2H3WA

Crystal structure of the s554a/m564g mutant of murine carnitine acetyltransferase in complex with hexanoylcarnitine and coa
Total Genus 218
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
599
structure length
599
Chain Sequence
SHMAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTAQVPAKTDCVGFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords carnitine acetyltransferase
publication title Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates
pubmed doi rcsb
source organism Mus musculus
total genus 218
structure length 599
sequence length 599
chains with identical sequence B
ec nomenclature ec 2.3.1.7: Carnitine O-acetyltransferase.
pdb deposition date 2006-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00755 Carn_acyltransf Choline/Carnitine o-acyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.40 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 2h3wA01
3.30.559.70 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 2h3wA02
2H3UA 2FY3A 4EPHA 2DEBA 1T7QA 4EYWA 2FY2A 2RCUA 2H3PA 2H4TA 1Q6XA 1T1UA 1NM8A 1T7NA 1NDBA 1NDIA 1T7OA 4EP9A 2H3WA 1S5OA 2FYOA 2FY5A 1NDFA 2FY4A 2FW3A
chains in the Genus database with same CATH superfamily
1EAAA 4EPHA 4N72A 1E2OA 2RCUA 5DU9A 1XL8A 1SCZA 1T1UA 2II4A 2E1VA 3U9BA 3B2SA 1EAEA 1NDIA 1QCAA 4JN3A 4HVMA 3FOTA 4G0BA 4EP9A 1Q23A 2FY3A 1EAFA 2II3A 1C4TA 1Q9JA 2FY2A 5KJSA 2H3PA 5FALA 1EABA 1DPDA 1L5AA 2RKTA 5KJTA 3L60A 1Q6XA 1NM8A 2IHWA 1T7NA 1CIAA 3MAEA 4KE4A 2RKVA 3CLAA 1T7OA 1EACA 2E1TA 1S5OA 2II5A 1PD5A 2CLAA 1NDFA 4CLAA 2FW3A 5KJVA 1EADA 4EYWA 2XR7A 5T3EA 1XMCA 1CLAA 3U9FA 3B30A 2XHGA 4JN5A 2FYOA 3FP0A 4KECA 2FY5A 5FANA 2H3UA 5KJWA 5DUAA 2DEBA 1T7QA 2E1UA 1XL7A 2H4TA 4G2MA 4G22A 1NDBA 1DPBA 2VSQA 2I9DA 2H3WA 1DPCA 2ZBAA 1NOCB 2JGPA 1XMDA 2BGHA 5KJUA 2FY4A
chains in the Genus database with same CATH topology
2H3UA 2FY3A 5DUAA 4EPHA 2DEBA 1T7QA 4EYWA 1Q9JA 2FY2A 2RCUA 2H3PA 5T3EA 5DU9A 1L5AA 2H4TA 1Q6XA 1T1UA 1NM8A 1T7NA 2XHGA 1NDBA 1NDIA 2VSQA 4JN3A 1T7OA 4EP9A 2H3WA 4HVMA 4JN5A 3FOTA 2JGPA 1S5OA 2FYOA 3FP0A 2FY5A 1NDFA 2FY4A 2FW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H3U A;  2FY3 A;  4EPH A;  2DEB A;  1T7Q A;  4EYW A;  2FY2 A;  2RCU A;  2H3P A;  2H4T A;  1Q6X A;  1T1U A;  1NM8 A;  1T7N A;  1NDB A;  1NDI A;  1T7O A;  4EP9 A;  2H3W A;  1S5O A;  2FYO A;  2FY5 A;  1NDF A;  2FY4 A;  2FW3 A; 
#chains in the Genus database with same CATH topology
 1EAA A;  4EPH A;  4N72 A;  1E2O A;  2RCU A;  5DU9 A;  1XL8 A;  1SCZ A;  1T1U A;  2II4 A;  2E1V A;  3U9B A;  3B2S A;  1EAE A;  1NDI A;  1QCA A;  4JN3 A;  4HVM A;  3FOT A;  4G0B A;  4EP9 A;  1Q23 A;  2FY3 A;  1EAF A;  2II3 A;  1C4T A;  1Q9J A;  2FY2 A;  5KJS A;  2H3P A;  5FAL A;  1EAB A;  1DPD A;  1L5A A;  2RKT A;  5KJT A;  3L60 A;  1Q6X A;  1NM8 A;  2IHW A;  1T7N A;  1CIA A;  3MAE A;  4KE4 A;  2RKV A;  3CLA A;  1T7O A;  1EAC A;  2E1T A;  1S5O A;  2II5 A;  1PD5 A;  2CLA A;  1NDF A;  4CLA A;  2FW3 A;  5KJV A;  1EAD A;  4EYW A;  2XR7 A;  5T3E A;  1XMC A;  1CLA A;  3U9F A;  3B30 A;  2XHG A;  4JN5 A;  2FYO A;  3FP0 A;  4KEC A;  2FY5 A;  5FAN A;  2H3U A;  5KJW A;  5DUA A;  2DEB A;  1T7Q A;  2E1U A;  1XL7 A;  2H4T A;  4G2M A;  4G22 A;  1NDB A;  1DPB A;  2VSQ A;  2I9D A;  2H3W A;  1DPC A;  2ZBA A;  1NOC B;  2JGP A;  1XMD A;  2BGH A;  5KJU A;  2FY4 A; 
#chains in the Genus database with same CATH homology
 2H3U A;  2FY3 A;  5DUA A;  4EPH A;  2DEB A;  1T7Q A;  4EYW A;  1Q9J A;  2FY2 A;  2RCU A;  2H3P A;  5T3E A;  5DU9 A;  1L5A A;  2H4T A;  1Q6X A;  1T1U A;  1NM8 A;  1T7N A;  2XHG A;  1NDB A;  1NDI A;  2VSQ A;  4JN3 A;  1T7O A;  4EP9 A;  2H3W A;  4HVM A;  4JN5 A;  3FOT A;  2JGP A;  1S5O A;  2FYO A;  3FP0 A;  2FY5 A;  1NDF A;  2FY4 A;  2FW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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