3L60A

Crystal structure of branched-chain alpha-keto acid dehydrogenase subunit e2 from mycobacterium tuberculosis
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
229
structure length
229
Chain Sequence
PDVRPVHGVHARMAEKMTLSHKEIPTAKASVEVICAELLRLRDRFVSAAPEITPFALTLRLLVIALKHNVILNSTWVDSGEGPQVHVHRGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVVARPTMTLTCVFDHRVVDGAQVAQFMCELRDLIESPETALLDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE
publication title Crystal Structure of Branched-Chain Alpha-Keto Acid Dehydrogenase Subunit E2 from Mycobacterium Tuberculosis
rcsb
source organism Mycobacterium tuberculosis
molecule tags Oxidoreductase
total genus 69
structure length 229
sequence length 229
ec nomenclature ec 2.3.1.168: Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase.
pdb deposition date 2009-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 3l60A01
1EAAA 1CLAA 3MAEA 4KECA 1E2OA 3FOTA 5KJWA 4HVMA 4CLAA 2II5A 1DPBA 2CLAA 3CLAA 1Q23A 1EABA 1EAEA 1XMCA 3B30A 2RKTA 1XL7A 1DPCA 5KJTA 2E1TA 2E1VA 2JGPA 3U9FA 2IHWA 2II3A 3U9BA 1DPDA 1XMDA 2BGHA 4N72A 5KJSA 4JN3A 3FP0A 5DU9A 1NOCB 2E1UA 4G0BA 5FANA 1XL8A 1EADA 1CIAA 5FALA 1PD5A 1SCZA 4G2MA 2II4A 2RKVA 1EAFA 1C4TA 3L60A 2VSQA 4KE4A 1EACA 1Q9JA 2I9DA 4G22A 5DUAA 5T3EA 1L5AA 2XR7A 4JN5A 1QCAA 2XHGA 2ZBAA 3B2SA 5KJUA 5KJVA
chains in the Genus database with same CATH superfamily
1CLAA 4EP9A 4HVMA 4EYWA 3CLAA 1T7NA 2FY5A 2RKTA 1XL7A 1DPCA 4EPHA 2H3UA 2II3A 1NDIA 2FW3A 2FY2A 1NDFA 2E1UA 2H3PA 5FALA 1S5OA 4G2MA 2II4A 2RKVA 3L60A 2VSQA 1NM8A 3B2SA 5KJUA 5KJVA 2H4TA 1T7QA 1E2OA 4CLAA 1Q23A 1EABA 1EAEA 2DEBA 2E1TA 3U9FA 2IHWA 2FYOA 1Q6XA 1XMDA 2H3WA 1XL8A 1CIAA 4G22A 5DUAA 2XR7A 1EAAA 4KECA 1NDBA 5KJWA 2CLAA 1XMCA 2E1VA 2JGPA 3U9BA 1DPDA 2BGHA 5KJSA 4G0BA 4KE4A 1EAFA 1EACA 2I9DA 4JN5A 1T1UA 1T7OA 3MAEA 3FOTA 2FY4A 2II5A 1DPBA 3B30A 5KJTA 4N72A 4JN3A 3FP0A 1NOCB 5FANA 1EADA 1PD5A 1SCZA 5DU9A 2RCUA 1C4TA 1Q9JA 5T3EA 2FY3A 1L5AA 1QCAA 2XHGA 2ZBAA
chains in the Genus database with same CATH topology
1EAAA 1CLAA 3MAEA 4KECA 1E2OA 3FOTA 5KJWA 4HVMA 4CLAA 2II5A 1DPBA 2CLAA 3CLAA 1Q23A 1EABA 1EAEA 1XMCA 3B30A 2RKTA 1XL7A 1DPCA 5KJTA 2E1TA 2E1VA 2JGPA 3U9FA 2IHWA 2II3A 3U9BA 1DPDA 1XMDA 2BGHA 4N72A 5KJSA 4JN3A 3FP0A 5DU9A 1NOCB 2E1UA 4G0BA 5FANA 1XL8A 1EADA 1CIAA 5FALA 1PD5A 1SCZA 4G2MA 2II4A 2RKVA 1EAFA 1C4TA 3L60A 2VSQA 4KE4A 1EACA 1Q9JA 2I9DA 4G22A 5DUAA 5T3EA 1L5AA 2XR7A 4JN5A 1QCAA 2XHGA 2ZBAA 3B2SA 5KJUA 5KJVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EAA A;  1CLA A;  3MAE A;  4KEC A;  1E2O A;  3FOT A;  5KJW A;  4HVM A;  4CLA A;  2II5 A;  1DPB A;  2CLA A;  3CLA A;  1Q23 A;  1EAB A;  1EAE A;  1XMC A;  3B30 A;  2RKT A;  1XL7 A;  1DPC A;  5KJT A;  2E1T A;  2E1V A;  2JGP A;  3U9F A;  2IHW A;  2II3 A;  3U9B A;  1DPD A;  1XMD A;  2BGH A;  4N72 A;  5KJS A;  4JN3 A;  3FP0 A;  5DU9 A;  1NOC B;  2E1U A;  4G0B A;  5FAN A;  1XL8 A;  1EAD A;  1CIA A;  5FAL A;  1PD5 A;  1SCZ A;  4G2M A;  2II4 A;  2RKV A;  1EAF A;  1C4T A;  3L60 A;  2VSQ A;  4KE4 A;  1EAC A;  1Q9J A;  2I9D A;  4G22 A;  5DUA A;  5T3E A;  1L5A A;  2XR7 A;  4JN5 A;  1QCA A;  2XHG A;  2ZBA A;  3B2S A;  5KJU A;  5KJV A; 
#chains in the Genus database with same CATH topology
 1CLA A;  4EP9 A;  4HVM A;  4EYW A;  3CLA A;  1T7N A;  2FY5 A;  2RKT A;  1XL7 A;  1DPC A;  4EPH A;  2H3U A;  2II3 A;  1NDI A;  2FW3 A;  2FY2 A;  1NDF A;  2E1U A;  2H3P A;  5FAL A;  1S5O A;  4G2M A;  2II4 A;  2RKV A;  3L60 A;  2VSQ A;  1NM8 A;  3B2S A;  5KJU A;  5KJV A;  2H4T A;  1T7Q A;  1E2O A;  4CLA A;  1Q23 A;  1EAB A;  1EAE A;  2DEB A;  2E1T A;  3U9F A;  2IHW A;  2FYO A;  1Q6X A;  1XMD A;  2H3W A;  1XL8 A;  1CIA A;  4G22 A;  5DUA A;  2XR7 A;  1EAA A;  4KEC A;  1NDB A;  5KJW A;  2CLA A;  1XMC A;  2E1V A;  2JGP A;  3U9B A;  1DPD A;  2BGH A;  5KJS A;  4G0B A;  4KE4 A;  1EAF A;  1EAC A;  2I9D A;  4JN5 A;  1T1U A;  1T7O A;  3MAE A;  3FOT A;  2FY4 A;  2II5 A;  1DPB A;  3B30 A;  5KJT A;  4N72 A;  4JN3 A;  3FP0 A;  1NOC B;  5FAN A;  1EAD A;  1PD5 A;  1SCZ A;  5DU9 A;  2RCU A;  1C4T A;  1Q9J A;  5T3E A;  2FY3 A;  1L5A A;  1QCA A;  2XHG A;  2ZBA A; 
#chains in the Genus database with same CATH homology
 1EAA A;  1CLA A;  3MAE A;  4KEC A;  1E2O A;  3FOT A;  5KJW A;  4HVM A;  4CLA A;  2II5 A;  1DPB A;  2CLA A;  3CLA A;  1Q23 A;  1EAB A;  1EAE A;  1XMC A;  3B30 A;  2RKT A;  1XL7 A;  1DPC A;  5KJT A;  2E1T A;  2E1V A;  2JGP A;  3U9F A;  2IHW A;  2II3 A;  3U9B A;  1DPD A;  1XMD A;  2BGH A;  4N72 A;  5KJS A;  4JN3 A;  3FP0 A;  5DU9 A;  1NOC B;  2E1U A;  4G0B A;  5FAN A;  1XL8 A;  1EAD A;  1CIA A;  5FAL A;  1PD5 A;  1SCZ A;  4G2M A;  2II4 A;  2RKV A;  1EAF A;  1C4T A;  3L60 A;  2VSQ A;  4KE4 A;  1EAC A;  1Q9J A;  2I9D A;  4G22 A;  5DUA A;  5T3E A;  1L5A A;  2XR7 A;  4JN5 A;  1QCA A;  2XHG A;  2ZBA A;  3B2S A;  5KJU A;  5KJV A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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