3L60A

Crystal structure of branched-chain alpha-keto acid dehydrogenase subunit e2 from mycobacterium tuberculosis
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
229
structure length
229
Chain Sequence
PDVRPVHGVHARMAEKMTLSHKEIPTAKASVEVICAELLRLRDRFVSAAPEITPFALTLRLLVIALKHNVILNSTWVDSGEGPQVHVHRGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTCVFDHRVVDGAQVAQFMCELRDLIESPETALLDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE
publication title Crystal Structure of Branched-Chain Alpha-Keto Acid Dehydrogenase Subunit E2 from Mycobacterium Tuberculosis
rcsb
source organism Mycobacterium tuberculosis
total genus 69
structure length 229
sequence length 229
ec nomenclature ec 2.3.1.168: Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
pdb deposition date 2009-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 3l60A01
5KJTA 1SCZA 3MAEA 1XMCA 1EAFA 1PD5A 1Q9JA 2VSQA 3U9FA 4KE4A 1L5AA 1DPCA 2RKTA 1XL7A 4N72A 5KJWA 2E1TA 5DUAA 5T3EA 1DPDA 2II5A 1CIAA 4CLAA 1EAAA 4G22A 1QCAA 2II3A 3B2SA 4G2MA 5KJSA 5FANA 1EADA 2E1UA 2RKVA 2XR7A 2JGPA 1XMDA 1EAEA 1EACA 4HVMA 2IHWA 2ZBAA 2I9DA 1EABA 1Q23A 2CLAA 4JN3A 2E1VA 4G0BA 1DPBA 2BGHA 2II4A 1NOCB 3U9BA 3FOTA 1XL8A 3L60A 1CLAA 2XHGA 3FP0A 3B30A 4JN5A 5KJVA 1C4TA 5FALA 3CLAA 4KECA 5DU9A 5KJUA 1E2OA
chains in the Genus database with same CATH superfamily
2RCUA 1L5AA 4N72A 1DPDA 1CIAA 4CLAA 4G22A 5KJSA 2II3A 4G2MA 1EAEA 4HVMA 2I9DA 4G0BA 2FY4A 1CLAA 2H3UA 1NDIA 1T1UA 4JN5A 5FALA 2FY5A 1T7QA 3MAEA 1T7NA 1Q9JA 4KE4A 2II5A 4EYWA 2FW3A 2IHWA 2ZBAA 1EABA 2CLAA 1DPBA 3L60A 5KJVA 3CLAA 5KJUA 1E2OA 5KJTA 2FY2A 1XMCA 1PD5A 3U9FA 2RKTA 1XL7A 1S5OA 2E1TA 2DEBA 4EP9A 3B2SA 2E1UA 2JGPA 1XMDA 4EPHA 4JN3A 2H3WA 2BGHA 2II4A 3U9BA 1XL8A 1Q6XA 2XHGA 3B30A 1C4TA 4KECA 5DU9A 2H4TA 1SCZA 2FYOA 1NM8A 1EAFA 2VSQA 1DPCA 1NDBA 2H3PA 5KJWA 5DUAA 5T3EA 1EAAA 1QCAA 5FANA 1EADA 1NDFA 2RKVA 2XR7A 1EACA 1T7OA 1Q23A 2E1VA 1NOCB 3FOTA 3FP0A 2FY3A
chains in the Genus database with same CATH topology
5KJTA 1SCZA 3MAEA 1XMCA 1EAFA 1PD5A 1Q9JA 2VSQA 3U9FA 4KE4A 1L5AA 1DPCA 2RKTA 1XL7A 4N72A 5KJWA 2E1TA 5DUAA 5T3EA 1DPDA 2II5A 1CIAA 4CLAA 1EAAA 4G22A 1QCAA 2II3A 3B2SA 4G2MA 5KJSA 5FANA 1EADA 2E1UA 2RKVA 2XR7A 2JGPA 1XMDA 1EAEA 1EACA 4HVMA 2IHWA 2ZBAA 2I9DA 1EABA 1Q23A 2CLAA 4JN3A 2E1VA 4G0BA 1DPBA 2BGHA 2II4A 1NOCB 3U9BA 3FOTA 1XL8A 3L60A 1CLAA 2XHGA 3FP0A 3B30A 4JN5A 5KJVA 1C4TA 5FALA 3CLAA 4KECA 5DU9A 5KJUA 1E2OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KJT A;  1SCZ A;  3MAE A;  1XMC A;  1EAF A;  1PD5 A;  1Q9J A;  2VSQ A;  3U9F A;  4KE4 A;  1L5A A;  1DPC A;  2RKT A;  1XL7 A;  4N72 A;  5KJW A;  2E1T A;  5DUA A;  5T3E A;  1DPD A;  2II5 A;  1CIA A;  4CLA A;  1EAA A;  4G22 A;  1QCA A;  2II3 A;  3B2S A;  4G2M A;  5KJS A;  5FAN A;  1EAD A;  2E1U A;  2RKV A;  2XR7 A;  2JGP A;  1XMD A;  1EAE A;  1EAC A;  4HVM A;  2IHW A;  2ZBA A;  2I9D A;  1EAB A;  1Q23 A;  2CLA A;  4JN3 A;  2E1V A;  4G0B A;  1DPB A;  2BGH A;  2II4 A;  1NOC B;  3U9B A;  3FOT A;  1XL8 A;  3L60 A;  1CLA A;  2XHG A;  3FP0 A;  3B30 A;  4JN5 A;  5KJV A;  1C4T A;  5FAL A;  3CLA A;  4KEC A;  5DU9 A;  5KJU A;  1E2O A; 
#chains in the Genus database with same CATH topology
 2RCU A;  1L5A A;  4N72 A;  1DPD A;  1CIA A;  4CLA A;  4G22 A;  5KJS A;  2II3 A;  4G2M A;  1EAE A;  4HVM A;  2I9D A;  4G0B A;  2FY4 A;  1CLA A;  2H3U A;  1NDI A;  1T1U A;  4JN5 A;  5FAL A;  2FY5 A;  1T7Q A;  3MAE A;  1T7N A;  1Q9J A;  4KE4 A;  2II5 A;  4EYW A;  2FW3 A;  2IHW A;  2ZBA A;  1EAB A;  2CLA A;  1DPB A;  3L60 A;  5KJV A;  3CLA A;  5KJU A;  1E2O A;  5KJT A;  2FY2 A;  1XMC A;  1PD5 A;  3U9F A;  2RKT A;  1XL7 A;  1S5O A;  2E1T A;  2DEB A;  4EP9 A;  3B2S A;  2E1U A;  2JGP A;  1XMD A;  4EPH A;  4JN3 A;  2H3W A;  2BGH A;  2II4 A;  3U9B A;  1XL8 A;  1Q6X A;  2XHG A;  3B30 A;  1C4T A;  4KEC A;  5DU9 A;  2H4T A;  1SCZ A;  2FYO A;  1NM8 A;  1EAF A;  2VSQ A;  1DPC A;  1NDB A;  2H3P A;  5KJW A;  5DUA A;  5T3E A;  1EAA A;  1QCA A;  5FAN A;  1EAD A;  1NDF A;  2RKV A;  2XR7 A;  1EAC A;  1T7O A;  1Q23 A;  2E1V A;  1NOC B;  3FOT A;  3FP0 A;  2FY3 A; 
#chains in the Genus database with same CATH homology
 5KJT A;  1SCZ A;  3MAE A;  1XMC A;  1EAF A;  1PD5 A;  1Q9J A;  2VSQ A;  3U9F A;  4KE4 A;  1L5A A;  1DPC A;  2RKT A;  1XL7 A;  4N72 A;  5KJW A;  2E1T A;  5DUA A;  5T3E A;  1DPD A;  2II5 A;  1CIA A;  4CLA A;  1EAA A;  4G22 A;  1QCA A;  2II3 A;  3B2S A;  4G2M A;  5KJS A;  5FAN A;  1EAD A;  2E1U A;  2RKV A;  2XR7 A;  2JGP A;  1XMD A;  1EAE A;  1EAC A;  4HVM A;  2IHW A;  2ZBA A;  2I9D A;  1EAB A;  1Q23 A;  2CLA A;  4JN3 A;  2E1V A;  4G0B A;  1DPB A;  2BGH A;  2II4 A;  1NOC B;  3U9B A;  3FOT A;  1XL8 A;  3L60 A;  1CLA A;  2XHG A;  3FP0 A;  3B30 A;  4JN5 A;  5KJV A;  1C4T A;  5FAL A;  3CLA A;  4KEC A;  5DU9 A;  5KJU A;  1E2O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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