1EACA

Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
243
structure length
243
Chain Sequence
IPPIPPVDFAKYGEIEEVPMTRLMQIGATNLHRSWLNVPHVTQFESADITELEAFRVAQKAVAKKAGVKLTVLPLLLKACAYLLKELPDFNSSLAPSGQALIRKKYVHIGFAVDTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGACFTISSLGHIGGTAFTPIVNAPEVAILGVSKASMQPVWDGKAFQPRLMLPLSLSYDHRVINGAAAARFTKRLGDLLADIRAILL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
pubmed doi rcsb
molecule tags Dihydrolipoamide acetyltransferase
source organism Azotobacter vinelandii
molecule keywords DIHYDROLIPOYL-TRANSACETYLASE
total genus 67
structure length 243
sequence length 243
ec nomenclature ec 2.3.1.12: Dihydrolipoyllysine-residue acetyltransferase.
pdb deposition date 1992-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 1eacA00
2IHWA 5DU9A 4G2MA 5FALA 1EACA 1CLAA 2RKTA 1DPCA 2XHGA 4KE4A 2II4A 5KJTA 4HVMA 1EAAA 3L60A 1XMDA 2CLAA 5T3EA 2II3A 3B30A 1XMCA 1DPBA 1C4TA 1DPDA 5KJSA 5DUAA 1Q9JA 2E1VA 1EAFA 2ZBAA 2VSQA 3CLAA 3MAEA 3FP0A 4G0BA 1EAEA 4G22A 3U9BA 1CIAA 5KJUA 5FANA 4JN5A 1XL8A 2I9DA 1NOCB 4N72A 1PD5A 5KJWA 2XR7A 1Q23A 1EADA 1XL7A 2II5A 1QCAA 2BGHA 1SCZA 3U9FA 5KJVA 1EABA 2E1UA 3FOTA 2E1TA 2RKVA 4KECA 3B2SA 1L5AA 2JGPA 4JN3A 1E2OA 4CLAA
chains in the Genus database with same CATH superfamily
5DU9A 1CLAA 2XHGA 1DPCA 4HVMA 1XMDA 2II3A 1XMCA 1DPBA 4EP9A 1DPDA 4EPHA 5DUAA 1EAFA 5KJWA 2VSQA 4G0BA 2FY4A 2FY5A 1Q23A 1XL7A 2H4TA 2E1UA 4EYWA 2E1TA 4JN3A 1S5OA 2H3UA 1EACA 2II4A 2H3WA 1NDFA 1C4TA 2FYOA 1Q9JA 2E1VA 2ZBAA 3MAEA 3FP0A 5KJUA 1EAEA 2I9DA 2XR7A 2BGHA 1SCZA 5KJVA 3B2SA 1T7NA 4KECA 2IHWA 5FALA 4KE4A 5KJTA 1EAAA 1T1UA 2FY2A 2RCUA 5T3EA 3B30A 3CLAA 4G22A 3U9BA 1XL8A 1NOCB 1T7QA 1T7OA 1EADA 3FOTA 2FY3A 1L5AA 2RKVA 2JGPA 2FW3A 1E2OA 1Q6XA 4G2MA 2RKTA 3L60A 2CLAA 2DEBA 2H3PA 5KJSA 1CIAA 5FANA 1NDBA 4JN5A 4N72A 1PD5A 2II5A 1QCAA 1NDIA 3U9FA 1EABA 1NM8A 4CLAA
chains in the Genus database with same CATH topology
2IHWA 5DU9A 4G2MA 5FALA 1EACA 1CLAA 2RKTA 1DPCA 2XHGA 4KE4A 2II4A 5KJTA 4HVMA 1EAAA 3L60A 1XMDA 2CLAA 5T3EA 2II3A 3B30A 1XMCA 1DPBA 1C4TA 1DPDA 5KJSA 5DUAA 1Q9JA 2E1VA 1EAFA 2ZBAA 2VSQA 3CLAA 3MAEA 3FP0A 4G0BA 1EAEA 4G22A 3U9BA 1CIAA 5KJUA 5FANA 4JN5A 1XL8A 2I9DA 1NOCB 4N72A 1PD5A 5KJWA 2XR7A 1Q23A 1EADA 1XL7A 2II5A 1QCAA 2BGHA 1SCZA 3U9FA 5KJVA 1EABA 2E1UA 3FOTA 2E1TA 2RKVA 4KECA 3B2SA 1L5AA 2JGPA 4JN3A 1E2OA 4CLAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IHW A;  5DU9 A;  4G2M A;  5FAL A;  1EAC A;  1CLA A;  2RKT A;  1DPC A;  2XHG A;  4KE4 A;  2II4 A;  5KJT A;  4HVM A;  1EAA A;  3L60 A;  1XMD A;  2CLA A;  5T3E A;  2II3 A;  3B30 A;  1XMC A;  1DPB A;  1C4T A;  1DPD A;  5KJS A;  5DUA A;  1Q9J A;  2E1V A;  1EAF A;  2ZBA A;  2VSQ A;  3CLA A;  3MAE A;  3FP0 A;  4G0B A;  1EAE A;  4G22 A;  3U9B A;  1CIA A;  5KJU A;  5FAN A;  4JN5 A;  1XL8 A;  2I9D A;  1NOC B;  4N72 A;  1PD5 A;  5KJW A;  2XR7 A;  1Q23 A;  1EAD A;  1XL7 A;  2II5 A;  1QCA A;  2BGH A;  1SCZ A;  3U9F A;  5KJV A;  1EAB A;  2E1U A;  3FOT A;  2E1T A;  2RKV A;  4KEC A;  3B2S A;  1L5A A;  2JGP A;  4JN3 A;  1E2O A;  4CLA A; 
#chains in the Genus database with same CATH topology
 5DU9 A;  1CLA A;  2XHG A;  1DPC A;  4HVM A;  1XMD A;  2II3 A;  1XMC A;  1DPB A;  4EP9 A;  1DPD A;  4EPH A;  5DUA A;  1EAF A;  5KJW A;  2VSQ A;  4G0B A;  2FY4 A;  2FY5 A;  1Q23 A;  1XL7 A;  2H4T A;  2E1U A;  4EYW A;  2E1T A;  4JN3 A;  1S5O A;  2H3U A;  1EAC A;  2II4 A;  2H3W A;  1NDF A;  1C4T A;  2FYO A;  1Q9J A;  2E1V A;  2ZBA A;  3MAE A;  3FP0 A;  5KJU A;  1EAE A;  2I9D A;  2XR7 A;  2BGH A;  1SCZ A;  5KJV A;  3B2S A;  1T7N A;  4KEC A;  2IHW A;  5FAL A;  4KE4 A;  5KJT A;  1EAA A;  1T1U A;  2FY2 A;  2RCU A;  5T3E A;  3B30 A;  3CLA A;  4G22 A;  3U9B A;  1XL8 A;  1NOC B;  1T7Q A;  1T7O A;  1EAD A;  3FOT A;  2FY3 A;  1L5A A;  2RKV A;  2JGP A;  2FW3 A;  1E2O A;  1Q6X A;  4G2M A;  2RKT A;  3L60 A;  2CLA A;  2DEB A;  2H3P A;  5KJS A;  1CIA A;  5FAN A;  1NDB A;  4JN5 A;  4N72 A;  1PD5 A;  2II5 A;  1QCA A;  1NDI A;  3U9F A;  1EAB A;  1NM8 A;  4CLA A; 
#chains in the Genus database with same CATH homology
 2IHW A;  5DU9 A;  4G2M A;  5FAL A;  1EAC A;  1CLA A;  2RKT A;  1DPC A;  2XHG A;  4KE4 A;  2II4 A;  5KJT A;  4HVM A;  1EAA A;  3L60 A;  1XMD A;  2CLA A;  5T3E A;  2II3 A;  3B30 A;  1XMC A;  1DPB A;  1C4T A;  1DPD A;  5KJS A;  5DUA A;  1Q9J A;  2E1V A;  1EAF A;  2ZBA A;  2VSQ A;  3CLA A;  3MAE A;  3FP0 A;  4G0B A;  1EAE A;  4G22 A;  3U9B A;  1CIA A;  5KJU A;  5FAN A;  4JN5 A;  1XL8 A;  2I9D A;  1NOC B;  4N72 A;  1PD5 A;  5KJW A;  2XR7 A;  1Q23 A;  1EAD A;  1XL7 A;  2II5 A;  1QCA A;  2BGH A;  1SCZ A;  3U9F A;  5KJV A;  1EAB A;  2E1U A;  3FOT A;  2E1T A;  2RKV A;  4KEC A;  3B2S A;  1L5A A;  2JGP A;  4JN3 A;  1E2O A;  4CLA A; 
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similar chains in the pdb database (?% sequence similarity)

 
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