2XHGA

Crystal structure of the epimerization domain from the initiation module of tyrocidine biosynthesis
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
sequence length
457
structure length
457
Chain Sequence
KSDQGIIAGNVPLTPIQKWFFGKNFTNTGHWNQSSVLYRPEGFDPKVIQSVMDKIIEHHDALRMVYQHENGNVVQHNRGLGGQLYDFFSYNLTAQPDVQQAIEAETQRLHSSMNLQEGPLVKVALFQTLHGDHLFLAIHHLVVDGISWRILFEDLATGYAQALAGQAISLPEKTDSFQSWSQWLQEYANEADLLSEIPYWESLESQAKNVSLPKDYEVTDCKQKSVRNMRIRLHPEETEQLLKHANQAYQTEINDLLLAALGLAFAEWSKLAQIVIHLEGHGREDIIEQANVARTVGWFTSQYPVLLDLKQTAPLSDYIKLTKENMRKIPRKGIGYDILKHVTLPENRGSLSFRVQPEVTFNYLGQFDADMRTELFTRSPYSGGNTLGADGKNNLSPESEVYTALNITGLIEGGELVLTFSYSSEQYREESIQQLSQSYQKHLLAIIAHCLQSHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords TYROCIDINE SYNTHETASE A
publication title Structure of the Epimerization Domain of Tyrocidine Synthetase A
pubmed doi rcsb
source organism Brevibacillus brevis
total genus 161
structure length 457
sequence length 457
ec nomenclature
pdb deposition date 2010-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00668 Condensation Condensation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 2xhgA01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 2xhgA02
1CIAA 2CLAA 4KE4A 2IHWA 3FOTA 1XMCA 5DUAA 1Q23A 2E1UA 2XR7A 1PD5A 1XL8A 5DU9A 5FALA 1XMDA 1L5AA 2JGPA 1EADA 1SCZA 2VSQA 4JN3A 4N72A 2ZBAA 5T3EA 3U9FA 4KECA 3CLAA 4CLAA 1DPCA 1EAFA 1EACA 2BGHA 2II3A 4G2MA 1EAAA 2RKVA 5KJTA 5KJUA 2XHGA 3L60A 4HVMA 1EABA 5KJVA 2E1TA 2II4A 1EAEA 1DPBA 1E2OA 3U9BA 5FANA 5KJWA 1DPDA 4G0BA 4G22A 1NOCB 1XL7A 2E1VA 3FP0A 1CLAA 1Q9JA 3MAEA 5KJSA 2II5A 4JN5A 2RKTA 1QCAA 3B30A 3B2SA 1C4TA 2I9DA
chains in the Genus database with same CATH superfamily
4EPHA 2FY3A 3FOTA 1T7NA 1XMCA 1L5AA 2DEBA 1T7QA 1NDIA 2ZBAA 1DPCA 2BGHA 2II3A 1EAAA 1DPBA 1E2OA 4G0BA 1CLAA 3MAEA 4EYWA 3B2SA 1C4TA 4CLAA 4KE4A 1Q23A 5FALA 1SCZA 5T3EA 4KECA 2FY4A 1EAFA 4G2MA 1NDFA 1EABA 2E1TA 2II4A 1EAEA 1DPDA 4G22A 2E1VA 1XL7A 1Q9JA 1NM8A 4EP9A 1QCAA 2FYOA 3B30A 2CLAA 2FY5A 5DU9A 1XL8A 2FY2A 4JN3A 3U9FA 2H3PA 2FW3A 3L60A 5FANA 5KJSA 1S5OA 2II5A 5DUAA 1CIAA 2H3WA 2IHWA 2H3UA 1T1UA 2E1UA 2XR7A 1PD5A 1Q6XA 1XMDA 2JGPA 1EADA 2VSQA 4N72A 1T7OA 3CLAA 1EACA 2RKVA 5KJTA 5KJUA 2XHGA 4HVMA 5KJVA 2RCUA 3U9BA 5KJWA 3FP0A 1NOCB 2H4TA 4JN5A 2RKTA 1NDBA 2I9DA
chains in the Genus database with same CATH topology
4EPHA 2FY3A 3FOTA 1XMCA 1T7NA 1L5AA 2DEBA 1T7QA 1NDIA 2ZBAA 1DPCA 2BGHA 2II3A 1EAAA 1DPBA 1E2OA 4G0BA 1CLAA 3MAEA 4EYWA 3B2SA 4CLAA 1C4TA 4KE4A 1Q23A 5FALA 1SCZA 5T3EA 4KECA 2FY4A 1EAFA 4G2MA 1NDFA 1EABA 2E1TA 2II4A 1EAEA 1DPDA 4G22A 2E1VA 1XL7A 1Q9JA 1NM8A 4EP9A 1QCAA 2FYOA 3B30A 2CLAA 2FY5A 5DU9A 1XL8A 3U9FA 4JN3A 2FY2A 2H3PA 2FW3A 3L60A 5FANA 5KJSA 1S5OA 2II5A 5DUAA 1CIAA 2H3WA 2IHWA 2H3UA 1T1UA 2E1UA 2XR7A 1PD5A 1Q6XA 1XMDA 2JGPA 1EADA 2VSQA 4N72A 1T7OA 3CLAA 1EACA 2RKVA 5KJTA 5KJUA 2XHGA 4HVMA 5KJVA 2RCUA 3U9BA 5KJWA 1NOCB 3FP0A 2H4TA 4JN5A 2RKTA 1NDBA 2I9DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CIA A;  2CLA A;  4KE4 A;  2IHW A;  3FOT A;  1XMC A;  5DUA A;  1Q23 A;  2E1U A;  2XR7 A;  1PD5 A;  1XL8 A;  5DU9 A;  5FAL A;  1XMD A;  1L5A A;  2JGP A;  1EAD A;  1SCZ A;  2VSQ A;  4JN3 A;  4N72 A;  2ZBA A;  5T3E A;  3U9F A;  4KEC A;  3CLA A;  4CLA A;  1DPC A;  1EAF A;  1EAC A;  2BGH A;  2II3 A;  4G2M A;  1EAA A;  2RKV A;  5KJT A;  5KJU A;  2XHG A;  3L60 A;  4HVM A;  1EAB A;  5KJV A;  2E1T A;  2II4 A;  1EAE A;  1DPB A;  1E2O A;  3U9B A;  5FAN A;  5KJW A;  1DPD A;  4G0B A;  4G22 A;  1NOC B;  1XL7 A;  2E1V A;  3FP0 A;  1CLA A;  1Q9J A;  3MAE A;  5KJS A;  2II5 A;  4JN5 A;  2RKT A;  1QCA A;  3B30 A;  3B2S A;  1C4T A;  2I9D A; 
#chains in the Genus database with same CATH topology
 4EPH A;  2FY3 A;  3FOT A;  1T7N A;  1XMC A;  1L5A A;  2DEB A;  1T7Q A;  1NDI A;  2ZBA A;  1DPC A;  2BGH A;  2II3 A;  1EAA A;  1DPB A;  1E2O A;  4G0B A;  1CLA A;  3MAE A;  4EYW A;  3B2S A;  1C4T A;  4CLA A;  4KE4 A;  1Q23 A;  5FAL A;  1SCZ A;  5T3E A;  4KEC A;  2FY4 A;  1EAF A;  4G2M A;  1NDF A;  1EAB A;  2E1T A;  2II4 A;  1EAE A;  1DPD A;  4G22 A;  2E1V A;  1XL7 A;  1Q9J A;  1NM8 A;  4EP9 A;  1QCA A;  2FYO A;  3B30 A;  2CLA A;  2FY5 A;  5DU9 A;  1XL8 A;  2FY2 A;  4JN3 A;  3U9F A;  2H3P A;  2FW3 A;  3L60 A;  5FAN A;  5KJS A;  1S5O A;  2II5 A;  5DUA A;  1CIA A;  2H3W A;  2IHW A;  2H3U A;  1T1U A;  2E1U A;  2XR7 A;  1PD5 A;  1Q6X A;  1XMD A;  2JGP A;  1EAD A;  2VSQ A;  4N72 A;  1T7O A;  3CLA A;  1EAC A;  2RKV A;  5KJT A;  5KJU A;  2XHG A;  4HVM A;  5KJV A;  2RCU A;  3U9B A;  5KJW A;  3FP0 A;  1NOC B;  2H4T A;  4JN5 A;  2RKT A;  1NDB A;  2I9D A; 
#chains in the Genus database with same CATH homology
 4EPH A;  2FY3 A;  3FOT A;  1XMC A;  1T7N A;  1L5A A;  2DEB A;  1T7Q A;  1NDI A;  2ZBA A;  1DPC A;  2BGH A;  2II3 A;  1EAA A;  1DPB A;  1E2O A;  4G0B A;  1CLA A;  3MAE A;  4EYW A;  3B2S A;  4CLA A;  1C4T A;  4KE4 A;  1Q23 A;  5FAL A;  1SCZ A;  5T3E A;  4KEC A;  2FY4 A;  1EAF A;  4G2M A;  1NDF A;  1EAB A;  2E1T A;  2II4 A;  1EAE A;  1DPD A;  4G22 A;  2E1V A;  1XL7 A;  1Q9J A;  1NM8 A;  4EP9 A;  1QCA A;  2FYO A;  3B30 A;  2CLA A;  2FY5 A;  5DU9 A;  1XL8 A;  3U9F A;  4JN3 A;  2FY2 A;  2H3P A;  2FW3 A;  3L60 A;  5FAN A;  5KJS A;  1S5O A;  2II5 A;  5DUA A;  1CIA A;  2H3W A;  2IHW A;  2H3U A;  1T1U A;  2E1U A;  2XR7 A;  1PD5 A;  1Q6X A;  1XMD A;  2JGP A;  1EAD A;  2VSQ A;  4N72 A;  1T7O A;  3CLA A;  1EAC A;  2RKV A;  5KJT A;  5KJU A;  2XHG A;  4HVM A;  5KJV A;  2RCU A;  3U9B A;  5KJW A;  1NOC B;  3FP0 A;  2H4T A;  4JN5 A;  2RKT A;  1NDB A;  2I9D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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