1T7OA

Crystal structure of the m564g mutant of murine carnitine acetyltransferase in complex with carnitine
Total Genus 214
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
214
sequence length
599
structure length
599
Chain Sequence
SHMAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVGFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Carnitine acetyltransferase
publication title Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase
pubmed doi rcsb
source organism Mus musculus
total genus 214
structure length 599
sequence length 599
ec nomenclature ec 2.3.1.7: Carnitine O-acetyltransferase.
pdb deposition date 2004-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00755 Carn_acyltransf Choline/Carnitine o-acyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.40 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1t7oA01
3.30.559.70 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1t7oA02
1T1UA 4EPHA 2FY3A 2H4TA 2FYOA 2H3UA 2FW3A 2H3WA 1NDIA 1NM8A 1T7NA 2DEBA 2FY4A 2FY2A 2FY5A 1S5OA 4EYWA 2H3PA 2RCUA 1T7OA 1NDBA 1T7QA 1NDFA 4EP9A 1Q6XA
chains in the Genus database with same CATH superfamily
5FALA 2H4TA 2FYOA 4KE4A 1NM8A 2XHGA 1NOCB 2E1TA 1XMDA 2DEBA 1EADA 2FY4A 2JGPA 5KJUA 4JN3A 1NDBA 1Q9JA 1C4TA 1T7QA 5KJTA 3CLAA 4EP9A 5DUAA 2VSQA 1Q6XA 4CLAA 4EPHA 4HVMA 3B30A 4JN5A 1NDIA 2BGHA 3U9BA 1XMCA 2IHWA 1T7NA 1PD5A 1CIAA 2FY2A 3L60A 2RCUA 5FANA 2ZBAA 2E1VA 2II3A 2RKTA 1Q23A 5DU9A 1EAEA 1T1UA 5KJSA 2FW3A 1XL8A 2II4A 1EABA 1S5OA 1XL7A 2H3PA 1T7OA 4N72A 3FOTA 1QCAA 1NDFA 3FP0A 1EAFA 1DPCA 1DPBA 3B2SA 2II5A 1L5AA 2FY3A 1EAAA 2CLAA 4G2MA 2H3UA 4KECA 2H3WA 2I9DA 2FY5A 4EYWA 1E2OA 5T3EA 2XR7A 1CLAA 3MAEA 4G0BA 2E1UA 5KJWA 1EACA 1DPDA 1SCZA 2RKVA 4G22A 5KJVA 3U9FA
chains in the Genus database with same CATH topology
1T1UA 4EPHA 2FY3A 4HVMA 2H4TA 2FYOA 2H3UA 4JN5A 2FW3A 2H3WA 1NDIA 1NM8A 2XHGA 1T7NA 2DEBA 2FY4A 2FY2A 2FY5A 1S5OA 2JGPA 4EYWA 2H3PA 2RCUA 1T7OA 4JN3A 5T3EA 1NDBA 3FOTA 1Q9JA 1T7QA 1NDFA 3FP0A 4EP9A 5DUAA 5DU9A 2VSQA 1L5AA 1Q6XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T1U A;  4EPH A;  2FY3 A;  2H4T A;  2FYO A;  2H3U A;  2FW3 A;  2H3W A;  1NDI A;  1NM8 A;  1T7N A;  2DEB A;  2FY4 A;  2FY2 A;  2FY5 A;  1S5O A;  4EYW A;  2H3P A;  2RCU A;  1T7O A;  1NDB A;  1T7Q A;  1NDF A;  4EP9 A;  1Q6X A; 
#chains in the Genus database with same CATH topology
 5FAL A;  2H4T A;  2FYO A;  4KE4 A;  1NM8 A;  2XHG A;  1NOC B;  2E1T A;  1XMD A;  2DEB A;  1EAD A;  2FY4 A;  2JGP A;  5KJU A;  4JN3 A;  1NDB A;  1Q9J A;  1C4T A;  1T7Q A;  5KJT A;  3CLA A;  4EP9 A;  5DUA A;  2VSQ A;  1Q6X A;  4CLA A;  4EPH A;  4HVM A;  3B30 A;  4JN5 A;  1NDI A;  2BGH A;  3U9B A;  1XMC A;  2IHW A;  1T7N A;  1PD5 A;  1CIA A;  2FY2 A;  3L60 A;  2RCU A;  5FAN A;  2ZBA A;  2E1V A;  2II3 A;  2RKT A;  1Q23 A;  5DU9 A;  1EAE A;  1T1U A;  5KJS A;  2FW3 A;  1XL8 A;  2II4 A;  1EAB A;  1S5O A;  1XL7 A;  2H3P A;  1T7O A;  4N72 A;  3FOT A;  1QCA A;  1NDF A;  3FP0 A;  1EAF A;  1DPC A;  1DPB A;  3B2S A;  2II5 A;  1L5A A;  2FY3 A;  1EAA A;  2CLA A;  4G2M A;  2H3U A;  4KEC A;  2H3W A;  2I9D A;  2FY5 A;  4EYW A;  1E2O A;  5T3E A;  2XR7 A;  1CLA A;  3MAE A;  4G0B A;  2E1U A;  5KJW A;  1EAC A;  1DPD A;  1SCZ A;  2RKV A;  4G22 A;  5KJV A;  3U9F A; 
#chains in the Genus database with same CATH homology
 1T1U A;  4EPH A;  2FY3 A;  4HVM A;  2H4T A;  2FYO A;  2H3U A;  4JN5 A;  2FW3 A;  2H3W A;  1NDI A;  1NM8 A;  2XHG A;  1T7N A;  2DEB A;  2FY4 A;  2FY2 A;  2FY5 A;  1S5O A;  2JGP A;  4EYW A;  2H3P A;  2RCU A;  1T7O A;  4JN3 A;  5T3E A;  1NDB A;  3FOT A;  1Q9J A;  1T7Q A;  1NDF A;  3FP0 A;  4EP9 A;  5DUA A;  5DU9 A;  2VSQ A;  1L5A A;  1Q6X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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