1EADA

Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
243
structure length
243
Chain Sequence
IPPIPPVDFAKYGEIEEVPMTRLMQIGATNLHRSWLNVPHVTQFESADITELEAFRVAQKAVAKKAGVKLTVLPLLLKACAYLLKELPDFNSSLAPSGQALIRKKYVHIGFAVDTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGACFTISSLGHIGGTAFTPIVNAPEVAILGVSKASMQPVWDGKAFQPRLMLPLSLSYDHRVINGAAAARFTKRLGDLLADIRAILL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
pubmed doi rcsb
molecule tags Dihydrolipoamide acetyltransferase
source organism Azotobacter vinelandii
molecule keywords DIHYDROLIPOYL-TRANSACETYLASE
total genus 65
structure length 243
sequence length 243
ec nomenclature ec 2.3.1.12: Dihydrolipoyllysine-residue acetyltransferase.
pdb deposition date 1992-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 1eadA00
1EADA 1DPBA 1SCZA 2BGHA 1C4TA 5KJUA 1XMDA 1PD5A 1DPDA 2E1UA 3U9FA 3B2SA 3FP0A 3FOTA 5FALA 2RKTA 2I9DA 1EACA 5KJWA 2CLAA 2JGPA 4G2MA 4JN5A 5T3EA 1CIAA 1E2OA 1XMCA 4G0BA 5KJSA 1XL7A 1EAEA 2XHGA 5DU9A 4G22A 2RKVA 2II5A 2VSQA 3CLAA 2II3A 1QCAA 2XR7A 4KE4A 2E1VA 1DPCA 5KJVA 1EABA 4KECA 1XL8A 2II4A 1EAAA 1EAFA 5KJTA 1Q9JA 3U9BA 1L5AA 2ZBAA 3MAEA 1NOCB 5DUAA 5FANA 2IHWA 4JN3A 2E1TA 4N72A 3L60A 4CLAA 1CLAA 4HVMA 1Q23A 3B30A
chains in the Genus database with same CATH superfamily
1EADA 1DPBA 1SCZA 1PD5A 3U9FA 3B2SA 2H4TA 3FOTA 2CLAA 1E2OA 2II5A 1T7NA 2II3A 1NDFA 5KJTA 1L5AA 2FY2A 1NOCB 2FY3A 5DUAA 1CLAA 4EYWA 2I9DA 2RCUA 2BGHA 2FY4A 2FW3A 5KJUA 1DPDA 5FALA 4G0BA 4G22A 1NDBA 4KECA 1EAAA 2ZBAA 2FYOA 5FANA 2IHWA 4N72A 2FY5A 1C4TA 2E1UA 5KJWA 2JGPA 5T3EA 4JN5A 2H3WA 2XHGA 5DU9A 2RKVA 3CLAA 2VSQA 2XR7A 4KE4A 2E1VA 1DPCA 5KJVA 1EABA 1T1UA 1T7QA 1XL8A 1NM8A 3U9BA 3MAEA 2E1TA 4CLAA 3L60A 4JN3A 1Q23A 2H3PA 2H3UA 1T7OA 1XMDA 3FP0A 2RKTA 1EACA 4G2MA 1CIAA 1XMCA 5KJSA 1XL7A 1EAEA 4EP9A 2DEBA 1QCAA 4EPHA 2II4A 1EAFA 1Q9JA 1NDIA 1Q6XA 4HVMA 1S5OA 3B30A
chains in the Genus database with same CATH topology
1EADA 1DPBA 1SCZA 2BGHA 1C4TA 5KJUA 1XMDA 1PD5A 1DPDA 2E1UA 3U9FA 3B2SA 3FP0A 3FOTA 5FALA 2RKTA 2I9DA 1EACA 5KJWA 2CLAA 2JGPA 4G2MA 4JN5A 5T3EA 1CIAA 1E2OA 1XMCA 4G0BA 5KJSA 1XL7A 1EAEA 2XHGA 5DU9A 4G22A 2RKVA 2II5A 2VSQA 3CLAA 2II3A 1QCAA 2XR7A 4KE4A 2E1VA 1DPCA 5KJVA 1EABA 4KECA 1XL8A 2II4A 1EAAA 1EAFA 5KJTA 1Q9JA 3U9BA 1L5AA 2ZBAA 3MAEA 1NOCB 5DUAA 5FANA 2IHWA 4JN3A 2E1TA 4N72A 3L60A 4CLAA 1CLAA 4HVMA 1Q23A 3B30A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EAD A;  1DPB A;  1SCZ A;  2BGH A;  1C4T A;  5KJU A;  1XMD A;  1PD5 A;  1DPD A;  2E1U A;  3U9F A;  3B2S A;  3FP0 A;  3FOT A;  5FAL A;  2RKT A;  2I9D A;  1EAC A;  5KJW A;  2CLA A;  2JGP A;  4G2M A;  4JN5 A;  5T3E A;  1CIA A;  1E2O A;  1XMC A;  4G0B A;  5KJS A;  1XL7 A;  1EAE A;  2XHG A;  5DU9 A;  4G22 A;  2RKV A;  2II5 A;  2VSQ A;  3CLA A;  2II3 A;  1QCA A;  2XR7 A;  4KE4 A;  2E1V A;  1DPC A;  5KJV A;  1EAB A;  4KEC A;  1XL8 A;  2II4 A;  1EAA A;  1EAF A;  5KJT A;  1Q9J A;  3U9B A;  1L5A A;  2ZBA A;  3MAE A;  1NOC B;  5DUA A;  5FAN A;  2IHW A;  4JN3 A;  2E1T A;  4N72 A;  3L60 A;  4CLA A;  1CLA A;  4HVM A;  1Q23 A;  3B30 A; 
#chains in the Genus database with same CATH topology
 1EAD A;  1DPB A;  1SCZ A;  1PD5 A;  3U9F A;  3B2S A;  2H4T A;  3FOT A;  2CLA A;  1E2O A;  2II5 A;  1T7N A;  2II3 A;  1NDF A;  5KJT A;  1L5A A;  2FY2 A;  1NOC B;  2FY3 A;  5DUA A;  1CLA A;  4EYW A;  2I9D A;  2RCU A;  2BGH A;  2FY4 A;  2FW3 A;  5KJU A;  1DPD A;  5FAL A;  4G0B A;  4G22 A;  1NDB A;  4KEC A;  1EAA A;  2ZBA A;  2FYO A;  5FAN A;  2IHW A;  4N72 A;  2FY5 A;  1C4T A;  2E1U A;  5KJW A;  2JGP A;  5T3E A;  4JN5 A;  2H3W A;  2XHG A;  5DU9 A;  2RKV A;  3CLA A;  2VSQ A;  2XR7 A;  4KE4 A;  2E1V A;  1DPC A;  5KJV A;  1EAB A;  1T1U A;  1T7Q A;  1XL8 A;  1NM8 A;  3U9B A;  3MAE A;  2E1T A;  4CLA A;  3L60 A;  4JN3 A;  1Q23 A;  2H3P A;  2H3U A;  1T7O A;  1XMD A;  3FP0 A;  2RKT A;  1EAC A;  4G2M A;  1CIA A;  1XMC A;  5KJS A;  1XL7 A;  1EAE A;  4EP9 A;  2DEB A;  1QCA A;  4EPH A;  2II4 A;  1EAF A;  1Q9J A;  1NDI A;  1Q6X A;  4HVM A;  1S5O A;  3B30 A; 
#chains in the Genus database with same CATH homology
 1EAD A;  1DPB A;  1SCZ A;  2BGH A;  1C4T A;  5KJU A;  1XMD A;  1PD5 A;  1DPD A;  2E1U A;  3U9F A;  3B2S A;  3FP0 A;  3FOT A;  5FAL A;  2RKT A;  2I9D A;  1EAC A;  5KJW A;  2CLA A;  2JGP A;  4G2M A;  4JN5 A;  5T3E A;  1CIA A;  1E2O A;  1XMC A;  4G0B A;  5KJS A;  1XL7 A;  1EAE A;  2XHG A;  5DU9 A;  4G22 A;  2RKV A;  2II5 A;  2VSQ A;  3CLA A;  2II3 A;  1QCA A;  2XR7 A;  4KE4 A;  2E1V A;  1DPC A;  5KJV A;  1EAB A;  4KEC A;  1XL8 A;  2II4 A;  1EAA A;  1EAF A;  5KJT A;  1Q9J A;  3U9B A;  1L5A A;  2ZBA A;  3MAE A;  1NOC B;  5DUA A;  5FAN A;  2IHW A;  4JN3 A;  2E1T A;  4N72 A;  3L60 A;  4CLA A;  1CLA A;  4HVM A;  1Q23 A;  3B30 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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