1QCAA

Quadruple mutant q92c, n146f, y168f, i172v type iii cat complexed with fusidic acid. crystals grown at ph 6.3. x-ray data collected at room temperature
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
213
structure length
211
Chain Sequence
MNYTKFDVKNWVRREHFEFYRHRLPCGFSLTSKIDITTLKKSLDDSAYKFYPVMIYLIAQAVNQFDELRMAIKDDELIVWDSVDPCFTVFHQETETFSALSCPYSSDIDQFMVNYLSVMERYKSDTKLFPQGPENHLFISALPWVNFDSFNLNVANFTDFFAPVITMAKYQQEGDRLLLPLSVQVHHAVCDGFHVARFINRLQELCNSKLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Steroid recognition by chloramphenicol acetyltransferase: engineering and structural analysis of a high affinity fusidic acid binding site.
pubmed doi rcsb
molecule tags Transferase (acyltransferase)
source organism Shigella flexneri
molecule keywords TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE
total genus 55
structure length 211
sequence length 213
ec nomenclature ec 2.3.1.28: Chloramphenicol O-acetyltransferase.
pdb deposition date 1995-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00302 CAT Chloramphenicol acetyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 1qcaA00
3FP0A 4G22A 2II3A 4CLAA 1EAEA 2RKTA 5DU9A 1CIAA 4JN3A 4HVMA 1E2OA 2E1TA 5KJVA 2II5A 5FALA 5KJUA 2I9DA 2XHGA 4G0BA 1XMCA 1Q23A 1C4TA 2IHWA 4N72A 5KJTA 2RKVA 1XL7A 2JGPA 2E1VA 1L5AA 3U9FA 3U9BA 4KECA 1SCZA 1Q9JA 1QCAA 1EAAA 2BGHA 1EAFA 1NOCB 1DPBA 1CLAA 1DPCA 1XL8A 2ZBAA 2VSQA 1EACA 3FOTA 3MAEA 4G2MA 5KJWA 1EADA 4KE4A 1PD5A 3B30A 4JN5A 3B2SA 5DUAA 2II4A 1EABA 1XMDA 3L60A 5FANA 3CLAA 5KJSA 2XR7A 1DPDA 2E1UA 2CLAA 5T3EA
chains in the Genus database with same CATH superfamily
4CLAA 2II3A 5DU9A 2FY5A 4JN3A 4HVMA 5FALA 2I9DA 1Q23A 2IHWA 1XL7A 1L5AA 1T7QA 4KECA 1T7NA 2ZBAA 4EP9A 2FY2A 2II4A 3CLAA 1DPDA 2E1UA 5T3EA 5KJVA 2XHGA 2RKVA 1S5OA 2DEBA 2JGPA 2E1VA 4EYWA 3U9BA 1Q9JA 1EAAA 1CLAA 2H3PA 4G2MA 1EADA 4KE4A 1PD5A 1NDFA 1NM8A 4JN5A 1XMDA 1T7OA 3L60A 2II5A 2CLAA 2FY3A 2RKTA 2H3WA 1E2OA 2FY4A 5KJUA 2H4TA 1XMCA 1NDBA 3U9FA 4EPHA 2RCUA 1QCAA 2BGHA 1EAFA 1NOCB 2FW3A 5KJWA 1EACA 1NDIA 3B30A 2FYOA 3B2SA 5FANA 3FP0A 4G22A 1EAEA 1T1UA 1CIAA 1Q6XA 2E1TA 4G0BA 1C4TA 4N72A 1SCZA 2H3UA 1DPBA 1XL8A 1DPCA 3FOTA 2VSQA 3MAEA 5DUAA 1EABA 5KJSA 2XR7A 5KJTA
chains in the Genus database with same CATH topology
3FP0A 4G22A 2II3A 4CLAA 1EAEA 2RKTA 5DU9A 1CIAA 4JN3A 4HVMA 1E2OA 2E1TA 5KJVA 2II5A 5FALA 5KJUA 2I9DA 2XHGA 4G0BA 1XMCA 1Q23A 1C4TA 2IHWA 4N72A 5KJTA 2RKVA 1XL7A 2JGPA 2E1VA 1L5AA 3U9FA 3U9BA 4KECA 1SCZA 1Q9JA 1QCAA 1EAAA 2BGHA 1EAFA 1NOCB 1DPBA 1CLAA 1DPCA 1XL8A 2ZBAA 2VSQA 1EACA 3FOTA 3MAEA 4G2MA 5KJWA 1EADA 4KE4A 1PD5A 3B30A 4JN5A 3B2SA 5DUAA 2II4A 1EABA 1XMDA 3L60A 5FANA 3CLAA 5KJSA 2XR7A 1DPDA 2E1UA 2CLAA 5T3EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FP0 A;  4G22 A;  2II3 A;  4CLA A;  1EAE A;  2RKT A;  5DU9 A;  1CIA A;  4JN3 A;  4HVM A;  1E2O A;  2E1T A;  5KJV A;  2II5 A;  5FAL A;  5KJU A;  2I9D A;  2XHG A;  4G0B A;  1XMC A;  1Q23 A;  1C4T A;  2IHW A;  4N72 A;  5KJT A;  2RKV A;  1XL7 A;  2JGP A;  2E1V A;  1L5A A;  3U9F A;  3U9B A;  4KEC A;  1SCZ A;  1Q9J A;  1QCA A;  1EAA A;  2BGH A;  1EAF A;  1NOC B;  1DPB A;  1CLA A;  1DPC A;  1XL8 A;  2ZBA A;  2VSQ A;  1EAC A;  3FOT A;  3MAE A;  4G2M A;  5KJW A;  1EAD A;  4KE4 A;  1PD5 A;  3B30 A;  4JN5 A;  3B2S A;  5DUA A;  2II4 A;  1EAB A;  1XMD A;  3L60 A;  5FAN A;  3CLA A;  5KJS A;  2XR7 A;  1DPD A;  2E1U A;  2CLA A;  5T3E A; 
#chains in the Genus database with same CATH topology
 4CLA A;  2II3 A;  5DU9 A;  2FY5 A;  4JN3 A;  4HVM A;  5FAL A;  2I9D A;  1Q23 A;  2IHW A;  1XL7 A;  1L5A A;  1T7Q A;  4KEC A;  1T7N A;  2ZBA A;  4EP9 A;  2FY2 A;  2II4 A;  3CLA A;  1DPD A;  2E1U A;  5T3E A;  5KJV A;  2XHG A;  2RKV A;  1S5O A;  2DEB A;  2JGP A;  2E1V A;  4EYW A;  3U9B A;  1Q9J A;  1EAA A;  1CLA A;  2H3P A;  4G2M A;  1EAD A;  4KE4 A;  1PD5 A;  1NDF A;  1NM8 A;  4JN5 A;  1XMD A;  1T7O A;  3L60 A;  2II5 A;  2CLA A;  2FY3 A;  2RKT A;  2H3W A;  1E2O A;  2FY4 A;  5KJU A;  2H4T A;  1XMC A;  1NDB A;  3U9F A;  4EPH A;  2RCU A;  1QCA A;  2BGH A;  1EAF A;  1NOC B;  2FW3 A;  5KJW A;  1EAC A;  1NDI A;  3B30 A;  2FYO A;  3B2S A;  5FAN A;  3FP0 A;  4G22 A;  1EAE A;  1T1U A;  1CIA A;  1Q6X A;  2E1T A;  4G0B A;  1C4T A;  4N72 A;  1SCZ A;  2H3U A;  1DPB A;  1XL8 A;  1DPC A;  3FOT A;  2VSQ A;  3MAE A;  5DUA A;  1EAB A;  5KJS A;  2XR7 A;  5KJT A; 
#chains in the Genus database with same CATH homology
 3FP0 A;  4G22 A;  2II3 A;  4CLA A;  1EAE A;  2RKT A;  5DU9 A;  1CIA A;  4JN3 A;  4HVM A;  1E2O A;  2E1T A;  5KJV A;  2II5 A;  5FAL A;  5KJU A;  2I9D A;  2XHG A;  4G0B A;  1XMC A;  1Q23 A;  1C4T A;  2IHW A;  4N72 A;  5KJT A;  2RKV A;  1XL7 A;  2JGP A;  2E1V A;  1L5A A;  3U9F A;  3U9B A;  4KEC A;  1SCZ A;  1Q9J A;  1QCA A;  1EAA A;  2BGH A;  1EAF A;  1NOC B;  1DPB A;  1CLA A;  1DPC A;  1XL8 A;  2ZBA A;  2VSQ A;  1EAC A;  3FOT A;  3MAE A;  4G2M A;  5KJW A;  1EAD A;  4KE4 A;  1PD5 A;  3B30 A;  4JN5 A;  3B2S A;  5DUA A;  2II4 A;  1EAB A;  1XMD A;  3L60 A;  5FAN A;  3CLA A;  5KJS A;  2XR7 A;  1DPD A;  2E1U A;  2CLA A;  5T3E A; 
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