1EAEA

Atomic structure of the cubic core of the pyruvate dehydrogenase multienzyme complex
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
243
structure length
243
Chain Sequence
IPPIPPVDFAKYGEIEEVPMTRLMQIGATNLHRSWLNVPHVTQFESADITELEAFRVAQKAVAKKAGVKLTVLPLLLKACAYLLKELPDFNSSLAPSGQALIRKKYVHIGFAVDTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGACFTISSLGHIGGTAFTPIVNAPEVAILGVSKASMQPVWDGKAFQPRLMLPLSLSYDHRVINGAAAARFTKRLGDLLADIRAILL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
pubmed doi rcsb
molecule tags Dihydrolipoamide acetyltransferase
source organism Azotobacter vinelandii
molecule keywords DIHYDROLIPOYL-TRANSACETYLASE
total genus 67
structure length 243
sequence length 243
ec nomenclature ec 2.3.1.12: Dihydrolipoyllysine-residue acetyltransferase.
pdb deposition date 1992-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00198 2-oxoacid_dh 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 1eaeA00
1EACA 3CLAA 1EAAA 1Q9JA 1XL7A 2RKVA 2CLAA 2E1UA 4CLAA 5DUAA 2I9DA 4G2MA 4JN3A 4KE4A 5T3EA 1EAEA 1NOCB 2JGPA 2IHWA 5KJVA 1QCAA 1CLAA 2II4A 3MAEA 3U9FA 1DPDA 5KJSA 4KECA 5DU9A 1L5AA 1PD5A 4N72A 5KJUA 2ZBAA 1EABA 1E2OA 2II3A 4G0BA 4JN5A 1C4TA 1DPCA 1EADA 1XMCA 2RKTA 3B30A 1XL8A 2XHGA 1Q23A 1DPBA 2VSQA 3FP0A 1SCZA 2XR7A 1EAFA 2BGHA 5FALA 5FANA 1XMDA 4G22A 5KJTA 1CIAA 4HVMA 3FOTA 3U9BA 2E1TA 2II5A 3B2SA 3L60A 5KJWA 2E1VA
chains in the Genus database with same CATH superfamily
1XL7A 2RCUA 5DUAA 2FY5A 5T3EA 4EYWA 4KE4A 1CLAA 4G0BA 2RKTA 2FYOA 2H3UA 2XHGA 1NDFA 2VSQA 3FP0A 1SCZA 2BGHA 1NM8A 1EAAA 2FY3A 1T7NA 1NDIA 2I9DA 4JN3A 1QCAA 2II4A 4KECA 5KJUA 1PD5A 2ZBAA 1E2OA 1T7OA 2FW3A 2H4TA 1T7QA 1C4TA 1DPCA 1EADA 2XR7A 1EAFA 5FALA 1XMDA 3U9BA 2E1TA 2II5A 3L60A 2FY4A 1EACA 3CLAA 1Q9JA 2CLAA 1EAEA 3U9FA 1DPDA 5KJSA 2H3PA 1EABA 2II3A 4JN5A 3B30A 1XL8A 1Q23A 1DPBA 5FANA 4G22A 4HVMA 3B2SA 1Q6XA 2RKVA 2H3WA 2E1UA 4CLAA 2DEBA 4G2MA 1NOCB 2JGPA 2IHWA 5KJVA 4EP9A 3MAEA 5DU9A 1L5AA 4N72A 2FY2A 1XMCA 1S5OA 1NDBA 4EPHA 5KJTA 1CIAA 3FOTA 1T1UA 5KJWA 2E1VA
chains in the Genus database with same CATH topology
1EACA 3CLAA 1EAAA 1Q9JA 1XL7A 2RKVA 2CLAA 2E1UA 4CLAA 5DUAA 2I9DA 4G2MA 4JN3A 4KE4A 5T3EA 1EAEA 1NOCB 2JGPA 2IHWA 5KJVA 1QCAA 1CLAA 2II4A 3MAEA 3U9FA 1DPDA 5KJSA 4KECA 5DU9A 1L5AA 1PD5A 4N72A 5KJUA 2ZBAA 1EABA 1E2OA 2II3A 4G0BA 4JN5A 1C4TA 1DPCA 1EADA 1XMCA 2RKTA 3B30A 1XL8A 2XHGA 1Q23A 1DPBA 2VSQA 3FP0A 1SCZA 2XR7A 1EAFA 2BGHA 5FALA 5FANA 1XMDA 4G22A 5KJTA 1CIAA 4HVMA 3FOTA 3U9BA 2E1TA 2II5A 3B2SA 3L60A 5KJWA 2E1VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EAC A;  3CLA A;  1EAA A;  1Q9J A;  1XL7 A;  2RKV A;  2CLA A;  2E1U A;  4CLA A;  5DUA A;  2I9D A;  4G2M A;  4JN3 A;  4KE4 A;  5T3E A;  1EAE A;  1NOC B;  2JGP A;  2IHW A;  5KJV A;  1QCA A;  1CLA A;  2II4 A;  3MAE A;  3U9F A;  1DPD A;  5KJS A;  4KEC A;  5DU9 A;  1L5A A;  1PD5 A;  4N72 A;  5KJU A;  2ZBA A;  1EAB A;  1E2O A;  2II3 A;  4G0B A;  4JN5 A;  1C4T A;  1DPC A;  1EAD A;  1XMC A;  2RKT A;  3B30 A;  1XL8 A;  2XHG A;  1Q23 A;  1DPB A;  2VSQ A;  3FP0 A;  1SCZ A;  2XR7 A;  1EAF A;  2BGH A;  5FAL A;  5FAN A;  1XMD A;  4G22 A;  5KJT A;  1CIA A;  4HVM A;  3FOT A;  3U9B A;  2E1T A;  2II5 A;  3B2S A;  3L60 A;  5KJW A;  2E1V A; 
#chains in the Genus database with same CATH topology
 1XL7 A;  2RCU A;  5DUA A;  2FY5 A;  5T3E A;  4EYW A;  4KE4 A;  1CLA A;  4G0B A;  2RKT A;  2FYO A;  2H3U A;  2XHG A;  1NDF A;  2VSQ A;  3FP0 A;  1SCZ A;  2BGH A;  1NM8 A;  1EAA A;  2FY3 A;  1T7N A;  1NDI A;  2I9D A;  4JN3 A;  1QCA A;  2II4 A;  4KEC A;  5KJU A;  1PD5 A;  2ZBA A;  1E2O A;  1T7O A;  2FW3 A;  2H4T A;  1T7Q A;  1C4T A;  1DPC A;  1EAD A;  2XR7 A;  1EAF A;  5FAL A;  1XMD A;  3U9B A;  2E1T A;  2II5 A;  3L60 A;  2FY4 A;  1EAC A;  3CLA A;  1Q9J A;  2CLA A;  1EAE A;  3U9F A;  1DPD A;  5KJS A;  2H3P A;  1EAB A;  2II3 A;  4JN5 A;  3B30 A;  1XL8 A;  1Q23 A;  1DPB A;  5FAN A;  4G22 A;  4HVM A;  3B2S A;  1Q6X A;  2RKV A;  2H3W A;  2E1U A;  4CLA A;  2DEB A;  4G2M A;  1NOC B;  2JGP A;  2IHW A;  5KJV A;  4EP9 A;  3MAE A;  5DU9 A;  1L5A A;  4N72 A;  2FY2 A;  1XMC A;  1S5O A;  1NDB A;  4EPH A;  5KJT A;  1CIA A;  3FOT A;  1T1U A;  5KJW A;  2E1V A; 
#chains in the Genus database with same CATH homology
 1EAC A;  3CLA A;  1EAA A;  1Q9J A;  1XL7 A;  2RKV A;  2CLA A;  2E1U A;  4CLA A;  5DUA A;  2I9D A;  4G2M A;  4JN3 A;  4KE4 A;  5T3E A;  1EAE A;  1NOC B;  2JGP A;  2IHW A;  5KJV A;  1QCA A;  1CLA A;  2II4 A;  3MAE A;  3U9F A;  1DPD A;  5KJS A;  4KEC A;  5DU9 A;  1L5A A;  1PD5 A;  4N72 A;  5KJU A;  2ZBA A;  1EAB A;  1E2O A;  2II3 A;  4G0B A;  4JN5 A;  1C4T A;  1DPC A;  1EAD A;  1XMC A;  2RKT A;  3B30 A;  1XL8 A;  2XHG A;  1Q23 A;  1DPB A;  2VSQ A;  3FP0 A;  1SCZ A;  2XR7 A;  1EAF A;  2BGH A;  5FAL A;  5FAN A;  1XMD A;  4G22 A;  5KJT A;  1CIA A;  4HVM A;  3FOT A;  3U9B A;  2E1T A;  2II5 A;  3B2S A;  3L60 A;  5KJW A;  2E1V A; 
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