1Q23A

Crystal structure of chloramphenicol acetyltransferase i complexed with fusidic acid at 2.18 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
214
structure length
214
Chain Sequence
ITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAFLKTVKKNKHKFYPAFIHILARLMNAHPEFRMAMKDGELVIWDSVHPCYTVFHEQTETFSSLWSEYHDDFRQFLHIYSQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNVANMDNFFAPVFTMGKYYTQGDKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Escherichia coli
publication title Crystal structure of Chloramphenicol acetyltransferase I in the apoenzyme form and complexed with fusidic acid at 2.18 A resolution
rcsb
molecule keywords Chloramphenicol acetyltransferase
total genus 63
structure length 214
sequence length 214
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L
ec nomenclature ec 2.3.1.28: Chloramphenicol O-acetyltransferase.
pdb deposition date 2003-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00302 CAT Chloramphenicol acetyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 1q23A00
1EACA 4G2MA 1EAFA 2II4A 2RKVA 2CLAA 2XR7A 4KE4A 4JN5A 2RKTA 4G22A 1DPDA 3CLAA 3B2SA 1DPBA 2ZBAA 2JGPA 3L60A 2E1TA 2VSQA 1XMCA 5FANA 3U9BA 1EAEA 3U9FA 1CIAA 1Q9JA 1XL8A 2BGHA 2E1UA 2E1VA 5DU9A 4JN3A 1CLAA 1L5AA 5KJSA 1DPCA 1SCZA 1C4TA 1XMDA 2I9DA 5FALA 3MAEA 2IHWA 2II3A 5KJTA 5T3EA 5KJWA 1XL7A 4HVMA 1NOCB 1Q23A 4KECA 2XHGA 4N72A 5KJVA 1QCAA 1PD5A 3FP0A 2II5A 4G0BA 5DUAA 5KJUA 1EABA 3FOTA 4CLAA 3B30A 1EADA 1E2OA 1EAAA
chains in the Genus database with same CATH superfamily
4G2MA 1EAFA 2II4A 1NDFA 2XR7A 4KE4A 1NM8A 1T7OA 2JGPA 5KJSA 2H3PA 4JN3A 2FY2A 2FYOA 2DEBA 3MAEA 2II3A 5KJWA 4HVMA 2XHGA 2FW3A 5KJVA 5KJUA 1EABA 3FOTA 3B30A 1Q6XA 1EACA 2RKVA 1NDIA 1DPDA 3B2SA 1DPBA 3L60A 2E1TA 2VSQA 5FANA 3U9BA 2BGHA 2E1UA 5DU9A 1L5AA 1CLAA 2FY5A 2FY3A 1C4TA 2H3UA 2I9DA 2IHWA 1T1UA 2H3WA 4EPHA 4G0BA 3FP0A 5DUAA 2RCUA 2H4TA 1S5OA 2CLAA 2RKTA 1XMCA 3U9FA 1EAEA 1CIAA 1Q9JA 1XL8A 2E1VA 4EYWA 1DPCA 1SCZA 1XMDA 5FALA 5KJTA 5T3EA 1XL7A 1Q23A 1PD5A 2II5A 4JN5A 1EADA 1T7NA 4EP9A 4G22A 3CLAA 2ZBAA 1T7QA 2FY4A 1NOCB 4KECA 1NDBA 4N72A 1QCAA 4CLAA 1E2OA 1EAAA
chains in the Genus database with same CATH topology
1EACA 4G2MA 1EAFA 2II4A 2RKVA 2CLAA 2XR7A 4KE4A 4JN5A 2RKTA 4G22A 1DPDA 3CLAA 3B2SA 1DPBA 2ZBAA 2JGPA 3L60A 2E1TA 2VSQA 1XMCA 5FANA 3U9BA 1EAEA 3U9FA 1CIAA 1Q9JA 1XL8A 2BGHA 2E1UA 2E1VA 5DU9A 4JN3A 1CLAA 1L5AA 5KJSA 1DPCA 1SCZA 1C4TA 1XMDA 2I9DA 5FALA 3MAEA 2IHWA 2II3A 5KJTA 5T3EA 5KJWA 1XL7A 4HVMA 1NOCB 1Q23A 4KECA 2XHGA 4N72A 5KJVA 1QCAA 1PD5A 3FP0A 2II5A 4G0BA 5DUAA 5KJUA 1EABA 3FOTA 4CLAA 3B30A 1EADA 1E2OA 1EAAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EAC A;  4G2M A;  1EAF A;  2II4 A;  2RKV A;  2CLA A;  2XR7 A;  4KE4 A;  4JN5 A;  2RKT A;  4G22 A;  1DPD A;  3CLA A;  3B2S A;  1DPB A;  2ZBA A;  2JGP A;  3L60 A;  2E1T A;  2VSQ A;  1XMC A;  5FAN A;  3U9B A;  1EAE A;  3U9F A;  1CIA A;  1Q9J A;  1XL8 A;  2BGH A;  2E1U A;  2E1V A;  5DU9 A;  4JN3 A;  1CLA A;  1L5A A;  5KJS A;  1DPC A;  1SCZ A;  1C4T A;  1XMD A;  2I9D A;  5FAL A;  3MAE A;  2IHW A;  2II3 A;  5KJT A;  5T3E A;  5KJW A;  1XL7 A;  4HVM A;  1NOC B;  1Q23 A;  4KEC A;  2XHG A;  4N72 A;  5KJV A;  1QCA A;  1PD5 A;  3FP0 A;  2II5 A;  4G0B A;  5DUA A;  5KJU A;  1EAB A;  3FOT A;  4CLA A;  3B30 A;  1EAD A;  1E2O A;  1EAA A; 
#chains in the Genus database with same CATH topology
 4G2M A;  1EAF A;  2II4 A;  1NDF A;  2XR7 A;  4KE4 A;  1NM8 A;  1T7O A;  2JGP A;  5KJS A;  2H3P A;  4JN3 A;  2FY2 A;  2FYO A;  2DEB A;  3MAE A;  2II3 A;  5KJW A;  4HVM A;  2XHG A;  2FW3 A;  5KJV A;  5KJU A;  1EAB A;  3FOT A;  3B30 A;  1Q6X A;  1EAC A;  2RKV A;  1NDI A;  1DPD A;  3B2S A;  1DPB A;  3L60 A;  2E1T A;  2VSQ A;  5FAN A;  3U9B A;  2BGH A;  2E1U A;  5DU9 A;  1L5A A;  1CLA A;  2FY5 A;  2FY3 A;  1C4T A;  2H3U A;  2I9D A;  2IHW A;  1T1U A;  2H3W A;  4EPH A;  4G0B A;  3FP0 A;  5DUA A;  2RCU A;  2H4T A;  1S5O A;  2CLA A;  2RKT A;  1XMC A;  3U9F A;  1EAE A;  1CIA A;  1Q9J A;  1XL8 A;  2E1V A;  4EYW A;  1DPC A;  1SCZ A;  1XMD A;  5FAL A;  5KJT A;  5T3E A;  1XL7 A;  1Q23 A;  1PD5 A;  2II5 A;  4JN5 A;  1EAD A;  1T7N A;  4EP9 A;  4G22 A;  3CLA A;  2ZBA A;  1T7Q A;  2FY4 A;  1NOC B;  4KEC A;  1NDB A;  4N72 A;  1QCA A;  4CLA A;  1E2O A;  1EAA A; 
#chains in the Genus database with same CATH homology
 1EAC A;  4G2M A;  1EAF A;  2II4 A;  2RKV A;  2CLA A;  2XR7 A;  4KE4 A;  4JN5 A;  2RKT A;  4G22 A;  1DPD A;  3CLA A;  3B2S A;  1DPB A;  2ZBA A;  2JGP A;  3L60 A;  2E1T A;  2VSQ A;  1XMC A;  5FAN A;  3U9B A;  1EAE A;  3U9F A;  1CIA A;  1Q9J A;  1XL8 A;  2BGH A;  2E1U A;  2E1V A;  5DU9 A;  4JN3 A;  1CLA A;  1L5A A;  5KJS A;  1DPC A;  1SCZ A;  1C4T A;  1XMD A;  2I9D A;  5FAL A;  3MAE A;  2IHW A;  2II3 A;  5KJT A;  5T3E A;  5KJW A;  1XL7 A;  4HVM A;  1NOC B;  1Q23 A;  4KEC A;  2XHG A;  4N72 A;  5KJV A;  1QCA A;  1PD5 A;  3FP0 A;  2II5 A;  4G0B A;  5DUA A;  5KJU A;  1EAB A;  3FOT A;  4CLA A;  3B30 A;  1EAD A;  1E2O A;  1EAA A; 
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similar chains in the Genus database (?% sequence similarity)
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