1Q6XA

Crystal structure of rat choline acetyltransferase
Total Genus 215
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
215
sequence length
600
structure length
600
Chain Sequence
WEELDLPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQLRFAACLISGVLSYKTLLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGELSDTHRALQLLHGGGCSLNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRLRWKCSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRLYQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQAQTEYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEMFCCYGPVVPNGYGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSSR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords choline O-acetyltransferase
total genus 215
structure length 600
sequence length 600
chains with identical sequence B
ec nomenclature ec 2.3.1.6: Choline O-acetyltransferase.
pdb deposition date 2003-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00755 Carn_acyltransf Choline/Carnitine o-acyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.40 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1q6xA01
3.30.559.70 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 1q6xA02
1NM8A 1T7QA 4EYWA 2H3UA 2DEBA 1S5OA 2H3WA 2FY5A 1T7OA 2FYOA 1NDBA 2H3PA 1Q6XA 1T7NA 2FY4A 4EPHA 2RCUA 2H4TA 2FY3A 2FW3A 1NDFA 4EP9A 1T1UA 1NDIA 2FY2A
chains in the Genus database with same CATH superfamily
2CLAA 2H3UA 3B2SA 4JN3A 1PD5A 1DPCA 5DUAA 1E2OA 2VSQA 5FANA 3U9FA 1XL7A 2XR7A 5KJWA 3FOTA 2H3PA 2II4A 3B30A 1SCZA 1XMDA 4EPHA 4HVMA 2E1VA 1Q9JA 2JGPA 2XHGA 2ZBAA 2FY2A 2E1TA 1NM8A 1EAEA 1T7QA 1DPDA 4EYWA 1T7OA 2BGHA 4G22A 1NDBA 1NOCB 1DPBA 1XMCA 4CLAA 1C4TA 2RKTA 1T7NA 3FP0A 5DU9A 2FY4A 2II5A 2RCUA 4G0BA 5KJVA 5KJSA 2FY3A 5FALA 1EAAA 2IHWA 1T1UA 2DEBA 1EABA 4G2MA 4N72A 1EADA 4KE4A 1EACA 1XL8A 2E1UA 3MAEA 2II3A 3U9BA 1EAFA 1L5AA 4EP9A 5T3EA 2I9DA 1QCAA 1S5OA 5KJTA 3L60A 2H3WA 5KJUA 2FY5A 2FYOA 1CIAA 2RKVA 3CLAA 1Q23A 1Q6XA 4KECA 2H4TA 2FW3A 1NDFA 4JN5A 1CLAA 1NDIA
chains in the Genus database with same CATH topology
1NM8A 1T7QA 4EYWA 2H3UA 2DEBA 4JN3A 1S5OA 5T3EA 5DUAA 2H3WA 2VSQA 2FY5A 1T7OA 2FYOA 1NDBA 3FOTA 2H3PA 1Q6XA 1T7NA 3FP0A 5DU9A 2FY4A 4HVMA 4EPHA 2RCUA 2H4TA 2FY3A 2FW3A 1NDFA 1Q9JA 2JGPA 1L5AA 2XHGA 4EP9A 4JN5A 1T1UA 1NDIA 2FY2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NM8 A;  1T7Q A;  4EYW A;  2H3U A;  2DEB A;  1S5O A;  2H3W A;  2FY5 A;  1T7O A;  2FYO A;  1NDB A;  2H3P A;  1Q6X A;  1T7N A;  2FY4 A;  4EPH A;  2RCU A;  2H4T A;  2FY3 A;  2FW3 A;  1NDF A;  4EP9 A;  1T1U A;  1NDI A;  2FY2 A; 
#chains in the Genus database with same CATH topology
 2CLA A;  2H3U A;  3B2S A;  4JN3 A;  1PD5 A;  1DPC A;  5DUA A;  1E2O A;  2VSQ A;  5FAN A;  3U9F A;  1XL7 A;  2XR7 A;  5KJW A;  3FOT A;  2H3P A;  2II4 A;  3B30 A;  1SCZ A;  1XMD A;  4EPH A;  4HVM A;  2E1V A;  1Q9J A;  2JGP A;  2XHG A;  2ZBA A;  2FY2 A;  2E1T A;  1NM8 A;  1EAE A;  1T7Q A;  1DPD A;  4EYW A;  1T7O A;  2BGH A;  4G22 A;  1NDB A;  1NOC B;  1DPB A;  1XMC A;  4CLA A;  1C4T A;  2RKT A;  1T7N A;  3FP0 A;  5DU9 A;  2FY4 A;  2II5 A;  2RCU A;  4G0B A;  5KJV A;  5KJS A;  2FY3 A;  5FAL A;  1EAA A;  2IHW A;  1T1U A;  2DEB A;  1EAB A;  4G2M A;  4N72 A;  1EAD A;  4KE4 A;  1EAC A;  1XL8 A;  2E1U A;  3MAE A;  2II3 A;  3U9B A;  1EAF A;  1L5A A;  4EP9 A;  5T3E A;  2I9D A;  1QCA A;  1S5O A;  5KJT A;  3L60 A;  2H3W A;  5KJU A;  2FY5 A;  2FYO A;  1CIA A;  2RKV A;  3CLA A;  1Q23 A;  1Q6X A;  4KEC A;  2H4T A;  2FW3 A;  1NDF A;  4JN5 A;  1CLA A;  1NDI A; 
#chains in the Genus database with same CATH homology
 1NM8 A;  1T7Q A;  4EYW A;  2H3U A;  2DEB A;  4JN3 A;  1S5O A;  5T3E A;  5DUA A;  2H3W A;  2VSQ A;  2FY5 A;  1T7O A;  2FYO A;  1NDB A;  3FOT A;  2H3P A;  1Q6X A;  1T7N A;  3FP0 A;  5DU9 A;  2FY4 A;  4HVM A;  4EPH A;  2RCU A;  2H4T A;  2FY3 A;  2FW3 A;  1NDF A;  1Q9J A;  2JGP A;  1L5A A;  2XHG A;  4EP9 A;  4JN5 A;  1T1U A;  1NDI A;  2FY2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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