3L60A

Crystal structure of branched-chain alpha-keto acid dehydrogenase subunit e2 from mycobacterium tuberculosis
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
229
structure length
229
Chain Sequence
PDVRPVHGVHARMAEKMTLSHKEIPTAKASVEVICAELLRLRDRFVSAAPEITPFALTLRLLVIALKHNVILNSTWVDSGEGPQVHVHRGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTCVFDHRVVDGAQVAQFMCELRDLIESPETALLDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE
publication title Crystal Structure of Branched-Chain Alpha-Keto Acid Dehydrogenase Subunit E2 from Mycobacterium Tuberculosis
rcsb
source organism Mycobacterium tuberculosis
molecule tags Oxidoreductase
total genus 69
structure length 229
sequence length 229
ec nomenclature ec 2.3.1.168: Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
pdb deposition date 2009-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 3l60A01
4N72A 1EADA 2E1TA 4JN3A 3B30A 1CIAA 4G2MA 2E1UA 2CLAA 3L60A 4G0BA 1XMDA 2RKTA 4KECA 3B2SA 5KJTA 2I9DA 1EABA 2E1VA 3MAEA 5KJUA 1CLAA 1EAAA 1EAFA 1EAEA 1NOCB 5DU9A 5FANA 5T3EA 5KJVA 1E2OA 1EACA 2VSQA 4KE4A 2II3A 3U9FA 2XHGA 1XMCA 5KJSA 1XL8A 1DPCA 1QCAA 1DPDA 2JGPA 2RKVA 5KJWA 3CLAA 3FOTA 1Q9JA 5DUAA 5FALA 4G22A 1SCZA 2ZBAA 2II4A 4HVMA 4CLAA 2BGHA 2II5A 3FP0A 1DPBA 3U9BA 1PD5A 1XL7A 2IHWA 4JN5A 1C4TA 1L5AA 1Q23A 2XR7A
chains in the Genus database with same CATH superfamily
3B30A 4G0BA 2RKTA 4KECA 2I9DA 1CLAA 5DU9A 5T3EA 2VSQA 4EP9A 2II3A 5KJSA 2RKVA 1S5OA 3CLAA 3FOTA 4EPHA 1NDBA 2RCUA 2II5A 3FP0A 1T1UA 3U9BA 1Q23A 1T7QA 4JN3A 1CIAA 3B2SA 4EYWA 2E1VA 2FW3A 2H4TA 5KJUA 1EAFA 5KJVA 4KE4A 2FY5A 1Q6XA 2JGPA 4G22A 1SCZA 2ZBAA 1DPBA 2IHWA 1XL7A 4JN5A 1L5AA 4N72A 2FYOA 2FY4A 2E1UA 2CLAA 2H3PA 5KJTA 1EABA 3MAEA 5FANA 2XHGA 1NDFA 1XL8A 1DPCA 5KJWA 1DPDA 5FALA 2DEBA 2FY2A 1PD5A 2XR7A 1EADA 2E1TA 1NDIA 4G2MA 2H3WA 3L60A 1XMDA 1T7NA 1NM8A 1EAAA 1EAEA 1NOCB 1E2OA 1EACA 3U9FA 1XMCA 2H3UA 1QCAA 5DUAA 1Q9JA 1T7OA 4HVMA 2II4A 2FY3A 2BGHA 1C4TA 4CLAA
chains in the Genus database with same CATH topology
4N72A 1EADA 2E1TA 4JN3A 3B30A 1CIAA 4G2MA 2E1UA 2CLAA 3L60A 4G0BA 1XMDA 2RKTA 4KECA 3B2SA 5KJTA 2I9DA 1EABA 2E1VA 3MAEA 5KJUA 1CLAA 1EAAA 1EAFA 1EAEA 1NOCB 5DU9A 5FANA 5T3EA 5KJVA 1E2OA 1EACA 2VSQA 4KE4A 2II3A 3U9FA 2XHGA 1XMCA 5KJSA 1XL8A 1DPCA 1QCAA 1DPDA 2JGPA 2RKVA 5KJWA 3CLAA 3FOTA 1Q9JA 5DUAA 5FALA 4G22A 1SCZA 2ZBAA 2II4A 4HVMA 4CLAA 2BGHA 2II5A 3FP0A 1DPBA 3U9BA 1PD5A 1XL7A 2IHWA 4JN5A 1C4TA 1L5AA 1Q23A 2XR7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N72 A;  1EAD A;  2E1T A;  4JN3 A;  3B30 A;  1CIA A;  4G2M A;  2E1U A;  2CLA A;  3L60 A;  4G0B A;  1XMD A;  2RKT A;  4KEC A;  3B2S A;  5KJT A;  2I9D A;  1EAB A;  2E1V A;  3MAE A;  5KJU A;  1CLA A;  1EAA A;  1EAF A;  1EAE A;  1NOC B;  5DU9 A;  5FAN A;  5T3E A;  5KJV A;  1E2O A;  1EAC A;  2VSQ A;  4KE4 A;  2II3 A;  3U9F A;  2XHG A;  1XMC A;  5KJS A;  1XL8 A;  1DPC A;  1QCA A;  1DPD A;  2JGP A;  2RKV A;  5KJW A;  3CLA A;  3FOT A;  1Q9J A;  5DUA A;  5FAL A;  4G22 A;  1SCZ A;  2ZBA A;  2II4 A;  4HVM A;  4CLA A;  2BGH A;  2II5 A;  3FP0 A;  1DPB A;  3U9B A;  1PD5 A;  1XL7 A;  2IHW A;  4JN5 A;  1C4T A;  1L5A A;  1Q23 A;  2XR7 A; 
#chains in the Genus database with same CATH topology
 3B30 A;  4G0B A;  2RKT A;  4KEC A;  2I9D A;  1CLA A;  5DU9 A;  5T3E A;  2VSQ A;  4EP9 A;  2II3 A;  5KJS A;  2RKV A;  1S5O A;  3CLA A;  3FOT A;  4EPH A;  1NDB A;  2RCU A;  2II5 A;  3FP0 A;  1T1U A;  3U9B A;  1Q23 A;  1T7Q A;  4JN3 A;  1CIA A;  3B2S A;  4EYW A;  2E1V A;  2FW3 A;  2H4T A;  5KJU A;  1EAF A;  5KJV A;  4KE4 A;  2FY5 A;  1Q6X A;  2JGP A;  4G22 A;  1SCZ A;  2ZBA A;  1DPB A;  2IHW A;  1XL7 A;  4JN5 A;  1L5A A;  4N72 A;  2FYO A;  2FY4 A;  2E1U A;  2CLA A;  2H3P A;  5KJT A;  1EAB A;  3MAE A;  5FAN A;  2XHG A;  1NDF A;  1XL8 A;  1DPC A;  5KJW A;  1DPD A;  5FAL A;  2DEB A;  2FY2 A;  1PD5 A;  2XR7 A;  1EAD A;  2E1T A;  1NDI A;  4G2M A;  2H3W A;  3L60 A;  1XMD A;  1T7N A;  1NM8 A;  1EAA A;  1EAE A;  1NOC B;  1E2O A;  1EAC A;  3U9F A;  1XMC A;  2H3U A;  1QCA A;  5DUA A;  1Q9J A;  1T7O A;  4HVM A;  2II4 A;  2FY3 A;  2BGH A;  1C4T A;  4CLA A; 
#chains in the Genus database with same CATH homology
 4N72 A;  1EAD A;  2E1T A;  4JN3 A;  3B30 A;  1CIA A;  4G2M A;  2E1U A;  2CLA A;  3L60 A;  4G0B A;  1XMD A;  2RKT A;  4KEC A;  3B2S A;  5KJT A;  2I9D A;  1EAB A;  2E1V A;  3MAE A;  5KJU A;  1CLA A;  1EAA A;  1EAF A;  1EAE A;  1NOC B;  5DU9 A;  5FAN A;  5T3E A;  5KJV A;  1E2O A;  1EAC A;  2VSQ A;  4KE4 A;  2II3 A;  3U9F A;  2XHG A;  1XMC A;  5KJS A;  1XL8 A;  1DPC A;  1QCA A;  1DPD A;  2JGP A;  2RKV A;  5KJW A;  3CLA A;  3FOT A;  1Q9J A;  5DUA A;  5FAL A;  4G22 A;  1SCZ A;  2ZBA A;  2II4 A;  4HVM A;  4CLA A;  2BGH A;  2II5 A;  3FP0 A;  1DPB A;  3U9B A;  1PD5 A;  1XL7 A;  2IHW A;  4JN5 A;  1C4T A;  1L5A A;  1Q23 A;  2XR7 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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