPIVNAPEVAILGVSKASMQPVWDGKAFQPRLMLPLSLSYDHRVINGAAAARFTKRLGDLLADIRAILL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
pubmed doi rcsb
molecule tags Dihydrolipoamide acetyltransferase
source organism Azotobacter vinelandii
molecule keywords DIHYDROLIPOYL-TRANSACETYLASE
total genus 68
structure length 243
sequence length 243
ec nomenclature ec 2.3.1.12: Dihydrolipoyllysine-residue acetyltransferase.
pdb deposition date 1992-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 1eabA00
4G0BA 1EAAA 4JN3A 1CLAA 1XMCA 3B2SA 3FOTA 2II3A 2RKTA 4KE4A 3U9BA 4CLAA 2E1VA 3CLAA 4G2MA 2VSQA 1SCZA 4KECA 3MAEA 1DPDA 1EACA 5KJWA 1XMDA 5KJUA 4HVMA 1NOCB 3U9FA 4JN5A 1Q9JA 3B30A 1DPBA 1XL8A 1QCAA 5KJVA 1PD5A 1CIAA 2E1UA 2XHGA 2XR7A 4N72A 5DU9A 1C4TA 1XL7A 1EAEA 2I9DA 2IHWA 5T3EA 1Q23A 3FP0A 1L5AA 5KJTA 1DPCA 3L60A 5KJSA 2BGHA 2ZBAA 2II5A 4G22A 2CLAA 2II4A 5FANA 5FALA 1EADA 5DUAA 1EABA 1EAFA 2RKVA 2JGPA 2E1TA 1E2OA
chains in the Genus database with same CATH superfamily
2FY2A 4KE4A 2E1VA 5KJWA 1DPDA 4HVMA 1NDBA 1DPBA 1QCAA 2H3PA 4N72A 2DEBA 1C4TA 5T3EA 1L5AA 3FP0A 3L60A 5KJSA 2H4TA 1EADA 1EAAA 4JN3A 3B2SA 3FOTA 2FY4A 4G2MA 1SCZA 1NDIA 5KJVA 2XHGA 1XL7A 2I9DA 2IHWA 1T7NA 2II5A 5FANA 2JGPA 1NM8A 1S5OA 2RCUA 4EP9A 2RKTA 3U9BA 4CLAA 2VSQA 3MAEA 1EACA 5KJUA 1NOCB 1T7QA 2H3UA 1CIAA 1NDFA 2E1UA 2FYOA 2XR7A 5DU9A 2FY5A 1T1UA 5KJTA 2BGHA 2ZBAA 4G22A 2II4A 5DUAA 1EABA 2RKVA 1E2OA 4G0BA 1CLAA 1XMCA 2II3A 3CLAA 1T7OA 4KECA 1XMDA 4EYWA 3U9FA 1Q6XA 4JN5A 1Q9JA 3B30A 1XL8A 4EPHA 1PD5A 2FW3A 1EAEA 1Q23A 2H3WA 1DPCA 2FY3A 2CLAA 5FALA 1EAFA 2E1TA
chains in the Genus database with same CATH topology
4G0BA 1EAAA 4JN3A 1CLAA 1XMCA 3B2SA 3FOTA 2II3A 2RKTA 4KE4A 3U9BA 4CLAA 2E1VA 3CLAA 4G2MA 2VSQA 1SCZA 4KECA 3MAEA 1DPDA 1EACA 5KJWA 1XMDA 5KJUA 4HVMA 1NOCB 3U9FA 4JN5A 1Q9JA 3B30A 1DPBA 1XL8A 1QCAA 5KJVA 1PD5A 1CIAA 2E1UA 2XHGA 2XR7A 4N72A 5DU9A 1C4TA 1XL7A 1EAEA 2I9DA 2IHWA 5T3EA 1Q23A 3FP0A 1L5AA 5KJTA 1DPCA 3L60A 5KJSA 2BGHA 2ZBAA 2II5A 4G22A 2CLAA 2II4A 5FANA 5FALA 1EADA 5DUAA 1EABA 1EAFA 2RKVA 2JGPA 2E1TA 1E2OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G0B A;  1EAA A;  4JN3 A;  1CLA A;  1XMC A;  3B2S A;  3FOT A;  2II3 A;  2RKT A;  4KE4 A;  3U9B A;  4CLA A;  2E1V A;  3CLA A;  4G2M A;  2VSQ A;  1SCZ A;  4KEC A;  3MAE A;  1DPD A;  1EAC A;  5KJW A;  1XMD A;  5KJU A;  4HVM A;  1NOC B;  3U9F A;  4JN5 A;  1Q9J A;  3B30 A;  1DPB A;  1XL8 A;  1QCA A;  5KJV A;  1PD5 A;  1CIA A;  2E1U A;  2XHG A;  2XR7 A;  4N72 A;  5DU9 A;  1C4T A;  1XL7 A;  1EAE A;  2I9D A;  2IHW A;  5T3E A;  1Q23 A;  3FP0 A;  1L5A A;  5KJT A;  1DPC A;  3L60 A;  5KJS A;  2BGH A;  2ZBA A;  2II5 A;  4G22 A;  2CLA A;  2II4 A;  5FAN A;  5FAL A;  1EAD A;  5DUA A;  1EAB A;  1EAF A;  2RKV A;  2JGP A;  2E1T A;  1E2O A; 
#chains in the Genus database with same CATH topology
 2FY2 A;  4KE4 A;  2E1V A;  5KJW A;  1DPD A;  4HVM A;  1NDB A;  1DPB A;  1QCA A;  2H3P A;  4N72 A;  2DEB A;  1C4T A;  5T3E A;  1L5A A;  3FP0 A;  3L60 A;  5KJS A;  2H4T A;  1EAD A;  1EAA A;  4JN3 A;  3B2S A;  3FOT A;  2FY4 A;  4G2M A;  1SCZ A;  1NDI A;  5KJV A;  2XHG A;  1XL7 A;  2I9D A;  2IHW A;  1T7N A;  2II5 A;  5FAN A;  2JGP A;  1NM8 A;  1S5O A;  2RCU A;  4EP9 A;  2RKT A;  3U9B A;  4CLA A;  2VSQ A;  3MAE A;  1EAC A;  5KJU A;  1NOC B;  1T7Q A;  2H3U A;  1CIA A;  1NDF A;  2E1U A;  2FYO A;  2XR7 A;  5DU9 A;  2FY5 A;  1T1U A;  5KJT A;  2BGH A;  2ZBA A;  4G22 A;  2II4 A;  5DUA A;  1EAB A;  2RKV A;  1E2O A;  4G0B A;  1CLA A;  1XMC A;  2II3 A;  3CLA A;  1T7O A;  4KEC A;  1XMD A;  4EYW A;  3U9F A;  1Q6X A;  4JN5 A;  1Q9J A;  3B30 A;  1XL8 A;  4EPH A;  1PD5 A;  2FW3 A;  1EAE A;  1Q23 A;  2H3W A;  1DPC A;  2FY3 A;  2CLA A;  5FAL A;  1EAF A;  2E1T A; 
#chains in the Genus database with same CATH homology
 4G0B A;  1EAA A;  4JN3 A;  1CLA A;  1XMC A;  3B2S A;  3FOT A;  2II3 A;  2RKT A;  4KE4 A;  3U9B A;  4CLA A;  2E1V A;  3CLA A;  4G2M A;  2VSQ A;  1SCZ A;  4KEC A;  3MAE A;  1DPD A;  1EAC A;  5KJW A;  1XMD A;  5KJU A;  4HVM A;  1NOC B;  3U9F A;  4JN5 A;  1Q9J A;  3B30 A;  1DPB A;  1XL8 A;  1QCA A;  5KJV A;  1PD5 A;  1CIA A;  2E1U A;  2XHG A;  2XR7 A;  4N72 A;  5DU9 A;  1C4T A;  1XL7 A;  1EAE A;  2I9D A;  2IHW A;  5T3E A;  1Q23 A;  3FP0 A;  1L5A A;  5KJT A;  1DPC A;  3L60 A;  5KJS A;  2BGH A;  2ZBA A;  2II5 A;  4G22 A;  2CLA A;  2II4 A;  5FAN A;  5FAL A;  1EAD A;  5DUA A;  1EAB A;  1EAF A;  2RKV A;  2JGP A;  2E1T A;  1E2O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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