2XHGA

Crystal structure of the epimerization domain from the initiation module of tyrocidine biosynthesis
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
457
structure length
457
Chain Sequence
b'KSDQGIIAGNVPLTPIQKWFFGKNFTNTGHWNQSSVLYRPEGFDPKVIQSVMDKIIEHHDALRMVYQHENGNVVQHNRGLGGQLYDFFSYNLTAQPDVQQAIEAETQRLHSSMNLQEGPLVKVALFQTLHGDHLFLAIHHLVVDGISWRILFEDLATGYAQALAGQAISLPEKTDSFQSWSQWLQEYANEADLLSEIPYWESLESQAKNVSLPKDYEVTDCKQKSVRNMRIRLHPEETEQLLKHANQAYQTEINDLLLAALGLAFAEWSKLAQIVIHLEGHGREDIIEQANVARTVGWFTSQYPVLLDLKQTAPLSDYIKLTKENMRKIPRKGIGYDILKHVTLPENRGSLSFRVQPEVTFNYLGQFDADMRTELFTRSPYSGGNTLGADGKNNLSPESEVYTALNITGLIEGGELVLTFSYSSEQYREESIQQLSQSYQKHLLAIIAHCLQSHHHH'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords TYROCIDINE SYNTHETASE A
publication title Structure of the Epimerization Domain of Tyrocidine Synthetase A
pubmed doi rcsb
source organism Brevibacillus brevis
molecule tags Isomerase
total genus 161
structure length 457
sequence length 457
ec nomenclature
pdb deposition date 2010-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00668 Condensation Condensation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 2xhgA01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 2xhgA02
2RKTA 1PD5A 4N72A 1DPCA 2XHGA 3B30A 1DPBA 4HVMA 4CLAA 1EACA 2II5A 1CLAA 1XMDA 5T3EA 2XR7A 2CLAA 3U9BA 3MAEA 1XMCA 2VSQA 3FOTA 5FANA 5KJWA 5KJVA 1C4TA 4G2MA 5KJUA 1CIAA 1Q23A 2ZBAA 4G22A 1EABA 1EAEA 1EAFA 2E1UA 2E1TA 5DUAA 1NOCB 2II4A 3L60A 2BGHA 4KECA 2RKVA 1EADA 1DPDA 2II3A 3B2SA 4KE4A 3CLAA 4JN5A 3FP0A 5DU9A 1L5AA 3U9FA 5KJTA 2IHWA 2E1VA 4G0BA 5FALA 1XL8A 5KJSA 4JN3A 1E2OA 1QCAA 1XL7A 2I9DA 1SCZA 1EAAA 2JGPA 1Q9JA
chains in the Genus database with same CATH superfamily
2RKTA 4HVMA 2FW3A 2II5A 5T3EA 2XR7A 3FOTA 5FANA 1C4TA 1CIAA 2H3WA 2DEBA 2E1TA 1T1UA 5DUAA 2II4A 2RKVA 2FYOA 2H3PA 3CLAA 5DU9A 1L5AA 5KJSA 1SCZA 1EAAA 2FY5A 4EYWA 1EACA 1Q6XA 3MAEA 2VSQA 4G2MA 1Q23A 1EABA 1NDFA 1EAFA 1S5OA 2H3UA 4JN5A 3FP0A 1XL8A 1T7OA 1E2OA 4EP9A 1DPCA 2XHGA 1DPBA 4CLAA 1XMDA 2H4TA 5KJWA 2FY2A 5KJUA 4EPHA 2ZBAA 4G22A 2E1UA 1NOCB 2BGHA 2II3A 3U9FA 2FY4A 2IHWA 2FY3A 1QCAA 2JGPA 1Q9JA 1PD5A 4N72A 3B30A 1CLAA 3U9BA 2CLAA 1XMCA 5KJVA 1NDIA 1T7NA 1EAEA 1NM8A 1NDBA 1T7QA 3L60A 4KECA 1EADA 1DPDA 3B2SA 4KE4A 5KJTA 5FALA 2E1VA 4G0BA 4JN3A 1XL7A 2I9DA 2RCUA
chains in the Genus database with same CATH topology
2RKTA 4HVMA 2II5A 2FW3A 5T3EA 2XR7A 3FOTA 5FANA 1C4TA 1CIAA 2H3WA 2DEBA 1T1UA 5DUAA 2II4A 2RKVA 2FYOA 2H3PA 3CLAA 5DU9A 1L5AA 5KJSA 1SCZA 1EAAA 2FY5A 4EYWA 1EACA 1Q6XA 3MAEA 2VSQA 2RCUA 4G2MA 1Q23A 1EABA 1NDFA 1EAFA 1S5OA 2H3UA 4JN5A 3FP0A 1XL8A 1T7OA 1E2OA 4EP9A 1DPCA 2XHGA 1DPBA 4CLAA 1XMDA 2H4TA 5KJWA 2FY2A 5KJUA 4EPHA 2ZBAA 4G22A 2E1UA 1NOCB 2BGHA 2II3A 3U9FA 2FY4A 2IHWA 2FY3A 1QCAA 2JGPA 1Q9JA 1PD5A 4N72A 3B30A 1CLAA 3U9BA 2CLAA 1XMCA 5KJVA 1NDIA 1T7NA 1EAEA 1NM8A 1NDBA 1T7QA 3L60A 4KECA 1EADA 1DPDA 3B2SA 4KE4A 5KJTA 5FALA 2E1VA 4G0BA 4JN3A 1XL7A 2I9DA 2E1TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RKT A;  1PD5 A;  4N72 A;  1DPC A;  2XHG A;  3B30 A;  1DPB A;  4HVM A;  4CLA A;  1EAC A;  2II5 A;  1CLA A;  1XMD A;  5T3E A;  2XR7 A;  2CLA A;  3U9B A;  3MAE A;  1XMC A;  2VSQ A;  3FOT A;  5FAN A;  5KJW A;  5KJV A;  1C4T A;  4G2M A;  5KJU A;  1CIA A;  1Q23 A;  2ZBA A;  4G22 A;  1EAB A;  1EAE A;  1EAF A;  2E1U A;  2E1T A;  5DUA A;  1NOC B;  2II4 A;  3L60 A;  2BGH A;  4KEC A;  2RKV A;  1EAD A;  1DPD A;  2II3 A;  3B2S A;  4KE4 A;  3CLA A;  4JN5 A;  3FP0 A;  5DU9 A;  1L5A A;  3U9F A;  5KJT A;  2IHW A;  2E1V A;  4G0B A;  5FAL A;  1XL8 A;  5KJS A;  4JN3 A;  1E2O A;  1QCA A;  1XL7 A;  2I9D A;  1SCZ A;  1EAA A;  2JGP A;  1Q9J A; 
#chains in the Genus database with same CATH topology
 2RKT A;  4HVM A;  2FW3 A;  2II5 A;  5T3E A;  2XR7 A;  3FOT A;  5FAN A;  1C4T A;  1CIA A;  2H3W A;  2DEB A;  2E1T A;  1T1U A;  5DUA A;  2II4 A;  2RKV A;  2FYO A;  2H3P A;  3CLA A;  5DU9 A;  1L5A A;  5KJS A;  1SCZ A;  1EAA A;  2FY5 A;  4EYW A;  1EAC A;  1Q6X A;  3MAE A;  2VSQ A;  4G2M A;  1Q23 A;  1EAB A;  1NDF A;  1EAF A;  1S5O A;  2H3U A;  4JN5 A;  3FP0 A;  1XL8 A;  1T7O A;  1E2O A;  4EP9 A;  1DPC A;  2XHG A;  1DPB A;  4CLA A;  1XMD A;  2H4T A;  5KJW A;  2FY2 A;  5KJU A;  4EPH A;  2ZBA A;  4G22 A;  2E1U A;  1NOC B;  2BGH A;  2II3 A;  3U9F A;  2FY4 A;  2IHW A;  2FY3 A;  1QCA A;  2JGP A;  1Q9J A;  1PD5 A;  4N72 A;  3B30 A;  1CLA A;  3U9B A;  2CLA A;  1XMC A;  5KJV A;  1NDI A;  1T7N A;  1EAE A;  1NM8 A;  1NDB A;  1T7Q A;  3L60 A;  4KEC A;  1EAD A;  1DPD A;  3B2S A;  4KE4 A;  5KJT A;  5FAL A;  2E1V A;  4G0B A;  4JN3 A;  1XL7 A;  2I9D A;  2RCU A; 
#chains in the Genus database with same CATH homology
 2RKT A;  4HVM A;  2II5 A;  2FW3 A;  5T3E A;  2XR7 A;  3FOT A;  5FAN A;  1C4T A;  1CIA A;  2H3W A;  2DEB A;  1T1U A;  5DUA A;  2II4 A;  2RKV A;  2FYO A;  2H3P A;  3CLA A;  5DU9 A;  1L5A A;  5KJS A;  1SCZ A;  1EAA A;  2FY5 A;  4EYW A;  1EAC A;  1Q6X A;  3MAE A;  2VSQ A;  2RCU A;  4G2M A;  1Q23 A;  1EAB A;  1NDF A;  1EAF A;  1S5O A;  2H3U A;  4JN5 A;  3FP0 A;  1XL8 A;  1T7O A;  1E2O A;  4EP9 A;  1DPC A;  2XHG A;  1DPB A;  4CLA A;  1XMD A;  2H4T A;  5KJW A;  2FY2 A;  5KJU A;  4EPH A;  2ZBA A;  4G22 A;  2E1U A;  1NOC B;  2BGH A;  2II3 A;  3U9F A;  2FY4 A;  2IHW A;  2FY3 A;  1QCA A;  2JGP A;  1Q9J A;  1PD5 A;  4N72 A;  3B30 A;  1CLA A;  3U9B A;  2CLA A;  1XMC A;  5KJV A;  1NDI A;  1T7N A;  1EAE A;  1NM8 A;  1NDB A;  1T7Q A;  3L60 A;  4KEC A;  1EAD A;  1DPD A;  3B2S A;  4KE4 A;  5KJT A;  5FAL A;  2E1V A;  4G0B A;  4JN3 A;  1XL7 A;  2I9D A;  2E1T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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