2H3WA

Crystal structure of the s554a/m564g mutant of murine carnitine acetyltransferase in complex with hexanoylcarnitine and coa
Total Genus 218
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
218
sequence length
599
structure length
599
Chain Sequence
SHMAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTAQVPAKTDCVGFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords carnitine acetyltransferase
publication title Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates
pubmed doi rcsb
source organism Mus musculus
molecule tags Transferase
total genus 218
structure length 599
sequence length 599
chains with identical sequence B
ec nomenclature ec 2.3.1.7: Carnitine O-acetyltransferase.
pdb deposition date 2006-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00755 Carn_acyltransf Choline/Carnitine o-acyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.40 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 2h3wA01
3.30.559.70 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 2h3wA02
1T7NA 4EYWA 1S5OA 1T1UA 2H3UA 4EPHA 2FY5A 2FY4A 2FY3A 2H3WA 2FYOA 1Q6XA 1T7OA 2FW3A 1NDIA 1T7QA 1NDBA 2H4TA 2DEBA 2H3PA 2FY2A 4EP9A 1NDFA 2RCUA 1NM8A
chains in the Genus database with same CATH superfamily
4EYWA 1DPDA 4HVMA 1T1UA 2H3UA 1EACA 2FY4A 2XR7A 2JGPA 4G0BA 2FY3A 2RKTA 1E2OA 2FYOA 4N72A 5T3EA 1EADA 1Q6XA 5KJUA 5KJVA 2E1VA 4EP9A 4G22A 1NDFA 3FP0A 2I9DA 1CIAA 1L5AA 1S5OA 3B2SA 2RKVA 4EPHA 4KECA 2FY5A 5FALA 5DUAA 1XMCA 1Q23A 1T7OA 2FW3A 2II3A 1XL8A 4CLAA 5KJWA 2H3PA 4JN3A 1C4TA 2BGHA 2RCUA 4KE4A 1T7NA 5DU9A 1EABA 3B30A 2II5A 2E1TA 1NDIA 2II4A 2ZBAA 3CLAA 1NDBA 2H4TA 2DEBA 3U9FA 2FY2A 3L60A 3U9BA 1CLAA 2CLAA 3FOTA 1EAAA 4G2MA 1XL7A 4JN5A 5FANA 2IHWA 5KJTA 1EAFA 1SCZA 1XMDA 2H3WA 2XHGA 1PD5A 2VSQA 1NOCB 1EAEA 5KJSA 1T7QA 1QCAA 2E1UA 1DPCA 1Q9JA 3MAEA 1DPBA 1NM8A
chains in the Genus database with same CATH topology
1T7NA 1L5AA 4EYWA 4HVMA 1S5OA 1T1UA 4JN5A 2H3UA 5DU9A 4EPHA 2FY5A 2FY4A 2JGPA 5DUAA 2FY3A 2H3WA 2XHGA 2VSQA 2FYOA 5T3EA 1Q6XA 1T7OA 2FW3A 1NDIA 1T7QA 1NDBA 2H4TA 2DEBA 2H3PA 2FY2A 4JN3A 4EP9A 1Q9JA 1NDFA 3FP0A 3FOTA 2RCUA 1NM8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T7N A;  4EYW A;  1S5O A;  1T1U A;  2H3U A;  4EPH A;  2FY5 A;  2FY4 A;  2FY3 A;  2H3W A;  2FYO A;  1Q6X A;  1T7O A;  2FW3 A;  1NDI A;  1T7Q A;  1NDB A;  2H4T A;  2DEB A;  2H3P A;  2FY2 A;  4EP9 A;  1NDF A;  2RCU A;  1NM8 A; 
#chains in the Genus database with same CATH topology
 4EYW A;  1DPD A;  4HVM A;  1T1U A;  2H3U A;  1EAC A;  2FY4 A;  2XR7 A;  2JGP A;  4G0B A;  2FY3 A;  2RKT A;  1E2O A;  2FYO A;  4N72 A;  5T3E A;  1EAD A;  1Q6X A;  5KJU A;  5KJV A;  2E1V A;  4EP9 A;  4G22 A;  1NDF A;  3FP0 A;  2I9D A;  1CIA A;  1L5A A;  1S5O A;  3B2S A;  2RKV A;  4EPH A;  4KEC A;  2FY5 A;  5FAL A;  5DUA A;  1XMC A;  1Q23 A;  1T7O A;  2FW3 A;  2II3 A;  1XL8 A;  4CLA A;  5KJW A;  2H3P A;  4JN3 A;  1C4T A;  2BGH A;  2RCU A;  4KE4 A;  1T7N A;  5DU9 A;  1EAB A;  3B30 A;  2II5 A;  2E1T A;  1NDI A;  2II4 A;  2ZBA A;  3CLA A;  1NDB A;  2H4T A;  2DEB A;  3U9F A;  2FY2 A;  3L60 A;  3U9B A;  1CLA A;  2CLA A;  3FOT A;  1EAA A;  4G2M A;  1XL7 A;  4JN5 A;  5FAN A;  2IHW A;  5KJT A;  1EAF A;  1SCZ A;  1XMD A;  2H3W A;  2XHG A;  1PD5 A;  2VSQ A;  1NOC B;  1EAE A;  5KJS A;  1T7Q A;  1QCA A;  2E1U A;  1DPC A;  1Q9J A;  3MAE A;  1DPB A;  1NM8 A; 
#chains in the Genus database with same CATH homology
 1T7N A;  1L5A A;  4EYW A;  4HVM A;  1S5O A;  1T1U A;  4JN5 A;  2H3U A;  5DU9 A;  4EPH A;  2FY5 A;  2FY4 A;  2JGP A;  5DUA A;  2FY3 A;  2H3W A;  2XHG A;  2VSQ A;  2FYO A;  5T3E A;  1Q6X A;  1T7O A;  2FW3 A;  1NDI A;  1T7Q A;  1NDB A;  2H4T A;  2DEB A;  2H3P A;  2FY2 A;  4JN3 A;  4EP9 A;  1Q9J A;  1NDF A;  3FP0 A;  3FOT A;  2RCU A;  1NM8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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